Konstantinos Anastassiadis is a Professor at the Center for Molecular and Cellular Bioengineering (CMCB) of Dresden University of Technology , leading the Stem Cell Engineering group at the Biotechnology Center (BIOTEC) . His research focuses on unraveling molecular pathways regulating stem cell self-renewal and lineage commitment, with a strong emphasis on genetic engineering tool development and epigenetic mechanisms during cellular reprogramming. The lab utilizes mouse and human embryonic stem cells, neural stem cells, mesenchymal stromal cells, and induced pluripotent stem cells (iPSCs) in their investigations. Core Research Areas: Molecular regulation of stem cell fate Epigenetic mechanisms (e.g., UTX/UTY histone demethylases) Genetic engineering tool development (Flp, Dre, Vika recombinases, CRISPR protocols) Conditional immortalization systems for rare cell expansion Publications highlight his contributions to understanding: Role of histone methyltransferases (MLL1, MLL2, Setd1b) in hematopoiesis and cancer Epigenetic regulation during mouse development and spermatogenesis Genetic tools for protein tagging, transposon-mediated BAC transgenesis Interactions between stem cells and niche microenvironments Transcriptional and mechanical markers during reprogramming Collaborations span immunology , developmental biology , and bioinformatics . The lab actively participates in teaching activities at CMCB and maintains a focus on translational applications of stem cell research.
Dieter Braun is a Professor in the Faculty of Physics at Ludwig Maximilian University of Munich (LMU), leading the Functional NanoSystems research group. He serves as speaker of the CRC 235 Emergence of Life and coordinates the Molecular Origins component of the Origins Cluster. Dr. Braun holds an ERC Synergy Grant (starting April 2025), leads the CRC 392 Molecular Evolution (starting April 2024), and is a Fellow in the Max Planck School Matter to Life (since October 2023). His research focuses on understanding the physical mechanisms that could have led to the emergence of Darwinian evolution from prebiotic molecules on early Earth. Braun's laboratory investigates non-equilibrium settings, particularly asymmetrically heated open cracks in rocks, which create intricate wet-dry cycles, temperature gradients, and fluidic effects that could drive molecular evolution. His work bridges physics, chemistry, and biology to explore how dead molecules might combine through physical forces into autonomous mechanisms of evolution. Analysis of Braun's recent publications reveals a strong focus on thermal gradients and non-equilibrium physics in prebiotic environments. His research demonstrates how heat flows can concentrate molecules, drive polymerization, create pH gradients, and enable non-enzymatic replication of nucleic acids. The publications span high-impact journals including Nature, Nature Physics, and Nature Chemistry, showing interdisciplinary work connecting physics, chemistry, geology, and biology in the context of life's origins. Klung-Wilhelmy Weberbank Price (2011) Technology Transfer Price of the DPG (with LMU and NanoTemper) Deutscher Innovationspreis (2012) Step Award (2012) Dr. Braun has successfully mentored numerous PhD students, including Stefan Duhr and Philipp Baaske who founded the award-winning startup NanoTemper Technologies. His research is supported by multiple prestigious grants including ERC Starting, Advanced, and Synergy Grants, as well as funding from the Simons Collaboration on the Origins of Life. His laboratory collaborates extensively with other researchers across disciplines and institutions, particularly with Hannes Mutschler in the new ERC Synergy project. The Braun laboratory operates within the CRC 235 Emergence of Life and the Origins Cluster at LMU Munich, with strong connections to the Max Planck Society through the Max Planck School Matter to Life. The research group maintains active collaborations with geochemists, biophysicists, and molecular biologists to create comprehensive experimental models of prebiotic environments.
