جست‌وجوی استاد و پژوهشگر

Brian Cherringtonمشاهده پروفایل

دانشیار

• Reproductive Physiology
• Immunology
• Molecular Biology
• +۳ مورد دیگر

Brian Cherrington is an Associate Professor in the Department of Zoology and Physiology at the University of Wyoming, part of the College of Agriculture, Life Sciences, and Natural Resources. His research focuses on the role of peptidylarginine deiminase (PAD) enzymes in female reproduction and associated diseases, including their involvement in rheumatoid arthritis, reproductive cancers, and hormonal regulation. He teaches courses such as Human Systems Physiology and Mammalian Genomics. Education: B.A., Washington University, 1996 M.S., Colorado State University, 2001 Ph.D., Colorado State University, 2005 Research Interests: Citrullination and PAD enzymes in reproductive tissues Role of PADs in autoimmune diseases like rheumatoid arthritis Epigenetic regulation of miRNA programs during lactation Mechanisms of gonadotrope cell plasticity during ovulation Lab Projects: Investigating PADs and anti-citrullinated protein antibodies in the cervicovaginal mucosa. Defining PAD's role in the pre-ovulatory LH surge. Epigenetic regulation of lactotrope cell expansion during pregnancy. Teaching: Human Systems Physiology (ZOO 3115) Mammalian Genomics (ZOO 4735/5735) The Art and History of Medicine (HP 4152, J-Term study abroad) Labs/Teams: Cherrington Lab at the University of Wyoming, focusing on molecular and cellular mechanisms of female reproduction and disease. The lab includes PhD student Ari Tourtellot and collaborates with experts in immunology, endocrinology, and cancer biology.

• Gut Microbiology
• Rumen Metabolism
• Preharvest Food Safety
• +۶ مورد دیگر

T.G. Nagaraja , University Distinguished Professor of Microbiology at Kansas State University's College of Veterinary Medicine, has dedicated his career to Gut Microbiology with a focus on Rumen Metabolism and Preharvest Food Safety . His research addresses the role of gut microbes in cattle health, particularly Shiga toxin-producing E. coli (STEC) , Salmonella , and Antimicrobial Resistance in beef production systems. BVSc (1970), MVSc (1972) in Veterinary Microbiology from Mysore Veterinary College PhD (1977) in Microbiology from Kansas State University Nagaraja's work spans basic and applied studies on ruminal acidosis and liver abscesses , collaborating with experts in Epidemiology, Molecular Biology, and Ruminant Nutrition. His lab develops interventions to mitigate foodborne pathogens through dietary modifications and vaccine strategies. Key publications highlight advancements in STEC detection (2018), comparative genomics of non-O157 serogroups (2017), and multiplex PCR assays (2015). Recent articles focus on antimicrobial resistance mechanisms and vaccine efficacy against liver abscesses. Scientific contributions include six US patents for Fusobacterium necrophorum vaccines and detection methods. Teaching responsibilities include Veterinary Bacteriology , Rumen Metabolism , and Rumen Microbiology graduate courses.

Leighton Coreمشاهده پروفایل

دانشیار

• RNA transcription
• Gene expression regulation
• Genomic techniques
• +۴ مورد دیگر

Leighton Core is an Associate Professor in the Department of Molecular and Cell Biology and Genetics and Genomics at the University of Connecticut. His research focuses on understanding how RNA transcription and processing influence cellular states during development and disease progression. Using genomic techniques and bioinformatics, his lab identifies transcriptional signatures of cell types and elucidates fundamental transcription mechanisms. Education: PhD in Molecular Biology and Genetics, Cornell University Postdoctoral Training: Molecular Biology and Genetics, Cornell University Bachelor’s Degree in Biology, Boston College Research Interests: Core’s lab investigates RNA transcription dynamics, particularly how changes in transcription and processing drive cellular responses. Key areas include enhancer activity, paused RNA polymerase II regulation, and the interplay between transcriptional mechanisms and cellular states. Techniques employed include PRO-seq and chromatin run-on sequencing to map transcriptional landscapes. Publications: Recent work highlights contributions to understanding transcriptional regulation in cancer (e.g., glioblastoma), epigenetic mechanisms (e.g., histone acetylation), and novel methodologies like optimized PRO-seq. Over 30 peer-reviewed articles span topics from centromere biology to stem cell differentiation. Labs/Teams: Leads a research group focused on transcriptional genomics, collaborating on projects involving cancer epigenetics and developmental biology.

