جستجوی استاد راهنمای دانشگاهی

Robert Lindroos is a Research Fellow at KTH Royal Institute of Technology, specializing in computational neuroscience and brain-inspired computing. He transitioned from a culinary background to academia, earning degrees in civil engineering, engineering physics (KTH), and a PhD in neuroscience (Karolinska Institutet). His research focuses on understanding neural mechanisms underlying cognition, particularly in olfactory processing and Parkinson's disease, conducted within the dBRAIN and Digital Futures initiatives. Key research interests include computational models of basal ganglia circuits, neuromodulation effects (dopamine/choline), and age-related sensory decline. Lindroos has explored odor identification deficits, synaptic plasticity in spiny projection neurons, and the neurocomputational basis of perceptual errors. His work bridges engineering principles with biological systems, aiming to develop brain-like computing paradigms. Publications span computational neuroscience (2011–2025), with recent emphasis on olfactory system modeling and neuromodulatory dynamics. His early work included lunar communication system design, showcasing interdisciplinary technical expertise. Lindroos collaborates with dBRAIN and Digital Futures at KTH, advancing computational approaches to neurological disorders and neural network simulation.

• Neuroscience
• Computational Neuroscience
• Neural Networks
• +۳ مورد دیگر

Tom Erkers is an Assistant Professor at the Department of Oncology-Pathology, Karolinska Institutet, leading the Functional Systems Oncology team. His research focuses on functional precision medicine and molecular profiling in blood cancers, particularly acute myeloid leukemia (AML) and pediatric acute lymphoblastic leukemia (ALL). University: Karolinska Institutet Department: Department of Oncology-Pathology Academic Rank: Assistant Professor (2020-2024) Research Interests: His work explores cancer cell behavior, treatment resistance, and immune interactions in hematologic malignancies. Key areas include: Functional precision medicine (fPM) Multi-omics integration for therapeutic targets Drug synergy prediction models Radiotherapy and autophagy inhibition strategies Immune tolerance mechanisms in transplantation Publications Trends: Recent articles emphasize: Ex vivo sample handling impacts on precision medicine reliability Computational models for drug combinations in AML Targeting SAMHD1 and BCLxL in leukemia iNKT cell heterogeneity in autoimmune contexts Molecular hallmarks of hematologic cancers Team Members: Collaborators include PhD students Lucía Rico Pizarro and Nona Struyf, postdoctoral researcher Flora Mikaeloff, and multidisciplinary scientists across the Kallioniemi group.

• Cancer Research
• Precision Medicine
• Hematology
• +۳ مورد دیگر

Federico Pietrocola is a Principal Researcher at the Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm. He leads the Cellular Stress in Health and Disease research group, focusing on molecular mechanisms linking cellular senescence, autophagy, and aging pathologies. His work bridges basic science with translational applications in cancer, metabolic disorders, and fibrotic diseases. His research investigates cellular senescence as a driver of age-related pathologies and autophagy as a protective mechanism. Key areas include: Senescence-induced fibrosis in lung and kidney diseases Immunogenic properties of senescent cells in cancer immunity Polyamine metabolism (e.g., spermidine) in longevity Metabolomic regulation of stress responses Senolytic drug development targeting ACBP/DBI and COPI pathways Analysis of recent publications (2023-2025) reveals a dominant focus on senescence-immune interactions and metabolism-targeted therapies . His group pioneered senolytic screening methods and demonstrated how senescent cells trigger lung fibrosis in humanized models. Strong emphasis on translating findings into treatments for fatty liver disease, chronic kidney disease, and cancer via autophagy modulation. Scientific Awards: No awards listed in provided profile information Dr. Pietrocola currently directs a major Swedish Research Council grant (2024-2027) for senescence-targeted cancer immunotherapy. He secured consecutive Novo Nordisk Foundation grants (2021-2023) targeting polyamine metabolism in senescence-related disorders. His earlier project (2020-2023) explored immune checkpoint therapies against aging pathologies. While specific students aren't named, his publications indicate active mentorship through collaborative projects. His Cellular Stress in Health and Disease group develops innovative models including humanized pulmonary fibrosis systems and metabolomic platforms for single-cell analysis. Current work emphasizes senescence-specific immune checkpoints, microvascular aging in kidney disease, and polyamine-based interventions to counteract tissue degeneration across multiple disease contexts.