Prof. Dr. Ralph Bock serves as Director of Department 3: Organelle Biology, Biotechnology and Molecular Ecophysiology at the Max Planck Institute of Molecular Plant Physiology in Potsdam, Germany, where he also leads the Organelle Biology and Biotechnology research group. Previously, he held positions as C4 Professor for Plant Biochemistry and Biotechnology at the University of Münster (2001-2004) and Group Leader at the Institute of Biology III, University of Freiburg (1996-2001). His academic credentials include: Habilitation: University of Freiburg, 1999 Doctorate: University of Freiburg, 1996 Diploma: University of Halle, 1993 Prof. Bock's research focuses on plant molecular biology with particular emphasis on chloroplast biology, organelle biotechnology, and molecular ecophysiology. His work spans genetic engineering of plastids, photosynthesis research, plant biotechnology applications, and understanding organelle-nucleus communication. He has made significant contributions to developing chloroplast transformation systems and applying them to molecular farming, metabolic engineering, and understanding fundamental processes in plant cell biology. His research has important implications for sustainable agriculture, bioenergy, and pharmaceutical production, particularly through the development of plant-based systems for producing vaccines and therapeutic proteins. Analysis of Prof. Bock's recent publications (2023-2025) reveals a strong focus on chloroplast biology, genetic engineering, and molecular farming applications. His work spans fundamental research on organelle genetics, photosynthesis, and stress responses, as well as applied research on using plant and algal systems for biopharmaceutical production. A notable trend is the increasing use of advanced genetic engineering techniques, including CRISPR-based approaches, to manipulate organelle genomes. His research also shows growing interest in algal systems as alternative expression platforms for molecular farming, particularly red algae like Porphyridium for producing viral antigens and glycoproteins.
Gheorghe Craciun is a Professor in the Department of Mathematics and the Department of Biomolecular Chemistry at the University of Wisconsin-Madison. His research focuses on mathematical and computational models in biology and medicine, particularly dynamical systems models of biological interaction networks. He has been a visiting researcher at the Max Planck Institute for Mathematics in the Sciences during the 2019-2020 academic year and has organized the Madison Workshops on Mathematics of Reaction Networks. Craciun's primary research interests include Mathematical Biology, Dynamical Systems, Chemical Reaction Networks, Computational Biology, Systems Biology, and Algebraic Geometry. He investigates systems of differential equations with polynomial right-hand sides, which are common in biochemical reaction networks, ecological interactions, and epidemiological models. His work often involves proving global stability, analyzing multistability, and characterizing steady states using tools from algebraic geometry and combinatorics. Recent publications demonstrate his focus on toric differential inclusions, endotactic networks, and the global attractor conjecture, extending to applications in biochemical networks and discrete Boltzmann equations. His extensive publication record reveals a strong trend toward algebraic and geometric methods for analyzing complex biological networks, with significant contributions to reaction network theory, stability analysis, and parameter characterization. Craciun's work bridges abstract mathematical concepts with practical applications in biochemistry, ecology, and medicine, including modeling vitellogenin production in trout and peptide mass distributions. He has collaborated extensively with international researchers including Alicia Dickenstein, Anne Shiu, Bernd Sturmfels, Casian Pantea, and Miruna-Stefana Sorea. In education, Craciun teaches graduate courses such as Math 703 and mentors students through the Madison Math Circle and Putnam Club, while organizing specialized workshops that foster collaboration in reaction network theory.
Prof. Dr. Job Boekhoven is an Associate Professor at the Department of Bioscience , TUM School of Natural Sciences , Technical University of Munich . His research focuses on synthetic life , chemically fueled self-assembly , and supramolecular materials , aiming to synthesize life from scratch. Research Interests include creating synthetic cells that compete for resources, replicate, and undergo Darwinian evolution . His lab designs molecules like lipids , peptides , and nucleic acids that self-assemble into active compartments regulated by chemical energy. These systems exhibit life-like hallmarks such as emergence , self-division , and controllable lifetimes . Scientific Awards include: ERC Consolidator Grant (2024) Lecturer Award by Association of the Chemical Industry (2024) ERC Starting Grant (2019) Volkswagen Foundation 'Life?' Grant (2019) Max Planck Fellow (2019) VCI Dozentenpreis (2021) Thieme Chemistry Journal Award (2017) Rubicon Postdoctoral Fellowship (2013) Publications highlight trends in nonequilibrium materials , dynamic combinatorial libraries , and protocell engineering . His work bridges synthetic chemistry with biophysics to explore life's origins and applications in materials science .