Yiqiang Zhangمشاهده پروفایل

استادیار

• Cardiovascular Biology
• Stem Cell Biology
• Regenerative Medicine
• +۶ مورد دیگر

Yiqiang Zhang, PhD is an Assistant Professor in the Department of Anatomy, Biochemistry & Physiology at the University of Hawaii John A. Burns School of Medicine, affiliated with the Center for Cardiovascular Research. He holds graduate faculty roles in Developmental and Reproductive Biology (DRB) and Cell and Molecular Biology (CMB). Dr. Zhang earned his B.Sc. in Biology (Zoology) and M.Sc. in Physiology from Sun Yat-sen University (China), followed by a PhD in Biomedical Sciences from the University of Montreal (2006). His postdoctoral training included Johns Hopkins Medicine’s Cardiology Fellowship Program and Cedars-Sinai Medical Center, focusing on developmental cell biology and cardiac electrophysiology. He has held prior roles as a Staff Scientist at City of Hope National Medical Center and Acting Assistant Professor at the University of Washington School of Medicine. His research integrates multi-omics, bioinformatics, and advanced cellular/molecular techniques to study cardiac development, disease mechanisms, and regenerative therapies. Key projects include: epigenetic regulation of cardiomyocyte cell cycle re-entry, single-cell analysis of heart failure mechanisms, and leveraging stem cell models to understand congenital heart defects. His work addresses diabetic cardiomyopathy, arrhythmias, and heart failure through translational approaches. Supported by NIH, American Heart Association, and other funding agencies, his lab seeks to identify novel therapeutic targets for cardiovascular diseases. Dr. Zhang teaches across undergraduate, graduate, and medical programs, emphasizing translational research and clinical education. His contributions span over 60 peer-reviewed publications, including high-impact studies in Cell , Circulation , and Nature journals. Current research emphasizes computational genomics, epigenetic modifiers, and inflammatory pathways in cardiac disorders.

Shelley Adamoمشاهده پروفایل

استاد

• Ecoimmunology
• Parasitic Manipulation of Behavior
• Climate Change Effects on Insects
• +۳ مورد دیگر

Shelley Adamo is a Professor in the Department of Psychology and Neuroscience at Dalhousie University, located in Halifax, Nova Scotia. Her research focuses on the interplay between behavior and physiology in insects, with particular emphasis on ecoimmunology, parasitic manipulation of host behavior, and climate change impacts on arthropods. She uses insect models like Manduca sexta caterpillars and Ixodes ticks to investigate stress response networks, immunological trade-offs, and parasitic behavioral control mechanisms. Adamo holds a BSc from the University of Toronto and a PhD from McGill University. Her lab employs behavioral studies, biochemical assays, and molecular techniques to explore how organisms balance competing physiological demands under environmental challenges. Notable projects include studying how parasitic wasps hijack caterpillar nervous systems and how temperature changes affect tick survival and disease transmission. Teaching responsibilities include courses on neuroethology, cellular neurobiology, and ecological immunology. She has published extensively on topics ranging from insect immune responses to the ecological implications of climate change. Her work bridges behavioral ecology, immunology, and neurobiology to understand adaptive defense systems in invertebrates. Contact details: Life Sciences Centre Room 3324, Halifax, NS B3H 4R2 | Email: Shelley.Adamo@dal.ca | Phone: (902) 494-8853

