جستجوی استاد راهنمای دانشگاهی

Fabio Zanini is an Associate Professor at the University of New South Wales (UNSW) , leading a research group focused on computational biology , single-cell approaches , and transcriptomic analysis across diseases like severe dengue , neonatal lung disease , cancer , and marine biology . He previously conducted postdoctoral research at Stanford University (2016-2019) and earned a PhD in Bioinformatics from the Max Planck Institute for Developmental Biology and the University of Tuebingen (2015). Current Affiliation: Group leader, UNSW Previous Training: Postdoc (Stanford), PhD (Max Planck/University of Tuebingen) His research spans single-cell RNA sequencing , computational virology , developmental cell biology , and bioinformatics tool development , with recent work on: Severe dengue progression (viral-host interactions, immune signatures) Lung development (endothelial cell diversity, hyperoxia-induced injury) Cancer genomics (mutant HSC clones, AZA therapy response) Marine biology (plankton transcriptomics, evolutionary analysis) Bioinformatics (HTSeq 2.0, northstar algorithm) Recent scientific awards include grants from the Chan Zuckerberg Initiative ($270,000), NIH R01 (multiple), ARC Discovery Grant , and NHMRC Ideas Grant . Notable contributions include: Northstar - Cell classification algorithm SpectralSeq - Hyperspectral-transcriptomic integration Tabula Muris - Mouse aging atlas He has supervised research into hematopoietic stem cell regulation , lung vascular development , and autophagy in viral infections , with collaborations across Stanford , University of Sydney , and Harvard .

• Computational Biology
• Single-Cell RNA Sequencing
• Virology
• +۴ مورد دیگر

Professor Charlotte Kloft is Head of the Department of Clinical Pharmacy & Biochemistry at the Institute of Pharmacy, Free University of Berlin since 2011, and spokesperson for the interdisciplinary Graduate Research Training Program PharMetrX 'Pharmacometrics and Computational Disease Modelling' since 2008. She previously served as Professor and Head of the Department of Clinical Pharmacy at Martin-Luther-University Halle-Wittenberg (2005-2011) and as Scientific Assistant/Senior Assistant at Freie Universität Berlin (1999-2005). Her academic credentials include a habilitation in Clinical Pharmacy from Freie Universität Berlin (2003) and a Dr. rer. nat. (summa cum laude) from the same institution (1997). She earned her license as a pharmacist in 1992 after completing pharmacy studies at Johannes Gutenberg-University, Mainz (1987-1991). Professor Kloft's research focuses on pharmacometrics, computational disease modeling, and therapeutic drug monitoring across multiple therapeutic areas. Her work bridges pharmaceutical sciences with clinical practice, with particular emphasis on personalized dosing strategies for oncology, antimicrobial resistance, and inflammatory bowel diseases. She has pioneered research in optimizing drug dosing through pharmacokinetic/pharmacodynamic modeling, with applications in both antibiotic and cancer therapies. Her recent publications demonstrate a strong evolution toward integrating advanced computational approaches with clinical pharmacology, including machine learning applications in pharmacometrics, personalized dosing strategies for biologics during pregnancy, and developing nationwide infrastructure for therapeutic drug monitoring in cancer therapy through the ON-TARGET study. Academic Center of Excellence of Pharsight (now Certara), USA (since 2000) Habilitationsreisestipendium of Dr. August and Dr. Anni Lesmüller-Stiftung (2002) Ernst-Reuter-Preis of Ernst-Reuter-Gesellschaft (1998) Joachim-Tiburtius-Preis of Berlin Senate (1998) Young Investigator Award of EORTC-PAMM (1997) Professor Kloft has successfully supervised numerous doctoral students whose research spans diverse areas including CAR-T cell therapy, antimicrobial resistance, inflammatory bowel disease treatment optimization, and pharmacokinetic modeling of novel therapeutic agents. Her research group has secured significant funding for projects including GlobalResist, ON-TARGET, ABIMMUNE, COMBINATORIALS, and TAIN. She leads a vibrant research ecosystem at the Free University of Berlin with strong collaborations across Europe and internationally, maintaining state-of-the-art laboratory facilities including Biosafety Level 2 certified labs for infectious disease research.

