جست‌وجوی استاد و پژوهشگر

• Signal Transduction
• Mitogen-Activated Protein Kinase (MAPK) Pathways
• Cell Polarity
• +۴ مورد دیگر

Paul J. Cullen, PhD, is a Professor in the Department of Biological Sciences at the University at Buffalo, College of Arts and Sciences. He has been recognized with the Distinguished Postdoctoral Mentor Award (2021-22), Milton Plesur Excellence in Teaching Award , and UB Exceptional Scholar — Sustained Achievement Award . Cullen serves as Director of Graduate Studies, emphasizing mentorship and academic development. Education: PhD in Biology, Washington University in St. Louis; BA in Biological Sciences, University of Illinois. Cullen’s research focuses on signal transduction pathways , particularly the Mitogen-Activated Protein Kinase (MAPK) pathways in budding yeast ( Saccharomyces cerevisiae ). His work investigates how cells sense environmental changes and relay signals via Cdc42-dependent MAPK networks to regulate cell polarity, differentiation, and stress response . Key studies include the role of mucin-type glycoproteins (e.g., Msb2) in MAPK activation, protein degradation mechanisms preserving signaling fidelity, and cross-pathway interactions causing disease when dysregulated. His lab employs genetic, biochemical, and bioinformatic approaches to dissect these processes. Recent publications highlight his team’s discoveries in MAPK pathway regulation through SEA domain analysis , gene-environment interactions , and chaperone-mediated protein turnover . These studies provide insights into fungal pathogenesis and eukaryotic signaling conservation . Scientific Awards: Distinguished Postdoctoral Mentor Award (2021-22) Milton Plesur Excellence in Teaching Award UB Exceptional Scholar — Sustained Achievement Award Cullen’s mentorship extends to postdoctoral scholars like Beatriz Gonzalez, who attributes her academic persistence to his guidance. His lab’s collaborative environment prioritizes career development and scientific passion , particularly for underrepresented researchers.

Abolfazl Avanمشاهده پروفایل

استاد مدعو

• Neuroepidemiology
• Brain Health
• Dementia
• +۷ مورد دیگر

Abolfazl Avan, MD, PhD, serves as an Adjunct Research Professor in Epidemiology and Biostatistics at Western University's Schulich School of Medicine & Dentistry and as a Research Associate at Robarts Research Institute's Dementia Prevention Initiative. He is a senior collaborator of the Global Burden of Disease Study and advises the WHO on dementia risk reduction guidelines. His academic credentials: MD, Tabriz University of Medical Sciences (2001-2009) MD Internships, Mashhad University of Medical Sciences (2007-2009) PhD, Amsterdam University Medical Center (2013-2015) Dr. Avan's research centers on neuroepidemiology and brain health , with particular emphasis on the global burden of neurological disorders including dementia, stroke, and ischemic heart disease. His work investigates modifiable risk factors and prevention strategies, spanning from Wilson's disease to socioeconomic and environmental determinants. He has contributed significantly to the Global Burden of Disease Study, especially in North Africa and the Middle East, and advocates for evidence-based interventions to improve brain health across the lifespan. Analysis of his recent publications reveals a focus on quantifying the burden of neurological disorders and developing practical frameworks for brain health measurement. He has led studies on secular trends showing decreasing incidence of stroke and dementia in some regions, highlighting prevention opportunities through risk factor modification. As a member of the American Academy of Neurology and active participant in international health initiatives, Dr. Avan bridges research with policy to promote brain health globally. His current work within Western University's Dementia Prevention Initiative explores modifiable risk factors and evidence-based interventions for cognitive decline.

