جست‌وجوی استاد و پژوهشگر

Jay Gibsonمشاهده پروفایل

دانشیار

• Neuroscience
• Synaptic Plasticity
• Neurodevelopmental Disorders
• +۳ مورد دیگر

Dr. Jay Gibson is an Associate Professor in the Center for Basic Neuroscience at the University of Texas Southwestern Medical Center. He holds a Ph.D. in Biophysics from the University of Rochester and a B.S. in Biophysics from the University of California, Berkeley. His research focuses on neocortical circuitry alterations in Fragile X Syndrome (Fmr1 KO mouse models), emphasizing synaptic plasticity, excitatory/inhibitory balance, and mechanisms underlying neurodevelopmental disorders. Key areas of research include mGluR5 signaling dysfunction, Homer protein scaffolding, and synaptic pruning in cortical networks. Dr. Gibson leads the Gibson Lab, which employs electrophysiological techniques to study circuit dysfunction. Former advisees include Ankur Patel, Seth Hays, and Aundrea Bartley. Publications highlight contributions to understanding Fragile X pathophysiology, including hyperexcitability mechanisms and synaptic dysfunction. Collaborations with institutions like Harvard Medical School and UT Southwestern underscore interdisciplinary approaches in neuroscience.

Jianmin Suمشاهده پروفایل

عضو هیئت علمی

• Synapse Formation
• Neuroscience
• Molecular Neuroscience
• +۵ مورد دیگر

Jianmin Su, Ph.D., is a Research Assistant Professor at the Fralin Biomedical Research Institute at Virginia Tech Carilion (VTC), affiliated with the Weston Lab. His research is focused on the cellular and molecular mechanisms underlying synapse formation, including synaptic targeting, differentiation, and maturation. He is actively involved in neuroscience research with a strong emphasis on synaptic organization and neural circuit development. Education: Ph.D. in Medicine, Fudan University Postdoctoral Fellowship, Virginia Commonwealth University, Medical School/Anatomy Dr. Su's research interests center on synaptic development, particularly the role of extracellular matrix proteins, transmembrane collagens, and signaling molecules such as Reelin and fibroblast growth factors in neural connectivity. His work integrates molecular biology, neuroanatomy, and developmental neuroscience to understand how precise synaptic circuits are established in the brain. His recent publications highlight a consistent focus on synaptic assembly in various brain regions, including the cerebellum, hippocampus, and visual system. Key themes include the role of matricryptins, integrin signaling, and region-specific expression of structural proteins in synaptogenesis. His work often involves mouse models and detailed molecular analysis. Dr. Su has collaborated extensively with Dr. Michael A. Fox and other researchers, contributing to high-impact journals such as Journal of Neuroscience , Cell Reports , and Frontiers journals. While no scientific awards are listed, his publication record demonstrates sustained scholarly output in molecular neuroscience. He advises no listed students, but his role as a research faculty suggests involvement in mentoring junior researchers and lab personnel. His work is supported through institutional affiliations and likely grant funding, though specific grants are not mentioned. Dr. Su is based in the Weston Lab, which focuses on neural development and synaptic function, contributing to a collaborative and interdisciplinary research environment.

Christopher Dullaمشاهده پروفایل

استاد

• Neurotransmission
• Neuronal Network Function
• Epilepsy
• +۴ مورد دیگر

Christopher Dulla is a Professor and Interim Chair of Neuroscience at Tufts University School of Medicine. His research focuses on understanding how neurotransmission shapes neuronal networks, with particular emphasis on epilepsy and traumatic brain injury. He holds the Landis Award for Outstanding Mentorship (2018) and leads a lab using advanced imaging and electrophysiological techniques to study astrocyte-neuron interactions and synaptic dysfunction. Education : Ph.D., University of Colorado, 2005 B.S., University of Arizona, 2000 Research Interests : His lab investigates astrocyte glutamate uptake, GABAergic interneuron development, and metabolic control of neuronal activity. Key areas include the role of astrocytes in epilepsy pathophysiology and the development of novel therapies for traumatic brain injury. Grants & Awards : Multiple NIH grants on epilepsy, glutamate signaling, and traumatic brain injury mechanisms. Ellison Foundation awards for glutamate clearance research. Teaching & Leadership : Teaches courses in Neuroscience and Cell Biology, and serves as Program Director for the Neuroscience Program at Tufts Graduate School of Biomedical Sciences. Active in professional societies, including the American Epilepsy Society. Labs & Teams : His laboratory integrates interdisciplinary approaches to study synaptic dysfunction, with ongoing work on astrocyte physiology and antiepileptogenic therapies.