• Pharmacometrics
• Computational Disease Modeling
• Therapeutic Drug Monitoring
• +۶ مورد دیگر

Dr. Kibret Mequanint is a full Professor at Western University's Department of Chemical and Biochemical Engineering, with cross-appointments in Biomedical Engineering. Holding a PhD from University of Stellenbosch and postdoctoral experience at Technical University of Darmstadt and McMaster University, his research bridges polymer science, materials engineering, and life sciences with applications in Biomaterials , Tissue Engineering , and Regenerative Medicine . His work spans both fundamental and translational research in cell-material interactions , polymer biomaterial design , and therapeutic radiation dosimeters , with technologies transferred to commercial applications. Leading scholar and educator with awards from NSERC, CIHR, and Western University Fellow of: American Institute for Medical and Biological Engineering (AIMBE), Ethiopian Academy of Sciences, International Union of Societies for Biomaterials Science and Engineering, Canadian Academy of Engineering Extensive editorial and panel service for NSERC, CIHR, and international journals His research program has produced over 170 refereed publications, focusing on conductive hydrogels , bioadhesives , and vascular tissue engineering . Recent work on endoscopy-deliverable bioadhesives and snake venom-derived hemostatic gels has attracted global media attention. He has served in leadership roles at the Canadian Biomaterials Society and university governance bodies including Senate and Board of Governors.

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +۶ مورد دیگر

Prof. Dr. Norbert Sewald, Chair of Organic and Bioorganic Chemistry at Bielefeld University, is a leading figure in Bioorganic Chemistry , Chemical Biology , and Enzymatic Halogenation . As head of the Organic and Bioorganic Chemistry Group at the Center for Biotechnology (CeBiTec), he drives research on natural products and drug conjugates. Full Professor, Bielefeld University (since 1999) Founding Coordinator, International Graduate School of Chemistry and Biochemistry (2001-2003) Chairman, Institute of Biochemistry and Bioengineering at CeBiTec (2006-2008) Dean, Department of Chemistry (2008-2011) Chairman, Max-Bergmann-Kreis e.V. (since 2010) Coordinator, Marie Skłodowska-Curie Training Networks (MAGICBULLET, 2015-2018; Magicbullet::reloaded, 2020-2023) His research focuses on halogenases for mild peptide bromination, cryptophycin-based tumor targeting , and bioactive natural products from African flora. Collaborative projects span antiplasmodial agents , antibacterial compounds , and neurodegenerative disease inhibitors . Recent work highlights include: Enzymatic halogenation cascades Click-to-release drug conjugates Fluorescent probes for amyloid detection Key affiliations: Faculty of Chemistry Center for Biotechnology (CeBiTec) European Peptide Society (Scientific Affairs Officer, 2016-) Leibniz Institute of Plant Biochemistry (Scientific Advisory Board, 2010-2017)

• Bioorganic Chemistry
• Chemical Biology
• Organic Chemistry
• +۵ مورد دیگر

Prof. Dr. Bart Jan Ravoo is a Professor of Organic Chemistry at the University of Münster, Germany, where he leads the "Synthesis of Nanoscale Systems" research group. He is also co-director of the Center for Soft Nanoscience (SoN) and spokesperson of the Collaborative Research Center (CRC 1459) "Intelligent Matter". His research focuses on creating novel nanoscale materials through supramolecular chemistry and molecular self-assembly. Prof. Ravoo received his PhD from the University of Groningen in 1998 and completed postdoctoral work at University College Dublin. He joined the University of Münster in 2007 as a professor, after serving as an assistant professor at the University of Twente. From 2012-2014, he served as Dean of the Department of Chemistry and Pharmacy. His research spans three main areas: biomimetic supramolecular chemistry, surface functionalization by molecular self-organization, and responsive materials. Prof. Ravoo's group is particularly known for developing photoresponsive materials using arylazopyrazoles and cyclodextrin-based systems for applications ranging from drug delivery to smart adhesives. His work often bridges the gap between fundamental molecular design and practical applications in biomedicine and materials science. Prof. Ravoo's recent publications demonstrate a strong focus on light-responsive materials, with particular emphasis on arylazopyrazole and arylazoisoxazole photoswitches. His research shows how molecular photoswitches can be integrated into various material systems including hydrogels, nanoparticles, and surface coatings to create materials with tunable properties that respond to specific wavelengths of light. This work has important implications for drug delivery, sensing, and adaptive materials. Recipient of the Schering-Plough Newman Scholarship in Organic Chemistry Member of the "Cells in Motion" research cluster Supervisor in the CiM-IMPRS Graduate Programme Prof. Ravoo has supervised over 40 PhD students and has been instrumental in establishing interdisciplinary research collaborations at the University of Münster. His group, consisting of approximately 25 researchers, is supported by multiple funding agencies including the Deutsche Forschungsgemeinschaft (DFG), European Union, and Volkswagen Foundation.

