جستجوی استاد راهنمای دانشگاهی

Xenia Kobelevaمشاهده پروفایل

استاد

• Computational Neuroscience
• Neuropsychiatry
• Machine Learning in Neuroimaging
• +۵ مورد دیگر

Prof. Dr. Xenia Kobeleva serves as Professor and head of the Department of Neurostimulation within the Faculty of Medicine at Ruhr University Bochum (RUB). She concurrently leads the Computational Neurology Research Group, directing interdisciplinary efforts at the intersection of computational science and clinical neuropsychiatry. Her research program focuses on developing and applying computational methodologies—including machine learning, artificial intelligence, and whole-brain network modeling—to analyze clinical and neuroimaging data. This dual approach of data-driven and theory-based modeling aims to decode pathophysiological mechanisms in neuropsychiatric disorders, with direct translational goals for neurostimulation-based diagnostics and therapies. Key application areas include Alzheimer's disease, Lewy body dementia, amyotrophic lateral sclerosis (ALS), and movement disorders. Analysis of her 2016-2024 publications reveals a consistent trajectory in computational neurology, characterized by innovative network-level analyses of neurodegenerative conditions. Her work demonstrates particular expertise in integrating multimodal neuroimaging with advanced modeling techniques to identify disease-specific biomarkers and network alterations, bridging computational neuroscience with clinical practice. Prof. Kobeleva directs both the Department of Neurostimulation and Computational Neurology Research Group at RUB, fostering collaboration between neurologists, psychiatrists, computer scientists, and engineers. These teams operate from room MB 6/189 at Universitätsstraße 150 in Bochum, developing computational tools and neurostimulation protocols for neuropsychiatric disorders.

Markus Reichertمشاهده پروفایل

استاد

• Systems Neuroscience
• Sport Science
• Ambulatory Assessment
• +۳ مورد دیگر

Markus Reichert is a Professor at the Department of eHealth and Sports Analytics, Faculty of Sports Science, Ruhr University Bochum. His research integrates systems neuroscience, sport science, and digital health to study neural mechanisms underlying physical behavior and its impact on mental health and well-being. Focus on ambulatory assessment and neuroimaging Interdisciplinary approach combining geoinformatics and epidemiology Investigates real-life effects of urban green spaces and sedentary behavior His recent work explores the interplay between nonexercise activity, affective states, and psychiatric resilience, utilizing ecological momentary assessment (EMA) and functional MRI. Publications highlight the neural correlates of mood changes linked to physical activity and environmental factors during the pandemic. Collaborates with neuroscientists, psychologists, and data scientists Applies mobile sensors (accelerometers, glucose sensors) for behavioral monitoring

Patrizia Thomaمشاهده پروفایل

استاد

• Social Cognition
• Neuropsychology
• Clinical Neuropsychology
• +۷ مورد دیگر

Prof. Dr. Patrizia Thoma serves as Professor at the Institute of Cognitive Neuroscience within the Faculty of Psychology at Ruhr University Bochum. She leads the Clinical Neuropsychology Workgroup and co-directs the Neuropsychological Therapy Centre, providing diagnostics and therapy for cognitive-affective impairments following acquired brain damage. Her research investigates neurocognitive mechanisms of altered social cognition across psychiatric disorders (alcohol dependence, depression) and neurological conditions (stroke, traumatic brain injury, brain tumors). Key foci include emotion recognition, empathy, and social problem solving, with emphasis on differentiating impairment profiles between patient groups and developing internet-based diagnostic/therapeutic tools like the 'SoCoBo' online therapy platform. Recent publications (2020-2024) reveal intensive development of technology-assisted interventions for sociocognitive deficits, featuring randomized trials of digital therapies, systematic reviews of telemedicine applications, and specialized studies on brain tumor and traumatic brain injury populations. This work demonstrates strong translational movement from basic social cognition mechanisms to clinical rehabilitation tools. Prof. Thoma actively trains psychological psychotherapists to become clinical neuropsychologists through the Neuropsychological Therapy Centre. Her research integrates clinical service delivery with experimental investigation, maintaining direct connections between patient care and scientific advancement in neurorehabilitation.