• Cellular Senescence
• Autophagy
• Aging
• +۱۲ مورد دیگر

David Balgoma is a Researcher at Uppsala University's Department of Medicinal Chemistry; Analytical Pharmaceutical Chemistry, specializing in lipidomics and metabolomics with advanced analytical chemistry methodology development. His work integrates mass spectrometry, chromatography, and computational approaches to address biomedical challenges. His research focuses on: Lipid metabolism alterations in liver cancer and response to chemotherapeutics (e.g., doxorubicin) Development of novel analytical techniques for lipid separation and characterization Role of lipids in viral infections and deep-sea organism physiology Engineering ROS-sensitive biomaterials for wound healing applications Analysis of his 2022-2024 publications reveals consistent innovation in analytical methodology (chromatographic optimization, peak characterization algorithms) coupled with biological insights into lipid pathways in disease. His interdisciplinary approach bridges analytical chemistry, oncology, and biomaterials science, frequently appearing in high-impact journals like Analytica Chimica Acta and Molecular Metabolism.

• Lipidomics
• Metabolomics
• Analytical Chemistry
• +۳ مورد دیگر

Johan Gising is a Researcher at Uppsala University, affiliated with both the Department of Materials Science and Engineering (Nanotechnology and Functional Materials) and the Department of Medicinal Chemistry (Preparative Medicinal Chemistry). His work spans interdisciplinary domains of medicinal chemistry, organic synthesis, and sustainable materials. Email: johan.gising@angstrom.uu.se, johan.gising@ilk.uu.se Contact: Ångströmlaboratoriet, Uppsala Biomedicinska Centrum Research Interests include: Design and synthesis of enzyme inhibitors for infectious diseases (Hepatitis C, HIV, Tuberculosis) Development of green chemistry methods (microwave-assisted synthesis, biomass fractionation) Materials science applications (lignin-based electrochemical storage, IRAP inhibitors for cognition) Pharmacological studies on AT2 receptor ligands and neuronal health Patents and Collaborations highlight his contributions to functionalized lignin applications and the European antibacterial drug discovery initiative ENABLE . His recent 2025 conference papers focus on biomass utilization for sustainable solutions.

• Medicinal Chemistry
• Organic Chemistry
• Drug Discovery
• +۵ مورد دیگر

Mattias Magnusson is an Associate Professor at Lund University's Division of Molecular Medicine and Gene Therapy, serving as Principal Investigator in StemTherapy and LUCC (Lund University Cancer Centre). He leads the Stem Cell and Cancer Stem Cell Regulation research team and focuses on hematopoietic stem cells, lung disease, and regenerative therapies. Research interests: Stem cell biology and niche regulation Lung cancer and fibrosis mechanisms Molecular pathways in hematopoiesis Translational applications in regenerative medicine Recent trends from his 15 most recent publications include proteomic mapping of plasma dynamics, environmental sensing in stem cells via MYCT1, and molecular targets in lung squamous cell carcinoma. His work bridges fundamental discoveries in stem cell regulation with clinical applications in leukemia and pulmonary diseases. Notable activities: Organized UniStem Day 2024 Speaker at LUCC Lung Cancer Meeting 2022

