جستجوی استاد راهنمای دانشگاهی

Drew Endyمشاهده پروفایل

دانشیار

• Synthetic Biology
• Bioengineering
• Biotechnology
• +۵ مورد دیگر

Roles and Affiliations: Drew Endy is an Associate Professor of Bioengineering at Stanford University and holds courtesy Senior Fellow positions at the Hoover Institution and the Freeman Spogli Institute for International Studies. He is also a member of Bio-X and currently chairs the Committee on Undergraduate Admissions & Financial Aid. Endy co-directs degree programs at the d.school and serves on multiple administrative and advisory boards, including the Defense Innovation Board and WHO's Variola Virus Research Committee. Education: PhD in Biotechnology & Biochemical Engineering (Dartmouth, 1998), MS in Environmental Engineering (Lehigh, 1994), BS in Civil Engineering (Lehigh, 1992). Research Interests: Endy's work focuses on synthetic biology, including foundational standards for bio-measurements, whole-cell modeling, and applications in unconventional organisms (e.g., wood fungi, skin microbes). He explores genome recoding and biosecurity strategies, while advocating for ethical biotechnology use in conservation and public policy. Recent Article Trends: Recent publications span microbial response to environmental signals, tRNA engineering, colloidal physics in cellular processes, and synthetic biology's role in biodiversity conservation. These studies highlight interdisciplinary approaches to biotechnology innovation and ethical governance. Awards: Honors include the 2017 Honorary Doctorate from TU Delft, 2009 Esquire's 75 Most Influential People, and multiple fellowships recognizing his contributions to bioengineering and policy. Advising & Grants: Endy advises numerous graduate students in bioengineering and public policy. His lab collaborates on projects funded by Stanford's Data Science Initiative and federal agencies, focusing on safety, ethics, and biotechnological applications. Labs & Teams: Leads the Endy Lab at Stanford, emphasizing open science and community standards. Collaborates with iGEM, BioBricks Foundation, and other initiatives to advance synthetic biology education and global research.

Christian Hackenbergerمشاهده پروفایل

استاد

• Biomolecule Modification
• Chemical Biology
• Bioconjugation Reactions
• +۳ مورد دیگر

Christian Hackenberger is a Leibniz-Humboldt Professor of Chemical Biology at Humboldt University and Head of the Chemical Biology II Department at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) . His research centers on synthetic methodology development for natural protein modifications, with applications in biomedicine and drug delivery systems like antibody-drug conjugates (ADCs). Education: University of Freiburg RWTH Aachen University of Wisconsin/Madison (USA) The Hackenberger Group focuses on creating chemoselective bioconjugation reactions to study functional consequences of protein modifications and develop pharmaceutical applications. Their work spans organic synthesis, biochemistry, and biophysics, with a particular emphasis on Staudinger-phosphite/phosphonite reactions and cell-penetrating peptides (CPPs). Recent publications highlight advancements in ethynyl-phosphonamidate peptides for protein delivery, fluorogenic glycan labeling for cell surface imaging, and hydrophilic electrophiles for ADCs . Collaborative efforts with Tubulis GmbH, a company he founded, focus on cancer therapeutics. Scientific Awards: Max Bergmann Medal 2024 Hackenberger actively mentors 13 PhD students and PostDocs , with projects covering topics from tau protein nanobodies to asymmetric organocatalysis . Grants include funding from the German Research Foundation (DFG) , BMBF , and the European Union's Horizon MSCA program .

• Virology
• Flavivirus
• Mosquito-borne Viruses
• +۵ مورد دیگر

Jelke Fros is an Assistant Professor at Wageningen University & Research, specializing in virology and mosquito-borne viral interactions. His research focuses on flaviviruses (e.g., West Nile, Zika, Chikungunya), RNA interference mechanisms, and antiviral protein dynamics. Research Outputs: Over 33 publications, including key contributions to understanding viral genome evolution, xenobiology, and neuroinflammatory impacts of Japanese encephalitis virus. Projects: Co-supervises PhD candidates in studies on arthropod-borne virus transmission, single-cell resolution analysis, and synthetic virology for genetic code expansion. Awards: Recipient of the 2020 Beijerinck Prize for virology research. Collaborations: Active in interdisciplinary networks exploring host immunity evasion, antiviral protein engineering, and mosquito-virus co-infection dynamics. Research Trends: His recent work emphasizes RNA interference in mosquito cell lines DNA methylation effects on blood-brain barrier permeability Evolutionary virology Antiviral protein modulation (e.g., ZAP) Synthetic biology applications in virology Co-infection dynamics in Culex pipiens mosquitoes Scientific Awards Beijerinck Prize (2020)