Julie D. Forman-Kayمشاهده پروفایل

استاد

• Intrinsically Disordered Proteins
• Protein Dynamics
• CFTR Structure and Function
• +۵ مورد دیگر

Julie D. Forman-Kay is a Professor in the Department of Biochemistry at the University of Toronto and Program Head/Senior Scientist at the Molecular Medicine Program of the Research Institute of The Hospital for Sick Children. Her research focuses on the dynamic properties of proteins, particularly intrinsically disordered proteins (IDPs), and their functional roles in diseases like cystic fibrosis and neurological disorders. Her work integrates nuclear magnetic resonance (NMR) spectroscopy, computational modeling, and biophysical techniques to study protein structure, folding, and interactions. Key areas include phase separation of disordered proteins, post-translational modifications such as phosphorylation, and the structural dynamics of CFTR, the protein implicated in cystic fibrosis. The Forman-Kay lab has pioneered tools like the ENSEMBLE program for modeling disordered protein states and has made significant contributions to understanding dynamic complexes in ubiquitin ligases and translational regulation. Current projects explore RNA processing bodies, CFTR regulation, and the interplay between protein disorder and function. 2016–2023: Canada Research Chair in Intrinsically Disordered Proteins (Tier 1) 2013–2014: Zellers Senior Scientist Award 2012: CSMB Jeanne Manery Fisher Memorial Lectureship 2000–2005: CIHR Scientist Award 1999–2004: Ontario Premier’s Research Excellence Award 1994–1999: MRC of Canada Scholarship Julie Forman-Kay’s lab collaborates extensively with researchers such as Lewis Kay, Christine Bear, and Nahum Sonenberg. Her group trains graduate students and postdoctoral fellows in advanced techniques like NMR, fluorescence, ITC, and computational modeling. She co-chairs the CFTR Structure Consortium of the US Cystic Fibrosis Foundation Therapeutics.

Karl Grieshopمشاهده پروفایل

مدرس

• Evolutionary Genetics
• Genomics
• Bioinformatics
• +۱۲ مورد دیگر

Karl Grieshop is a Lecturer in Genomics and Bioinformatics at the School of Biological Sciences, University of East Anglia, where he also leads the Grieshop Lab. He is an active member of the Centre for Ecology, Evolution and Conservation and currently accepting PhD students through the ARIES DTP program. University: University of East Anglia School: School of Biological Sciences Position: Lecturer in Genomics and Bioinformatics Lab: grieshoplab.com Education and Career Background: Lecturer (2023–present), University of East Anglia Postdoctoral Fellow (2019–2023), University of Toronto & Stockholm University Ph.D., Uppsala University (2012–2017) M.S. and B.S., University of Cincinnati Karl Grieshop's research centers on evolutionary genetics, particularly the causes and consequences of genetic variation maintained through fitness trade-offs across sexes, environments, and life stages. His work integrates experimental evolution, quantitative genetics, genomics, and modeling in Drosophila melanogaster , with broader implications for conservation, pest management, and understanding genetic disease. His interdisciplinary approach spans lab experiments, bioinformatics, and mathematical modeling. His 15 most recent publications (with 5 most recent shown) demonstrate a strong focus on sexual conflict, dominance reversals, gene expression divergence, and the genomic architecture of adaptation. These studies frequently involve experimental evolution, transcriptomics, and population genetic simulations, often using Drosophila as a model system. Scientific Awards: Benzelius Award (2022) John Maynard Smith Prize (2019) Karl actively mentors students and collaborates internationally, with research extending to birds, plants, and other arthropods. He has been involved in securing PhD funding through the ARIES DTP and provides extensive training in Drosophila husbandry, bioinformatics, statistics, and scientific writing. His lab contributes significantly to understanding how genetic constraints shape evolutionary trajectories and adaptation in changing environments. Lab and Research Group: The Grieshop Lab (grieshoplab.com) conducts interdisciplinary research on evolutionary trade-offs, using experimental and computational approaches. The lab fosters collaboration and offers opportunities for postgraduate research in evolutionary genomics and adaptation.