• Stem Cell Research
• Cancer Biology
• Molecular Medicine
• +۵ مورد دیگر

Lina Emilsson serves as Senior Lecturer in the Department of Game Design at Uppsala University's Campus Gotland. Her academic work integrates game design methodology with neuroscience to develop applications for project management training, neurorehabilitation protocols, and educational innovation in higher learning environments. She teaches core courses in game development, project leadership, and product development while maintaining an active research profile. Her research centers on decoding neural circuits of playfulness and translating these insights through game design principles. Key investigations include technology-assisted rehabilitation systems leveraging neurobiological and genetic frameworks, alongside creativity-enhancing frameworks for organizational leadership. This interdisciplinary approach bridges computational design with clinical neuroscience to address challenges in cognitive rehabilitation and educational engagement. Analysis of her 15 most recent publications (2009-2017) reveals consistent focus on molecular neuroscience mechanisms in neuropsychiatric disorders. Dominant themes include RNA-binding protein functions (particularly QKI) in schizophrenia and Alzheimer's pathology, vesicular transporter dynamics (VGLUT2, SLC10A4) in neurotransmission and behavior, and zebrafish-based neural development modeling. Her work demonstrates strong translational emphasis on biomarker discovery and therapeutic target identification. No scientific awards or fellowships were documented in the provided materials. The available information does not specify graduate student mentorship activities or externally funded research grants. Her academic role appears centered on teaching responsibilities within the Department of Game Design and independent research initiatives. No dedicated laboratory facilities or structured research teams were mentioned in the source documentation.

• Game Design
• Neurorehabilitation
• Project Management
• +۵ مورد دیگر

Stefanos Stagkourakis is an Assistant Professor in Molecular Life Science at Karolinska Institutet and a SciLifeLab Fellow 2024. He leads the Stagkourakis Lab, which sits at the intersection of Karolinska Institutet’s Department of Neuroscience and SciLifeLab. His research focuses on neural and neurohormonal mechanisms governing evolutionarily conserved survival behaviors like aggression, fear, parental care, and metabolic responses. Academic Rank: Assistant Professor Institution: Karolinska Institutet Collaboration: SciLifeLab (Sweden’s national hub for data-driven life science) His work employs advanced in vivo techniques including large-scale electrophysiology, multi-color biosensor imaging with miniscopes, and two-photon microscopy to study brain-wide computations in freely moving mice. Key interests include stimulus-specific hypothalamic encoding, experience-dependent plasticity, and hormonal state influences on circuit dynamics, particularly testosterone and oxytocin. The lab’s publication trends include mapping neural nodes critical to instincts, analyzing mesoscale hypothalamic representations, and investigating dysregulated circuits in neuropsychiatric contexts like anxiety disorders and metabolic dysfunctions. Recent work explores dopamine systems, electrical coupling rules, and cerebellar motor learning mechanisms. Scientific recognition includes the SciLifeLab Fellowship , supporting his lab’s mission to bridge molecular, cellular, and systems neuroscience. The team integrates computational and experimental expertise, with ongoing recruitment for researchers in neuroscience, engineering, and computational biology.

• Survival behaviors
• Neural circuits
• Instinctual behaviors
• +۴ مورد دیگر

Mika Gustafsson is a Professor in Bioinformatics at Linköping University's Department of Physics, Chemistry and Biology (IFM). His research focuses on integrating machine learning and bioinformatics to analyze biological data for precision medicine applications, particularly in immunology and neurology. He leads projects on epigenetic signatures, disease module discovery, and AI-driven biomarker identification. Key research interests include DNA methylation dynamics in diseases like tuberculosis and multiple sclerosis, T-cell immunology during pregnancy, and the development of computational tools such as scDrugPrio and MODalyseR for precision medicine. His work has led to grants from the Swedish Research Council (VR) and collaborations on digital twins for personalized healthcare. Notable contributions include predicting disease severity in multiple sclerosis using machine learning and identifying biomarkers for tuberculosis via buccal swab analysis. He actively publishes in high-impact journals and contributes to translational bioinformatics through the Bioinformatics division at Linköping University.