• Lateral Gene Transfer
• Genomics
• Bacterial Pathogens
• +۳ مورد دیگر

Dr. Julie C. Dunning Hotopp is a Professor in the Department of Microbiology and Immunology at the University of Maryland School of Medicine. She is also a Member of the Institute for Genome Sciences and leads research on bacterial DNA integration into animal genomes, with implications for both evolutionary biology and human health. Primary Appointment : Microbiology and Immunology Additional Affiliation : Institute for Genome Sciences Research Overview : Dr. Dunning Hotopp's groundbreaking work focuses on lateral gene transfer (LGT) between bacteria and animals, notably documenting widespread LGT in invertebrates (Dunning Hotopp et al., 2007 Science ) and investigating bacterial DNA integration into human somatic genomes, particularly in cancer (2013 PLoS Comput Bio ). Her lab explores genomic interactions between pathogens like Wolbachia , Ehrlichia , Anaplasma , and Neisseria meningitidis and their hosts. Scientific Awards : 2010 NIH Director’s New Innovator Award 2010 Leading Women of Maryland (Maryland Daily Record) 2010 Genome Technology Young Investigator 2015 NIH Transformative Research Award Recent Publications examine bacterial integration in Drosophila ananassae , filarial nematodes, and human cancers, alongside developing bioinformatics tools for microbial comparative genomics. Labs & Teams : Her research group at the Institute for Genome Sciences investigates LGT mechanisms and pathogen-host genomics, with projects spanning computational genomics, transcriptomics, and public health implications.

• Conservation Biology
• Herpetology
• Giant Tortoise Ecology
• +۲ مورد دیگر

James Gibbs is a Distinguished Professor in the Department of Environmental Biology at the State University of New York College of Environmental Science and Forestry. He holds a B.S. in Wildlife Management from the University of Maine (1986), M.A. in Biological Sciences from the University of Missouri (1988), and Ph.D. in Forestry & Environmental Studies from Yale University (1995). His research spans conservation biology and herpetology, with significant focus on: Galápagos giant tortoise ecology and conservation Urban-rural evolutionary gradients in mammals Vernal pool conservation thresholds Indigenous ecological knowledge integration Wildlife responses to environmental contamination Recent work explores evolutionary impacts of urbanization on squirrel coat color, conservation thresholds for vernal pool ecosystems, and rewilding effects of giant tortoises on island landscapes. His publications demonstrate strong interdisciplinary approaches combining genetics, stable isotope analysis, and field ecology. Dr. Gibbs advises graduate students including Brayden Nichols and teaches Conservation Biology (EFB 413) and Herpetology (EFB 485). He has led significant restoration initiatives in the Galápagos Islands, including tortoise reintroduction programs that demonstrate ecosystem engineering effects on plant communities.

• Signal Regulated Transcription
• Chromatin and Gene Regulation
• Nuclear Receptors
• +۵ مورد دیگر