Prof. Dr. Jörg Stülke is a full Professor of Microbiology and Head of the Department of General Microbiology at the Institute of Microbiology and Genetics, University of Göttingen. He has held this position since 2003 and leads an active research group focused on bacterial metabolism and gene regulation. His research spans two major model systems: the pathogenic bacterium Mycoplasma pneumoniae and the well-studied Bacillus subtilis . His group employs systems-level approaches including transcriptomics, metabolomics, and bioinformatics to understand metabolic regulation and gene expression. Key interests include protein phosphorylation, RNA-mediated regulation, mRNA processing, and the role of second messengers such as cyclic di-AMP in bacterial physiology and pathogenicity. The recent publications reveal a strong trend in molecular microbiology, functional genomics, and systems biology. His work often integrates experimental and computational methods, particularly evident in the development and maintenance of the SubtiWiki database for B. subtilis . The research bridges fundamental mechanisms of life with applications in understanding bacterial virulence and cellular homeostasis. He is affiliated with several graduate programs under the Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), including: Molecular Biology (IMPRS) Biomolecules: Structure - Function - Dynamics (GZMB) Molecular Biology of Cells (GZMB) Microbiology and Biochemistry Genome Science (IMPRS) While no individual students are listed, he clearly supervises doctoral candidates through these programs. His group has secured significant research output, including publications in Science , Nucleic Acids Research , and PLOS Pathogens , indicating successful grant funding and collaborative research. The lab maintains a dedicated website at http://genmibio.uni-goettingen.de/ , which serves as a hub for research activities and resources like SubtiWiki.
Prof. Chris Meier is a distinguished Professor of Organic Chemistry at the University of Hamburg, Germany, where he leads the research group AG Meier within the Institute of Organic Chemistry, Department of Chemistry, Faculty of Mathematics, Informatics and Natural Sciences (MIN Faculty). With over two decades of academic leadership, he serves as Co-Speaker of Collaborative Research Center 1648 "Emerging Infections" and has held significant roles including Scientific Director of the Centre for Structural Systems Biology (CSSB) and President of the International Society for Nucleosides, Nucleotides and Nucleic Acids (IS3NA). Dr. Meier's educational background includes a Chemistry degree (Dipl. Chem.) from the University of Marburg/Lahn (1982-1987), followed by his doctorate in Organic Chemistry from the same institution (1987-1989). He completed postdoctoral research at the Pasteur Institute in Paris (1990-1991) and habilitated at Goethe University Frankfurt (1996) before his appointment as C4/W3 Professor at the University of Hamburg in 1999. Professor Meier's research program focuses on nucleoside and nucleotide chemistry, with particular emphasis on pronucleotide development, antisense oligonucleotide chemistry, and stereoselective synthesis of carbocyclic nucleoside analogs. His laboratory investigates molecular mechanisms of chemical carcinogenesis through synthesis of arylamine-modified oligonucleotides and develops innovative organic synthesis methods based on solid support. The group's work bridges fundamental organic chemistry with biomedical applications, particularly in antiviral and anticancer drug development. Recent publications highlight advancements in TriPPP ro -technology for nucleoside triphosphate delivery and metabolic labeling applications. 2018: Antonín Holý Memorial Award from the International Society for Antiviral Research (ISAR) 2007: William Prusoff Award from ISAR 1995: Adolf-Messer Prize for Interdisciplinary Research 1992-1996: Habilitation Scholarship from the German Research Foundation (DFG) 1990-1992: Liebig Postdoctoral Fellowship Professor Meier has successfully mentored numerous doctoral students and postdoctoral researchers, many of whom have gone on to establish independent research careers. His laboratory maintains active collaborations with virology and immunology groups across Europe, particularly with institutions in France (Pasteur Institute, University of Aix-Marseille) and Belgium (KU Leuven). The group has secured substantial funding through multiple Collaborative Research Centers (SFBs) and has developed several patented technologies related to pronucleotide delivery systems. The Meier laboratory operates state-of-the-art organic synthesis facilities within the Institute of Organic Chemistry and maintains close ties with the Centre for Structural Systems Biology (CSSB), where they utilize advanced imaging and structural biology techniques to characterize their compounds. The research group actively participates in the International Society for Antiviral Research and contributes to the development of novel antiviral strategies through both basic research and translational applications.
