جستجوی استاد راهنمای دانشگاهی

• Plant Genomics
• Machine Learning
• Computational Biology
• +۵ مورد دیگر

Philipp Bayer is an Adjunct Research Fellow at the University of Western Australia (UWA) and a Principal in the OceanOmics project at the Minderoo Foundation. His roles include computational biology research focused on plant genomics, machine learning applications in genomics, and environmental DNA (eDNA) methods for ocean biodiversity monitoring. He holds a PhD from the University of Queensland (UQ) and has held positions such as a Forrest Fellowship and DECRA fellowship, focusing on wheat breeding and evolutionary genomics. Bayer is a member of the UWA Data Institute's Research Committee and the Scientific Advisory Committee for the ARDC Machine Learning CoP. Education and Career Highlights: PhD in Plant Genomics, UQ (2016) DECRA Fellowship at UWA (2021–2023), studying plant gene evolution Forrest Fellowship (2018–2020) on wheat genomics and machine learning Principal, Computational Biology, Minderoo Foundation (2022–present) Research Interests: Plant pangenomics and genome evolution Machine learning for crop improvement and biodiversity analysis eDNA-based marine biodiversity monitoring Genetic mechanisms underlying crop domestication Grants and Collaborations: GRDC: Machine learning for canola disease resistance ARC DECRA: Evolutionary genomics of plant genes Collaborations with BASF, Intergrain, and the OceanOmics initiative Awards: Finalist in the 2019 WA Premier’s Science Award. Labs/Teams: Leads the OceanOmics project and organizes Hacky Hour (code/data support sessions).

Susan A. Martinisمشاهده پروفایل

استاد

• Enzymology
• Molecular Evolution
• Protein-Nucleic Acid Interactions
• +۵ مورد دیگر

Susan A. Martinis is the Vice Chancellor for Research and Innovation at the University of Illinois at Urbana-Champaign, where she holds dual appointments as Professor of Biochemistry and Stephen G. Sligar Professor of Molecular and Cellular Biology, and Professor of Biophysics and Quantitative Biology. Her research laboratory focuses on the molecular mechanisms of tRNA synthetases, essential enzymes governing protein synthesis fidelity through aminoacylation and editing activities. Research interests span enzymology, RNA biology, molecular evolution, and protein-nucleic acid interactions, with emphasis on: Fidelity mechanisms in tRNA synthetases, particularly leucyl-tRNA synthetase (LeuRS) Proofreading and editing pathways preventing translational errors Mitochondrial group I intron splicing mediated by LeuRS Engineering tRNA synthetases for genetic code expansion applications Her publications demonstrate sustained focus on enzyme kinetics, structural biology of synthetases, and therapeutic targeting of pathogen-specific editing mechanisms. Recent work explores benzoxaborole inhibitors, evolutionary adaptations in Mycoplasma, and non-canonical roles in gene regulation. Martinis leads an active research group (Martinis Lab) investigating novel synthetase functions beyond translation. Current projects examine splicing-activation domains, CP1 domain evolution, and amino acid editing dynamics using biochemical, structural, and computational approaches.

Henri Tiedgeمشاهده پروفایل

استاد

• RNA Biology
• Neurobiology
• Translational Regulation
• +۵ مورد دیگر

Henri Tiedge, PhD , is a Professor at the Department of Physiology and Pharmacology within SUNY Downstate Medical Center . His research focuses on regulatory brain cytoplasmic (BC) RNAs , particularly their role in translational control mechanisms at neuronal synapses and their implications in neurological disorders and tumor biology . Institutional Affiliation: SUNY Downstate Medical Center (College of Medicine, Physiology and Pharmacology) Academic Rank: Professor Research Domains: RNA Biology, Synaptic Plasticity, Neurodegeneration, Oncology Dr. Tiedge investigates how BC1 and BC200 RNAs regulate local protein synthesis in dendrites through interactions with eukaryotic initiation factors (eIF4A/B) . His work demonstrates that BC RNA dysregulation leads to neuronal hyperexcitability , epileptogenesis , and cognitive dysfunction , with therapeutic applications in neuropsychiatric lupus using RNA decoys. He also explores BC RNA expression in germ cells and tumors , aiming to develop diagnostic/prognostic tools for cancer. Key publications include studies on RNA transport via hnRNP A2 and Purα , autoantibody-induced RNA displacement , and cross-talk between BC RNAs and FMRP in fragile X syndrome. His work has been supported by NIH grants NS046769 and DA026110 .

