جست‌وجوی استاد و پژوهشگر

Maja Bucanمشاهده پروفایل

استاد

• Genetics
• Genomics
• Psychiatric Genetics
• +۳ مورد دیگر

Maja Bucan, PhD, is a Professor of Genetics and Co-Director of the Autism Spectrum Program of Excellence at the Perelman School of Medicine, University of Pennsylvania. Her research focuses on genetic dissection of complex behaviors in mice and humans, with expertise in functional genomics , bipolar disorder , and autism spectrum disorders . She is affiliated with multiple graduate groups, including Cell and Molecular Biology, Genomics and Computational Biology, and Neuroscience. Research Interests Dr. Bucan investigates: Genetic basis of psychiatric disorders (autism, bipolar disorder) Role of circadian rhythms in mental health Functional annotation of mammalian genomes Behavioral mutations in mouse models Actigraphy studies for sleep/activity patterns Recent Trends Her latest work involves machine learning analysis of actigraphy data for sleep-mortality links, whole-genome sequencing in autism cohorts , and heritability studies of sleep-wake traits using twin data. Collaborations include the Center for Autism Research and iPSYCH Consortium . Outreach Dr. Bucan engages in educational outreach , partnering with Philadelphia high schools to teach sleep/activity studies through hands-on science projects.

Marisa S. Bartolomeiمشاهده پروفایل

استاد

• Genomic Imprinting
• X Chromosome Inactivation
• Epigenetics
• +۴ مورد دیگر

Marisa S. Bartolomei , PhD, is a Perelman Professor of Cell and Developmental Biology and Professor of Genetics at the University of Pennsylvania Perelman School of Medicine . She serves as Director of the IRM Program in Reproductive Medicine and Co-Director of the Epigenetics Institute . Education: B.S. in Biochemistry from the University of Maryland (1982), Ph.D. in Biochemistry from Johns Hopkins University (1987) under Dr. Jeffry Corden, and postdoctoral work in Molecular Biology at Princeton University with Dr. Shirley Tilghman (1988-1993). Her research focuses on genomic imprinting and X inactivation in mice, exploring mechanisms of allelic expression, DNA methylation, and environmental impacts via Assisted Reproductive Technologies (ART) and endocrine disruptors . Key projects include analyzing mutations at imprinted loci, noncoding RNAs at the H19/Igf2 locus, and DNA methylation reprogramming in germ cells. Publications (15 most recent) span epigenetics, developmental biology, and environmental impacts on gene regulation. Notable trends include studies on TET proteins , CTCF insulator function , and ART-induced placental defects . Her work intersects with reproductive medicine and environmental health. Scientific Awards: None explicitly listed in the provided text. She mentors graduate students and postdoctoral fellows, with lab personnel including Aimee Juan, YeeHoon Foong, Joanne Thorvaldsen, and Rexxi Prasasya. Her lab employs mouse models to study epigenetic mechanisms, with collaborations across institutions like Duke University and the NIEHS TaRGET II Consortium.

Brian D Ackleyمشاهده پروفایل

استاد

• Neurobiology
• Synaptic Development
• Host-Pathogen Interactions
• +۳ مورد دیگر

Brian D Ackley is a Professor in the Department of Molecular Biosciences at the University of Kansas , where he also serves as Co-Director of the Undergraduate Biology Program, Director of the NIH-funded Chemistry-Biology Interface Graduate Training Program (T32), and Campus Coordinator for the Kansas IDeA Network for Biomedical Research Excellence (K-INBRE). His research spans three primary areas: Synapse Dynamics : Investigating adhesion proteins (e.g., nidogen, LAR receptor) and calcium channels in synapse formation/elimination balance Neurodegenerative Disease Models : Developing early-onset C. elegans models for Alzheimer's and tauopathies, uncovering non-amyloid mechanisms in familial AD Host-Pathogen Evolution : Analyzing genetic adaptations in C. elegans isolates to understand immune response diversity His work utilizes Caenorhabditis elegans as a model system with genetic mapping, fluorescent imaging, and collaborative biochemical approaches. Publications demonstrate interdisciplinary focus across Neuroscience , Molecular Genetics , and Developmental Biology . Teaching includes advanced neurobiology courses and research mentorship for trainees at all levels. Education : PhD in Neuroscience, Northwestern University (2001) B.A. in Chemistry and Psychology, Virginia Tech (1994) Postdoctoral Training at University of Illinois Chicago and UC Santa Cruz Research Highlights : Discovered calcium channel's role in suppressing synaptic overgrowth from adhesion protein loss Elucidated Flamingo receptor's non-autonomous regulation of inhibitory neuron synapses Developed first C. elegans models showing age-dependent synaptic degeneration Collaborated with Wolfe and Gamblin labs to challenge amyloid hypothesis in Alzheimer's Technical Expertise : Genetic manipulation, fluorescent protein imaging, transcriptional profiling, and cross-species comparative analysis.