Mathilde Boumasmoudمشاهده پروفایل

پژوهشگر

• Microbiology
• Antibiotic Resistance
• Pathogen Ecology
• +۳ مورد دیگر

Dr. Mathilde Boumasmoud is a Researcher in the Department of Environmental Systems Science at ETH Zurich, affiliated with the Professorship for Pathogen Ecology. Her work focuses on understanding microbial interactions, antibiotic resistance mechanisms, and pathogen behavior in clinical and environmental contexts. She has contributed to studies investigating the ecological dynamics of antibiotic-resistant bacteria in human microbiomes, outbreak investigations of multi-drug-resistant pathogens, and the molecular basis of bacterial persistence. Her research integrates genomic, ecological, and clinical approaches to address pressing issues in infectious disease, including necrotizing fasciitis caused by Group A Streptococcus and hospital-acquired infections like those caused by Pseudomonas aeruginosa. Boumasmoud has published extensively on topics such as bacterial adaptation, persister cell formation, and the application of advanced typing methods like FT-IR spectroscopy for outbreak analysis. Key contributions include demonstrating how ecological interactions within microbiomes influence antibiotic resistance spread and identifying genomic factors driving pathogen success in diverse environments. Her work bridges fundamental microbiology with translational applications in infection control and public health.

Donald F. Conradمشاهده پروفایل

دانشیار

• Human genetics
• DNA mutation
• Infertility
• +۴ مورد دیگر

Donald F. Conrad is an Associate Professor in the Department of Genetics at Washington University in St. Louis and serves as Chief of the Division of Genetics at the Primate Center at OHSU, where he was recruited in 2018. As a human geneticist with over 15 years of experience, Dr. Conrad has developed both statistical and experimental methods for genome analysis, with particular focus on male infertility and testis biology. Key research areas: Male infertility genetics Testis biology and spermatogenesis Genome biology of germ cells Single-cell genomics and RNA sequencing Development of computational tools for mutation detection (DeNovoGear) Development of automated image analysis tools for testis histology (SATINN) Analysis of postzygotic mutations in human tissues Based on recent publications, Dr. Conrad's research spans multiple areas of genetics with particular emphasis on male reproductive health. His work has led to the identification of novel genetic causes of male infertility and the development of computational tools to analyze these genetic phenomena. Scientific awards: Fulbright Specialist Grant (2017) Finalist for Postdoctoral Trainee (Basic) award, ASHG (2008) Best Dissertation in Biological Sciences (honorable mention), The University of Chicago (2008) Dr. Conrad's laboratory continues to be at the forefront of developing methodologies for analyzing genetic variation and its impact on reproductive health, with significant contributions to our understanding of the genomic basis for male infertility.

Karla Rodgersمشاهده پروفایل

استاد

• Immunology
• Molecular Biology
• Genetics
• +۳ مورد دیگر

Dr. Karla Rodgers is a Professor in the Department of Microbiology and Immunology at the University of Oklahoma Health Sciences Center. Her research focuses on understanding mechanisms regulating V(D)J recombination and its role in adaptive immunity. She holds a PhD from the University of Illinois, Urbana-Champaign, and has prior research experience at Yale University. Her research interests include: Molecular basis of antigen receptor gene diversification RAG1/RAG2 protein complex regulation DNA repair mechanisms during lymphocyte development Genetic defects causing immunodeficiency Her lab uses advanced techniques such as high-throughput recombination assays to study recombination signal sequence (RSS) specificity and investigates nuclear dynamics of RAG proteins under DNA damage conditions. Current lab personnel include graduate students Justin Harris and Cooper McKinney, and research technician John Ngo. Notable research directions include: Quantitative analysis of RSS sequence determinants DDR pathway interactions with V(D)J recombination Risk assessment of off-target RAG activity in leukemogenesis Dr. Rodgers has maintained an NIH-funded research program for over 15 years, with publications in leading journals such as Nucleic Acids Research and Immunobiology . Her work bridges basic immunology with clinical implications for immunodeficiency and cancer.