• Head and Neck Cancer
• Thyroid Carcinoma
• Molecular Pathology
• +۳ مورد دیگر

Ying-Hsia Chu serves as Assistant Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota, where she leads research at the intersection of molecular pathology and head/neck-thyroid oncology. Her work bridges diagnostic histopathology with genomic characterization to address clinically challenging carcinomas. Research Focus: Dr. Chu specializes in gene fusion discovery (e.g., STAT6, RAF1, NOTCH1), non-coding RNA mechanisms in cancer progression, and development of RNA sequencing diagnostics for sinonasal tract and thyroid malignancies. Her fingerprint analysis confirms dominant expertise in neoplasm (100%), thyroid carcinoma (84%), and phosphotransferase pathways (69%), with significant contributions to understanding long non-coding RNAs in anaplastic carcinomas. Publication Trends: Analysis of her 35 publications (2013-2025) reveals accelerating output since 2020, with 2022-2025 works emphasizing actionable genomic alterations (e.g., FGFR rearrangements, MET skipping) and expanded histological spectra in HPV-associated carcinomas. This trajectory demonstrates increasing influence in precision oncology diagnostics, particularly through multi-institutional collaborations. Collaborative Impact: Dr. Chu's nationwide studies on oral cavity cancer (e.g., 2023 neck dissection analysis with 18 Scopus citations) demonstrate translational impact on surgical guidelines. Her work engages international networks including Taiwanese institutions and major US cancer centers, though specific laboratory structures remain unreported in available materials.

Louis Lukمشاهده پروفایل

مدرس ارشد

• Protein Science
• Biocatalysis
• Medicinal Chemistry
• +۷ مورد دیگر

Dr. Louis Luk is a Senior Lecturer at the School of Chemistry, Cardiff University , leading a research group that bridges chemistry and biology to advance protein science and biocatalysis. His work spans medicinal chemistry, antibacterial peptide research, bioactive candidate design, and biotherapeutic manufacturing. Current roles: Senior Lecturer (2020-present), Lecturer (2019-2020), Cardiff University Research Fellow (2016-2020) Research areas: protein labeling, D-peptide technology, enzyme design, racemic crystallography Research Focus : The group develops scalable and precise protein labeling methods via biocatalysis, discovers peptide binders as medicinal chemistry leads, and synthesizes bifunctional ligands for targeted protein degradation. Techniques include peptide synthesis, molecular cloning, enzyme engineering, and structural biology. Trainees gain skills applicable in academia and industry. Publications (2024-2021) : Recent work explores AEP compartmentalization , genetic code expansion , cyclic enzyme topology , and DHFR dynamics . Studies span racemic crystallography, organocatalysis in protein hosts, and folate modification for targeted delivery. Grants & Collaborations : Principal Investigator for BBSRC (2021-2024), Royal Society (2018-2020), Leverhulme Trust (2017-2020), and Wellcome Seed Trust (2016-2018) projects. Collaborations include Cardiff University researchers (Tsai, Jin) and international institutions (University of British Columbia, ETH Zurich). Teaching & Leadership : Teaches modules on drug discovery, chemical biology, and supramolecular chemistry. Holds leadership roles in RSC committees and Cardiff School of Chemistry ethics/EDI initiatives.