• Computer Vision
• High Performance Computing
• Data Science
• +۱ مورد دیگر

Kannappan Palaniappan is a Curators' Distinguished Professor in Electrical Engineering and Computer Science at the University of Missouri. His pioneering work spans computer vision, high-performance computing, and biomedical image analysis, with applications from molecular microscopy to satellite remote sensing. Received prestigious honors including NASA Public Service Medal for scientific visualization innovations and National Academies Jefferson Science Fellowship. Research interests include large-scale image analysis, geospatial visualization, biomedical imaging, and parallel computing algorithms. Developed foundational techniques for the Digital Earth visualization system and co-founded NASA's Visualization and Analysis Lab. Publications demonstrate extensive applications across scales from cellular neuroscience to Earth observation. Recent works focus on neural circuit modeling, high-performance computing frameworks, and interdisciplinary applications in neuroscience and geospatial analysis. NASA Public Service Medal National Academies Jefferson Science Fellowship Air Force Summer Faculty Fellowship Boeing Welliver Faculty Fellowship William T. Kemper Teaching Fellowship Secured research funding from NIH, NSF, NASA, and DoD laboratories. Holds patents for moving object detection and camera pose estimation technologies.

• Neuroscience
• Cognitive Neuroscience
• Developmental Biology
• +۳ مورد دیگر

Juan Arellano is a Research Scientist in the Department of Neuroscience at Yale School of Medicine. His research focuses on cortical development, hippocampal neurogenesis, and neurodegenerative mechanisms in primates. Education: PhD in Neuroscience (Complutense University of Madrid) Current Research: Cortical Development, Tau Protein Pathology, Calcium Signaling in Aging Research Themes: Structural and functional organization of the cerebral cortex Mechanisms of tau hyperphosphorylation in aging primates Role of calcium signaling in cognitive decline Comparative neurobiology of hippocampal neurogenesis Genomic regulation of cortical development Neurodegenerative disease modeling Recent Collaborations include work with the Arnsten Lab and Rakic Lab, focusing on primate neuroanatomy and molecular mechanisms of cognition.

Natalia Goriounovaمشاهده پروفایل

دانشیار

• Neuroscience
• Neurophysiology
• Synaptic Transmission
• +۴ مورد دیگر

Dr. Natalia Goriounova is an Associate Professor at the Vrije Universiteit Amsterdam’s Faculty of Science, affiliated with the Integrative Neurophysiology department and Amsterdam Neuroscience (Cellular & Molecular Mechanisms, Systems & Network Neuroscience). Her research focuses on human cortical neuron diversity, synaptic mechanisms, and their roles in cognition and neurological disorders. She leads a multiscale project on IQ-excitability relationships in the human cortex and teaches advanced neuroscience courses. Her work bridges electrophysiology, transcriptomics, and morphological analysis to uncover human-specific neuronal adaptations. Key areas include interneuron diversity, voltage-gated ion channel properties, and synaptic plasticity in human neocortical circuits. Over 37 publications highlight contributions to understanding human brain evolution and cognitive correlates of neuronal properties. Notable recent findings include morpho-electric diversity in hippocampal neurons, human-specific fast-spiking neuron specializations, and genetic links to cognitive ability. She actively contributes to open science through datasets on neuronal properties and cortical evolution, with widespread academic impact.