• Molecular Biology
• Biochemistry
• Genetics
• +۴ مورد دیگر

Dr. Sergey Melnikov is a researcher at Newcastle University, focusing on molecular biology, structural biology, and evolutionary biology, with particular expertise in ribosome structure, protein synthesis, and genetic code expansion. His work spans bacterial, archaeal, and eukaryotic systems, exploring how ribosomal proteins and tRNAs adapt across organisms. Key research areas: Ribosome heterogeneity, translation fidelity, genome decay, and synthetic biology Collaborations: Robert Hirt, Arnaud Basle, Karla Helena Bueno, and others Publications highlight structural insights into ribosomal proteins, error-prone translation in parasites, and engineering of aminoacyl-tRNA synthetases. Recent studies address natural variation in ribosomal drug-binding sites and hibernation factors in bacterial survival.

Joshua D Wytheمشاهده پروفایل

دانشیار

• Cardiovascular Biology
• Cerebrovascular Pathologies
• Developmental Biology
• +۱۲ مورد دیگر

Joshua D. Wythe is an Associate Professor in the Department of Cell and Developmental Biology at the University of Virginia School of Medicine. His research focuses on the molecular and genetic mechanisms underlying cardiovascular development and cerebrovascular pathologies, with a particular emphasis on endothelial cell differentiation and brain vascular diseases such as arteriovenous malformations and glioblastoma. He leads the Wythe Lab, which utilizes zebrafish and mouse models combined with bioinformatics, functional genomics, and 3D imaging to investigate blood vessel formation and dysfunction. BA in History, Miami University BS in Botany, Miami University PhD in Oncological Sciences / Cardiovascular Development, University of Utah School of Medicine Postdoctoral Fellowship in Cardiovascular Development and Disease, University of California, San Francisco Dr. Wythe's research interests span cardiovascular biology, developmental biology, transcriptional regulation, and translational science. His lab investigates how transcriptional networks govern endothelial plasticity, the role of RAS/MEK/ERK signaling in brain arteriovenous malformations, and novel therapeutic targets in glioblastoma. The work integrates molecular genetics, imaging, and bioinformatics to understand both normal vascular development and pathological conditions. The recent publications reflect a strong trend in vascular development, disease modeling, and technological innovation. Key themes include transcriptional control of endothelial identity, signaling pathways in vascular malformations, and advanced imaging techniques for 3D tissue visualization. The research spans from basic developmental mechanisms to translational applications in brain cancers and cerebrovascular disorders. Dr. Wythe actively mentors graduate students, postdoctoral fellows, and undergraduates, fostering a collaborative and interdisciplinary research environment. His lab is currently recruiting researchers with expertise in developmental biology, genomics, bioinformatics, and imaging. Funding supports multiple projects aimed at uncovering transcriptional regulators essential for cardiovascular function and disease. The Wythe Lab is equipped to conduct cutting-edge research using genetically modified animal models, single-cell analyses, and advanced microscopy. The team develops and shares resources such as FishNET for zebrafish colony management and EZ Clear for tissue clearing, contributing to the broader scientific community.

• Computer Science
• Networking
• Quality of Experience (QoE)
• +۵ مورد دیگر

Brecht Vermeulen is a Postdoctoral Researcher at Ghent University's Faculty of Engineering and Architecture, Department of Information Technology. He works within the Internet Technology and Data Science Lab, focusing on networking, video quality assessment, and energy-efficient systems. Research Areas: Quality of Experience (QoE), Dynamic Spectrum Sharing, Video Coding, Interoperability Testing, Federated Experimentation. Key Collaborations: IMEC, FIRE initiative, EU-US/South Korea partnerships. Research Focus: Vermeulen's work spans scalable video coding, distributed CORBA monitoring, and energy efficiency in telecommunications. He applies genetic programming to video quality metrics and explores AI-driven radio systems for spectrum sharing. Publication Trends: His recent articles address zero vulnerability computing hypotheses, healthcare robotics during pandemics, and federated testbed architectures. Earlier works focus on QoE for video, thin client power efficiency, and tunnel setup mechanisms.