• Socio-Technical Software Engineering
• Developer Attitudes
• Automation in Software Engineering
• +۳ مورد دیگر

Dr. Emily Winter is a Lecturer in Computing and Communications at Lancaster University, part of the School of Computing and Communications (SCC) since 2018. Her research focuses on socio-technical aspects of software engineering, including developer attitudes toward automation, human values in SE, and diversity in computing education. She holds a PhD in Sociology from Lancaster University, an MA in Sociological Research, and a BA in History. Emily has contributed to projects like the Fixie Project (investigating developer attitudes to automated tools) and the Values in Computing initiative. She is a Fellow of AdvanceHE and has received an ESRC 1+3 award for her postgraduate studies. Her external roles include serving as a Reviewer for Information and Software Technology , Workshop Chair for the International Workshop on Genetic Improvement (2022), and Program Committee member for several conferences. Emily teaches the SCC 130 module and actively engages in research addressing gender dynamics in CS education and ethical software design. Key research interests include qualitative methods in SE, developer-centric tool design, and fostering inclusive educational environments. Her work bridges social sciences and computing, emphasizing empirical studies of human-computer interaction in software development. Emily has published widely on topics like automatic program repair, SAST tool usage, and gender representation in CS. Her awards reflect her commitment to pedagogical innovation and social science contributions to computing. She is affiliated with the Security Lancaster research group and is based at InfoLab21.

• Biocatalysis
• Protein Engineering
• Non-Canonical Amino Acids
• +۵ مورد دیگر

Ivana Drienovska is an Assistant Professor in the Department of Chemistry and Pharmaceutical Sciences at the Faculty of Science, Vrije Universiteit Amsterdam . She also holds an affiliation with AIMMS (likely a research institute or program). Her research focuses on biocatalysis, protein engineering, and artificial enzyme design , with a particular emphasis on non-canonical amino acids, genetic code expansion, and functional group diversity in enzymes. She explores applications in sustainable chemistry, enzyme stabilization, and novel catalytic mechanisms. Recent work includes designing protein scaffolds for iminium biocatalysis, stabilizing protein complexes via covalent bicyclization, and incorporating functional secondary amines via genetic code expansion. Her studies often involve structural biology approaches (e.g., crystallography) and synthetic biology techniques. Affiliations : Faculty of Science (VU Amsterdam), AIMMS Courses Taught : Biocatalysis for a Sustainable Future, Bioorganic Chemistry, Concepts in Chemical Biology Key Research Themes : Engineering enzymes for novel functionalities (e.g., unnatural amino acids) Development of artificial metalloenzymes for asymmetric catalysis Structural and biochemical analysis of cold-adapted and extremophilic enzymes Lab/Team : Her group works at the interface of chemical biology, enzymology, and synthetic biology, focusing on creating next-generation biocatalysts for industrial and environmental applications.

• RNA Biology
• Neurodegenerative Diseases
• Neuronal mRNA Translation
• +۵ مورد دیگر

Junjie Guo is an Associate Professor of Neuroscience at Yale School of Medicine, leading the Guo Lab focused on RNA biology and neurological mechanisms. He holds affiliations with the Interdepartmental Neuroscience Program, Center for RNA Science and Medicine, and Wu Tsai Institute. Education : B.A. in Biology (Peking University, 2006), Ph.D. in Neuroscience (Johns Hopkins University, 2011), Postdoctoral Fellow at Whitehead Institute/MIT (2017). Research Interests : Investigates RNA dysregulation in neurodegenerative diseases (e.g., ALS/FTD), noncanonical mRNA translation in neuronal development, and spatial/temporal regulation of neuronal mRNA transport and local translation. Utilizes genomic, molecular, and computational approaches in stem cells, neuronal models, and mouse models. Recent Article Trends : Focuses on SARS-CoV-2 replication mechanisms, RNA structural biology (e.g., G-quadruplexes and tandem repeats), and translational control pathways. Highlights include CRISPR-based screens for viral dependency factors and discovery of alternative translation initiation roles in synaptic organizers. Awards : McKnight Neurobiology of Brain Disorders Award (2023), NYSCF-Robertson Neuroscience Investigator (2021), NIH New Innovator Award (2018), and multiple fellowships from the Klingenstein-Simons and Damon Runyon Foundations. Advising & Grants : Mentors postdocs (e.g., Zhen Lei), graduate students (e.g., Ata Isiktas), and others. Leads NIH-funded projects on RNA biology and neurological disorders. Collaborates with researchers like Marina Picciotto and Craig Wilen. Labs/Teams : Directs the Guo Lab, part of the Yale Neuroscience community. Engages in interdisciplinary initiatives through the Wu Tsai Institute and Center for RNA Science and Medicine.

