جست‌وجوی استاد و پژوهشگر

Zeribe Nwosuمشاهده پروفایل

استادیار

• Cancer Metabolism
• Pancreatic Cancer
• Therapeutic Targeting
• +۷ مورد دیگر

Zeribe Nwosu is an NIH Cornell Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Assistant Professor in the Department of Molecular Biology and Genetics at Cornell University. His research focuses on cancer metabolism, particularly pancreatic cancer, with emphasis on nutrient utilization, tumor microenvironment interactions, and therapeutic strategies to disrupt metabolic pathways. He holds a PhD in Molecular and Cellular Biology from the University of Heidelberg, Germany, and completed postdoctoral training at the University of Michigan, where he studied pancreatic cancer metabolism. Education: Bachelor of Medical Laboratory Science, Ebonyi State University, Nigeria (2007) MSc in Biomedical Science, London Metropolitan University, UK (2012) PhD in Molecular and Cellular Biology, University of Heidelberg, Germany (2017) Postdoctoral Research Fellow, University of Michigan, USA (2023) Research Interests: Identification of nutrient transporters and metabolic regulators in cancer cells Role of glutathione (GSH) in pancreatic cancer survival and drug resistance Impact of metabolic diseases (e.g., diabetes) on cancer progression Development of novel drug combinations targeting metabolic vulnerabilities Integration of functional genomics and drug screening for therapeutic discovery Awards & Funding: NIH K99/R00 Pathway to Independence Award (2023) AACR Scholar-in-Training Award (2023) Funded by NIH/NCI, Cornell University, and the FIRST program Labs & Teams: The Nwosu Lab utilizes cutting-edge technologies including metabolomics, CRISPR/Cas9, Seahorse analysis, and mouse models to study cancer metabolism. Key collaborations involve bioinformatics and clinical translation.

• Plant Pathology
• Microbial Ecology
• Environmental Biotechnology
• +۳ مورد دیگر

Professor Stephen A Rolfe is a Professor of Plant and Microbial Science at the University of Sheffield's School of Biosciences. He holds the Chair in Plant Science and leads the P3 Wolfson Centre for Plant Disease Phenomics. His research focuses on plant responses to biotic/abiotic stresses, using imaging techniques like chlorophyll fluorescence and multispectral imaging, with applications in Brassica diseases (e.g., clubroot) and microbial community analysis. He has a PhD from the University of Cambridge (1988) and served as Director of Teaching in the Department of Animal and Plant Sciences (2008–2015). Awards include the Departmental Teacher of the Year (2007). Education: BSc (Imperial College London, 1984), PhD (Cambridge, 1988), European Molecular Biology Fellow at UCLA (1988–1991). Current roles include external examiner at Reading University and Scotland's Rural College. Research groups include studies on clubroot pathogen Plasmodiophora brassicae and bioremediation of contaminants like ETBE. Teaching spans undergraduate to postgraduate levels, including modules on plant physiology, environmental microbiology, and ethics in biology. His work is funded by BBSRC, Wolfson Foundation, and industry partners like Shell Aviation. The lab explores quantitative disease resistance, root microbiome dynamics, and xenobiotic degradation in contaminated environments. Key collaborations involve Airbus and Bayer Crop Sciences, advancing plant phenotyping and environmental biotechnology. His research group includes students like Luke Cartwright and Elisa Clagnan, focusing on topics such as biofilm formation in aviation systems and microbial community dynamics in polluted aquifers.

• Immunology
• Proteomics
• Mass Spectrometry
• +۳ مورد دیگر

Prof. Felix Meissner is a Professor and Head of the Department of Systems Immunology & Proteomics at the Institute of Innate Immunity, University Hospital Bonn. His research focuses on understanding immune signaling circuits using mass spectrometry-based proteomics, systems biology, and biochemical approaches. He investigates how self/non-self signals are sensed and transmitted in immune systems to regulate inflammation and immunity. Education & Career: Biochemistry studies at Free University of Berlin and Scripps Research Institute Doctorate at Max Planck Institute for Infection Biology Postdoctoral work at Max Planck Institute of Biochemistry and UCSF Independent Group Leader at MPI of Biochemistry (Munich) Since 2021: Professor at University of Bonn Research Interests: Proteomics-driven discovery of immune signaling pathways Systems-level analysis of inflammation regulation Development of novel proteomic tools (e.g., EASI-tag) Translational applications in drug discovery and therapeutics Labs & Collaborations: Joint lab at University of Bonn and Max Planck Institute of Biochemistry Co-founder of Odyssey Therapeutics (translating proteomic discoveries) Key projects: Target deconvolution, intercellular communication analysis