Chad A. Shawمشاهده پروفایل

استاد

• Statistics
• Genomics
• Systems Biology
• +۳ مورد دیگر

Chad A. Shaw is a Professor at Baylor College of Medicine and a Joint Professor of Statistics at Rice University. He serves as Director of the D2K Laboratory at Rice, and holds additional roles including Investigator at the Jan and Dan Duncan Neurological Research Institute and Faculty Member at the Baylor College of Medicine’s STaR Center and Quantitative & Computational Biosciences program. His expertise spans statistical genomics, bioinformatics, and molecular genetics. Education: BS in Mathematics (Duke University, 1995); PhD in Statistics (Rice University, 2001). Research Interests: Focuses on statistical methods for genomics, including next-generation sequencing analysis, structural variation studies, and clinical exome sequencing. Key contributions include probabilistic models for mutation transmission in human genetic diseases, copy-number variation analysis, and functionalization of genetic variants. His work bridges computational statistics with clinical applications, addressing challenges in rare disease diagnostics and Mendelian disorder modifiers. Publications: Over 200 peer-reviewed articles, including foundational studies on recurrence risk in genetic disorders and mechanisms of structural variation. Recent work emphasizes Bayesian modeling in sequencing assays, CNV-driven genetic diseases, and prenatal genomic analysis. Awards/Grants: No explicit awards mentioned, but his research has been cited ~17,000 times. Active in grant-funded projects across computational and clinical genomics. Advising: Trained 5 PhD students and advised over 10 others, with students contributing to areas like high-dimensional regression and software tools for variant prioritization. Labs/Teams: Leads the D2K Laboratory at Rice, fostering interdisciplinary research in data science and computational biology.

• Neurogenetics
• Inherited Peripheral Neuropathies
• Genetic Linkage Analysis
• +۴ مورد دیگر

Professor Marina Kennerson is a leading academic at the University of Sydney , affiliated with the Faculty of Medicine and Health and the School of Medical Sciences . She serves as Director of the Northcott Neuroscience Laboratory (ANZAC Research Institute), Principal Hospital Scientist at Concord Hospital's Molecular Medicine Laboratory, and Deputy Director (Research) for the Sydney Local Health District Institute of Precision Medicine and Bioinformatics. Her work focuses on Neurogenetics , particularly identifying causative genes for Inherited Peripheral Neuropathies (IPN), with over 25 years of experience in the field. Research Interests Gene discovery for IPN using genetic linkage and next-generation sequencing Functional genomics via iPSC-derived motor neurons and C. elegans models Transition of genomic technologies to clinical neurogenetic testing Leadership in global consortia like the Peripheral Nerve Society and Asian Oceanic Inherited Neuropathy Consortium Scientific Contributions Her research program integrates multiomics approaches with AI tools to analyze genomic data. She has identified 10 causative IPN genes and two structural variation mutations (DHMN1 and CMTX3), advancing pre-clinical modeling and therapeutic development. Her lab's work has established Concord Hospital as a reference center for IPN testing in Australia. Collaborations International partnerships include collaborations with: University of Malaya (Malaysia) – Dr. Azlina Ahmad-Annuar and Dr. Nortina Shahrizaila University of Miami (USA) – Professor Stephan Zuchner