W. Lee Kraus, Ph.D. is Professor and Director of the Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center. He holds the Cecil H. and Ida Green Distinguished Chair in Reproductive Biology Sciences and serves as Vice Chair for Basic Sciences in the Department of Obstetrics and Gynecology, Assistant Director for Basic Research at the Simmons Comprehensive Cancer Center, and the inaugural Assistant Dean for Research Development. He is also a member of the Board of Directors of the Endocrine Society (2023-2026). Dr. Kraus earned his Bachelor of Science from Cornell University in 1989, completed his Ph.D. at the University of Illinois, Urbana-Champaign in 1994 under Benita S. Katzenellenbogen, and conducted postdoctoral research at UC San Diego with Jim Kadonaga, supported by NIH and American Cancer Society fellowships. His laboratory investigates signal regulated transcription, chromatin and gene regulation, nuclear receptors, PARPs, and NAD+ metabolism and signaling. The Kraus Lab has pioneered research on ADP-ribosylation mechanisms, revealing how PARP enzymes regulate transcriptional programs in reproduction, development, and cancer. His work has established critical connections between NAD+ metabolism, chromatin modification, and gene expression, with particular focus on hormonal regulation in breast cancer and reproductive tissues. Dr. Kraus has published over 150 original research articles with an h-index of 77 (Google Scholar 2022). His recent work demonstrates increasing sophistication in connecting PARP enzymatic activity with specific transcriptional outcomes across multiple disease contexts, particularly in cancer biology and metabolic regulation. His scientific contributions have been recognized with prestigious awards: Endocrine Society's Richard E. Weitzman Memorial Award (2007) Endocrine Society's Ernst Oppenheimer Award (2014) Cornell University Teaching Excellence Award (2004) Cornell University Research Mentoring Award (2008) Burroughs Wellcome Fund Career Award As a mentor, Dr. Kraus has trained 22 doctoral students, 26 postdocs, and 16 clinical fellows (as of 2022), with most former trainees securing faculty positions or research roles in academia and industry. His research has been continuously supported by major grants from NIH, American Cancer Society, Cancer Prevention and Research Institute of Texas, Endocrine Society, and NSF. The Green Center for Reproductive Biology Sciences under Dr. Kraus's leadership maintains a vibrant research environment focused on basic mechanisms of reproduction, development, and cancer. Beyond academia, he co-founded Ribon Therapeutics and ARase Therapeutics, translating basic discoveries about PARP biology into therapeutic applications, and serves on multiple biotech advisory boards.

Charles Guمشاهده پروفایل

دانشیار

• Genetic Epidemiology
• Statistical Genetics
• Machine Learning in Biomedical Data
• +۵ مورد دیگر

Charles Gu is an Associate Professor of Biostatistics and Genetics at Washington University in St. Louis, affiliated with the Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS), the Institute for Informatics, and the Center for Biostatistics and Data Science (CBDS). His research focuses on genetic epidemiology and statistical genetics, particularly in developing computational methods for analyzing high-dimensional genetic data and studying gene-environment interactions in complex diseases like hypertension, cardiovascular disorders, and metabolic syndromes. Key affiliations include the DBBS programs in Biomedical Informatics, Computational and Systems Biology, and Human and Statistical Genetics. He mentors PhD/MSTP students and collaborates internationally on large-scale genomic studies. Recent work includes studies on clonal hematopoiesis, lipid metabolism, and blood pressure prediction using machine learning. His 164+ publications span genetic association studies, epigenetic research, and multi-omics approaches, with a focus on translating statistical methods to clinical insights. Notable projects involve genomic analyses of atrial fibrillation, coagulation factors, and the impact of lifestyle on genetic traits.

• Antibiotic Resistance
• Infectious Disease Research
• Antibiotic Biochemistry
• +۵ مورد دیگر

Gerard Wright is a distinguished Professor of Biochemistry and Biomedical Sciences at McMaster University's Faculty of Health Sciences. He serves as the Executive Director of the Global Nexus School for Pandemic Prevention & Response and as Scientific Director of the Michael G. DeGroote Institute for Infectious Disease Research, which he founded and previously directed. Dr. Wright holds the prestigious Michael G. DeGroote Chair in Infection and Anti-Infective Research and a Canada Research Chair in Antibiotic Biochemistry. Dr. Wright's research focuses on antibiotic resistance mechanisms, infectious disease, and anti-infective drug discovery. His work spans biochemical characterization of resistance enzymes, discovery of novel antibiotics from microbial natural products, and understanding the environmental resistome. He has pioneered approaches to combat antibiotic resistance through enzyme inhibition and antibiotic adjuvants. His laboratory has made significant contributions to understanding glycopeptide antibiotics, aminoglycoside resistance mechanisms, and metallo-β-lactamase inhibitors like aspergillomarasmine A. His recent publications demonstrate continued leadership in the field, with research spanning novel antibiotic discovery (including lasso peptides and lipopeptaibiotics), antifungal development against pathogens like Candida auris, and innovative approaches to resistome profiling. His work bridges fundamental biochemistry with translational applications for combating drug-resistant infections. Canadian Institutes of Health Research Scientist Medical Research Council of Canada Scholar Killam Research Fellowship recipient Member of the Canadian Academy of Health Sciences Dr. Wright has advised numerous funding panels for agencies in Canada, the US, and Europe, and consults extensively with the pharmaceutical and biotech sectors. His laboratory maintains active collaborations across disciplines, focusing on translating basic research into potential therapeutic strategies against antimicrobial resistance. His work on pandemic preparedness through the Global Nexus School represents a significant contribution to public health infrastructure.

