معرفی
Paul Jaschke is a Senior Lecturer in Synthetic Biology at Macquarie University's School of Natural Sciences, affiliated with the Centre of Excellence in Synthetic Biology. He holds a PhD from the University of British Columbia and completed postdoctoral research at Stanford University. His work focuses on bacteriophage engineering for antimicrobial therapies, overlapping genes, and genetic code expansion to combat antibiotic resistance.
Education:
- PhD in Microbiology and Immunology, University of British Columbia
- NSERC-funded Postdoctoral Fellowship, Stanford University
Research Interests:
- Engineering bacteriophages (T4, T7) for targeted therapy against uropathogenic E. coli
- Functional roles of overlapping genes in genome evolution
- Designing synthetic genetic codes for biocontainment and orthogonal translation systems
Recent Article Trends: Recent publications emphasize phage-based antimicrobial strategies, synthetic gene design, and viral-host interactions in chemotrophic environments. Key themes include biocontainment systems, host response mechanisms, and modular genome engineering.
Awards:
- People's Choice Award – BioInnovation Initiative Conference (2024)
- Inter-Departmental Collaboration Award (2022)
Advising & Grants: Supervised 9 MRes and 8 PhD students. Active in projects like the International Genetically Engineered Machine (iGEM) Competition and phage therapy development. Lab alumni work at institutions like Harvard Medical School and companies like EnGeneic.
Labs/Teams: Leads a research group within the School of Natural Sciences, collaborating with the Centre of Excellence in Synthetic Biology on interdisciplinary projects.