Jun Liuمشاهده پروفایل

استاد

• Bioinformatics
• Statistical Genetics
• Bayesian Methods
• +۳ مورد دیگر

Jun Liu is a Professor in the Department of Statistics at Harvard University, renowned for his contributions to computational statistics, bioinformatics, and Bayesian methods. He leads research in statistical genetics, genomic data analysis, and algorithm development for biological systems. His work integrates advanced statistical theory with computational tools, such as the Gibbs Motif Sampler and Bayesian Aligner, widely used in bioinformatics. Research interests include Monte Carlo methods, statistical genetics, and machine learning applications in biology. He has developed influential software tools like BPPS, MDScan, and CLIC, addressing problems in motif discovery, genomic sequence analysis, and pathway expansion. Liu’s interdisciplinary approach bridges statistics and computational biology, with applications in cancer genomics, immune repertoire analysis, and evolutionary biology. Notable recognition includes fellowships from the American Statistical Association, Institute of Mathematical Statistics, and International Society for Bayesian Analysis. He advises numerous Ph.D. students and postdoctoral researchers, many of whom hold academic and industry positions globally. His lab collaborates internationally, organizing workshops on Monte Carlo methods and statistical forums in China. Liu’s publications span statistical methodology, computational biology, and genetics, with recent work on genomic element evolution, immune cell profiling, and algorithmic advancements in high-dimensional data analysis. He emphasizes inverse modeling and Bayesian approaches to tackle complex biological questions.

• Protein Engineering
• Synthetic Biology
• Bioprocess Technology
• +۳ مورد دیگر

Birgit Wiltschi is a researcher at the Institute of Bioprocess Science and Engineering within the University of Natural Resources and Life Sciences, Vienna (BOKU) . Her work focuses on protein engineering, non-canonical amino acid incorporation, and bioprocess optimization for therapeutic and industrial applications. Academic Affiliation : BOKU, Institute of Bioprocess Science and Engineering Research Themes : Protein functionalization, bioorthogonal chemistry, enzyme engineering, synthetic biology, and bioproduction systems Recent publication trends highlight her expertise in: Site-specific non-canonical amino acid incorporation Chemoselective protein modification techniques Development of "clickable" therapeutic proteins Lectin engineering for biomedical applications Optimization of microbial bioproduction systems Doctoral Thesis Supervision : Hanaee A: Development of methods for in vitro quantification of proteolysis in E. coli systems (2024)

Oscar Kuipersمشاهده پروفایل

استاد

• Molecular Genetics
• Antimicrobial Peptides
• Prokaryote Biology
• +۷ مورد دیگر