Shuo Linمشاهده پروفایل

استاد

• Developmental Biology
• Genetics
• Molecular Biology
• +۹ مورد دیگر

Shuo Lin is a Professor in the Department of Molecular, Cell and Developmental Biology at UCLA since 2001, with a focus on zebrafish genetics to study hematopoietic and vascular development , pancreas organogenesis , and chemical genetics . He earned his Ph.D. in Biological Chemistry from Boston University in 1991, followed by postdoctoral work at MIT. His lab develops zebrafish as a model organism for human disease and drug discovery. Research interests include: Genetic pathways of hematopoiesis and vasculogenesis , emphasizing hemangioblast determination and lineage specification . Genetic basis of pancreatic organogenesis , particularly beta cell development for diabetes research. Pre-clinical drug discovery using zebrafish models for cancer and neurodegenerative diseases . His lab pioneered genome-wide mutagenesis via retroviral insertions and BAC transgenesis with GFP/RFP reporters , generating hundreds of transgenic lines for tissue-specific gene expression. Publications span developmental biology , genetics , and nano-EHS studies , often involving high-throughput screening and transgenic zebrafish models . Graduate students Haishan Zhao and Jason Ear are part of his team. His work integrates biomedical research , transgenesis , and chemical genetics to address fundamental questions in developmental biology and disease modeling.

Allan Mackenzie-Grahamمشاهده پروفایل

استادیار

• Neuroscience
• Neuroimaging
• Neuroimmunology
• +۳ مورد دیگر

Allan Mackenzie-Graham is an Assistant Professor at the University of California, Los Angeles (UCLA) with affiliations in Neurology and Neuroscience. His research focuses on neuroimaging, neuroimmunology, and neurodegenerative diseases, particularly multiple sclerosis and sex-based differences in brain anatomy. His work integrates computational biology, magnetic resonance imaging (MRI), and preclinical models to explore neuroprotective mechanisms and pathological processes. Research Interests: His studies span neuroimaging methodologies (e.g., voxel-based morphometry, CLARITY), hormonal therapies (e.g., estriol, estrogen receptors), and sex differences in neurodegenerative diseases. Key topics include axonal injury, brain atrophy, and neuroinflammatory processes, often using mouse models to bridge bench-to-bedside applications. Publications: Recent work highlights computational advancements in brain segmentation, hormonal neuroprotection in multiple sclerosis, and cross-species neuroimaging comparisons. Projects involve machine learning (e.g., SwinUNETR), neuroanatomical sex differences, and in vivo/ex vivo MRI analysis.

Stephanie Whiteمشاهده پروفایل

استاد

• Vocal Learning
• Social Neuroscience
• Behavioral Genetics
• +۵ مورد دیگر

Stephanie White , a Professor in the Department of Integrative Biology & Physiology at the College of Life Sciences , University of California, Los Angeles, investigates the interplay between social behaviors and neuronal plasticity in zebra finches . Her research focuses on how vocal learning—a critical reproductive behavior—is shaped by gene expression and neural circuitry, particularly through comparative studies of sexually dimorphic brain structures. Her recent publications highlight diverse research directions, from genomic analyses of domestication syndrome in songbirds to RNA diagnostics and clinical implications in neurodevelopmental disorders . Collaborative studies include FOXP2 transcriptional targets and microRNA regulation in vocal learning . Stephanie’s lab employs behavioral experiments , electrophysiology , and molecular techniques to explore how social interactions modulate gene expression and neural properties. She also contributes to interdisciplinary discussions on genetics in palliative care and terminology standardization in genomics . Contact: sawhite@ucla.edu | Lab Website

Hume Akahori Stroudمشاهده پروفایل

استادیار

• Epigenetic gene regulation
• Transposon silencing
• Transcriptional programs
• +۶ مورد دیگر

