جستجوی استاد راهنمای دانشگاهی

Xi Chen is an Assistant Professor at the Department of Biology, Southern University of Science and Technology (SUSTech), since 2019. He previously worked as a Senior Staff Scientist at the Wellcome Sanger Institute (2016–2019) and Postdoctoral Fellow at the European Bioinformatics Institute (2013–2016). His academic journey includes a PhD in Life Sciences (2009–2012) and BSc in Experimental Medicine (2005–2009) from the University of Manchester and Peking University Health Science Center respectively. Education: PhD, Life Sciences, University of Manchester (2009–2012) BSc, Experimental Medicine, Peking University Health Science Center (2005–2009) Research Interests focus on: Developing single-cell epigenetic and transcriptomic sequencing technologies Epigenetic and bioinformatic analysis of genomic data Using T cells and stem cells as models to study transcription factors and chromatin complexes in cell fate determination and memory Recent Publications highlight his work in single-cell genomics (2018–2019), with methodological advances like rapid chromatin accessibility profiling and insights into T helper cell CRISPR screens, embryonic stem cell differentiation, and innate immunity variability. His publications span high-impact journals including Cell , Nature , and Nucleic Acids Research . Labs & Collaborations: Xi Chen leads the xichenlab.com , a hub for single-cell genomics research. The lab recruits postdocs and research assistants for both computational (dry lab) and experimental (wet lab) roles, emphasizing interdisciplinary collaboration and access to SUSTech's supercomputing resources.

• Single Cell Genomics
• Transcription Factors
• Chromatin Complexes
• +۴ مورد دیگر

Sicong He is a Tenure-Track Assistant Professor at the School of Life Sciences, Southern University of Science and Technology (SUSTech), where he also holds a joint appointment with the Department of Biomedical Engineering. He received his B.Eng. in Optical Engineering from Zhejiang University in 2012 and his Ph.D. in Electronic and Computer Engineering from the Hong Kong University of Science and Technology in 2017. Following his doctoral studies, he completed a postdoctoral fellowship at the Hong Kong University of Science and Technology from 2017 to 2020 before joining SUSTech in December 2020. Dr. He's educational background includes: Ph.D., Electronic and Computer Engineering, Hong Kong University of Science and Technology (2012-2017) B.E., Optical Engineering, Zhejiang University (2008-2012) Dr. He's research focuses on the development of novel optical imaging techniques and their biological applications. His work spans three primary areas: adaptive-optics multiphoton fluorescence microscopy for high spatial-temporal resolution imaging, high resolution infrared laser-mediated gene induction microscopy for in vivo single-cell labeling and lineage tracing, and multimodal nonlinear optical microscopy integrating multiphoton fluorescence imaging, second/third harmonic generation, and stimulated Raman scattering. His research bridges optics, engineering, and life sciences, with applications in neuroscience, developmental biology, and hematology. He has developed imaging techniques that enable unprecedented visualization of biological processes at cellular and subcellular levels in living organisms. Analysis of Dr. He's publication record reveals a strong focus on advanced optical microscopy techniques applied to biological systems. His work demonstrates expertise in developing and applying adaptive optics, infrared laser-mediated techniques, and multimodal nonlinear optical imaging approaches. These techniques have been successfully applied to diverse biological questions spanning neuroscience (spinal cord imaging, brain imaging), developmental biology (lineage tracing in zebrafish), hematology (blood cell development), and metabolism (brown and beige fat studies). Dr. He has received several honors and awards including: Postgraduate Scholarship of Hong Kong University of Science and Technology (2012-2017) Top 100 Undergraduate Thesis Prize of Zhejiang University (2012) As a PhD supervisor at SUSTech, Dr. He mentors graduate students in interdisciplinary research at the intersection of optics, engineering, and life sciences. His laboratory likely focuses on developing next-generation optical imaging technologies while exploring their applications in various biological systems. He teaches undergraduate courses including Systems Biology (BIO304) and Signals and Systems (EE205), as well as the graduate course Advanced Techniques in Biomedical Imaging (BIO5038). Dr. He's laboratory is likely located in Room 410, Research Building 2 at SUSTech, where he continues to develop innovative optical imaging techniques and apply them to challenging biological questions.