Prof. Dr. Felix Jonas is an Assistant Professor of Biochemistry at the School of Science, Constructor University Bremen, Germany. He leads research on the biochemistry of gene regulation , focusing on molecular mechanisms governing transcription factor function and chromatin dynamics in Saccharomyces cerevisiae . His work integrates CRISPR-Cas9, Next-Generation Sequencing, and computational data analysis. Education: B.Sc. in Molecular Life Sciences (University of Luebeck), M.Sc. in Biology: Cell Biology (ETH Zurich), Ph.D. in Bioengineering (Imperial College London) Work Experience: Postdoc/Senior Postdoc at Weizmann Institute of Science (2017-22), Visiting Student at Weizmann Institute (2015-16), International Program Associate at RIKEN (2011) Teaching: General Biochemistry (CH-100-B), Introduction to Bioinformatics (JTMS-10), Current Topics in Life Sciences (CA-BCCB-801), Advanced Biochemistry II - Molecular Genetics (CO-403-A) His research explores transcription factor target search , histone dynamics , and chromatin structure-function relationships . Recent publications highlight discoveries in nucleosome replacement, protein disorder grammar, and histone acetylation impacts on replication. Articles emphasize interdisciplinary approaches to eukaryotic gene regulation and systems biology. Visit his lab’s PhD recruitment page or watch his Fragile Nucleosome Talk for deeper insights into his work.
Jane A. McKeating is a Professor of Molecular Virology at the University of Oxford's Nuffield Department of Medicine. She holds the Hans Fischer Senior Fellowship at the Technical University of Munich's Institute for Advanced Study (TUM-IAS) since 2015. Her research focuses on viral infections, particularly hepatitis B (HBV) and C (HCV), exploring how hypoxia and circadian rhythms regulate viral replication and pathogenesis. She has held roles at institutions including the University of Birmingham (2005–2017) and Rockefeller University (2000–2005). Education: BSc in Biological Sciences, University of Warwick (1982) PhD in Virology, Royal Free Hospital School of Medicine, University College London (1987) Research Interests: Her work investigates how low oxygen (hypoxia) and circadian signaling pathways influence viral replication and tropism, particularly in liver and immune cells. Recent studies include SARS-CoV-2 regulation by hypoxia-inducible factors (HIFs) and circadian clock components like BMAL1. She also examines therapies targeting these pathways to combat viral infections. Publications: Her recent work spans hepatitis virus biology, antiviral screening tools, and circadian regulation of viral infections. Key themes include viral entry mechanisms, immune evasion, and drug development. Awards: 2015 Founders Award, University of Birmingham 2006 Royal Society Wolfson Merit Award 1995 Fleming Award, Society of General Microbiology Lab & Collaborations: Her research group at Oxford focuses on viral-host interactions, with collaborations on spatial transcriptomics of HBV/HDV/HIV co-infections and antiviral drug screening platforms.
Prof. Dr. Jörn Walter serves as a Senior Professor for Genetics and Epigenetics at Saarland University's Faculty of Natural Sciences and Technology. His laboratory investigates epigenetic mechanisms across development and disease states, with particular emphasis on DNA methylation, chromatin dynamics, and epigenomic mapping of cell types. Member of the International Human Epigenome Consortium (IHEC) Coordinator of the German Epigenome Program Director of an in-house Sequencing Facility (HiSeq2500, Mi-Seq, Nextseq-500) Research focuses include: Epigenetic programming during cellular differentiation DNA methylation dynamics in disease contexts Stem cell epigenetics and reprogramming Evolution of epigenetic mechanisms Recent publications highlight interdisciplinary approaches combining next-generation sequencing , bioinformatic modeling , and clinical epigenetics , with particular attention to immune cell development , metabolic disease epigenetics , and computational epigenomics . The group maintains collaborations with the West German Sequencing Center and contributes to epigenetic data standardization efforts. Lab members include active researchers like Dr. Nina Gasparoni , Dr. Gilles Gasparoni , and M.Sc. Alea Leismann , alongside an extensive alumni network of former advisees who have advanced epigenetic research in various institutions.
