جست‌وجوی استاد و پژوهشگر

Vivien Measdayمشاهده پروفایل

دانشیار

• Molecular Biology
• Genetics
• Genomics
• +۷ مورد دیگر

Vivien Measday is an Associate Professor at the Wine Research Centre , Faculty of Land and Food Systems , University of British Columbia. She holds associate memberships in the Department of Biochemistry and Molecular Biology and the Michael Smith Laboratories . Dr. Measday earned her BSc in Biochemistry from UBC (1991), PhD in Medical Genetics and Microbiology from the University of Toronto (1998), and conducted postdoctoral research in Medical Genetics at UBC (2003). Her lab investigates two primary programs: (1) the mechanism of Ty1 retrotransposon integration in Saccharomyces cerevisiae and (2) characterization of wine yeast populations in British Columbia's Okanagan Valley. Education: BSc (UBC), PhD (Toronto), Postdoc (UBC) Research Programs: Ty1 retrotransposon integration, Wine yeast terroir analysis Collaborations: Dr. Hung-Ta Chen (Academic Sinica), Dr. Simone Castellarin (UBC Wine Research Centre) Her research has produced 15+ publications since 2007, focusing on yeast genome maintenance, retroviral integrase interactions, and wine microbiome dynamics. Key findings include the role of RNA Polymerase III subunits in Ty1 targeting and the impact of commercial yeast strains on Okanagan vineyard populations. Scientific Recognition Canada Research Chair MSFH Education Award Dr. Measday supervises graduate students in the Food Science , Biochemistry and Molecular Biology , and Genome Sciences and Technology programs. Her team has identified novel yeast strains contributing to Okanagan wine terroir and elucidated conserved mechanisms of retroviral DNA integration.

Robin Anderssonمشاهده پروفایل

دانشیار

• Transcriptional regulation
• Enhancers
• Promoters
• +۴ مورد دیگر

Robin Andersson is an Associate Professor at the Department of Biology, University of Copenhagen , leading the Andersson Lab focused on modeling gene regulation to understand how enhancer and promoter dysregulation contribute to disease risk. His interdisciplinary research combines machine learning , statistical learning , genetics , and molecular biology to determine which noncoding sequences act as enhancers, predict regulatory activity from DNA sequences, and characterize mechanisms controlling gene expression variation. His research has produced significant insights into enhancer-promoter interactions , epigenetic inheritance , and transcriptional robustness . He has developed computational tools like ChromTransfer and hyperTRIBER for analyzing chromatin accessibility and RNA editing . His work bridges genomic mechanisms of disease with practical applications in noncoding variant interpretation and therapeutic target identification . Robin Andersson has received prestigious awards including the ERC Horizon 2020 Starting Grant , Sapere Aude Research Leader award , and Hallas-Møller Ascending Investigator award . He has supervised 17 MSc and 5 PhD students while contributing to academic service as PhD coordinator and strategic research board member. The lab maintains affiliations with the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease and FANTOM consortium , with recent grants focusing on single-cell regulatory mapping and disease variant interpretation .

• DNA Replication
• Chromosome Dynamics
• Genome Maintenance
• +۳ مورد دیگر

Professor Anne Donaldson is a Personal Chair at the University of Aberdeen within the School of Medicine, Medical Sciences and Nutrition, leading the 'Chromosome & Cellular Dynamics' Section at the Institute of Medical Sciences with six research groups focused on chromosome biology. Her educational background: BA in Natural Sciences, University of Cambridge (1989) PhD, MRC Laboratory of Molecular Biology, Cambridge (1994) Her research centers on DNA replication fidelity and chromosome maintenance mechanisms, using budding yeast to uncover evolutionarily conserved processes with direct cancer relevance. She investigates molecular controls over origin initiation, replication fork progression, and damage repair through advanced proteomic, genomic, and microscopy techniques, revealing fundamental insights into genome stability. Analysis of her 15 most recent publications shows dominant trends in replication timing regulation, RIF1-mediated fork protection, and phosphorylation-based control mechanisms. Her work increasingly integrates human cell models with yeast genetics, emphasizing clinical connections to cancer therapeutics through proteins like BRCA1 and RIF1 splice variants. Professor Donaldson actively mentors PhD students and postdoctoral researchers, with current opportunities advertised in her lab. Her research is supported by major grants: Cancer Research UK Programme Award (£1.56 million) investigating Rif1's role in replication recovery after chemotherapy Wellcome Trust Discovery Award (£2.48 million) examining Protein Phosphatase 1 in replication control She directs the Chromosome & Cellular Dynamics Section, fostering collaborative research across six groups that collectively advance understanding of chromosome replication, maintenance, and their implications for disease.