Christopher Deppmannمشاهده پروفایل

استاد

• Neurobiology
• Developmental Biology
• Axon Guidance
• +۵ مورد دیگر

Christopher Deppmann is a Professor of Biology at the University of Virginia, Department of Biology. His lab focuses on neural circuit assembly and disassembly, particularly in the peripheral nervous system. Key areas of research include neurotrophin signaling, cytokine interactions, and axon degeneration mechanisms. Collaborations include work with the Güler lab on non-invasive neurotechnology tools. Education: B.S. in Biology from Western Michigan University (1997), Ph.D. in Biochemistry & Molecular Biology from Purdue University (2003), postdoctoral training at Johns Hopkins University School of Medicine (2003-2009). Research interests emphasize antagonistic cytokine signaling in nervous system refinement, TNFR signaling pathways, and translational applications to neurodegenerative diseases, pain, and metabolism. Current projects span undergraduate, graduate, and postdoctoral training opportunities. Lab locations include the Physical and Life Sciences Building (PLSB), with an office in 314 PLSB and lab space in 440 PLSB. Positions are available across all training levels.

Ariel Paniمشاهده پروفایل

استادیار

• Developmental Biology
• Molecular Biology
• Cell Biology
• +۳ مورد دیگر

Ariel Pani is an Assistant Professor of Biology at the University of Virginia. His research focuses on developmental biology, particularly using the C. elegans model organism to study cell migration, signaling pathways, and organogenesis. He leads the Pani Lab, which explores processes such as FGF-dependent muscle progenitor migration and Wnt signaling dynamics. Education B.A., Cornell University, College Scholar in Organismal Biology (2004) Ph.D., University of Chicago, Evolutionary Biology (2013) Postdoctoral Research, University of North Carolina at Chapel Hill (2013–2019) His research interests include molecular mechanisms of cell behavior, evolutionary developmental processes, and the role of transcription factors in cellular decisions. His lab has developed novel genetic tools for studying Notch and Wnt signaling pathways in vivo. Publications highlight his work on C. elegans organogenesis, microtubule dynamics during meiosis, and the molecular characterization of nervous systems in hemichordates. He collaborates widely, with studies often involving interdisciplinary approaches to developmental biology. The Pani Lab is equipped to investigate cellular processes using advanced microscopy, CRISPR-based genome engineering, and transcriptome analysis. Ongoing projects aim to unravel how physical forces and molecular signals coordinate during development.

Ian Stuart Hitchcockمشاهده پروفایل

استاد

• Hematology
• Blood Disorders
• Hematopoiesis
• +۵ مورد دیگر

Ian Stuart Hitchcock is a Professor in the Department of Biology at the University of York. His research focuses on hematopoiesis, thrombosis, and immune-mediated blood disorders, with a particular emphasis on the thrombopoietin receptor (MPL) and its role in platelet production and hematopoietic stem cell differentiation. He is also Theme Lead at the York Biomedical Research Institute and has held roles including Lecturer in Biomedical Sciences and Research Associate at York. His work spans molecular mechanisms underlying blood disorders, such as myelofibrosis and essential thrombocythemia, and explores imaging technologies like holotomography for cell signaling analysis. Collaborations include studies on infectious diseases (leishmaniasis, malaria) and their hematological impacts, alongside projects investigating stromal microenvironments and extracellular matrix effects on hematopoiesis. Dr. Hitchcock’s research integrates experimental and computational approaches, contributing to both basic science and translational medicine. His recent studies highlight the structural basis of MPL signaling, the impact of chronic infections on hemostasis, and novel imaging techniques for real-time cellular analysis.