• Supramolecular Chemistry
• Self-Assembly
• Nanoscale Systems
• +۷ مورد دیگر

Dr. Shelley Wickham is an Associate Professor and ARC DECRA Fellow at the University of Sydney, holding joint appointments in the Schools of Chemistry and Physics. She serves as a Westpac Research Fellow and leads the DNA Nanotechnology Group at the Sydney Nano Institute. Dr. Wickham is also co-Champion of the Sydney Nano Institute Grand Challenge project in Molecular Nanorobotics for Health, co-lead of the School of Physics Grand Challenge on Nanoscale brain navigation for targeted drug delivery, and faculty mentor of the University of Sydney BIOMOD team. Bachelor of Science and Master of Science in Physics from University of Sydney PhD in Condensed Matter Physics from University of Oxford Postdoctoral Fellow at Harvard Medical School, Dana-Farber Cancer Institute, and Wyss Institute Dr. Wickham's research focuses on self-assembling nanotechnology and molecular robotics, particularly in the design and assembly of programmable nanostructures out of DNA. Her work spans applications in cell biology, materials science, and nanomedicine. Current research projects include design and synthesis of self-assembling DNA nanostructures, proto-cells made of DNA gels that move under flow, new plasma fabrication methods for biomolecule micropatterning, and DNA computation circuits for navigating the brain using machine learning. Her research aligns with the Faculty of Science Research Strengths in Molecules to Materials, Preventing and Treating Disease & Disorder, and Next Generation Materials. Analysis of Dr. Wickham's recent publications reveals a consistent focus on DNA nanotechnology with increasing sophistication in structural complexity and biological applications. Her work has evolved from fundamental DNA origami structures to increasingly complex multi-component systems with practical applications in nanomedicine and biomimetic engineering. Recent publications show strong interdisciplinary collaboration across chemistry, physics, biology, and engineering disciplines, with emphasis on real-world applications including drug delivery systems and biomolecular sensors. ARC DECRA Fellow Westpac Research Fellow BIOMOD World Champions (2019) Dr. Wickham actively mentors PhD students and postdoctoral researchers in her DNA nanotechnology group. She has secured significant research funding including ARC Discovery Projects, Westpac Scholarships, and NSW Health grants. Her current grants support projects such as '3D Bio-Nanomaterial Displays with Designer Architectures and Functions' and 'RNA aptamer sensing devices for rapid detection of blood clotting.' Dr. Wickham encourages applications from diverse backgrounds and maintains active collaborations with researchers at Harvard, Oxford, and other international institutions. Dr. Wickham leads the DNA Nanotechnology Group at the University of Sydney, which is part of the Sydney Nano Institute. Her lab focuses on building tools from DNA origami - including tweezers, spanners, wrenches and springs - to better understand biological processes at the nanoscale. The group has achieved notable success with the BIOMOD team winning world championships in 2019, and continues to develop innovative approaches to molecular robotics for healthcare applications.

• DNA Nanotechnology
• Molecular Robotics
• Self-Assembling Nanostructures
• +۴ مورد دیگر

