Adam C. Puche

Adam C. Puche, PhD, is a tenured Professor and Vice Chair of the Department of Anatomy and Neurobiology at the University of Maryland School of Medicine. His laboratory investigates olfactory system development, neural circuitry, and function using neuroanatomical, electrophysiological, and advanced imaging techniques. He directs the medical school course Structure and Development, covering gross anatomy, histology, and embryology.

Education:

• Ph.D. in Anatomy and Cell Biology, University of Melbourne (Australia)
• Post-doctoral training at University of Maryland with Dr. Michael T. Shipley

Research Focus:
Dr. Puche's work examines: (1) Embryonic/postnatal olfactory system development; (2) Neurogenesis and migration of olfactory interneurons via the rostral migratory stream; (3) Synaptic processing in glomerular microcircuits; (4) In vivo neural activity mapping using calcium imaging and electrophysiology; (5) Clinical applications in trauma training and neurodegenerative diseases.

Publication Trends (2019-2025):
His recent articles demonstrate strong foci on olfactory bulb neural dynamics, cortical signaling pathways, innovative surgical training models (VR/cadaveric), fluorescence imaging techniques, and neuropathology of brain injury. Computational approaches like AI-based medical imaging analysis are emerging themes.

Laboratory:
The lab employs multidisciplinary approaches including whole-cell patch clamping, two-photon microscopy, molecular biology, and behavioral assays to study neural circuit mechanisms in rodent models.