Hume Akahori Stroud is an Assistant Professor in the Department of Neuroscience at UT Southwestern Medical Center . He earned his B.A. from Cornell University and completed his Ph.D. at the University of California, Los Angeles, working on plant transposon regulation under Dr. Steven E. Jacobsen . His postdoctoral research at Harvard Medical School with Dr. Michael E. Greenberg focused on neuronal development. Education B.A., Cornell University Ph.D., University of California, Los Angeles Postdoctoral Research, Harvard Medical School The Stroud Lab investigates epigenetic gene regulation mechanisms in health and disease, particularly in neurological disorders and cancer . His research bridges plant epigenetics and mammalian neuronal epigenetics, focusing on DNA methylation, histone variants, and chromatin remodeling. His recent publications highlight studies on MeCP2 function in neuronal enhancers , microRNA-29 in brain maturation , and transcriptional transitions in postnatal neurons . Earlier work includes plant epigenetics, such as transposon silencing and histone variant roles in DNA methylation . Current projects in the lab explore how epigenetic disruptions affect neural circuits and contribute to disease, leveraging advanced genomic tools to map activity-dependent regulatory elements and develop cell-type-specific viral vectors.

Stefan Richterمشاهده پروفایل

استاد

• Crustacean Evolutionary Morphology
• Phylogenetic Systematics
• Comparative Neuroanatomy
• +۳ مورد دیگر

Prof. Dr. Stefan Richter is a faculty member at the University of Rostock , affiliated with the Institute of Biosciences under the Faculty of Mathematics and Natural Sciences . His research focuses on General and Special Zoology , with significant contributions to crustacean morphology, phylogenetic systematics, neuroanatomy, and evolutionary biology. Research Interests : Crustacean evolutionary morphology, phylogenetic methodologies, comparative neuroanatomy, biogeography, and evolutionary developmental biology. Contact : Universitätsplatz 2, 18055 Rostock, Germany | Tel: +49 381 / 498-6260 | Email: stefan.richter@uni-rostock.de His work explores the interplay between morphological adaptation, genetic variation, and evolutionary constraints across diverse crustacean groups, including decapods, branchiopods, and malacostracans. Recent studies examine limb asymmetry in hermit crabs, compound eye evolution in prawns, and mitochondrial genomic insights into mountain shrimps. Richter actively contributes to debates on homology concepts and character dependency frameworks in phylogenetic analysis. Key publication trends include: Evolutionary Morphology of crustacean appendages (maxillipeds, chelae, thoracopods) Phylogenomics of Malacostraca and Branchiopoda Neuroanatomical Studies in Cephalocarida and Mystacocarida Biogeographical Investigations of Tasmanian freshwater species Methodological Advances in character dependency analysis Debates on homology, synapomorphy, and evolutionary concepts He serves on editorial boards and participates in academic governance, emphasizing interdisciplinary approaches to understanding crustacean evolution and its broader implications for arthropod systematics.

Nicholas Cianciottoمشاهده پروفایل

استاد

• Bacterial Pathogenesis
• Infectious Diseases
• CRISPR-Cas Systems
• +۴ مورد دیگر

Nicholas Cianciotto is a Professor in the Department of Microbiology and Immunology at Northwestern University Feinberg School of Medicine. He received his PhD from the University of Washington in 1986 and completed postdoctoral training at the University of Michigan. His research focuses on the molecular pathogenesis of Legionella pneumophila and Stenotrophomonas maltophilia , emphasizing virulence factors, protein secretion systems, and iron acquisition mechanisms. His laboratory investigates how these pathogens interact with both amoebae and human cells, leveraging multi-omics approaches to uncover novel therapeutic targets. Current projects include structural analysis of secretion systems, characterization of rhizoferrin's role in biofilm formation, and CRISPR-Cas system evolution beyond phage immunity. Scientific Awards & Leadership: Faculty Service Award, Driskill Graduate Program (2020) Teaching Award, Department of Microbiology-Immunology (2018) Fellow of the American Academy for Microbiology (2008) Outstanding Teacher Award, Feinberg School (2008) Dr. Cianciotto has mentored over 60 researchers, including 20 PhD students, and directs an NIH-sponsored training grant in Immunology and Microbial Pathogenesis. His work has been published in top-tier journals like Nature Microbiology and PLoS Pathogens .