Justin English serves as Assistant Professor of Biochemistry at the University of Utah School of Medicine, where he develops molecular tools to investigate human health and disease mechanisms through directed evolution and protein engineering approaches. Education: B.A. from Cornell University Ph.D. from University of North Carolina at Chapel Hill Research Focus: Dr. English's laboratory specializes in Directed Evolution and Protein Engineering to create molecular tools for studying G-protein Coupled Receptors (GPCRs) , cell signaling pathways , and neuroscience applications . His work integrates synthetic biology with classical pharmacology to develop innovative platforms like VEGAS for mammalian cell evolution and TRUPATH for GPCR transducerome analysis, with significant implications for drug discovery and therapeutic development. Publication Trends: Analysis of his 2019-2025 publications reveals consistent focus on GPCR biology, featuring breakthroughs in biosensor development (nanobody-based receptor monitoring), chemogenetic tools (BioTAC system), and high-throughput screening platforms. His research demonstrates strong translational potential in neuroscience, particularly through engineered mouse models for psychedelic drug studies and molecular tools for mapping small-molecule interactomes. Research Environment: Dr. English leads an active laboratory within the University of Utah's Department of Biochemistry, leveraging institutional core facilities for biochemical and molecular studies. His research program maintains strong collaborative ties with neuroscience and pharmacology groups, with ongoing projects focused on advancing molecular engineering techniques for biomedical applications as detailed on his lab website.

• Directed Evolution
• Protein Engineering
• Molecular Tool Development
• +۵ مورد دیگر

Jennifer Golden is an Associate Professor in the Department of Pharmaceutical Sciences at the School of Pharmacy , University of Wisconsin-Madison . Her research focuses on synthetic medicinal chemistry to develop novel antiviral and anti-parasitic agents for diseases like alphavirus infections and kinetoplastid parasites. The Golden Lab emphasizes chemical methodology development and structure-activity relationship analysis through collaborations assessing compound efficacy in cell and animal models . Research Projects Quinazolinone Rearrangement: Developing synthetic transformations for amidine formation and ring-fused scaffolds. Anti-Alphaviral Agents: Creating FDA-approved therapeutic candidates for mosquito-borne RNA viruses. Broad-Spectrum Antiparasitics: Optimizing compounds for malaria, African sleeping sickness, and leishmaniasis. Publications highlight her work on ML336 (anti-VEEV), quinazolinone derivatives , and collaborations with experts in high-throughput screening and structural biology . Her lab trains students in hit-to-lead optimization , regioselective synthesis , and medicinal chemistry tactics . Education: B.S. (1996) – Eastern Illinois University Ph.D. (2002) – University of Kansas Postdoctoral Research (2004) – Stanford University

• Synthetic Medicinal Chemistry
• Antiviral Drug Development
• Antiparasitic Drug Discovery
• +۳ مورد دیگر

David J. Brenner serves as Higgins Professor of Radiation Biophysics in Radiation Oncology and Environmental Health Sciences at Columbia University Medical Center. He directs both the century-old Center for Radiological Research and the Radiological Research Accelerator Facility (RARAF), leading interdisciplinary teams focused on radiation applications in medicine and safety. BA in Physics from Oxford University (1974) MSc in Radiation Physics from University of London (1976) MA in Physics Philosophy from Oxford University (1979) PhD in Physics from University of Surrey (1980) His research spans dual aspects of radiation: therapeutic applications in cancer treatment and risk assessment across diverse scenarios. Key initiatives include advancing carbon-ion therapy for pancreatic cancer, developing safe far-UVC light for pathogen elimination, and investigating low-dose radiation risks from medical imaging to nuclear terrorism. His team leverages RARAF's unique capabilities for mechanistic studies of radiation effects. Publications reveal dominant themes in radiation biophysics, with significant contributions to biodosimetry (RABiT platform), UV disinfection technology, and cancer risk modeling. Recent work emphasizes translational applications including medical countermeasures for radiation exposure and precision radiation oncology techniques. National Academy of Sciences Nuclear and Radiation Studies Board member National Council on Radiation Protection and Measurements member Radiation Research Society Failla Gold Medal recipient (2011) Oxford University Weldon Prize for mathematical biology (2015) Robert D. Moseley Award for Radiation Protection in Medicine Brenner leads multiple NIH-funded projects including biodosimetry development and UV disinfection research. His mentorship extends through directing Columbia's Radiological Research Accelerator Facility and training programs in radiological sciences. Current lab efforts focus on carbon-ion therapy mechanisms and 222-nm UV applications against drug-resistant pathogens, with active collaborations across oncology, microbiology, and physics disciplines.

