Coronary Microvascular Dysfunction Professors and Supervisors

Mattia Galliمشاهده پروفایل

پژوهشگر

Sapienza University of RomeItaly

Mattia Galli is a Researcher at the Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome. He teaches courses including Cardiovascular Instrumental Diagnostics, Human Anatomy, and Clinical Nursing in Cardiovascular Disease. His academic work focuses on cardiovascular medicine and biotechnologies with a strong emphasis on clinical applications. Dr. Galli's research spans multiple areas of cardiovascular medicine with particular expertise in: Antiplatelet and anticoagulant therapies Percutaneous coronary interventions Cardiovascular pharmacology Thrombosis and bleeding risk management Personalized medicine approaches in cardiology Platelet function and genetic testing His recent publications (2023-2024) demonstrate a strong focus on optimizing antiplatelet therapy, particularly examining factors like genetic variations, renal function, and ethnic differences that affect treatment response. His work often involves meta-analyses and clinical trials, including several SWAP studies examining therapy switching protocols and the TAPER-S study on ischemic preconditioning. He has made significant contributions to understanding high bleeding risk scenarios, aspirin hypersensitivity, and dual pathway inhibition strategies. Dr. Galli's research bridges the gap between pharmacological mechanisms and clinical practice, aiming to improve patient outcomes through evidence-based approaches. His work has appeared in top-tier journals including European Heart Journal, JACC, and Nature Reviews Cardiology, reflecting the high impact of his contributions to the field of cardiovascular medicine.

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Süha Çetinمشاهده پروفایل

دانشیار

Okan UniversityTurkey

Prof. Dr. Süha Çetin is an Associate Professor and interventional cardiologist at Okan University Hospital in Istanbul, where he has served in the Department of Cardiology since 2016. Fluent in German and English, he specializes in advanced cardiac imaging and interventional procedures, with clinical expertise developed through training at Ulm University and institutions in North America and the UK. Education Medical Education: University of Tübingen, Germany Cardiology Specialist Training: University of Ulm, Germany Cardiology Education: Ohio, North America Interventional Cardiology Training: Bristol Heart Institute and Leicester Royal Infirmary, UK Research Interests His research centers on cardiovascular pathophysiology in sleep disorders, particularly obstructive sleep apnea's impact on cardiac structure and function. He employs advanced echocardiographic techniques including speckle tracking to investigate left atrial/ventricular remodeling, coronary microvascular dysfunction in diabetes, and cardiotoxicity in cancer survivors. His work bridges clinical cardiology with metabolic and autoimmune conditions. Publication Trends Analysis of his 15 most recent publications (2014-2024) reveals persistent focus on sleep apnea-cardiac interactions (37% of works), with secondary themes in diabetic coronary disease (13%), cardio-oncology (7%), and stroke-related cardiac mechanisms (13%). Over 60% utilize echocardiography innovations, demonstrating his methodological specialization in strain imaging and functional assessment. Recurring co-authors indicate established collaborations with Vural MG and Heper G across multiple studies.

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Jacob Thomsen Lønborgمشاهده پروفایل

دانشیار بالینی

University of CopenhagenDenmark

Jacob Thomsen Lønborg serves as a Clinical Associate Professor at the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen. His clinical and research work is closely affiliated with Region Hovedstaden (Capital Region of Denmark) where he practices at the address Blegdamsvej 3, 2200 København N. His academic career focuses on interventional cardiology with particular expertise in acute coronary syndromes and complex revascularization strategies. Dr. Lønborg's research interests center on interventional cardiology , specifically examining optimal treatment approaches for ST-elevation myocardial infarction (STEMI) patients with multivessel disease. His work investigates long-term outcomes of different revascularization strategies, the impact of novel pharmacotherapies on cardiovascular outcomes, and advanced imaging techniques to assess vascular inflammation. He has made significant contributions to understanding cardiogenic shock management and microvascular dysfunction following myocardial infarction. His publication record demonstrates a strong focus on large-scale clinical trials, particularly the DANAMI-3 program (PRIMULTI and DEFER studies) and the DanGer Shock substudy. These works have received substantial attention in the medical community, with several papers being referenced in clinical guidelines and picked up by numerous news outlets. His research has been published in top-tier journals including the New England Journal of Medicine , Journal of the American College of Cardiology , and Circulation . Dr. Lønborg actively collaborates with leading cardiovascular researchers across Denmark and internationally, contributing to multi-center clinical trials that shape contemporary cardiology practice. His work bridges clinical practice with academic research, translating findings into improved patient care for those suffering from acute coronary syndromes and related complications.