• Aging research
• Experimental pathology
• Medical biochemistry
• +۴ مورد دیگر

Takuya Chiba is a Professor at Waseda University's Faculty of Human Sciences, with significant contributions in aging research, calorie restriction biology, and DNA repair mechanisms. He holds a Ph.D. in Medicine from Kyoto University and has maintained affiliations with institutions like Nagasaki University and The Scripps Research Institute. Current: Waseda University, Faculty of Human Sciences (2014-present) Previous: Nagasaki University Graduate School of Biomedical Sciences (2002-2008) Research associate at The Scripps Research Institute (2001-2002) His research interests span multiple dimensions of aging biology, including: Neuroendocrine adaptation to caloric restriction Genomic instability and DNA repair in aging Metabolic reprogramming of adipose tissue CR mimetics development (taurine, rikkunshito) Mitochondrial supercomplex formation NPY and FoxO signaling pathways Scientific achievements include: Identifying Cox6b1's role in mitochondrial respiration enhancement Discovering SIRT1's deacetylation of PIP5Kγ in TSH regulation Elucidating NPY's essential role in CR-mediated lifespan extension Characterizing DNA repair pathways (POLQ, ERCC1/XPF) in aging Developing CR mimetic bioassays using DFCR-REs and HNF-4α His collaborative network includes key researchers like Isao Shimokawa, Toshimitsu Komatsu, and Ryoichi Mori. Current work focuses on: CR-induced multi-organ transcriptional networks Neuropeptide regulation of metabolic homeostasis Pharmacological targeting of aging-related pathways Comparative analysis of genetic vs dietary longevity interventions

Edwin Stanton Gelvinمشاهده پروفایل

استاد

• Plant Molecular Biology
• Agrobacterium-Mediated Transformation
• T-DNA Integration Mechanisms
• +۳ مورد دیگر

Dr. Stanton B. Gelvin is the Edwin Umbarger Distinguished Professor of Biology at Purdue University's Department of Biological Sciences. He leads research on Agrobacterium-mediated plant transformation, focusing on T-DNA integration mechanisms and improving crop transformation. His work bridges molecular biology, genetics, and agricultural biotechnology. Education: Ph.D., University of California, San Diego, 1977. Research Interests: Mechanisms of plant-microbe interactions, T-DNA trafficking and integration, and applications in genetic engineering. Key areas include understanding how Agrobacterium genetically modifies plants and developing technologies to enhance transformation efficiency in crops like corn and soybeans. Grants & Collaborations: NSF-funded projects on T-DNA integration and CRISPR applications. USDA grants for sweetpotato breeding using CRISPR-associated proteins. Industry partnerships with companies like Dow AgroSciences, CTC Genomics, and SweTree Technologies. Awards: Includes AAAS Fellowship, American Academy of Microbiology membership, and distinguished professorships. Key Contributions: Identification of plant genes (e.g., histones, myb transcription factors) influencing transformation, development of VirD2 mutant strains for integration-free T-DNA delivery, and advancing Ensifer-mediated transformation as an Agrobacterium alternative.