• Radiation Biophysics
• Cancer Radiotherapy
• Ionizing Radiation Effects
• +۴ مورد دیگر

Amber Martin, Pharm.D., BCPS, is an Associate Clinical Professor at Auburn University Harrison College of Pharmacy. Her professional address is 1330p Walker Building, Auburn, AL 36849, and she can be reached at martiam@auburn.edu. Education: Pharm.D., Auburn University Harrison College of Pharmacy, 2007 Dr. Martin specializes in geriatric pharmacotherapy, COPD management, diabetes treatment, and medication regimen reviews for skilled nursing facilities. She integrates sterile compounding education into the curriculum and coordinates skills laboratory experiences for pharmacy students. Her research focuses on age-related medication challenges, chronic disease management, and interdisciplinary clinical education. She has presented nationally on topics such as diabetes care, geriatric pharmacotherapy, and inhaler techniques for elderly COPD patients, with publications in journals like Current Pharmacy Teaching and Learning and Expert Review of Clinical Pharmacology . Dr. Martin contributes to experiential education through introductory and advanced pharmacy practice experiences (IPPEs/APPEs) and PGY-1 residency training. She collaborates with multidisciplinary teams at East Alabama Medical Center and has delivered regional continuing education lectures on COPD, vitamin D, and GI therapies.

• Geriatric Pharmacy
• Clinical Pharmacotherapy
• Medication Management
• +۶ مورد دیگر

Anne Staples is an Associate Professor in the Department of Mechanical Engineering at Virginia Tech, leading the Laboratory for Fluid Dynamics in Nature (FINLAB). Her research focuses on fluid mechanics in biological systems, medical fluid dynamics, and bioinspired engineering, leveraging computational modeling and microfluidic technologies to innovate in healthcare and engineering. Education: B.S. in Mechanical and Aerospace Engineering, Cornell University (2000) M.Eng. in Mechanical and Aerospace Engineering, Princeton University (2001) Ph.D. in Mechanical and Aerospace Engineering, Princeton University (2006) Postdoctoral Researcher at the Naval Research Laboratory (2006–2008) Research Interests: Her work spans bioinspired microfluidics, medical device design, and fluid dynamics in biological systems. Notable projects include developing pulse-driven micropumps for drug delivery and studying insect respiratory systems to inform engineering solutions. Publications: Over 50 peer-reviewed articles, focusing on topics like microfluidic systems, insect-inspired flow control, and hemodialyzer modeling. Recent work emphasizes wearable drug delivery and biomechanical innovations. Awards & Service: NIH Trailblazer Award (2024) Virginia Tech Dean’s Fellow (2023–present) Editorial Board Member, PLOS ONE and Scientific Reports (2021–present) Fulbright Scholar (2016) Grants & Collaborations: Leads a NIH-funded project to develop lightweight drug delivery devices. Collaborates with statisticians and biomedical engineers to simulate and optimize prototypes. Active in interdisciplinary teams at Virginia Tech and Georgia Tech. Labs & Teams: Directs the FINLAB, which integrates computational modeling, experimental microfluidics, and biological principles to address challenges in healthcare and environmental engineering.

• Bio-Inspired Engineering
• Fluid Dynamics
• Medical Devices
• +۶ مورد دیگر

Professor Steven V. Ley leads the Yusuf Hamied Department of Chemistry at the University of Cambridge, focusing on transformative research in flow chemistry, organic synthesis, and green chemistry. His work emphasizes sustainable methodologies and the integration of advanced technologies like microcontrollers and automation to revolutionize chemical processes. In 2018, he received the prestigious Arthur C. Cope Award—the first UK-based recipient—recognizing groundbreaking contributions to organic chemistry. Research interests include developing continuous flow systems for hazardous reaction management, immobilized reagents, and machine-assisted synthesis. Collaborations span academia and industry, notably through spin-off company New Path Molecular , which applies cutting-edge synthesis techniques to pharmaceuticals and agrochemicals. Key publications highlight innovations in flow chemistry applications, sustainable process design, and automation. His work bridges chemistry with engineering, aiming to address global challenges in resource efficiency and environmental impact. Awards: Arthur C. Cope Award (2018) Lab/Teams: Active research group at the University of Cambridge; collaborates with New Path Molecular on commercial applications.