• Neuroscience
• Immunology
• Molecular Biology
• +۵ مورد دیگر

Xin Du is a Research Fellow in the Department of Biochemistry & Molecular Biology at Monash University. Their research focuses on molecular mechanisms underlying neurodegenerative and immune-related disorders, with a particular emphasis on signaling pathways, receptor interactions, and sex-specific effects in animal models. Key areas of investigation include NMDA receptors, BDNF-TrkB signaling, and the impact of hormonal modulation on cognitive and behavioral outcomes. Research interests span neuropharmacology, immunology, and developmental neuroscience, addressing topics such as maternal immune activation, synaptic plasticity, and the pathophysiology of schizophrenia and autism spectrum disorders. Recent work includes studies on small molecule inhibitors for anti-tumor immunity and the role of parvalbumin interneurons in spatial memory deficits. Publications highlight contributions to understanding the interplay between neuroendocrine systems, stress responses, and cognitive function, with a focus on translational applications in neuroprotective therapies and drug development. No awards or grants are explicitly listed in the provided texts. Advising and lab affiliations are not detailed, though collaborations include studies on gamma oscillations, synaptic dysfunction, and environmental enrichment effects in neurodegenerative models.

Keran Maمشاهده پروفایل

استادیار

• Neuroscience
• Neurodegenerative Diseases
• Alzheimer's Disease
• +۷ مورد دیگر

Keran Ma, PhD, is an Assistant Professor in the Department of Neurobiology and Anatomy at The University of Texas Health Science Center at Houston (UTHealth). Her research focuses on neuron-glia interactions and cellular dysfunction in Alzheimer’s disease (AD), particularly examining aberrant brain oscillations and cognitive deficits. Education: Honors BSc in Toxicology, MSc in Physiology, and PhD in Laboratory Medicine and Pathobiology from the University of Toronto Postdoctoral training at Gladstone Institutes and UCSF Research interests include: Neuronal network abnormalities in AD Microglia and astrocyte modulation of neuronal activity Role of genetic risk factors ApoE and TREM2 Therapeutic strategies targeting neuron-glia interactions She employs advanced tools such as in vivo electrophysiology, 2-photon imaging, machine learning, and RNA sequencing. Her lab investigates neuronal dysfunction in AD mouse models through optogenetics and pharmacological interventions. Scientific awards include: NIH K99/R00 Pathway to Independence Award (NIA) Rising STARs Award (UT System) The Ma lab recruits motivated postdoctoral fellows, graduate students, and research assistants interested in AD pathophysiology and network activity restoration.

• Olfactory System
• Neuroanatomy
• Neurophysiology
• +۳ مورد دیگر

Adam C. Puche, PhD, is a tenured Professor and Vice Chair of the Department of Anatomy and Neurobiology at the University of Maryland School of Medicine. His laboratory investigates olfactory system development, neural circuitry, and function using neuroanatomical, electrophysiological, and advanced imaging techniques. He directs the medical school course Structure and Development , covering gross anatomy, histology, and embryology. Education: Ph.D. in Anatomy and Cell Biology, University of Melbourne (Australia) Post-doctoral training at University of Maryland with Dr. Michael T. Shipley Research Focus: Dr. Puche's work examines: (1) Embryonic/postnatal olfactory system development; (2) Neurogenesis and migration of olfactory interneurons via the rostral migratory stream; (3) Synaptic processing in glomerular microcircuits; (4) In vivo neural activity mapping using calcium imaging and electrophysiology; (5) Clinical applications in trauma training and neurodegenerative diseases. Publication Trends (2019-2025): His recent articles demonstrate strong foci on olfactory bulb neural dynamics, cortical signaling pathways, innovative surgical training models (VR/cadaveric), fluorescence imaging techniques, and neuropathology of brain injury. Computational approaches like AI-based medical imaging analysis are emerging themes. Laboratory: The lab employs multidisciplinary approaches including whole-cell patch clamping, two-photon microscopy, molecular biology, and behavioral assays to study neural circuit mechanisms in rodent models.

• Neuroscience
• Synaptic Transmission
• Cellular Physiology
• +۶ مورد دیگر

Professor Colin Akerman is a Governing Body Fellow at the University of Oxford and leads a neuroscience research group within the Department of Pharmacology. His work focuses on synaptic connections, activity-dependent processes, and their role in neurological disorders like epilepsy and dementia. He teaches undergraduate preclinical Medicine and graduate courses in Pharmacology and Neuroscience, and tutors at Corpus Christi College.