• Bioinformatics
• Precision Medicine
• Epigenetics
• +۳ مورد دیگر

Elin Good is a researcher affiliated with the Department of Health, Medicine and Caring Sciences at Linköping University, within the Faculty of Medicine and Health Sciences. Her primary research focus is atherosclerosis, combining clinical work at the Cardiology Clinic in Linköping with interdisciplinary cardiovascular research. She is part of the Cardiovascular Imaging and Modeling (CIM) research cluster, which develops advanced imaging techniques such as MRI for plaque assessment and hemodynamic analysis. Elin collaborates on major studies like SCAPIS (Swedish CArdioPulmonary bioImage Study) and the LSH study (Life conditions, Stress and Health), investigating socio-economic and psychosocial factors influencing cardiovascular outcomes. Her research interests include cardiovascular imaging technologies (MRI, CT), biomarker development, and translational applications of imaging in clinical settings. She has contributed to studies on plaque vulnerability mechanisms, pandemic impacts on lifestyle behaviors, and diagnostic software innovations for myocardial perfusion imaging. Elin holds a 2015 Young Investigator Award from EuroPrevent Congress, recognizing her early career contributions. She participates in the Center for Medical Image Science and Visualization (CMIV), a hub for cutting-edge imaging research. Her work emphasizes bridging clinical needs with technological advancements, including photon-counting CT and deep learning algorithms for improved diagnostic accuracy.

• Atherosclerosis
• Cardiovascular Imaging
• Magnetic Resonance Imaging (MRI)
• +۳ مورد دیگر

Göran Engberg is a Professor at the Department of Physiology and Pharmacology at Karolinska Institutet. He leads the Electrophysiological Neuropharmacology research group, focusing on neuropharmacological mechanisms underlying neuropsychiatric disorders. His work centers on kynurenic acid’s role in schizophrenia pathogenesis, particularly its interaction with glutamate receptors and immune system activation. His research integrates electrophysiology, molecular biology, and translational studies to explore how immune-mediated kynurenine pathway dysregulation contributes to psychosis. Collaborations include SciLifeLab for drug development targeting kynurenic acid levels. Engberg’s lab also investigates neurodevelopmental models, such as social isolation effects on rodent sensorimotor gating, linking immune activation to schizophrenia-like behaviors. Key projects examine CSF biomarkers (e.g., neurogranin, complement proteins) in psychosis, cytokine signaling pathways, and genetic influences on kynurenine metabolism. Engberg’s studies highlight interdisciplinary approaches, combining preclinical models with clinical data from first-episode psychosis cohorts. His lab’s facilities include electrophysiological setups, microdialysis systems, and advanced proteomic/metabolomic analyses. Engberg maintains active roles in academic leadership, contributing to departmental strategic planning and training early-career researchers in neuropharmacology and translational neuroscience.

• Neurosciences
• Psychiatry
• Pharmacology
• +۴ مورد دیگر

Anders Gustafsson is a Senior Professor of Periodontology at the Department of Dental Medicine, Karolinska Institutet. He holds a dual role as Professor/Senior Dentist and has served in prominent administrative positions, including Vice President for Research (2019–2023), Dean of Research (2016–2019), and Dean of Doctoral Education (2012–2016). He earned both his dental and doctoral degrees from Karolinska Institutet, becoming a professor in 2005. His research focuses on the pathogenesis of periodontitis and its systemic implications, particularly cardiovascular disease and diabetes, with over 120 scientific articles in periodontology and inflammation. He has taught dental and dental hygiene students for over 35 years and supervised numerous graduate students. His work emphasizes translational research, exploring the bidirectional links between oral and systemic health. Recent studies include clinical trials on peri-implantitis treatments and longitudinal analyses of periodontitis-cardiovascular disease associations. He leads the PAROKRANK cohort study, investigating inflammatory biomarkers and comorbid conditions. His administrative roles have advanced institutional research policies and doctoral education frameworks. Research interests span periodontal inflammation mechanisms, systemic disease correlations, and treatment efficacy. Key topics include matrix metalloproteinases, cytokine networks, and the role of lifestyle factors like fasting. He collaborates internationally, such as in Rwanda on pre-eclampsia links. His contributions bridge clinical practice and basic science, influencing global dental and medical guidelines. Awards and honors are not explicitly listed, but his leadership roles reflect institutional recognition. He actively participates in academic advocacy, including Pride initiatives at Karolinska Institutet.