• Organic Chemistry
• Flow Chemistry
• Green Chemistry
• +۴ مورد دیگر

Gerald Quon is an Associate Professor in the Department of Molecular and Cellular Biology at the University of California, Davis. He is affiliated with the Genome Center and participates in multiple graduate programs, including Integrative Genetics and Genomics, Neuroscience, Computer Science, Biostatistics, and Biomedical Engineering. Education: PhD in Computer Science from the University of Toronto (2012) MSc in Biochemistry from the University of Toronto (2006) Research Interests: Dr. Quon applies computational approaches to genetics and genomics problems, focusing on the genetics of human disease , models of cell population dynamics , and neurogenomics . His lab builds neural network models to understand how genetic variation affects disease risk through molecular and cellular phenotypes, with applications to obesity, Alzheimer’s disease, psychiatric disorders, and Rett syndrome. Recent Research Trends: Recent publications highlight work in neuroplasticity , single-cell multimodal analysis , brain evolution , morphological variation modeling , and microbiome-based classification . His team combines sequencing and imaging technologies to model cellular interactions and gene expression dynamics. Scientific Awards: NIH New Innovator Award (2021) Grants & Collaborations: He received NSF funding (2019) for computational tools in single-cell analysis and collaborates across disciplines, including neuroscience, biomedical engineering, and computational biology. His lab develops software like scProjection , siVAE , and scAlign .

• Computational Biology
• Single Cell Genomics
• Epigenomics
• +۵ مورد دیگر

Dr. Scott Lovell is a Senior Lecturer in Chemical Biology at the University of Bath's Department of Life Sciences. He leads the Lovell Group researching covalent drug discovery at the chemistry-biology-medicine interface, focusing on cancer and antibiotic-resistant infections. His team specializes in peptide synthesis, chemical proteomics, and phage display technologies. Dr. Lovell's research interests include: Covalent phage display for undruggable proteins Targeted covalent macrocycles (TCMs) Protease-activated imaging agents Covalent fragment libraries for cancer treatment His recent publications demonstrate a focus on developing covalent inhibitors through innovative screening platforms, with applications spanning transcription factor inhibition, antimicrobial strategies, and peptide-based drug discovery. Research strongly emphasizes translational approaches combining synthetic chemistry with molecular biology. Dr. Lovell is currently PI on multiple funded projects including: Tackling the Undruggable Cancer Proteome with Covalent Macrocycles (EPSRC) Synthesis of Targeted Covalent Macrocycle Libraries (Royal Society) A Phage Display Approach for Undruggable Proteins (Academy of Medical Sciences) He welcomes doctoral students to his interdisciplinary research team investigating novel chemical modalities for disease treatment.

• Chemical Biology
• Drug Discovery
• Chemical Proteomics
• +۵ مورد دیگر

Jan C.M. van Hest is a Full Professor at Eindhoven University of Technology (TU/e), holding positions in the Department of Chemical Engineering and Chemistry and the Institute for Complex Molecular Systems (ICMS) . He leads research at the intersection of polymer chemistry and biomedicine, focusing on bio-inspired materials, nanomedicine, and artificial cells. His work includes developing synthetic vaccines, drug delivery systems, and adaptive nano/microcompartments mimicking cellular functions. Academic Background : Ph.D. in macro-organic chemistry from TU/e (1996), postdoc at the University of Massachusetts (protein engineering), and industry roles at DSM (1997–2000). Since 2016, he has held the Bio-organic Chemistry chair at TU/e, supervising over 30 PhD students and co-founding startups like Encapson and Noviosense. Research Highlights : His research spans nanomedicine (e.g., polymersomes for cancer treatment) and artificial cells (e.g., synthetic organelles). Recent work includes therapeutic nanovaccines and self-propelled platinum-loaded stomatocytes. His publications span Nature Nanotechnology , Nature Chemistry , and Angewandte Chemie . Awards & Collaborations : Recipient of the ERC Advanced Grant (2015) and NWO Gravitation Grant (2013). Partnerships with GSK, Zoetis, and industry initiatives like the TKI-LSH EUREKA project. Engages in education through courses like Biochemistry and Introduction to Chemistry & Chemical Technology. Labs & Teams : Core member of ICMS, leading interdisciplinary projects in functional molecular systems. Active in training the next generation of researchers through postgraduate programs like ICMS PTN.

• Bio-inspired Materials
• Nanomedicine
• Artificial Cells
• +۳ مورد دیگر