Andrew Ellingtonمشاهده پروفایل

استاد

• Synthetic Biology
• Directed Evolution
• DNA Computing
• +۲ مورد دیگر

Andrew Ellington is Professor in the Department of Molecular Biosciences at the University of Texas at Austin, holding the Wilson M. and Kathryn Fraser Research Professorship in Biochemistry. His pioneering research in synthetic biology develops novel organisms through translation apparatus engineering and computational nucleic acid design. Ellington directs the university's Gene Synthesis Facility. Research focuses on engineering genetic codes, developing DNA-based computational circuits, and creating modular cellular operating systems. Applications span diagnostics, therapeutics, and bio-computation, with recent work integrating machine learning for enzyme engineering and biomaterial design. Publications demonstrate foundational contributions to aptamer technology and synthetic biology, with recent advances in enzyme engineering for environmental applications and DNA circuit design. Research consistently bridges computational and experimental approaches. Ellington leads projects developing point-of-care diagnostics using isothermal amplification and DNA computation, and directs research on genetic code expansion for novel protein functions.

David H. Collingwoodمشاهده پروفایل

استاد

• Genomics
• DNA Replication Dynamics
• Representation Theory of Lie Groups and Lie Algebras
• +۳ مورد دیگر

Roles & Affiliations Professor of Mathematics at the University of Washington since at least 1983. Specializes in both pure mathematics (Representation Theory of Lie Groups) and interdisciplinary genomics research. Active in mathematics education reform, particularly calculus and precalculus curriculum development. Education PhD in Mathematics, University of Utah, 1983 Research Interests Current focus on genomic DNA replication dynamics using microarray technology, exemplified by landmark 2001 Science paper analyzing yeast genome replication timing. Prior work involved Whittaker models and Harish-Chandra modules. Balances pure math research with applied genomics projects. Teaching Contributions Recipient of 1998-99 UW Distinguished Teaching Award. Led UW's calculus curriculum reform emphasizing problem-solving and TA training. Authored widely-used precalculus textbook with problem-solving focus. Collaborated with community college educators through sabbatical fellowship programs. Key Collaborations Genomics work with M. K. Raghuraman and Ronald Davis High school curriculum collaboration with Marilyn Stor

John M. Mercerمشاهده پروفایل

استاد

• Evolutionary Biology
• Genetics
• Molecular Systematics
• +۳ مورد دیگر

John M. Mercer is a Professor of the Practice in Biology and Physics at Duke University’s Trinity College of Arts & Sciences. He holds a PhD from Yale University (1981) and has held academic roles since 1991, including Associate Director of Undergraduate Studies in Physics and various teaching appointments in Biology and Physics. His research spans evolutionary biology, genetics, biophysics, and molecular systematics, with notable work on squirrel phylogeny, genetic mechanisms in Drosophila, and molecular dynamics. Recent grants include NIH-funded studies on complement responses and NSF-supported molecular systematics research. Mercer teaches courses like Biophysics, Mathematical Modeling in Biology, and Advanced Experimental Physics. He has served as an ad hoc reviewer for peer-reviewed journals and contributed to editorial activities in multiple fields. Education: PhD in Biology, Yale University, 1981 Affiliations: Dual departmental roles in Biology and Physics at Trinity College Grants: NIH (2023–2025), NSF (1998–2002) His publications reflect interdisciplinary focus, with key contributions to evolutionary processes, genetic architecture, and biophysical modeling. Mercer actively engages in undergraduate education and outreach, emphasizing practical experimental training and interdisciplinary approaches.

Laura Buttittaمشاهده پروفایل

استاد

• Cell Cycle Regulation
• Developmental Biology
• Cancer Biology
• +۳ مورد دیگر

Laura Buttitta is a Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan. Her research focuses on understanding how cells exit the cell cycle to enter quiescence (G₀ phase), particularly in differentiated and stem cells, using Drosophila and mammalian models. She joined the department in 2011 after completing her PhD at Johns Hopkins University (2004) and postdoctoral work at the Fred Hutchinson Cancer Research Center under Dr. Bruce Edgar. Her lab investigates mechanisms controlling cell cycle arrest and reactivation during development and disease, with applications to cancer and tissue regeneration. Key areas include cell cycle regulation in quiescent states, chromatin remodeling during differentiation, and the role of miRNAs like miR-8 in cell survival and epithelial organization. Current research emphasizes the molecular pathways linking cell cycle exit to cellular functions, including how quiescent states vary in reversibility. Her work bridges developmental biology and oncology, with findings published in top-tier journals and supported by grants from NIH and other agencies. Contact: buttitta@umich.edu , Office: 5218 Biological Sciences Building