Natalia DeMarcoمشاهده پروفایل

دانشیار

• Neurodevelopment
• Inhibitory Neurons
• Cortical Circuit Assembly
• +۲ مورد دیگر

Natalia DeMarco is an Associate Professor of Neuroscience at the Feil Family Brain & Mind Research Institute, Weill Cornell Medical College. Her lab investigates how genetic programs and neuronal activity interact during early brain development, focusing on inhibitory interneurons and their role in neurological disorders like autism, schizophrenia, and epilepsy. PhD, Columbia University (2007) Postdoctoral Fellowship, Patterson Trust (2009) DeMarco’s research explores mechanisms behind excitatory/inhibitory imbalance in the brain, using mouse models to study: Neurotransmitter roles (glutamate, GABA) in interneuron maturation Electrophysiology and viral tracing for circuit analysis Developmental origins of cortical connectivity Implications for autism, schizophrenia, and epilepsy Her 15 most recent publications (2023–2002) highlight trends in cortical circuit assembly, GABA signaling, and interneuron dysfunction. Keywords span neuroscience, genetics, and neurodevelopmental disorders, with subfields like synaptic connectivity, mouse genetics, and activity-dependent plasticity. Scientific awards include: K99/R00 Pathway to Independence Award (2012) Leon Levy Fellowship (2016) Irma Hirschl Career Scientist Award (2020) 2023 Paper of the Year (Babij, Ferrer et al.) DeMarco mentors MD/PhD students (e.g., Andrew Iannone, Rachel Babij) and collaborates with institutions like NYU, Stony Brook, and INSERM. Her lab, located in Manhattan, utilizes techniques such as optogenetics and in vivo imaging to study cortical development. Grants include R01 funding from NIMH and NINDS.

• Neuroscience
• Neurophysiology
• Synaptic Transmission
• +۳ مورد دیگر

Shaul Hestrin is a Professor at the Department of Comparative Medicine, Stanford University School of Medicine . His research focuses on understanding the neural mechanisms underlying cortical function, with a particular emphasis on synaptic transmission, cortical circuits, and GABAergic interneurons. Current teaching roles include COMPMED 200 (One Health Journal Club), COMPMED 370 (Medical Scholars Research), COMPMED 260 (Laboratory Animal Science Practicum), and directed reading/research courses (COMPMED/NEPR 198/199/299/399). Research Interests: Hestrin's work investigates the physiological and molecular basis of synaptic dynamics, including nicotinic modulation, electrical synapses, and state-dependent neural activity. His studies span cortical layer organization, neurotransmitter receptor kinetics, and the balance of excitation and inhibition in neocortical circuits. Publication Trends: His 15 most recent articles (2009–2020) highlight expertise in cortical neurophysiology, synaptic plasticity, GABAergic neuron function, and neuromodulation. Key themes include nicotinic and GABAergic signaling, electrical synapse dynamics, and the role of neuronal subtypes in circuit behavior.

• Developmental Neuroscience
• Cortical Development
• GABAergic Interneurons
• +۴ مورد دیگر

John Rubenstein is a distinguished Professor of Psychiatry at the University of California, San Francisco (UCSF) Weill Institute for Neurosciences within the School of Medicine. His research focuses on the genetic regulation of brain development, particularly cortical development, GABAergic interneuron formation, and neurodevelopmental disorders including autism spectrum disorders and epilepsy. Stanford BS 1977 Chemistry Stanford Biophysics 1982 Membrane Structure and Biogenesis Stanford MD 1986 Pasteur Institute, Paris Postdoc 1986 Mouse Embryology Stanford Residency 1991 Psychiatry Rubenstein's research spans developmental neuroscience, investigating how genetic factors control the formation of neural circuits, particularly focusing on the role of DLX transcription factors in forebrain development. His work bridges molecular genetics with neurophysiology, examining how disruptions in developmental processes lead to neurodevelopmental disorders. He has pioneered research on GABAergic interneuron development and their role in conditions like autism and epilepsy. Analysis of Rubenstein's recent publications reveals a strong focus on transcriptional regulation of cortical development, particularly the role of DLX genes and enhancer elements in controlling neural cell fate. His work increasingly integrates advanced genomic techniques with traditional developmental biology approaches, examining both mouse models and human tissue to understand conserved mechanisms of brain development. Recent work has expanded into translational applications, including cell therapy approaches for epilepsy. W. Maxwell Cowan Award for Developmental Neuroscience (2021) National Academy of Sciences (2020) Ruane Prize for Outstanding Child and Adolescent Psychiatric Research (2016) National Academy of Medicine (2006) Cajal Club Krieg Cortical Discoverer Award (2004) Rubenstein has secured continuous NIH funding since 1992, currently leading multiple R01 grants focused on genetic studies of cortex structure and development, identification of enhancers defining cortical interneuron types, and genetic control of basal telencephalic development. His laboratory has trained numerous scientists who have gone on to establish independent research careers in neuroscience. The lab maintains strong collaborative relationships with other leading neuroscience institutions and has been instrumental in developing resources for the broader neuroscience community. The Rubenstein lab operates within the UCSF Weill Institute for Neurosciences, collaborating closely with other research groups focused on brain development and neurological disorders. The team employs a multidisciplinary approach combining molecular genetics, genomics, electrophysiology, and behavioral analysis to understand the mechanisms underlying proper brain development and how disruptions lead to neurodevelopmental conditions.

