معرفی
Brian Cherrington is an Associate Professor in the Department of Zoology and Physiology at the University of Wyoming, part of the College of Agriculture, Life Sciences, and Natural Resources. His research focuses on the role of peptidylarginine deiminase (PAD) enzymes in female reproduction and associated diseases, including their involvement in rheumatoid arthritis, reproductive cancers, and hormonal regulation. He teaches courses such as Human Systems Physiology and Mammalian Genomics.
Education:
- B.A., Washington University, 1996
- M.S., Colorado State University, 2001
- Ph.D., Colorado State University, 2005
Research Interests:
- Citrullination and PAD enzymes in reproductive tissues
- Role of PADs in autoimmune diseases like rheumatoid arthritis
- Epigenetic regulation of miRNA programs during lactation
- Mechanisms of gonadotrope cell plasticity during ovulation
Lab Projects:
- Investigating PADs and anti-citrullinated protein antibodies in the cervicovaginal mucosa.
- Defining PAD's role in the pre-ovulatory LH surge.
- Epigenetic regulation of lactotrope cell expansion during pregnancy.
Teaching:
- Human Systems Physiology (ZOO 3115)
- Mammalian Genomics (ZOO 4735/5735)
- The Art and History of Medicine (HP 4152, J-Term study abroad)
Labs/Teams: Cherrington Lab at the University of Wyoming, focusing on molecular and cellular mechanisms of female reproduction and disease. The lab includes PhD student Ari Tourtellot and collaborates with experts in immunology, endocrinology, and cancer biology.