Oscar Kuipers is Professor of Molecular Genetics of Prokaryotes at the University of Groningen, affiliated with the Department of Molecular Genetics within the Groningen Biomolecular Sciences and Biotechnology Institute. His research focuses on prokaryotes—microorganisms without nuclei such as bacteria and cyanobacteria—and the molecular genetic mechanisms governing their functions and interactions. Kuipers studied Biology at Utrecht University, where he also earned his PhD in Biochemistry in 1990. Following his doctoral studies, he worked at NIZO Food Research in Ede and the Wageningen Centre for Food Sciences before joining the University of Groningen. His research interests center on antimicrobial peptides, particularly lanthipeptides like nisin, and their applications in combating antibiotic-resistant bacteria. Kuipers investigates gene regulation, peptide engineering, and the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs). His work bridges fundamental molecular genetics with practical applications in biotechnology and medicine, with a strong emphasis on developing novel antimicrobial strategies against drug-resistant pathogens. Analysis of Kuipers' recent publications reveals a consistent focus on peptide engineering, particularly modifications to nisin and related antimicrobial compounds. His research spans structural modifications to enhance stability and specificity, exploration of novel lanthipeptides from diverse bacterial sources, and investigation of mechanisms by which these compounds interact with bacterial pathogens. A significant portion of his recent work addresses the growing crisis of antibiotic resistance through innovative approaches to peptide-based antimicrobials. Simon Stevin Master Award (2011) with €500,000 research grant Elected member of the Royal Netherlands Academy of Arts and Sciences (KNAW) (2011) €1 million EU grant for synthetic peptides development, particularly for new antibiotics (2013) NWO subsidy for developing microscopic techniques to study intracellular processes (2012) Kuipers actively supervises the University of Groningen student team in the international iGEM competition, which achieved world champion status in 2012 with a biological detection system for meat freshness. He is also co-founder and director of the Centre for Sustainable Antimicrobials (CeSAM), a collaborative initiative between the University of Groningen and University Medical Center Groningen focused on breaking down disciplinary boundaries to accelerate the development of new antibiotics. His laboratory work centers on the Groningen Biomolecular Sciences and Biotechnology Institute, where his team employs advanced techniques in genetic engineering, peptide synthesis, and microbiological analysis to develop and characterize novel antimicrobial compounds. The research environment fosters interdisciplinary collaboration between microbiologists, biochemists, and biotechnologists working toward the common goal of addressing antimicrobial resistance.

Eric V. Anslynمشاهده پروفایل

استاد

• Physical Organic Chemistry
• Supramolecular Chemistry
• Chemical Sensing
• +۳ مورد دیگر

Eric V. Anslyn is Professor of Chemistry at The University of Texas at Austin and Co-Leader of Interdisciplinary Research Group 1 (IRG 1) within the Materials Research Science and Engineering Center (MRSEC). His research program bridges physical organic chemistry, supramolecular systems, and materials science with significant translational impact. His educational trajectory includes: BS in Chemistry from California State University Northridge (1982) PhD in Organic Chemistry from Caltech under Robert Grubbs (1987) NSF Postdoctoral Fellowship at Columbia University with Ronald Breslow (1989) Anslyn's group pioneers chemical sensing methodologies including rapid enantiomeric excess screening and differential sensor arrays for complex mixtures. Recent breakthroughs involve orthogonal reversible covalent bonding systems enabling simultaneous reactions in solution for applications in sequence-defined polymers, self-replicating oligomers, and nanocrystal assemblies. Their work integrates photophysics and mechanistic insights to solve real-world analytical challenges. Major recognitions include: James Flack Norris Award (ACS) Izatt-Christensen Award Czarnik Award Arthur C. Cope Scholar Award HHMI Professorship Texas Regents Teaching Award He currently mentors 13 PhD students across multiple labs (Anslyn, Ellington, Milliron) and 4 postdoctoral researchers, emphasizing an inclusive lab culture that values diversity as essential for scientific creativity. His MRSEC leadership and HHMI funding support collaborative projects in tunable orthogonal reversible covalent (TORC) chemistry and genetic code expansion. The Anslyn Research Group maintains a rigorously inclusive environment committed to cultural, ethnic, and social diversity, with explicit policies ensuring all members' identities do not impede their scientific development. Current projects focus on DNA-compatible TORC chemistry, nanocrystal assembly dynamics, and high-throughput reaction screening platforms.