• Industrial Biotechnology
• Metabolic Engineering
• Synthetic Biology
• +۷ مورد دیگر

Professor Patrik Jones is a Visiting Professor in the Department of Life Sciences at Imperial College London, affiliated with multiple research centers including the Centre for Synthetic Biology, Grantham Institute, and Industrial Biotechnology Hub. His work focuses on metabolic engineering, synthetic biology, and biofuel production using cyanobacteria. Key projects include the PHOTOFUEL consortium and the development of C3 Biotechnologies. He has been recognized with the Faculty of Natural Sciences Prize for Excellence in Teaching (2018). Research interests span industrial biotechnology, enzyme design, and systems biology, with a focus on sustainable chemical production. Notable contributions include engineering cyanobacteria for biofuel synthesis and developing novel metabolic pathways. His group has published extensively on cyanobacterial engineering, co-factor optimization, and solar-driven fuel production. Publications highlight advancements in fatty acid production, CO₂ utilization, and propane biosynthesis. Collaborations include work with Arren Bar-Even on synthetic metabolism and Tobias Erb on metabolic engineering strategies. Students under his supervision have contributed to breakthroughs in 1-octanol production and cyanobacterial strain engineering. Awards reflect both research and teaching excellence, emphasizing his dual role as a scientist and educator. The Microbial Metabolic Engineering Group under his leadership explores cutting-edge solutions for renewable energy and environmental sustainability.

• Functional Genomics
• CRISPR Technology
• Stem Cell Research
• +۴ مورد دیگر

Dr. Cesar L. Moreno is a Postdoctoral Research Associate and Dr. John and Anne Chong Genome Editing and Stem Cell Research Fellow at the School of Life and Environmental Sciences, The University of Sydney, with an adjunct appointment as Associate Lecturer at the Kirby Institute, University of New South Wales. His work focuses on developing functional genomic tools for disease modeling using stem cells and mouse models. Education: PhD in Neuroscience from Icahn School of Medicine at Mount Sinai (2015) Postdoctoral training at Gandy Lab and New York Stem Cell Foundation (2015-2017) Research at UQ-StemCARE Centre, University of Queensland (until 2020) Dr. Moreno's research centers on CRISPR-based genetic screens in stem cells to investigate diseases like COVID-19 and biological processes including neural development and ageing. He integrates functional genomic and epigenomic approaches to uncover molecular pathways in neurodegenerative disorders, metabolic diseases, and viral pathologies, with emphasis on translating findings into therapeutic strategies. His 15 most recent publications reveal a strong trajectory in genome editing technologies, stem cell disease modeling, and virology, particularly SARS-CoV-2 research. Key themes include CRISPR screening innovations, Alzheimer's disease mechanisms using iPSC models, metabolic regulation, and neuroinflammation, demonstrating consistent interdisciplinary collaboration. Scientific Awards: Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows F31 (2011-2015) Travel Scholarship for Aging and Diseases of Aging Keystone Symposium, Tokyo, Japan (2012) Dr. Moreno currently supervises two research students on dementia-related projects and secured a 2022 NHMRC Ideas Grant for the "UNIVERSAL NEUROPHOTONIC INTERFACE" project. He serves as a member of the Charles Perkins Centre and leads four major research initiatives spanning CRISPR barcoding, SARS-CoV-2 pathology, circadian rhythms in brain development, and neurophotonic stem cell models.