• Optical Imaging Technology
• Biomedical Engineering
• Microscopy Techniques
• +۷ مورد دیگر

Heng Xu is an Associate Professor at the Institute of Theoretical and Interdisciplinary Physics within the School of Physics and Astronomy at Shanghai Jiao Tong University . His work bridges physics and biology to study living systems through quantitative methods. Education: Bachelor's in Physics (2003), Nanjing University PhD in Physics (2010), Brown University Dr. Xu's research focuses on transcriptional regulation in Drosophila melanogaster embryos, combining high-resolution fluorescence imaging , quantitative analysis , and stochastic modeling . His publications span biophysics, neurophysiology, and imaging technologies. Scientific Awards: Burroughs Wellcome Fund Career Award at the Scientific Interface (2014) Thousand Talents Program for Young Professionals (2017) Dr. Xu's lab develops optical tools for biological applications and investigates gene regulatory networks . He has contributed to single-cell analysis techniques and neuronal activity studies in model organisms.

• Gene Regulatory Networks
• Embryonic Development
• Quantitative Biology
• +۳ مورد دیگر

Deng Yi is a Teaching Professor in the Department of Biology at Southern University of Science and Technology (SUSTech), where she has established herself as a leading researcher in cell-matrix adhesion mechanisms and their implications for disease. She joined SUSTech in 2012 as an Associate Professor and was promoted to Teaching Professor in 2020, following extensive postdoctoral training at the National Institutes of Health (NIH) in the United States. Educational Background: PhD in Biology from Ruhr-University Bochum (Germany), 2002 MS in Biology from Shandong University, 1999 BS in Biology from Shandong University, 1996 Research Interests: Dr. Deng's research program focuses on understanding the molecular mechanisms of cell-extracellular matrix interactions and their relationship to health and disease. Her laboratory investigates how cell-matrix adhesions regulate cell motility, growth, and signaling pathways through the formation of key protein complexes including ILK-PINCH-parvin and kindlin-migfilin-filamin. Using advanced fluorescence microscopy techniques combined with biochemical approaches, her team studies these dynamic processes at multiple spatial scales. Her work has significant implications for understanding cancer metastasis, tumor development, and pancreatic beta-cell function in diabetes. Publication Trends: Analysis of Dr. Deng's recent publications reveals a strong focus on integrin-mediated cell adhesion mechanisms, with increasing attention to cancer biology applications in her most recent work. Her research spans developmental biology using Xenopus models, structural biology of adhesion proteins, and translational studies in diabetes and cancer. The consistent use of advanced imaging techniques and molecular approaches demonstrates methodological coherence across her publication portfolio. Scientific Recognition: Extensive publication record in high-impact journals including PNAS, Journal of Biological Chemistry, and Oncogene Research contributions to understanding kindlin-mediated integrin activation mechanisms Significant findings on RSU1 regulation of MEK-ERK signaling in tumor development Teaching and Mentoring: Dr. Deng is actively involved in undergraduate education at SUSTech, teaching core courses including Molecular Biology (BIO320), Cell Biology (BIO206), and Advanced Cell Biology (BIO323). She emphasizes hands-on research experience for students and integrates her cutting-edge research findings into classroom instruction. Her laboratory provides research opportunities for undergraduate and graduate students interested in cell biology and disease mechanisms. Research Infrastructure: Dr. Deng leads a well-equipped research team within the Department of Biology at SUSTech, utilizing advanced cell biology techniques including live-cell imaging and fluorescence-based technologies. Her laboratory collaborates with other research groups at SUSTech and maintains connections with international collaborators, particularly in Germany and Hong Kong where she conducted earlier research.

• Cell-Matrix Adhesion
• Signal Transduction
• Cancer Metastasis
• +۳ مورد دیگر

Andrew Hutchins is an Associate Professor in the Department of Biology at Southern University of Science and Technology (SUSTech). His research bridges computational and experimental approaches, focusing on next-generation sequencing technologies to study epigenetics, transposable elements, and their roles in cell biology and human disease. PhD from John Innes Centre and University of East Anglia (UK), 2004 BSc from University of Wolverhampton (UK), 2000 His research explores how transposable elements contribute to epigenetic control and cell fate decisions, with implications for understanding developmental processes and diseases. Key areas include chromatin accessibility, single-cell transcriptomics, and reprogramming mechanisms. Recent publications highlight his expertise in computational genomics, RNA-seq, and epigenetic regulation of transposable elements across stem cells and developmental contexts. His work employs advanced bioinformatics tools to analyze chromatin dynamics and transcriptome modulation. At SUSTech, he teaches Bioinformatics and Genomics and Scientific Writing postgraduate courses. He collaborates with international institutions and leads the Chrom Lab, which focuses on interdisciplinary research integrating genomic technologies and computational methods.