• Intellectual Property Law
• International Law
• Patent Law
• +۷ مورد دیگر

Rochelle Cooper Dreyfuss is the Pauline Newman Professor of Law at New York University School of Law, where she has taught since 1983. She specializes in intellectual property law, focusing on patent, copyright, and trademark issues, and has held visiting positions at institutions including Cambridge University as the Arthur Goodhart Visiting Professor in Legal Science (2019-20). Her research explores global IP governance, TRIPS Agreement dynamics, innovation policy, and the intersection of intellectual property with health and technology. She has authored influential books like *Intellectual Property: Cases and Materials* and contributed to projects such as the American Law Institute’s Principles on Transnational IP Disputes. Her work addresses challenges like genetic patenting, access to medicines, and the balance between wealth creation and public health. Dreyfuss has advised international organizations and served on editorial boards of leading journals, including *The Journal of World Intellectual Property*. She is also director of NYU’s Engelberg Center on Innovative Law & Policy.

Oscar P Kuipersمشاهده پروفایل

استاد

• Microbiology
• Molecular Genetics
• Biotechnology
• +۳ مورد دیگر

Oscar P Kuipers is a Professor at the University of Groningen, affiliated with the Faculty of Science and Engineering and the Department of Molecular Genetics. He holds leadership roles as Head of Molecular Genetics and Scientific Director of CeSAM (Center for Sustainable AntiMicrobials). His research focuses on molecular genetics, microbiology, and biotechnology, particularly in antimicrobial peptides, microbial signaling, and genetic engineering. Key activities include advising on academic integrity and scientific roles at Omnicin Therapeutics and the Netherlands Antibiotic Development Platform. Research interests emphasize the design and biosynthesis of antimicrobial agents, genetic code expansion for controlled metabolite production, and microbiome interactions impacting health. Recent work explores engineered peptides like nisin analogues and lanthipeptides from Clostridium species. Collaborations span drug development, microbial ecology, and metabolic disease mechanisms. He has contributed to over 500 publications, with recent articles addressing peptide engineering, bacterial regulatory circuits, and ecosystem-based natural product discovery. His work bridges fundamental research and applied solutions for antibiotic resistance and sustainable biotechnology.

Wenshe Ray Liuمشاهده پروفایل

استاد

• Epigenetic Chromatin Regulation
• Histone Modifications
• Therapeutic Drug Development
• +۳ مورد دیگر

Wenshe Ray Liu, PhD is a distinguished academic and researcher at Texas A&M University, holding the titles of Presidential Impact Fellow and Gradipore Endowed Chair in Chemistry . He serves as a Professor in the Department of Chemistry and Biochemistry and Biophysics, with dual appointments in both disciplines. His research spans epigenetic chromatin regulation and drug development targeting epigenetic proteins. Education : B.S. in Chemistry, Peking University (2000) PhD in Chemistry, University of California, Davis (2005) Postdoctoral Researcher at The Scripps Research Institute (2005–2007) Research Interests : Epigenetic regulation via histone posttranslational modifications (PTMs) Development of therapeutics targeting chromatin-modifying enzymes (SIRT1-3, HDACs, LSD1-2, ENL, BRD9) Chemical biology tools for chromatin assembly and analysis Phage display technologies for peptide library diversification His lab operates two core units: a biological unit focusing on chromatin structure-function studies and a chemical unit developing novel inhibitors and drug candidates. Grants & Awards : Presidential Impact Fellow (2018) ACS Chemical Biology Most Prolific Author (2017) NSF Career Award (2012) Molecular BioSystems Emerging Investigator (2010) Lab & Collaborations : Leverages cryo-EM, proteomics, and synthetic chemistry for structural and functional studies Active in SARS-CoV-2 main protease inhibitor discovery Develops genetic code expansion tools for site-specific protein modification

