Sergey Melnikov

Dr. Sergey Melnikov is a researcher at Newcastle University, focusing on molecular biology, structural biology, and evolutionary biology, with particular expertise in ribosome structure, protein synthesis, and genetic code expansion. His work spans bacterial, archaeal, and eukaryotic systems, exploring how ribosomal proteins and tRNAs adapt across organisms.

• Key research areas: Ribosome heterogeneity, translation fidelity, genome decay, and synthetic biology
• Collaborations: Robert Hirt, Arnaud Basle, Karla Helena Bueno, and others

Publications highlight structural insights into ribosomal proteins, error-prone translation in parasites, and engineering of aminoacyl-tRNA synthetases. Recent studies address natural variation in ribosomal drug-binding sites and hibernation factors in bacterial survival.