• Single-Molecule Biophysics
• Super-Resolution Microscopy
• Mitochondrial Metabolism
• +۴ مورد دیگر

Dr. Peter Su is a Senior Lecturer in the School of Biomedical Engineering at the University of Technology Sydney (UTS), affiliated with the Faculty of Engineering and IT. He holds an NHMRC Emerging Leadership Fellowship and serves as Theme Lead in the School. His research focuses on quantitative imaging at nanoscale, integrating super-resolution microscopy and biophysical tools to study molecular mechanisms in mitochondrial dynamics, thrombosis, and cardiovascular disease. He is also a Visiting Scientist at the Heart Research Institute (HRI) and the University of Sydney. Education: PhD in Single-Molecule Biophysics (Peking University, 2017), postdoctoral training at Harvard (2012), and leadership roles in NHMRC-funded projects. Research spans three pillars: Dynamic Imaging (motor-driven membrane dynamics), Molecular Imaging (chromatin structures), and Functional Imaging (platelet mechanosensors). Publications highlight innovations in super-resolution microscopy, mitochondrial thermal dynamics, and thrombotic disease profiling. His lab collaborates internationally with institutions like Tsinghua University and UC Berkeley, and locally with Sydney's Heart Research Institute and Centenary Institute. Grants include NHMRC Investigator Grants, ARC Discovery Projects, and industry partnerships. Supervision of 15 HDR students and leadership in imaging facilities (Volumetric Imaging, Single-Molecule Manipulation) showcase his translational research impact. Awards include Young Biophysicist of the Year (2019) and multiple early-career recognitions.

Sami El Hilaliمشاهده پروفایل

پژوهشگر

• Molecular Biology
• DNA Replication
• Genomics
• +۳ مورد دیگر

Sami El Hilali is a Researcher affiliated with the Guse Lab at Ludwig-Maximilians-Universität München . His work focuses on genomic stability , particularly mechanisms governing DNA replication stress, common fragile sites, and their implications in cancer and neurodevelopmental disorders. He contributes to cutting-edge research on genome assembly in extremophile organisms and develops bioinformatics tools for genomic visualization. Research interests include: DNA replication dynamics and checkpoint regulation Genome instability in fragile X syndrome Transcription-replication interactions Functional genomics of extreme environments Key contributions bridge molecular mechanisms (e.g., ATR/DDK signaling) with large-scale genomic analyses, employing innovative tools like macrosyntR for Oxford Grid visualization. Current projects explore how replication stress impacts chromosomal architecture and disease pathogenesis. His lab affiliations emphasize collaboration on multi-organism studies from model systems to hydrothermal vent species, revealing fundamental principles of genome organization under stress conditions.

• HIV/AIDS Research
• Cell Biology
• Virology
• +۶ مورد دیگر

Thomas J. Hope is a Professor of Cell and Molecular Biology (Feinberg School of Medicine) and Biomedical Engineering (McCormick School of Engineering) at Northwestern University. His research focuses on HIV cellular virology, mucosal immunology, and prevention science, using advanced imaging techniques to study viral entry, assembly, and transmission dynamics. He leads the Hope Lab, which pioneers microscopic imaging of HIV interactions with cells and tissues to inform HIV prevention strategies like vaccines and microbicides. His work integrates molecular biology, biochemistry, and genetics to address early HIV transmission steps and develops tools for in vivo tracking of viral particles. Education: PhD in Immunology from UC Berkeley (1988), postdoctoral fellowship at UCSF (1992). His lab’s recent work includes SARS-CoV-2 studies, exploring mucociliary clearance effects on viral spread and PET/CT imaging of HIV distribution. Collaborations span HIV cure research, including TGF-β blockade to reactivate latent reservoirs, and global PrEP strategy evaluations. Publications highlight interdisciplinary approaches, with a focus on viral dynamics, antibody distribution, and innovative imaging. The lab’s translational efforts aim to reduce HIV transmission through better understanding of mucosal barriers and immune responses.