Richard Obexerمشاهده پروفایل

پژوهشگر ارشد

• Biochemistry
• Molecular Biology
• Enzyme Engineering
• +۳ مورد دیگر

Dr. Richard Obexer is a BBSRC Discovery Fellow in Chemical Biology and Biological Chemistry. His research contributes to UN Sustainable Development Goals through innovations in enzyme engineering and synthetic biology. Active in enzyme design and non-canonical amino acid applications Key collaborations with institutions like Cold Spring Harbor Laboratory Published in high-impact journals: Nature Communications, Nature Chemistry, Science Research Focus: Specializing in creating novel enzymatic pathways and synthetic protein systems. His work explores: Non-canonical nucleophile integration in enzyme design Membraneless organelle assembly from de novo proteins Phase-separating polypeptide engineering Therapeutic oligonucleotide production via enzyme cascades Genetic code expansion for functional protein design Scientific Contributions: Recent publications demonstrate breakthroughs in catalytic mechanism innovation and biomolecular condensate engineering. Nature Communications (2024): Designed enzyme with non-canonical nucleophile Nature Chemistry (2024): Membraneless organelle assembly using synthetic proteins Science (2023): Scalable oligonucleotide production system Awards: Recipient of the prestigious BBSRC Discovery Fellowship supporting his innovative research.

John Pezackiمشاهده پروفایل

استاد

• Host-Pathogen Interactions
• Biochemistry
• Microbiology
• +۱۰ مورد دیگر

Dr. John Pezacki is a Professor in the Department of Chemistry and Biomolecular Sciences at the University of Ottawa, cross-appointed to the Faculty of Medicine. His research focuses on developing chemical and biophysical tools to study host-pathogen interactions, with a particular emphasis on human viruses like hepatitis viruses, Dengue, and SARS-CoV-2. BSc, University of Toronto PhD, McMaster University His work integrates activity-based profiling , bioorthogonal chemistry , non-coding RNA screening , and expanded genetic code technologies to explore new therapeutic targets and vaccine strategies. He operates state-of-the-art labs for chemistry, microbiology, and cell biology, collaborating with the university’s core facilities. Recent publications highlight his contributions to understanding microRNA regulation in viral infections, machine learning applications in chemical reactions, and bioorthogonal methodologies for molecular labeling. His research has been recognized with awards such as the Armand-Frappier Outstanding Student Award and the Canadian Society of Microbiologists’ Armand-Frappier Gold Medal . john.Pezacki@uOttawa.ca The Pezacki Lab fosters a multidisciplinary environment for students and postdoctoral fellows, emphasizing innovation in chemical biology and virology.

Loli Molina Jiménezمشاهده پروفایل

استاد

• Genetics
• Developmental Biology
• Stem Cell Research
• +۶ مورد دیگر

Maria Dolores (Loli) Molina Jiménez serves as a Full Professor in the Department of Bioengineering at IQS School of Engineering, Universitat Ramon Llull. Her academic career spans prestigious institutions including the University of Barcelona, Institut de Biologie Valrose in France, and Observatoire Oceanographique de Villefranche. She holds a PhD in Genetics from the University of Barcelona (2011) and has established herself as a leading researcher in developmental biology using planarian and sea urchin models. PhD in Genetics, University of Barcelona (2011) Diploma of Advanced Studies (DEA) in Genetics and Development, University of Barcelona (2007) Degree in Biochemistry, University of Barcelona (2010) Degree in Biology, University of Barcelona (2005) Professor Molina Jiménez's research focuses on genetic regulation of stem cell homeostasis and differentiation during planarian regeneration, with applications to cancer biology and environmental monitoring. Her work bridges molecular biology, developmental genetics, and regenerative medicine, utilizing advanced techniques including in vivo imaging, molecular biology, gene expression analysis, immunohistochemistry, and microscopy. She has made significant contributions to understanding LIM-HD transcription factors in axial patterning and cell identity specification in planarians, as well as TGF-β signaling in sea urchin embryonic development. Her recent publications demonstrate expertise across developmental biology, genomics, and environmental toxicology, with notable work on sea urchin genome evolution, planarian regeneration mechanisms, and the developmental toxicity of plastic pollutants. Her research has attracted significant attention, with multiple articles picked up by news outlets and cited across scientific platforms. Beatriu de Pinós Fellowship Marie Sklodowska-Curie COFUND Postdoctoral Fellowship EMBO Long-Term Postdoctoral Fellowship Professor Molina Jiménez has supervised numerous research projects and students, contributing to both the Bachelor's Degree in Biomedical Sciences and the Master's Degree in Bioengineering at IQS. Her laboratory maintains specialized planarian cultures and employs cutting-edge molecular techniques to investigate fundamental questions in regeneration and development. Her collaborative network extends across Europe, with significant contributions to large-scale genomic projects and environmental impact studies.