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Jens P. Gotzeمشاهده پروفایل

استاد بالینی

University of CopenhagenDenmark

Jens P. Gotze is a Clinical Professor at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. He serves as Chief Physician at the Department of Clinical Biochemistry, Rigshospitalet, Denmark, with responsibilities including education and training of junior doctors since 2015. His academic journey includes positions at Copenhagen University, Aarhus University, and collaborations with international institutions including the Mayo Clinic. Gotze's research focuses on cardiovascular endocrinology, particularly natriuretic peptides and their role in heart disease, thrombosis, and hemostasis. His work bridges biochemical methodology, experimental models of human heart disease, and clinical studies, requiring close collaboration between basic scientists and clinicians. His research vision aims to consolidate cardiovascular endocrinology as a cross-functional discipline using innovative biochemical and molecular methods. His extensive publication record includes 206 research outputs with significant citations and an H-index of 29. His recent work explores topics including natriuretic peptides in gastrointestinal function, molecular characterization of cardiac tissue, and biomarkers for cardiovascular diseases. Winner of lecture competition for young cardiologists in Scandinavia (2003) 2nd place at the Astrup competition (2004) Christenson-Ceson scholarship (2006) 'Jakobinermedaljen' by Selskabet for Teoretisk og Anvendt Medicin (2008) Research Award of the Odd Fellow Order (2014) Gotze actively supervises numerous PhD students, postdocs, and other trainees, and has served as an assessor for PhD theses internationally. He has secured substantial research funding from foundations including Lundbeck Foundation, Novo Nordisk Foundation, and The Capital Region of Denmark. His leadership extends to managing the coagulation section at Rigshospitalet and the peptide research section, demonstrating significant administrative responsibilities alongside his research and teaching duties.

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Muhammet Salih ATEŞمشاهده پروفایل

استادیار

Ahi Evran UniversityTurkey

Dr. Muhammet Salih ATEŞ is a full-time Assistant Professor at the Department of Internal Medical Sciences, Faculty of Medicine, Kırşehir Ahi Evran University, Turkey, where he has been employed since 2023. His academic qualifications include a Medical Specialization from Selçuk University's Faculty of Medicine (2016-2020) and a Bachelor's Degree in Medicine from Atatürk University (2009-2015). His research focuses on cardiovascular pathophysiology with specialized interests in hypertension diagnostics, electrocardiographic biomarkers, inflammatory indices in cardiac conditions, myocardial infarction mechanisms, and metabolic interactions in cardiovascular disease. He maintains active collaborations with researchers from Selçuk University and Necmettin Erbakan University. ATES's recent publications (2023-2025) demonstrate three primary research trends: 1) Novel ECG parameters (P-wave indices, T-P angle) for predicting coronary complexity; 2) Inflammatory biomarkers (pan-immune-inflammation index, neutrophil volume) in hypertension and diabetes; and 3) Platelet indices in acute coronary syndromes. His work frequently appears in SCI-indexed journals including the Journal of Electrocardiology and Journal of Clinical Medicine . He has collaborated extensively with 33 researchers, most frequently with Abdullah Tunçez (12 collaborations), Bülent Behlül Altunkeser (10 collaborations), and Erdoğan Sökmen (9 collaborations). Metrics show a Scopus h-index of 2 with 31 citations across 34 publications.

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Elize de Jongمشاهده پروفایل

پژوهشگر

Utrecht UniversityNetherlands

Elize de Jong is a Researcher at the University Medical Center Utrecht , focusing on cardiovascular diagnostics and pathophysiology. She specializes in coronary endothelial dysfunction , microvascular resistance , and invasive coronary function testing for patients with angina and non-obstructed coronary arteries . Her work includes collaborations with experts like Jan J. Piek and Tim P. van de Hoef. Recent publications highlight her contributions to hyperaemic microvascular resistance , acetylcholine infusion protocols , and blood flow dynamics in coronary artery disease. Studies explore the impact of coronary hyperemia on collateral flow, myocardial blood volume mechanisms, and diagnostic accuracy in nonobstructive cases.