• Computational Biology
• Cell Biology
• Epigenetics
• +۷ مورد دیگر

Dr. Chen Hao is an Assistant Professor at the School of Medicine, Southern University of Science and Technology (SUSTech), where he serves as a doctoral supervisor. Previously, he completed postdoctoral training at Boston Children's Hospital, Harvard Medical School. His research focuses on epigenetic mechanisms in human disease, particularly tumor development and metabolic disorders such as diabetes and obesity. Dr. Chen received his academic training at prestigious Chinese institutions: PhD in Molecular Biology & Disease Proteomics, Fudan University (2013) B.S. in Biology, Wuhan University (2008) Dr. Chen's research program investigates epigenetic mechanisms underlying human diseases, with a particular focus on novel epigenetic modifications and their regulatory enzymes. His lab employs biochemical techniques combined with multi-omics approaches to identify and characterize RNA/DNA epigenetic modification enzymes. Key research areas include: Epigenetic mechanisms in cancer development Novel RNA/DNA epigenetic modifications and their modulators Metabolic disease epigenetics (diabetes, obesity, hypertension) mRNA translation mechanisms and mRNA drug development Analysis of Dr. Chen's recent publications reveals a strong focus on RNA epigenetics, particularly m6A methylation and related modifications. His work spans structural biology of methyltransferases (METTL4, METTL5, METTL15), functional studies of RNA modification enzymes, and exploration of how epigenetic dysregulation contributes to diseases including cancer, metabolic disorders, and cardiovascular conditions. His research often bridges basic molecular mechanisms with potential clinical applications. Dr. Chen has received several prestigious awards and honors: Guangdong Province "Pearl River Talent" Young Top-notch Talent Shenzhen "Peacock Plan" Overseas High-level Talent National Scholarship from Chinese Ministry of Education (2012) Magna cum Laude from Fudan University (2013) F1000 recommended paper for METTL4 research Dr. Chen has secured significant research funding, serving as principal investigator for National Natural Science Foundation of China projects and as sub-project leader for National Key R&D Program initiatives. His collaborative research spans multiple disciplines, connecting epigenetics with cancer biology, metabolic disease, and stem cell research. He actively mentors graduate students and postdoctoral fellows in his laboratory. Dr. Chen leads a research group focused on epigenetic mechanisms at SUSTech, utilizing advanced biochemical and multi-omics approaches. His team works at the intersection of basic epigenetic research and translational applications, seeking to identify novel epigenetic targets for therapeutic intervention in cancer and metabolic diseases.

• Epigenetic mechanisms in human disease
• Novel epigenetic modifications and modulators
• Cancer epigenetics
• +۴ مورد دیگر

Dr. Shengjian Ji serves as Associate Professor with Tenure in the Department of Neuroscience at Southern University of Science and Technology's School of Life Sciences, concurrently holding the position of Associate Dean for Academic Affairs at Shude College. His laboratory is internationally recognized for pioneering research on mRNA modification mechanisms in neuronal development and function, with particular emphasis on posttranscriptional regulation in axons. Dr. Ji's academic foundation includes: Doctor of Science (Ph.D.) from Peking University (1998-2003) Bachelor of Science from Yantai University (1994-1998) His research program centers on mRNA modifications (m 5 C and m 6 A), local axonal translation, and retrograde signaling pathways critical for neuronal development. The lab employs advanced techniques including microfluidic axonal analysis and molecular neuroscience approaches to investigate how RNA-binding proteins regulate neurogenesis, axon guidance, and dendrite maintenance in cortical, retinal, and cerebellar systems. Analysis of Dr. Ji's 2018-2025 publications reveals a dominant focus on RNA epitranscriptomics in neural development, with emerging applications in aging and disease models. His work demonstrates how m 6 A and m 5 C modifications orchestrate local translation in axons through readers like YTHDFs and Ybx1, influencing processes from embryonic neurogenesis to age-related visual decline. Major recognitions include: National Natural Science Award of China, Second Prize (2011) Ministry of Education University Scientific Research Award, First Prize in Natural Science (2008) Peking University's Ten Most Academically Outstanding Graduate Students (2003) Dr. Ji actively mentors graduate students and postdoctoral researchers, with recent master's thesis defenses by Jiaxin Yuan and Pingrui Zhang. His laboratory maintains active funding evidenced by student Yu Jun's 2024 NSFC Young Scientists Fund award, and consistently recruits talent through SUSTech's postdoctoral and graduate programs. The lab currently investigates RNA modification mechanisms across multiple neural systems using cutting-edge molecular and bioengineering approaches, with ongoing projects spanning cortical development, retinal neurodegeneration, and axon guidance pathways.

• Developmental Neurobiology
• mRNA Modification
• Local mRNA Translation
• +۳ مورد دیگر