Dr. Stephanie Panier serves as a Max Planck Research Group Leader at the Max Planck Institute for Biology of Ageing in Cologne, Germany, and as a Principal Investigator at the Institute for Genome Stability in Aging and Disease within the Medical Faculty of the University of Cologne. Her research program investigates the fundamental mechanisms by which cells maintain genome stability through sophisticated DNA damage response pathways. Her academic journey includes: PhD in Molecular Genetics from the University of Toronto (2008-2013) under Prof. Daniel Durocher Postdoctoral training at the Francis Crick Institute in London (2013-2019) with Prof. Simon Boulton Undergraduate studies in Biology at Ruprecht-Karls-Universität Heidelberg, Germany (2001-2006) Dr. Panier's laboratory focuses on two central questions in genome stability research: how DNA damage response pathways interact with telomere maintenance mechanisms, and how RNAs and RNA-binding proteins organize chromatin-based responses to DNA lesions. Her team employs cutting-edge cell biological and omics approaches to identify and characterize RNA-binding proteins at DNA damage sites, mapping their chromatin dynamics and interactions following genotoxic stress. This research has significant implications for understanding aging-associated diseases driven by genomic instability, including cancer and neurodegeneration. Analysis of her publication record reveals consistent contributions to understanding DNA repair mechanisms, with recent work expanding into cancer biology, telomere maintenance in alternative lengthening pathways, and the emerging role of RNA metabolism in genome stability. Her scientific achievements have been recognized through: Vivash Award for best PhD thesis (2013) FEBS Excellence Award (2023) EMBO Long-Term Fellowship (2013-2014) Vanier Canada Graduate Scholarship (2010-2013) Boehringer Ingelheim Fonds PhD Fellowship (2008-2010) EIRR21st Fellowship (2023) Dr. Panier actively contributes to the scientific community through leadership roles including Vice Coordinator of the DFG Research Unit FOR5504 (2023-2026), membership on the advisory board of the German Society for Research on DNA Repair since 2022, and representation on the Biology and Medicine Section of the Max Planck Society's scientific council since 2022. She also serves as a Principal Investigator in the Cologne Excellence Cluster 'Cellular Stress Responses in Aging-Associated Diseases' (CECAD). Her laboratory comprises postdoctoral researchers and PhD students working collaboratively to advance our understanding of genome stability mechanisms in aging, with current projects focusing on RNA-binding proteins in DNA damage response and telomere maintenance pathways.
Dr. Wolfgang Zachariae is a Group Leader at the Max Planck Institute of Biochemistry in Martinsried, Germany, where he heads the "Chromosome Biology" research group. His laboratory focuses on understanding the molecular mechanisms of meiosis, particularly chromosome segregation and the role of cohesin in this process. Dr. Zachariae's educational background includes: PhD (summa cum laude) from Heinrich-Heine University, Düsseldorf, Germany (1990-1994), with Prof. Karin Breunig on "Regulation of the transcriptional activator Lac9" Diploma Thesis with Prof. Karin Breunig on "Enrichment of the transcription factor Lac9 from the yeast Kluyveromyces lactis" (1988-1990) Studies in Biology at Heinrich-Heine University, Düsseldorf, Germany (1984-1988) Postdoctoral Fellowship at the Institute of Molecular Pathology (IMP), Vienna, Austria (1994-1999), in the Laboratory of Prof. Kim Nasmyth, focusing on "cell cycle control by the anaphase-promoting complex in budding yeast" Dr. Zachariae's research focuses on the molecular biology of chromosome segregation during meiosis. His group uses baker's yeast as a model organism to study how chromosomes are correctly separated during the two meiotic divisions. A key focus is on cohesin, a molecular "glue" that holds chromosome pairs together, and how its regulated destruction ensures proper chromosome separation. His research employs diverse methodologies including genetics, biochemistry, video microscopy, and computational simulations of biochemical reactions. This work has significant medical relevance as errors in meiotic chromosome segregation are leading causes of infertility, miscarriage, and chromosome abnormalities like Down syndrome. Analysis of Dr. Zachariae's recent publications reveals a consistent focus on the molecular mechanisms of meiosis, particularly the regulation of cohesin and the anaphase-promoting complex (APC/C). His work spans from fundamental molecular mechanisms (such as phosphorylation of Rec8 by casein kinase) to the broader implications for gamete formation and chromosome segregation. The research demonstrates an interdisciplinary approach combining yeast genetics with advanced biochemical and imaging techniques. Dr. Zachariae has made significant contributions to the field of chromosome biology through his publications in top-tier journals including Cell, EMBO Journal, Developmental Cell, and Current Biology. His work on the regulation of meiotic chromosome segregation has provided fundamental insights into cell division processes that are conserved across eukaryotes. Dr. Zachariae leads an active research group consisting of PhD students (Nikoleta Milanovic, Addison E. Noronha, Vinal Massaad, Magdalena Matijevic), postdoctoral researchers (Olha Biriuk, Oleksii Lyzak, Marc Llavanera, Tugce Öz-Yoldas), and technical staff. His laboratory investigates the molecular mechanisms of chromosome segregation during meiosis using baker's yeast as a model system. The group has developed sophisticated approaches combining genetics, biochemistry, live-cell imaging, and computational modeling to understand how cohesin is regulated during the two meiotic divisions.