Shane Crandallمشاهده پروفایل

استادیار

• Neuroscience
• Systems Neuroscience
• Cortical Circuits
• +۴ مورد دیگر

Shane Crandall serves as Assistant Professor in the Department of Physiology and BioMolecular Science Gateway at Michigan State University, where he directs research in the Neuroscience Program. His laboratory operates from the Biomedical Physical Sciences Building (Room 2100) in East Lansing, Michigan. His academic training includes: B.A. in Neuroscience, Boston University (2005) Ph.D. in Neuroscience, University of Illinois Urbana-Champaign (2012) Postdoctoral Fellowship, Brown University (2012-2017) Dr. Crandall's research program investigates neural circuit mechanisms underlying sensory perception, with primary focus on dynamic neocortex-thalamus interactions. His laboratory examines how these circuits process signals essential for sensation, movement, and cognition, and how their dysfunction contributes to neurological disorders including epilepsy and Tuberous Sclerosis Complex (TSC). Key methodologies include: Electrophysiological and optical recording in awake behaving mice Multi-scale circuit analysis from single neurons to network dynamics Studies of corticothalamic and intracortical pathway modulation TSC-related circuit abnormality characterization Analysis of recent publications (2022-2024) reveals intensifying focus on layer 6 corticothalamic feedback circuits and motor-sensory integration. His team employs selective optical stimulation to dissect parallel pathways, demonstrating how specific interneuron subtypes (particularly somatostatin-expressing) mediate top-down modulation of somatosensory processing. This work establishes critical links between circuit dynamics and neurological disease mechanisms. Dr. Crandall actively mentors postdoctoral researchers, Ph.D. students, and undergraduates, with current recruitment ongoing for all levels. His laboratory maintains strong collaborative ties within MSU's Neuroscience Program and Department of Physiology. The research facility in Biomedical Physical Sciences Building integrates advanced electrophysiology with optical techniques for comprehensive neural circuit analysis in both in vitro and awake behaving preparations, supporting investigations into fundamental sensory processing mechanisms and disease models.

Todd C Holmesمشاهده پروفایل

استاد

• Neural Circuit Mapping
• Synaptic Connectivity
• Visual Cortex
• +۳ مورد دیگر

Todd C. Holmes, PhD, is a Professor in the Department of Physiology & Biophysics at the University of California, Irvine (UCI) School of Medicine. His research focuses on the structural and functional organization of neural circuits, particularly in the visual cortex and hippocampus. Dr. Holmes employs advanced techniques like laser scanning photostimulation and viral tracing to map synaptic connectivity, emphasizing the balance between excitatory and inhibitory inputs in cortical microcircuits. His work has revealed layer-specific synaptic wiring diagrams and redefined understanding of how inhibitory connections mirror excitatory pathways in the mouse visual cortex (V1). Dr. Holmes is affiliated with the UCI Center for Neural Circuit Mapping, contributing to interdisciplinary studies on Alzheimer’s disease models, optogenetic tools, and neurovascular interactions. He has secured funding from NIH grants (e.g., MH105427, R01NS095355) and collaborates on projects involving genetic engineering and high-resolution brain imaging techniques. His research extends to circadian rhythms, Drosophila neurobiology, and neuropsychiatric disorder models, leveraging transgenic approaches and behavioral analyses. Recent studies explore microglia’s role in synaptic connectivity and the application of novel viral vectors for circuit tracing.