Dhananjay Yellajoshyulaمشاهده پروفایل

استادیار

• Neurodevelopmental Disorders
• Oligodendrocyte Lineage Development
• Extracellular Matrix Regulation
• +۵ مورد دیگر

Dr. Dhananjay Yellajoshyula is an Assistant Professor in the Department of Neurosciences at Case Western Reserve University's School of Medicine. His research focuses on understanding the interplay between oligodendrocyte lineage development and extracellular matrix (ECM) regulation in neurodevelopmental disorders, particularly DYT6 dystonia. He leads the Yellajoshyula Lab, which investigates mechanisms underlying myelination defects and motor circuit dysfunction. Dr. Yellajoshyula holds a PhD in Biochemistry and has extensive academic appointments and collaborations. Education: PhD in Biochemistry, University of Mississippi Medical Center (2006) MSc in Biotechnology, Madurai Kamaraj University (1999) BSc in Genetics & Chemistry, Nizam College (1997) Research Interests: Dr. Yellajoshyula’s work centers on transcriptional networks regulating oligodendrocyte maturation and ECM dynamics. His lab uses mouse genetics and in vitro models to study dystonia pathogenesis, focusing on how mutations in THAP1 disrupt myelination and motor function. Recent studies highlight ECM homeostasis and its role in neurodevelopmental disorders. Awards & Grants: 2024 Mizutani Foundation for Glycoscience Grant 2023 Dystonia Medical Research Foundation Support Lab & Collaborations: The lab hosts trainees like Keenan Hope (PhD student) and Bingmin Luo (postdoc), supported by grants. Key projects include studying THAP1-YY1 interactions and ECM contributions to CNS function.

• Lipid Biochemistry
• Thrombosis
• Innate Immunity
• +۴ مورد دیگر

Professor Valerie O'Donnell is a leading academic in lipid biochemistry at Cardiff University's School of Medicine, specializing in the Division of Infection and Immunity. Her research focuses on lipid signaling in thrombosis, innate immunity, and vascular diseases using mass spectrometry. Key areas include enzymatically oxidized phospholipids (eoxPL) and their roles in blood clotting, inflammation, and conditions like atherosclerosis and dementia. She leads the LIPID MAPS initiative, a global lipidomics resource, and her work has advanced understanding of lipid mediators in viral envelopes (e.g., SARS-CoV-2) and aspirin's effects. Awards include FLSW, FMedSci, and an OBE. Research Interests: Procoagulant lipids, oxylipin metabolism, lipidomics standardization, and cardiovascular disease mechanisms. Grants: MRC Partnership Grant (2024), British Heart Foundation Program Grant. Labs/Teams: O'Donnell Lab (Cardiff), collaborating with institutions like Babraham Institute and University of Cambridge. Her >250 publications include seminal work on lipid biomarkers and their clinical applications, with recent focus on aging-related inflammation and viral pathogenesis.

Reinoud Gosensمشاهده پروفایل

استاد

• Respiratory System
• Pharmacology
• Tissue Repair
• +۴ مورد دیگر

Reinoud Gosens is a Professor of Translational Pharmacology at the University of Groningen , affiliated with the Faculty of Science and Engineering and the Department of Molecular Pharmacology . His research focuses on mechanisms regulating tissue repair and remodeling in asthma and COPD, particularly targeting neuronal signaling, Wnt/Frizzled receptors, and novel drug candidates. Education: PhD in Pharmacology (cum laude), University of Groningen (2004) MSc in Pharmacy (cum laude), University of Groningen (2000) Research Interests: His work integrates molecular pharmacology and translational research to address chronic lung diseases. Key areas include WNT signaling in fibrosis, neuroimmune interactions in asthma, and regenerative therapies for COPD. He has pioneered studies on the role of acetylcholine in inflammation and the therapeutic potential of anticholinergics. Awards & Grants: Prix Galien Research Award (2018) NWO Vidi (2012) and Veni (2007) grants Over 30 grants from institutions like the Netherlands Lung Foundation and Boehringer Ingelheim Academic Roles: He chairs the Groningen Research Institute for Asthma and COPD (GRIAC) and serves on editorial boards of journals like Respiratory Research and Frontiers in Physiology . He also holds leadership roles in professional societies such as the American Thoracic Society (ATS) and European Respiratory Society (ERS). Labs/Teams: His lab focuses on in vitro models of lung repair, including organoids and precision-cut lung slices. Collaborations include projects on lung regeneration and drug discovery for COPD.