• Neuroscience
• Molecular Neuroscience
• Advanced Fluorescent Microscopy
• +۶ مورد دیگر

Nevena Stajkovic is a postdoctoral researcher at Forschungszentrum Juelich (IBI-3) since November 2023. She previously held a postdoctoral position at the Hertie Institute for Clinical Brain Research and the Centre for Integrative Neuroscience in Tuebingen, Germany (April-October 2023), and is currently affiliated with RWTH Aachen since October 2023. Her research focuses on neuroelectronic interfaces and advanced imaging techniques. Education: Bachelor’s in Molecular Biology and Physiology (2011-2015), University of Belgrade. Master’s in Neurobiology (2015-2016), University of Belgrade. Ph.D. in Cellular and Molecular Neuroscience (2017-2023), University of Tübingen. Nevena specializes in genetically encoded enhancers for electron microscopy, voltage-gated sodium channels, and biorthogonal click chemistry. Her expertise spans super-resolution microscopy , fluorescent protein tagging , and molecular/cell biology . She previously developed methods to label neuronal proteins and optimize imaging media for advanced microscopy applications. Scientific Awards: Award for the best Master's thesis in Physiology (2016).

Łukasz J Sznajderمشاهده پروفایل

استادیار

• RNA Biology
• Genetic Disorders
• Alternative Splicing
• +۳ مورد دیگر

Łukasz J Sznajder is an Assistant Professor in the Department of Chemistry and Biochemistry at the University of Nevada, Las Vegas , focusing on RNA biology and its role in genetic disorders. His research primarily investigates the molecular mechanisms behind alternative splicing dysregulation in diseases such as myotonic dystrophy. CURRENT ROLE: Assistant Professor AFFILIATION: UNLV Department of Chemistry and Biochemistry CONTACT: lukasz.sznajder@unlv.edu Research Interests revolve around: MBNL protein function in RNA splicing Toxic RNA accumulation in repeat expansion diseases Neurodevelopmental consequences of RNA misprocessing Therapeutic strategies using CRISPR/Cas9 systems Cell-type-specific splicing defects RNA metabolism dynamics in neuromuscular disorders Scientific Trends from Publications (2018-2025) reveal: Central role of MBNL sequestration in RNA mis-splicing Systemic effects of repeat expansions on multiple organs Emerging therapeutic approaches targeting RNA toxicity Intersection of developmental gene regulation and disease Structural context dependency of splicing factors Translational relevance of mouse models in human disease

Jens Rauchمشاهده پروفایل

استادیار

• Cancer Biology
• Melanoma
• Signal Transduction
• +۷ مورد دیگر

Jens Rauch is an Assistant Professor at the School of Biomolecular and Biomedical Science, University College Dublin, and serves as Group Leader at Systems Biology Ireland. His research focuses on understanding drug resistance mechanisms in malignant melanoma, particularly through RAS/RAF/MEK/ERK (MAPK) signaling pathway dynamics and scaffold protein interactions. He employs proteomics, CRISPR/Cas9, and computational modeling to identify network adaptations and develop personalized therapeutic strategies. Research Highlights: Investigating eIF4F complex's role in MAPK pathway regulation Decoding RAF kinase dimerization mechanisms and drug resistance Developing combination therapies for BRAF/NRAS mutant melanomas Exploring spatial regulation of signaling pathways via subcellular localization Professional Involvement: Member of multiple scientific committees (Systems Biology Ireland, BSc Biomedical Health Committee) Active participant in Society for Melanoma Research and European Association for Cancer Research Recipient of research grants including SBBS MSc funding and Biotech Research Projects