Elisa De Francoمشاهده پروفایل

پژوهشگر ارشد

• Genetics
• Neonatal Diabetes
• Pancreatic Development
• +۵ مورد دیگر

Dr. Elisa De Franco is a Clinical and Biomedical Sciences researcher at the University of Exeter Medical School , affiliated with the NIHR Exeter Biomedical Research Centre. She has held prestigious fellowships including the Diabetes UK RD Lawrence Fellowship (2019-2024) and the EFSD/Novo Nordisk Future Leaders Fellowship (2023-2028). Elisa leads the neonatal diabetes genetic testing service at Diabetes Genes . Education: BSc (University of Turin, Italy, 2008) MSc (University of Turin, Italy, 2010) PhD (Peninsula College of Medicine & Dentistry, 2014) Research Focus: Elisa investigates genetic causes of neonatal diabetes, pancreatic development, and beta cell dysfunction. Her work integrates exome sequencing, whole genome sequencing, and bioinformatics to uncover novel disease mechanisms, with applications in type 1 diabetes research and cell-based therapies . Scientific Contributions: Her research has identified genes like PAX4, ZNF808, and FICD in neonatal diabetes etiology. She has published extensively in journals like Journal of Clinical Investigation and Diabetologia , with a focus on genotype-phenotype correlations , endoplasmic reticulum stress , and imprinting disorders . Awards: Diabetes UK RD Lawrence Fellowship (2019) EFSD/Novo Nordisk Future Leaders Fellowship (2023) Marie Curie BOLD Project Funding (PhD) Professional Activities: Elisa works part-time as a Healthcare Scientist in the NHS Exeter exome service (2017-2019) and leads international collaborations, including studies on genetic etiologies in Sudan, Vietnam, and Kurdistan. She is a key contributor to consensus reports on precision diabetes medicine.

Kevin C. Bylundمشاهده پروفایل

دانشیار

• Radiation Oncology
• Brachytherapy
• Cancer Treatment
• +۵ مورد دیگر

Kevin C. Bylund, M.D. is an Associate Professor in the Department of Radiation Oncology at the University of Rochester School of Medicine and Dentistry. He practices at Wilmot Cancer Center and Highland Hospital, specializing in radiation oncology with clinical focus on genitourinary and gynecologic cancers. Affiliated with the University of Rochester Medical Faculty Group and Accountable Health Partners, he actively treats patients with prostate, bladder, kidney, testicular, endometrial, and cervical cancers. Dr. Bylund's research centers on brachytherapy (both low-dose and high-dose rates), radiation therapy techniques, and protection of normal tissues during cancer treatment. His clinical interests include prostate cancer radiotherapy, gynecologic malignancies, and minimizing radiation side effects. His work demonstrates strong emphasis on adaptive radiotherapy , image-guided treatment planning , and managing radiation-induced complications . His recent publications (2020-2025) reveal dominant trends in Advanced brachytherapy techniques for prostate and gynecologic cancers Analysis of radiation toxicity and protective pharmacological interventions Innovations in cone beam CT-guided adaptive radiotherapy Metastatic patterns in prostate cancer with significant contributions to clinical trial methodology and radiation safety protocols. Scientific recognition includes: Educator of the Year (2015) RSNA Roentgen Resident/Fellow Research Award (2012) RSNA Roentgen Resident/Fellow Research Award (2008) As lead researcher for the PREDICT-RT* clinical trial (Parallel Phase III Randomized Trials for High Risk Prostate Cancer), Dr. Bylund directs significant grant-funded research investigating genomic risk-based treatment intensification/de-escalation. His educational contributions include systematic reviews on communication skills training for medical residents. Patient testimonials consistently highlight his compassionate communication style, technical expertise, and patient-centered approach to complex cancer treatment decisions.

Jessica Hardingمشاهده پروفایل

استادیار

• Diabetes Epidemiology
• Chronic Disease Research
• Kidney Disease and Transplantation
• +۳ مورد دیگر

Jessica Harding is an Assistant Professor in the Department of Epidemiology at Emory University. She holds a PhD in Medical Research (Epidemiology) from the Baker Heart and Diabetes Institute in Melbourne, Australia (2016), followed by a research fellowship at the Centers for Disease Control and Prevention (2017–2019). Her work focuses on chronic disease epidemiology, particularly diabetes and kidney disease, with an emphasis on population-level disparities and healthcare system challenges. At Emory, she contributes to the Transplant Health Services and Outcomes Research Program, addressing data quality and equity in kidney transplantation. Dr. Harding’s research interests include diabetes epidemiology, kidney disease progression, and the intersection of socioeconomic factors with health outcomes. Her studies often explore disparities in healthcare access, such as racial and gender inequities in kidney transplant eligibility and outcomes. Recent work has analyzed the impact of the COVID-19 pandemic on diabetes detection and management, highlighting shifts in telehealth utilization and pandemic-related disruptions to routine care. Her publications frequently address systemic barriers to transplant access, geographic variations in healthcare outcomes, and the role of gene-environment interactions in chronic diseases. She advocates for data harmonization and policy changes to improve equity in organ transplantation and chronic disease management.