• Rheumatology
• Immunology
• Autoimmune Diseases
• +۳ مورد دیگر

Dr Alessandra Nerviani is a Clinical Research Fellow at the William Harvey Research Institute, Queen Mary University of London. Her work focuses on rheumatoid arthritis (RA) and other autoimmune conditions, with a particular emphasis on synovial tissue pathobiology, biomarker discovery, and treatment response mechanisms. She contributes to clinical trials like the R4RA trial, investigating therapeutic strategies such as rituximab and tocilizumab. Her research integrates molecular profiling, histopathology, and cellular analysis to define disease subtypes and improve patient stratification for targeted therapies. Key research interests include TAM receptors (Axl/MerTK), synovial inflammation pathways, and the role of B cells and macrophages in disease progression. She has published extensively on synovial tissue signatures, biomarkers for disease activity, and mechanisms underlying treatment resistance in RA and related conditions. Collaborative projects involve multi-omic approaches to identify novel therapeutic targets and improve clinical outcomes for autoimmune patients. Grants: Involved in R4RA trial funding, biomarker discovery initiatives, and drug mechanism studies. Labs: Works within the William Harvey Research Institute's rheumatology and immunology research groups.

Sergio Crespo-Garciaمشاهده پروفایل

استادیار

• Retina Degeneration
• Diabetes
• Ophthalmology
• +۳ مورد دیگر

Sergio Crespo-Garcia is an Assistant Professor at the University of Montreal, affiliated with both the School of Optometry and the Department of Pharmacology and Physiology within the Faculty of Medicine. His research focuses on retinal degeneration, diabetes, and vascular biology, particularly investigating interactions between retinal blood vessels and cellular senescence in ocular diseases. Education: B.Sc. in Biology (2012, IE University, Spain) M.Sc. in Cellular Biology (2013, Universidad Complutense de Madrid) Post-graduate Certificate in Ophthalmology (2016, University of Lincoln, UK) Dr. rer. med. in Biomedical Sciences (2017, Charité Universitätsmedizin Berlin) Postdoctoral training in Medical Biochemistry (2022, Maisonneuve-Rosemont Hospital Research Center, Canada) Research Interests: His work explores mechanisms underlying retinal vascular diseases, including diabetic retinopathy and age-related macular degeneration. Key areas include cellular senescence, metabolic pathways, and therapeutic approaches targeting senescent cells using senolytics. He investigates how senescent cells contribute to pathological angiogenesis and vascular dysfunction. Notable Achievements: Recipient of the HMR Foundation Publication Prize (2022) and Relève Étoile Jacques-Genest Award (2021) for work in Cell Metabolism . Developed novel models for diabetic retinopathy and identified therapeutic targets like BCL-xL inhibitors. Leading projects funded by agencies such as FRQS, CRSNG, and the Canadian Heart & Stroke Foundation. Grants & Collaborations: He leads or co-leads multiple grants, including studies on glycocalyx intercellular causality (CRSNG), faulty perivascular metabolism (Heart & Stroke Foundation), and pre-clinical assays for geographic atrophy (RRSV Network). Labs & Teams: Runs a lab focusing on neurovascular interactions in the retina, collaborating with the Marie Curie Alumni Association and networks like GRUM and RRSV.

Nicolas Santiمشاهده پروفایل

استادیار

• Infectious Diseases
• Immunology
• Virology
• +۳ مورد دیگر

Nicolas Santi, MD, FRCPC, DRCPSC is an Assistant Professor with a focus on infectious diseases, immunology, and HIV research. His work spans clinical practice improvements, virological investigations, and immune system dynamics in chronic infections. Current research emphasizes SARS-CoV-2 antibody responses, HIV pathogenesis, and extracellular vesicle-mediated immune modulation. He has contributed to large-scale studies on antiviral therapies (e.g., remdesivir, sotrovimab) and pandemic response strategies in healthcare settings. Key collaborations include the WHO Solidarity Trial and the Canadian Treatments for COVID-19 (CATCO) initiative. His studies often bridge clinical outcomes with molecular mechanisms, particularly in immune cell dysfunction and recovery patterns post-treatment.

Ilyas Khanمشاهده پروفایل

دانشیار

• Cartilage biology
• Stem cells and progenitor cells
• Tissue engineering
• +۵ مورد دیگر

Dr. Ilyas Khan is an Associate Professor in Biomedical Sciences at Swansea University's Medical School. His research focuses on regenerative medicine and tissue engineering, particularly in developing cartilage repair solutions for joint diseases like osteoarthritis. He leads a lab investigating stem cells' role in cartilage development, 3D tissue engineering, and translational clinical applications with NHS collaboration. Dr. Khan holds a PhD from Imperial College London (1996–2000) and has secured significant grants, including a £1.3M project (2014–2020) with Utrecht University. He teaches modules on regenerative medicine and supervises postgraduate students in areas like BMP9-induced cartilage maturation and synthetic bone allografts. His work bridges basic science and clinical translation, emphasizing global research impact. Teaching includes undergraduate courses on regenerative medicine and advanced nanomedicine modules. Collaborations span European and global institutions. Key research themes include stem cell biology, cartilage progenitor cells, and bioprinting. Scientific output includes over 20 peer-reviewed articles, with recent focus on BMP9 signaling and 3D scaffold technologies.