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Rigobert Lapu-Bulaمشاهده پروفایل

دانشیار

Morehouse School of MedicineUnited States

Rigobert Lapu-Bula, M.D., Ph.D. serves as Associate Professor of Medicine at Morehouse School of Medicine, where he directs the MDI Curriculum in Cardiovascular Physiology and Cardiovascular Hemodynamic and Ultrasound Core. His academic career bridges clinical cardiology, cardiovascular research, and health disparities elimination through the Community Physicians' Network. Medical Degree: University of Kinshasa Ph.D.: Catholic University of Louvain (Exercise Physiology and Heart Failure) Dr. Lapu-Bula's research program focuses on cardiovascular phenotyping with special emphasis on blood pressure regulation, salt-sensitivity, and microgravity adaptation (NASA Space Medicine). His work uniquely examines ethnic disparities in cardiovascular disease presentation and outcomes, particularly among African American populations. Key contributions include elucidating nitric oxide-mediated pathways in hypertension progression to heart failure and identifying risk factors for myocardial infarction in patients with normal coronary arteries. His publication record demonstrates consistent output in high-impact journals including JAMA , Circulation , and American Journal of Cardiology , with recent work addressing vascular disease determinants in African American women. Research trends show evolution from basic mechanisms of endothelial dysfunction toward community-based interventions for healthcare disparities. 2011: Certificate of Appreciation for Mentoring in Vivien Thomas Summer Research Program 2009: Honorary Class Member Award for Morehouse School Medicine Master of Science in Clinical Research As Director of the MDI Cardiovascular Curriculum, Dr. Lapu-Bula trains medical students in cardiovascular physiology and ultrasound techniques. His leadership in the Community Physicians' Network demonstrates commitment to translating research into practice through academic-community partnerships that improve hypertension management in underserved populations. The Cardiovascular Research Institute provides infrastructure for his work examining genetic, physiological, and social determinants of cardiovascular health disparities.

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Frédéric Lesageمشاهده پروفایل

استاد

Polytechnic School of MontrealCanada

Frédéric Lesage is a Full Professor in the Department of Electrical Engineering at Polytechnique Montréal and holds a Tier 1 Canada Research Chair in Vascular Optical Imaging. His multidisciplinary research bridges biomedical engineering, neuroscience, and AI, with affiliations spanning the Functional Imaging Laboratory (INSERM), Montreal Heart Institute, and Centre for Mathematical Research. Research interests center on neuroimaging innovations for studying cerebral physiology. Key areas include: Neurovascular Coupling: Investigating blood flow dynamics in aging and Alzheimer's using optical coherence tomography and NIRS. Epilepsy Diagnostics: Developing AI models for seizure prediction via EEG/fNIRS fusion. Microvascular Pathologies: Mapping microstroke impacts using two-photon microscopy and adversarial learning. His 15 most recent publications (2020-2025) emphasize AI-driven neurology applications, showing trends in: Machine learning for epileptic EEG analysis Cerebral pulsatility in neurodegenerative diseases Translational vascular imaging (OCT/TPM) Awards include the Canada Research Chair (Tier 1) , renewed in 2022 for pioneering vascular imaging techniques. He has advised 57+ graduate students (27 PhD, 30 Master's) and secured grants from NSERC, CIHR, and CRC. Current projects focus on hypoxia effects, statin therapy in Alzheimer's, and catheter-based surgical simulators.

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David X. Zhangمشاهده پروفایل