Rachel Patzerمشاهده پروفایل

دانشیار

• Health Services Research
• Health Disparities
• Epidemiology
• +۷ مورد دیگر

Rachel Patzer is an Associate Professor in the Department of Epidemiology at Emory University’s Rollins School of Public Health. She holds a joint appointment as an Adjunct Professor in the Department of Surgery at Emory University School of Medicine. Dr. Patzer’s research focuses on health disparities, healthcare access, and quality of care, particularly in kidney transplantation and end-stage renal disease. She leads the Health Services Research (HSR) Center, a collaborative initiative between Emory’s departments of Medicine and Surgery, aiming to improve patient outcomes through evidence-based care delivery. Education: PhD, Emory University MPH, Emory University BS, University of Wisconsin-Madison Research Interests include: Disparities in social determinants of health Community-based participatory research Predictive analytics for transplant outcomes Mobile health technology (e.g., iChoose Kidney app) Medication adherence and self-management Healthcare resource utilization Recent Publications highlight work on racial/sex disparities in kidney transplant access, predictive modeling for transplant outcomes, and equity-focused interventions. Her studies appear in high-impact journals like JAMA , Am J Kidney Dis , and Health Affairs . Leadership Roles: Director, HSR Center Chair, UNOS Data Advisory Committee Member, Scientific Registry of Transplant Recipients Co-leader of E-STAR surveillance registry Advising & Teaching: Dr. Patzer mentors students and residents in the Departments of Surgery and Medicine, and teaches in Emory’s Master’s in Clinical Research (MSCR) Program.

Chrianna Bharatمشاهده پروفایل

پژوهشگر ارشد

• Epidemiology
• Data Linkage
• Opioid Dependence
• +۱ مورد دیگر

Chrianna Bharat is a Post-doctoral Research Fellow and applied biostatistician at UNSW Sydney's National Drug & Alcohol Research Centre. Awarded her PhD in 2023, her research utilizes person-level data linkage and analytical methods to study prescribed medicine use among opioid-dependent populations. Her epidemiological studies include population-linked investigations of substance use disorders and treatment outcomes. Research focuses on opioid dependence treatment, mortality risk factors, and predictive modeling using administrative health data. Publications demonstrate consistent focus on pharmacoepidemiology, with meta-analyses examining treatment effectiveness and mortality outcomes across global populations over the past five years.

Joan Morrisمشاهده پروفایل

استاد

• Epidemiology
• Congenital Anomalies
• Medication Safety
• +۱ مورد دیگر

Professor Joan Morris is Professor of Medical Statistics at St George's University of London's Population Health Research Institute. Her research focuses on the epidemiology of congenital anomalies and medication safety during pregnancy. She leads the EUROlinkCAT study, coordinating 22 European registries to analyze health outcomes of children with congenital anomalies through data linkage with hospital, mortality, prescription, and education records. Morris serves as scientific leader of EUROCAT (European network of congenital anomaly registries) and contributes to the ConcePTION project improving medication safety in pregnancy. Her work combines advanced statistical methodologies with clinical insights to inform public health policy, particularly regarding folic acid fortification and teratogen detection. Her recent publications demonstrate consistent focus on pediatric epidemiology, with particular attention to survival analysis, healthcare utilization patterns, and pandemic impacts on vulnerable populations. Research frequently utilizes multinational registry data to identify geographical variations in care and outcomes.