• Immunology
• Oncology
• Virology
• +۳ مورد دیگر

Prof. C.A.H.H. (Toos) Daemen is a full Professor at the Faculty of Medical Sciences, University of Groningen, affiliated with the Department of Medical Microbiology. Her research focuses on immunotherapy strategies targeting virus-induced cancers, particularly HPV- and HCV-related malignancies. She leads projects on alphavirus vector-based therapies and co-founded ViciniVax BV, a spin-off company developing immunotherapeutic vaccines. Key areas include oncolytic virotherapy, macrophage reprogramming, and vaccine design. Education: 1983: MSc in Medical Biology (University of Utrecht) 1987: PhD in Immunotherapy of liver metastases (University of Groningen) Research Interests: Activation of innate and adaptive immunity for cancer treatment Genetic immunization using viral vectors Preclinical development of therapeutic vaccines Notable Achievements: Founded ViciniVax BV (2009) Phase II clinical trials for HPV16-positive cervical neoplasia Over 190 peer-reviewed publications Advising & Grants: Collaborates extensively on vaccine development and cancer immunotherapy projects, though specific grant details are not explicitly listed. Labs/Teams: Active in the Molecular Virology section and Gynaecologic Oncology departments at UMCG.

Amalia Dolgaمشاهده پروفایل

استاد

• Neuroscience
• Cell Death
• Ferroptosis
• +۷ مورد دیگر

Amalia Dolga is a Professor at the University of Groningen, holding positions in the Faculty of Science and Engineering, the Molecular Pharmacology department of the Faculty of Medical Sciences/UMCG, and the Groningen Research Institute for Asthma and COPD (GRIAC). With 146 research outputs to her name, she maintains an active research program with publications extending into 2025, demonstrating ongoing scholarly productivity. University: University of Groningen School: Faculty of Science and Engineering Department: Molecular Pharmacology Institutional Affiliations: Faculty of Medical Sciences/UMCG, Groningen Research Institute for Asthma and COPD (GRIAC) Professor Dolga's research spans multiple neuroscience domains with particular focus on cell death mechanisms, ferroptosis, SK channels, mitochondrial function, Alzheimer's disease, glutamic acid pathways, neuroprotective agents, and oxidative stress. Her work demonstrates a strong interdisciplinary approach connecting molecular pharmacology with neurological disorders, particularly neurodegenerative conditions. She has developed expertise in studying neuronal excitability, protein aggregation mechanisms, and mitochondrial DNA methylation. Her recent publications reveal a consistent focus on neurodegenerative disorders with particular emphasis on Alzheimer's disease, Huntington's disease, and Parkinson's disease mechanisms. The research shows sophisticated methodologies including brain-on-a-chip models, advanced mass spectrometry techniques, and detailed cellular stress analysis. A significant trend in her work involves developing therapeutic approaches targeting specific molecular pathways in neurodegeneration. Stichting ParkinsonFonds Research Grant (2019) Alzheimer Nederland Research Grant (2018) Molecular Life and Health Fellowship (2017) ZonMw MKMD Neuro-Chip Grant (2017) Noordelijke Cara Stichting Grant (2016) Professor Dolga actively supervises PhD students including Xun Zhang and has served as co-supervisor on multiple doctoral committees. Her research program has attracted substantial funding including a ZonMw Open Competition Grant for studying LRRK2 effects on neuron-microglia communication in Parkinson's disease. She has developed innovative brain-on-a-chip models for testing future therapies targeting neurodegenerative conditions. Her laboratory work integrates molecular pharmacology with advanced cellular models, particularly focusing on mitochondrial function in neurodegeneration and the role of ion channels in neuronal health. Professor Dolga collaborates extensively with researchers across the University of Groningen including with Arjan Kortholt and Erik Boddeke on Parkinson's disease research.