Leonardo Joمشاهده پروفایل

پژوهشگر

• Plant Development
• Bioinformatics
• Functional Genomics
• +۴ مورد دیگر

Dr. Leonardo Jo is a postdoctoral researcher at Utrecht University's Plant Ecophysiology Group, focusing on gene regulatory mechanisms in plant development. He holds a PhD in Plant Biology from the University of California Davis, where his dissertation explored transcriptional networks controlling soybean seed development, and a Master's degree in Biotechnology from the University of Sao Paulo, Brazil. Current Researcher at Utrecht University (November 2021–Present) PhD in Plant Biology (2021), University of California Davis Ms.C. in Biotechnology (2012), University of Sao Paulo, Brazil BS in Biological Sciences (2008), University of Sao Paulo, Brazil Leonardo's research expertise spans Plant Development , Bioinformatics , and Mechanisms of Gene Regulation , with a focus on transcription networks and somatic embryogenesis. His work combines experimental and computational approaches to study gene regulation in plant development, particularly in soybean seed biology and Brazilian pine somatic embryogenesis. His publication record includes studies on proteomic analysis, polyamines, and reactive oxygen species in Brazilian pine embryogenic cultures, comparative transcriptomics in pine embryos, and combinatorial interactions of transcription factors in soybean seed development. He has presented at international conferences such as the Plant Biology Retreat, American Society of Plant Biologists Meeting, and Plant and Animal Genomes. CNPq - National Council for Scientific and Technological Development (Brazil) grant (2007-2009) CAPES grant for graduate studies in Brazil (2009-2011) LASPAU Science without Borders program (2014-2018) Elsie Taylor Stocking Memorial Fellowship (2017-18) Professors for the Future Fellowship, UC Davis (2018-2019) Walter R. and Roselinde H. Russell Fellowship (2019-2020) Student Travel Grants and Best Poster Award (2011-2018) As an educator, Leonardo served as Main Lecturer for UC Davis courses on plant development and professional English presentations and has held teaching assistant roles for plant physiology and genetic engineering courses. He is actively involved in the Kajala Lab at Utrecht University, where he investigates gene regulatory networks in plant development under fluctuating environments, supported by NWO grant VI.Vidi.193.104.

Debbie Thurtle-Schmidtمشاهده پروفایل

استادیار

• Genomics
• Bioinformatics
• Transcriptional Regulation
• +۲ مورد دیگر

Debbie Thurtle-Schmidt is an Assistant Professor in the Biology and Genomics departments at Davidson College. Her research focuses on transcriptional regulation and cellular differentiation in C. elegans , utilizing genomic and genetic approaches to understand how cells develop distinct identities. She can be reached at dethurtleschmidt@davidson.edu or by phone at 704-894-2640. Postdoctoral Studies: University of California, San Francisco (Cellular Molecular Pharmacology) Ph.D.: University of California at Berkeley (Molecular and Cell Biology) B.S.: Santa Clara University (Biology) Dr. Thurtle-Schmidt's work explores genomic regulation in developmental contexts, with particular emphasis on: Transcriptional control mechanisms Epigenetic regulation in cell differentiation Computational analysis of genomic data Environmental influences on gene expression Her recent publications (2020-2024) demonstrate expertise in multi-omics integration , CRISPR technology , and machine learning applications to genomic data, with a focus on C. elegans as a model system. Teaching responsibilities include: BIO 309 Genomics BIO 343 Laboratory Methods in Genomics BIO 240 Biostatistics for Life Scientists BIO/CSC 209 Bioinformatics Programming BIO 115 Molecule, Genes & Cells (+lab) Research is conducted in Wall 325 - Research Lab, with office location at Wall 327.

• Animal Breeding
• Quantitative Genetics
• Genomics
• +۵ مورد دیگر

Mario Calus is a Full Professor in Animal Breeding and Genetics at Wageningen University, specializing in genomics and quantitative genetic modeling. His work focuses on genomic prediction, genetic correlation, and selection strategies to improve animal breeding programs. Current affiliations: Animal Breeding and Genetics Group, WIAS Research themes: Integrating DNA methylation into genetic models, multi-population genomic data analysis, and conservation genetics of endangered breeds. Recent research explores heat stress impacts on dairy cattle fertility, Bayesian selection methods, and functional omics in genomic prediction. His projects include collaborations with institutions across Europe, emphasizing precision breeding and crossover utilization in livestock. His research trends highlight advancements in genomic prediction accuracy through multi-population datasets, epigenetic mechanisms in inheritance, and innovative selection strategies beyond traditional breeding values. Key subfields include DNA methylation dynamics, conservation genetics, and multi-trait genomic models. He supervises PhD candidates like Jeremie Vila I Teixidor and O. Katz, guiding projects on genetic gain optimization and environmental covariates in maize breeding. Calus actively contributes to academic discourse through keynote lectures and peer-reviewed publications.