Günther Muth is a Research Professor at the University of Tübingen, where he leads a research group within the Interfaculty Institute of Microbiology and Infection Medicine. He is part of the Department of Microbial Bioactive Compounds under Heike Brötz-Oesterhelt's research team, focusing on the biology of Streptomyces plasmids and conjugative DNA transfer mechanisms. Dr. Muth completed his biology diploma at Friedrich-Alexander University in Erlangen and earned his doctoral degree in genetics under Alf Pühler at the University of Bielefeld. His postdoctoral training included positions at the department of genetics in Bielefeld, Behringwerke in Marburg, and returned to Bielefeld genetics department before working as a group leader in Wolfgang Wohlleben's groups from 1994-2019. His research focuses on the unique conjugation mechanisms in Streptomyces, which differ significantly from the type IV secretion systems found in other bacteria. He investigates how plasmids transfer DNA between bacterial cells and spread throughout recipient mycelium, with particular emphasis on the TraB protein as a DNA translocase. His laboratory has developed important genetic tools including the pSG5-based thermosensitive vector family for actinomycetes research. Analysis of Dr. Muth's recent publications (2015-2022) reveals a sustained focus on Streptomyces conjugation mechanisms, with increasing use of advanced imaging techniques like fluorescence microscopy. His work has progressed from basic conjugation studies to understanding molecular details of the TraB translocase and developing genetic tools, while recently expanding into metagenomic approaches for identifying biosynthetic gene clusters and plant-microbe interactions. Within his department, Dr. Muth leads Team Muth and collaborates with other research groups including Team Brötz-Oesterhelt, Team Hughes, Team Oesterhelt, Team Sass, and Team Stegmann. His laboratory currently includes PhD student Paul, Linkon, and likely receives research funding for his work on bacterial conjugation and plasmid biology, though specific grant details are not provided in the available information.
Prof. Hannes Mutschler is a faculty member at the Faculty of Chemistry and Chemical Biology of Technische Universität Dortmund , leading research in Chemical Biology with a focus on synthetic biology and origin-of-life studies. University: Technische Universität Dortmund School: Faculty of Chemistry and Chemical Biology Department: Chemical Biology Academic Rank: Professor Research interests include: De novo engineering of self-replicating and evolving biomimetic systems Origin of Life studies Ribozyme activity under prebiotically plausible conditions Bottom-up approaches using reconstituted protein/nucleic acid components Design of complex protein machineries and ribozymes Publication trends : Recent work explores ribozyme engineering for DNA/RNA catalysis Investigates RNA replication in prebiotic environments Develops synthetic RNA segregation systems Examines temperature-driven RNA proliferation in vesicles Focus on active droplets and coacervates as protocell models Contact: hannes.mutschler@tu-dortmund.de
Professor Zuzana Storchová is a leading researcher in molecular genetics at Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau (RPTU), Germany, where she has served as Professor of Molecular Genetics in the Department of Biology since 2016. Her research group focuses on understanding how changes in chromosome numbers and structure affect cellular functions, with critical implications for developmental defects and cancer pathologies. Her research program encompasses several key areas of investigation: Chromosomal aberrations and their cellular consequences Impact of chromosome gain on DNA replication and genomic stability Consequences of chromosome loss (monosomy) in human cells Maintenance of protein homeostasis in response to chromosomal imbalance Whole genome doubling and its contribution to genome evolution and cancer development Professor Storchová's laboratory employs cutting-edge technologies including biochemistry, cell biology, and multi-omics approaches to study the molecular processes affected by aneuploidy. They have developed specialized human cell lines with specific chromosomal abnormalities to investigate how cells respond to altered chromosome numbers. Using genomics, transcriptomics and proteomics, her team analyzes genome stability and protein homeostasis in aneuploid cells and elucidates the molecular links to human disease. Her publication record demonstrates a consistent focus on understanding the proteomic consequences of aneuploidy, mechanisms of genomic instability following whole-genome duplication, and therapeutic vulnerabilities of aneuploid cancer cells. Recent work has revealed how missegregation of even a single chromosome strongly affects cellular physiology, with many aneuploid cells failing to proliferate while others develop severe consequences including impaired protein homeostasis and compromised genomic stability. Professor Storchová's research trajectory shows a progression from fundamental chromosome biology to translational cancer research, with her work providing critical insights into how chromosomal abnormalities drive cancer development and identifying potential therapeutic targets for aneuploidy-associated diseases.