دانشیار

Medical College of WisconsinUnited States

Dr. David X. Zhang is an Associate Professor in the Department of Medicine, Division of Cardiology at the Medical College of Wisconsin, where he is also a member of the Cardiovascular Research Center. His academic career bridges clinical medicine (MD) and basic science research (PhD), positioning him at the forefront of translational cardiovascular research. Dr. Zhang's research focuses on the molecular mechanisms of vascular function, with particular emphasis on endothelial physiology, ion channel regulation (especially TRP channels), and the signaling pathways that control vasodilation and vascular tone. His laboratory investigates how reactive oxygen species (NO, H2O2), calcium signaling, and various mediators regulate human microvascular function in both health and disease states. Key areas of investigation include the role of TRPV4 channels in vascular signaling, mechanisms of endothelial dysfunction in coronary artery disease, and the vascular consequences of inflammatory conditions including SARS-CoV-2 infection. Analysis of Dr. Zhang's recent publication record (2019-2025) reveals a consistent research trajectory focused on molecular vascular mechanisms with direct clinical relevance. His work frequently employs human tissue models, providing translational significance to his findings. The publications demonstrate expertise in multiple methodologies including human microvessel physiology, molecular signaling analysis, and structural biology approaches. His research has made significant contributions to understanding alternative vasodilator mechanisms, ion channel regulation in vascular tissue, and the molecular basis of endothelial dysfunction. Dr. Zhang maintains an active collaborative network, as evidenced by his numerous multi-institutional publications. His work has been published in high-impact journals including Nature Communications, Journal of Biological Chemistry, Arteriosclerosis Thrombosis and Vascular Biology, and Basic Research in Cardiology. While specific grant details aren't provided, the sustained productivity and sophisticated nature of the research suggest substantial ongoing funding support. For students and researchers interested in vascular biology, Dr. Zhang's laboratory offers opportunities to work at the intersection of basic science and clinical cardiovascular research, with emphasis on human vascular physiology and molecular signaling mechanisms that have direct relevance to cardiovascular disease pathogenesis and potential therapeutic targets.

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Andreas M. Beyerمشاهده پروفایل

استاد

Medical College of WisconsinUnited States

Andreas M. Beyer, PhD, is Professor of Medicine and Physiology at the Medical College of Wisconsin where he co-directs the Basic and Translational Research Program in Cardio-Oncology. He holds appointments in the Cardiovascular Research Center and Cancer Center. His research program investigates microvascular pathophysiology with focus areas in mitochondrial biology, redox regulation, and cardiovascular complications of cancer therapies. Dr. Beyer's research integrates human microvascular studies with mechanistic animal models to examine: mitochondrial homeostasis in vascular tone regulation, telomerase functions beyond telomere maintenance, endothelial dysfunction mechanisms in coronary artery disease, and cardiovascular toxicities of anti-cancer treatments. His lab pioneered techniques for assessing human microvascular function and genetic manipulation of human vessels. Research publications demonstrate consistent focus on vascular signaling pathways, particularly: redox-mediated vasodilation transitions in aging/disease, mitochondrial dynamics in endothelial function, telomerase-mediated vascular protection, and cardio-oncology interactions. Recent work explores vascular implications of COVID-19 and environmental factors in cardiovascular outcomes. Awards and honors include: Outstanding Young Investigator Award, Microcirculatory Society (2014) Fellow of the American Heart Association (FAHA, 2016-present) Merck New Investigator Award, AHA Council of High Blood Pressure (2006) International Travel Award for Young Investigators, APS-TPS (2016) Top 3 Reviewer, Journal of the American Heart Association (2016) Dr. Beyer actively mentors trainees at all levels, currently supervising 2 postdoctoral researchers, 3 graduate students, and a research scientist. His NIH-funded research program includes collaborations across cardiology, oncology, and physiology disciplines. The Beyer Lab utilizes human tissue models, genetic approaches, and physiological assessments to bridge mechanistic insights to clinical applications in vascular medicine.

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Gökay Taylanمشاهده پروفایل

دانشیار

Trakya UniversityTurkey

Gökay Taylan serves as an Associate Professor in the Department of Cardiology at Trakya University Faculty of Medicine since 2023, having previously held an Assistant Professor position from 2018. His academic journey includes a Doctoral Degree (MD) completed in 2015. Research Focus: Dr. Taylan specializes in complex cardiac conditions with emphasis on Takotsubo syndrome , arrhythmia mechanisms , and myocardial infarction complications . His work integrates advanced imaging techniques with biomarker analysis to address critical gaps in cardiac risk stratification. Current investigations focus on glucose-potassium ratios as mortality predictors in critical care settings and innovative approaches to atrial fibrillation ablation. His publication portfolio demonstrates significant contributions to understanding Brugada syndrome phenocopies , coronary microvascular dysfunction , and post-MI remodeling . Recent collaborative work includes the MORCOR-TURK trial analyzing coronary care unit mortality predictors. Dr. Taylan actively supervises doctoral research, with one completed dissertation examining fragmented QRS complexes in hemodialysis patients. His clinical work emphasizes translational applications in cardiac electrophysiology and preventive cardiology programs for atrial fibrillation management.

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