Zongliang (Carl) Jiangمشاهده پروفایل

دانشیار

• Animal Sciences
• Reproductive Biology
• Stem Cell Research
• +۳ مورد دیگر

Dr. Zongliang (Carl) Jiang is an Associate Professor in the Department of Animal Sciences at the University of Florida, affiliated with the UF Genetics Institute and the Institute of Food and Agricultural Sciences (IFAS). He holds a PhD from the University of Connecticut (2015) and completed postdoctoral training at Yale School of Medicine and the University of Connecticut. His academic positions include roles as Doyle Chambers Distinguished Professor at Louisiana State University (2022) and previous faculty roles there from 2017-2022. Dr. Jiang’s research focuses on reproductive and developmental biology, particularly in stem cell biology, epigenetic regulation in embryos, and mitochondrial dynamics. His work spans bovine and human systems, addressing topics like embryo competence, stem cell culture, and genomic imprinting. Key projects include establishing bovine extraembryonic stem cells and investigating translational oscillations in oocytes. His scientific awards include the Doyle Chambers Distinguished Professorship. Research outputs emphasize high-impact areas such as stem cell engineering, transcriptomic profiling, and developmental genetics. He is actively involved in teaching and advising within the Animal Sciences department.

Georgii Bazykinمشاهده پروفایل

استاد مهمان

• Population Genetics
• Evolutionary Biology
• Computational Biology
• +۲ مورد دیگر

Georgii Bazykin is Visiting Professor in Emory University's Department of Biology. His research spans computational biology, evolutionary genetics, and pathogen evolution. Focus areas include natural selection patterns, mutational processes, and viral adaptation. Research: Develops methods to infer selection from genomic data, studies mutagenesis in cancer/germline cells, and predicts pathogen evolution. Notable work on SARS-CoV-2 evolution and mitochondrial genetics. Publications: Recent studies examine viral evolution during long COVID, recombination in tick-borne viruses, and mutational signatures in bacteria. Specializes in evolutionary analysis of pandemic viruses.

Arvind Muruganمشاهده پروفایل

دانشیار

• Quantitative Biology
• Non-Equilibrium Dynamics
• Theoretical Computer Science
• +۷ مورد دیگر

Arvind Murugan is an Associate Professor in the Department of Physics at the University of Chicago and a member of the Committee on Computational and Applied Mathematics (CCAM). His research focuses on quantitative biology, non-equilibrium dynamics, and theoretical computer science, particularly in understanding how physical and biological systems can learn and adapt through collective dynamics. Affiliations: Gordon Center for Integrative Science, U Chicago Center for Living Systems Research Interests: Physical learning mechanisms in non-equilibrium systems Molecular self-assembly and error correction Active matter and biological regulation Associative memory in molecular networks Interdisciplinary approaches combining physics, biology, and computer science Publication Trends: His recent work explores soft modes in biological systems, temporal contrastive learning in physical systems, and error correction mechanisms in molecular processes. These studies bridge physics, computational biology, and materials science, revealing how simple physical systems can exhibit complex learning behaviors. Scientific Awards & Funding: Supported by NSF, NIH, Simons, Sloan, Moore, and Chan Zuckerberg Foundations Lab members funded by James S. McDonnell, Hertz, and NSF fellowships Collaborations & Lab: The Murugan Lab collaborates with the Rust, Tay, Wang, Elowitz, Hwa, Pincus, and Szostak labs. They actively seek researchers with expertise in molecular biology and high-throughput evolution to advance physical learning systems.