Tom Brownمشاهده پروفایل

استاد

• Nucleic Acid Chemistry
• CRISPR Technology
• Diagnostic Technologies
• +۵ مورد دیگر

Tom Brown is a Professor of Nucleic Acid Chemistry at the University of Oxford's Department of Chemistry. His research focuses on designing and synthesizing chemically modified DNA and RNA for diagnostic and therapeutic applications, including CRISPR systems for genome editing. He has developed Scorpion primers and HyBeacons, used in personalized medicine and rapid forensic analysis. His work has led to the creation of biotech companies like ATDBio and Primer Design, contributing significantly to COVID-19 diagnostics. Research Interests: Brown's group explores nucleic acid modifications, DNA structure-function relationships, and the application of click chemistry for gene assembly. They use techniques like X-ray crystallography and NMR to study DNA interactions with repair enzymes and mutagenic lesions. Key Contributions: Contributions include rapid mutation identification methods, oligonucleotide delivery platforms, and spherical nucleic acids for stem cell isolation. His work bridges chemistry and medicine, with applications in diagnostics, therapeutics, and biotechnology. Awards: While no specific awards are listed, his impactful research has driven industry collaboration and innovation in nucleic acid-based technologies. Labs/Teams: Leads the Nucleic Acids Research Group and the Brown Group, focusing on interdisciplinary projects in chemistry, biology, and medicine.

• Aptamer Technology
• Optogenetics
• Targeted Therapies
• +۴ مورد دیگر

Prof. Günter Mayer is a Professor at the University of Bonn's Life and Medical Sciences Institute (LIMES) and affiliated with the Faculty of Mathematics and Natural Sciences. His research focuses on aptamer technology, optogenetics, and targeted therapies, aiming to develop molecular tools for precise biological investigation and clinical applications. Key projects include using in vitro selection to engineer nucleic acids for diagnostics/therapeutics and exploring nucleic acid evolution principles to generate novel compounds. His research addresses how aptamers can elucidate biological phenomena, design light-controllable RNA molecules, and create tools for high-precision diagnostics. Notable achievements include developing click-SELEX methods for aptamer selection, optoribogenetic systems for gene regulation, and RNA-based biosensors for metabolic monitoring. Publications emphasize interdisciplinary approaches combining biochemical, molecular, and biophysical techniques. Work spans SARS-CoV-2 aptamer antivirals, immune modulation via T-cell activation, and anti-inflammatory aptamers for hypersensitivity treatment. Collaborations with groups like the NeurotechEU alliance highlight transdisciplinary impact. Research infrastructure includes the Mayer Lab (website: http://www.mayerlab.de/), focusing on translating fundamental nucleic acid science into clinical solutions. Current efforts prioritize precision medicine applications and next-gen diagnostic platforms through systems biology approaches.

Xin Biمشاهده پروفایل

استاد

• Epigenetic regulation of eukaryotic gene expression
• Structural and functional domains of the genome
• Chromatin boundary elements
• +۳ مورد دیگر

Xin Bi is a Professor in the Department of Biology at the University of Rochester, part of the School of Arts & Sciences. His research focuses on epigenetic regulation, chromatin structure, and gene expression in eukaryotes, using the yeast Saccharomyces cerevisiae as a model system. Key interests include silencer function, chromatin barriers, DNA damage repair, and histone acetylation mechanisms. Research Overview: Investigates how silencers initiate transcriptionally silent chromatin formation, including directionality and genomic context effects. Examines barriers that prevent silent chromatin spread into active regions, such as HM loci. Explores histone hypoacetylation's role in gene repression versus chromatin compaction. Studies long-range histone acetylation by targeted histone acetyltransferases. Publications: Over 50 peer-reviewed articles, including recent work on Hmo1's role in DNA damage tolerance (2025) and γH2A's checkpoint signaling (2024). Research spans chromatin remodeling factors, heterochromatin stability, and DNA repair mechanisms. Labs & Teams: Leads a lab focused on chromatin dynamics and epigenetic regulation, mentoring undergraduate researchers. Collaborates with international teams on yeast genetics and chromatin structure.