Donald F. Conradمشاهده پروفایل

دانشیار

• Human genetics
• DNA mutation
• Infertility
• +۴ مورد دیگر

Donald F. Conrad is an Associate Professor in the Department of Genetics at Washington University in St. Louis and serves as Chief of the Division of Genetics at the Primate Center at OHSU, where he was recruited in 2018. As a human geneticist with over 15 years of experience, Dr. Conrad has developed both statistical and experimental methods for genome analysis, with particular focus on male infertility and testis biology. Key research areas: Male infertility genetics Testis biology and spermatogenesis Genome biology of germ cells Single-cell genomics and RNA sequencing Development of computational tools for mutation detection (DeNovoGear) Development of automated image analysis tools for testis histology (SATINN) Analysis of postzygotic mutations in human tissues Based on recent publications, Dr. Conrad's research spans multiple areas of genetics with particular emphasis on male reproductive health. His work has led to the identification of novel genetic causes of male infertility and the development of computational tools to analyze these genetic phenomena. Scientific awards: Fulbright Specialist Grant (2017) Finalist for Postdoctoral Trainee (Basic) award, ASHG (2008) Best Dissertation in Biological Sciences (honorable mention), The University of Chicago (2008) Dr. Conrad's laboratory continues to be at the forefront of developing methodologies for analyzing genetic variation and its impact on reproductive health, with significant contributions to our understanding of the genomic basis for male infertility.

• Plant Genetics
• Genomics
• Plant Domestication
• +۵ مورد دیگر

Dr. Gabriella Sonnante is a Research Director at Italy's National Research Council (CNR), leading research programs at the Institute of Biosciences and Bioresources (IBBR) in Bari. With over 25 years at CNR, she has progressed from Researcher to Senior Researcher before assuming her current leadership role in 2021. She holds a Biology degree from the University of Bari and has conducted research internationally at institutions including UC Davis, John Innes Centre, and University of Frankfurt. Her research focuses on plant molecular evolution, domestication processes, and genetic resource characterization, utilizing molecular markers (SNP, SSR, AFLP), genomics, and transcriptomics. Key species in her studies include wheat, legumes, and globe artichoke, with emphasis on genes involved in polyphenol synthesis, nitrogen utilization, and abiotic stress responses. She manages the Cynara (artichoke) germplasm collection and studies genetic diversity conservation in agricultural systems. Her extensive publication record demonstrates consistent focus on crop genetics and genomics, with recent work emphasizing molecular characterization of traditional landraces, stress-responsive genes in wheat, and biodiversity conservation in Mediterranean crops. Research frequently integrates advanced techniques like NMR metabolomics, SNP genotyping, and whole-genome analysis. Dr. Sonnante serves on the PhD teaching faculty at the University of Bari (PhD program: 'Biodiversity, Agriculture and Environment') and represents CNR in the European Plant Science Organization. She leads multiple national and EU-funded projects including Agritech National Research Center (PNRR), BiodiverSO (Puglia region), and PON ALIFUN on functional foods.

Esperanza Rivera de Torreمشاهده پروفایل

استادیار

• Antibody Engineering
• Venomics
• Antivenom Development
• +۷ مورد دیگر

Esperanza Rivera de Torre is an Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark. Her research focuses on antibody engineering, venomics, and protein design, particularly in neutralizing venom toxins and cancer therapy. Current affiliation: Department of Biotechnology and Biomedicine (DTU) Academic rank: Assistant Professor Research Interests Specializing in antibody engineering to develop synthetic antivenoms using de novo protein design. Investigating snake venom toxins and their neutralization mechanisms via VHH antibodies. Contributing to protemics and peptide sequencing through AI-driven tools like InstaNovo. Studying structural biology of actinoporins and their interactions with lipid membranes. Active in cross-neutralizing antibodies for tropical diseases and allergens. Advising and Collaborations Supervises multiple PhD students including Ruiz Espi, Møller, and Møiniche. Collaborates on projects like AI-driven protein binder design and allergen epitope characterization. Engages in international collaborations across venom and biomedical research fields.