Paul Jaschkeمشاهده پروفایل

مدرس ارشد

• Synthetic Biology
• Molecular Biology
• Genome Engineering
• +۷ مورد دیگر

Paul Jaschke is a Senior Lecturer in Synthetic Biology at Macquarie University's School of Natural Sciences, affiliated with the Centre of Excellence in Synthetic Biology. He holds a PhD from the University of British Columbia and completed postdoctoral research at Stanford University. His work focuses on bacteriophage engineering for antimicrobial therapies, overlapping genes, and genetic code expansion to combat antibiotic resistance. Education: PhD in Microbiology and Immunology, University of British Columbia NSERC-funded Postdoctoral Fellowship, Stanford University Research Interests: Engineering bacteriophages (T4, T7) for targeted therapy against uropathogenic E. coli Functional roles of overlapping genes in genome evolution Designing synthetic genetic codes for biocontainment and orthogonal translation systems Recent Article Trends: Recent publications emphasize phage-based antimicrobial strategies, synthetic gene design, and viral-host interactions in chemotrophic environments. Key themes include biocontainment systems, host response mechanisms, and modular genome engineering. Awards: People's Choice Award – BioInnovation Initiative Conference (2024) Inter-Departmental Collaboration Award (2022) Advising & Grants: Supervised 9 MRes and 8 PhD students. Active in projects like the International Genetically Engineered Machine (iGEM) Competition and phage therapy development. Lab alumni work at institutions like Harvard Medical School and companies like EnGeneic. Labs/Teams: Leads a research group within the School of Natural Sciences, collaborating with the Centre of Excellence in Synthetic Biology on interdisciplinary projects.

Julea Buttمشاهده پروفایل

استاد

• Biophysical Chemistry
• Microbial Electron Transfer
• Photocatalysis
• +۳ مورد دیگر

Professor Julea Butt is a leading academic in Biophysical Chemistry at the University of East Anglia’s School of Biological Sciences. She specializes in microbial electron transfer mechanisms, biohybrid materials, and photocatalytic systems. Her research focuses on engineering proteins like multiheme cytochromes for applications in sustainable energy and environmental biotechnology. Member of multiple research centers including the Centre for Molecular and Structural Biochemistry and the Wolfson Centre for Advanced Environmental Microbiology. Expertise spans protein structure-function relationships, nanomaterial integration with biological systems, and light-driven catalytic processes. Research interests include: Design of bioelectronic interfaces for solar fuels production Electron transport in bacterial outer membrane proteins Development of semi-artificial photosynthetic systems Mechanistic studies of cytochrome-mediated redox reactions Recent work highlights include: Engineering bespoke biomolecular wires for transmembrane electron transfer Photocatalytic nitrous oxide removal using liposomal microreactors Genetic code expansion for protein functionalization in Shewanella Her lab collaborates on projects involving microbial electron transfer, biohybrid nanomaterials, and sustainable biocatalytic systems. She is actively supervising PhD students in these areas and has published over 130 peer-reviewed articles.

• Synthetic Biology
• Photosynthetic Engineering
• Directed Evolution
• +۴ مورد دیگر

Angad Mehta is a Professor in the Department of Bioengineering at the University of Illinois Urbana-Champaign (UIUC), affiliated with the Grainger College of Engineering. His research focuses on synthetic biology, photosynthetic engineering, and directed evolution, with a particular emphasis on creating artificial endosymbiotic systems and advancing genome engineering techniques. He explores topics such as non-canonical amino acid integration, metabolic pathway design, and evolutionary mechanisms in microbial systems. His work spans foundational studies in bioenergetics and chloroplast function to applied areas like bioenergy production and antiviral strategies. Notable contributions include pioneering efforts in engineering synthetic yeast endosymbionts and developing virus-free directed evolution platforms using somatic hypermutation. He was awarded the Sloan Research Fellowship for his innovative contributions to synthetic biology. Dr. Mehta’s research also addresses fundamental questions in cofactor biosynthesis, such as vitamin B12 and molybdopterin pathways, combining enzymology with synthetic tools. His lab integrates computational modeling, genetic engineering, and biochemical analysis to design novel biological systems with potential applications in healthcare and sustainable biotechnology.