• Periodontology
• Cardiovascular Disease
• Diabetes
• +۳ مورد دیگر

Jenny Mjösberg is a Professor of Tissue Immunology at Karolinska Institutet's Department of Medicine, Huddinge. She leads the Human innate lymphoid cell lab, focusing on innate lymphoid cells (ILCs) in intestinal inflammation, cancer, and asthma. Her research integrates clinical and translational approaches, using single-cell technologies to dissect immune responses in barrier tissues like the gut and lungs. Education: BSc in biomedical chemistry from Kalmar University (2003), PhD in clinical immunology from Linköping University (2010), postdoc at University of Amsterdam (2010-2012), and established her independent group at Karolinska Institutet in 2014. Part-time lecturer at Linköping University until 2019. Research interests include ILC biology, tumor immunity, asthma mechanisms, and metabolic influences on immune cells. Key projects involve single-cell analysis of intestinal lymphocytes in IBD, ILC heterogeneity in colorectal cancer, and asthma biomarker identification in obese patients. Grants/awards: Swedish Research Council Consolidator Grant (2019), ERC Starting Grant (2020), KI Consolidator Grant (2022), Göran Gustafsson Prize (2023), Heart-Lung Foundation grant (2024). Active collaborations with clinicians and researchers across immunology, oncology, and respiratory medicine. Lab: Human innate lymphoid cell lab (Mjösberg Group) focuses on translational immunology, with projects in CLARU (Clinical Lung and Allergy Research Unit). Notable studies include defining ILC roles in pediatric colitis and linking host metabolism to asthma severity.

• Immunology
• Gastroenterology
• Infectious Medicine
• +۳ مورد دیگر

Pär Nordlund is a Professor at the Department of Oncology-Pathology, Karolinska Institutet. His research focuses on understanding cancer processes through protein-centric strategies, particularly using the Cellular Thermal Shift Assay (CETSA). CETSA enables in situ monitoring of protein-drug interactions and has been applied to study cancer mechanisms, drug resistance, and target engagement. Nordlund's lab explores protein interactions in cancer cells, tumor-associated immune cells, and immune-oncology processes to identify novel drug targets and biomarkers for personalized therapy. Key projects include developing CETSA as a tool for drug discovery and studying resistance mechanisms to improve cancer treatments. Research Interests : Proteomics, cancer biology, drug target validation, immune-oncology, biomarker development. Grants : Funding from Barncancerfonden, Cancerfonden, Knut och Alice Wallenberg Foundation, and the Swedish Research Council. His work bridges basic science and clinical applications, aiming to translate proteomic insights into clinical biomarkers and therapeutic strategies. The group collaborates on projects involving drug resistance, immune-tumor interactions, and advanced CETSA methodologies.

• Cancer and Oncology
• Cell and Molecular Biology
• Pharmacology and Toxicology
• +۳ مورد دیگر

Professor Tomas Björklund is a faculty member at Lund University, affiliated with the Faculty of Engineering (LTH) and the MultiPark research initiative focused on Parkinson's disease. His research integrates molecular biology, biotechnology, and advanced machine learning to develop therapies for neurological disorders, particularly Parkinson's disease and glioblastomas. He leads projects such as BainSPACE and NSC-Reconstruct, aiming to translate research into clinical applications through partnerships with biotech companies and pharmaceutical industries. He has founded four biotech companies and actively collaborates on projects funded by organizations like Hjärnfonden and the European Commission's Horizon 2020. His work emphasizes spatial sequencing, stem cell organoids, and engineered AAV vectors tailored for precise cellular targeting. He advocates for entrepreneurship to accelerate therapy development, ensuring research outcomes reach clinical settings efficiently. His research aligns with UN Sustainable Development Goals, particularly in advancing health and well-being. Björklund oversees a dynamic research group that combines invention, interdisciplinary collaboration, and translational medicine. His contributions include pioneering spatial sequencing and viral vector engineering, with 52 publications and five active or recent projects. He mentors students in cutting-edge methodologies and drives initiatives to map neural circuits and improve gene therapy efficacy.

• Gene Therapy
• Parkinson's Disease
• Molecular Biology
• +۴ مورد دیگر