• Neurodegenerative Diseases
• Translational Medicine
• Molecular Pathophysiology
• +۷ مورد دیگر

Prof. Dr. Dr. Andreas Hermann is a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Rostock, Germany. He specializes in bidirectional translation between basic research and clinical applications, focusing on neurodegenerative diseases. Location: Gehlsheimer Str. 20, 18147 Rostock Email: andreas.hermann@dzne.de Phone: +49 381 494-9541 Research Interests His work emphasizes hypothesis-driven molecular pathophysiology studies in ALS/FTD (particularly FUS-ALS), Huntington’s Disease (HD), Parkinson’s Disease (PD), and VPS13opathies. Key areas include: Pathophysiology-guided drug development Multi-modal biomarker discovery (serum/CSF, MRI, PET, behavioral endophenotypes) Characterization of prodromal neurodegenerative states Interaction of brain reserve, cognitive reserve, and motor reserve Healthy and pathological aging mechanisms Clinical and Patient-Centered Focus The group leads the DESCIBE-ALS cohort, participates in phase 1–3 clinical trials (including antisense oligonucleotides), and investigates quality of life (QoL) in advanced neurodegenerative patients using eye-tracking systems. They are also involved in the Interside project (Next-of-Kins studies in FTD) and the PROSA Study (digital speech biomarkers for ALS/FTD clinical trials). Human Cell Models They develop patient-derived iPSC cultures and fibroblast models integrated with clinical data, biomaterials, and postmortem tissue. Research explores mitochondrial dysfunction, axonopathy, DNA damage, retrotransposon activation, and cell-intrinsic immune responses.

• Neurodegenerative Diseases
• Parkinson's Disease
• Stem Cell Therapy
• +۳ مورد دیگر

Prof. Dr. Alexander Storch serves as a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Rostock, Germany, focusing on non-motor symptoms in movement disorders including Parkinson's disease and amyotrophic lateral sclerosis (ALS), with particular emphasis on cognitive dysfunctions. His research group integrates learning and memory assessments with functional and morphological neuroimaging to characterize cognitive impairments in neurodegenerative conditions. Concurrently, they pioneer regenerative therapies for Parkinson's disease through stem cell-based approaches, examining fetal tissue-specific neural stem cells, adult neural stem cells, and bone marrow-derived stem cells for proliferation, differentiation into dopaminergic neurons, and mechanisms governing predopaminergic progenitor specification. Their work explores adult neurogenesis in healthy and diseased states to identify endogenous regeneration targets, alongside in vivo studies optimizing biopolymer-assisted stem cell transplantation for nigrostriatal pathway reinnervation. The Storch group operates within DZNE's research framework, conducting translational studies that bridge fundamental stem cell biology with therapeutic applications for neurodegenerative disorders.

• Glia biology
• Myelin
• Neurodegeneration
• +۵ مورد دیگر

Professor Mikael Simons is a leading neuroscientist and W3 Professor at the Technical University Munich's Faculty of Medicine, where he serves as Director of the Institute of Neuronal Cell Biology. He also holds prominent positions at the German Center for Neurodegenerative Diseases (DZNE) in Munich, including Head of Clinical Research & Clinical Trial Unit since 2020. His laboratory is located at the Center of Stroke and Dementia Research at Campus Grosshadern in Munich and maintains strong affiliations with multiple research institutions including the Institute for Stroke and Dementia Research. Prof. Simons completed his medical education at the University of Heidelberg in 1997, earning his MD thesis 'summa cum laude' under Prof. Dr. Konrad Beyreuther. He completed his neurology residency at the University of Tübingen, where he also earned his Facharzt qualification in Neurology in 2004 and Habilitation in Neurology in 2005. His research focuses on the biology of glial cells, particularly oligodendrocytes and microglia, and their roles in nervous system function and disease. Key research areas include myelin formation and regeneration, white matter aging, neuroinflammation, and the role of lipoproteins in neurodegenerative diseases. His laboratory combines genetic, molecular, biochemical, and advanced imaging techniques to investigate these processes in physiological and pathological contexts. Analysis of Prof. Simons' recent publications reveals a strong focus on the intersection of glial biology and neurodegenerative diseases, particularly Alzheimer's disease and multiple sclerosis. His work demonstrates how myelin dysfunction contributes to amyloid-beta pathology and how microglial responses to white matter aging drive neurodegeneration. The research spans multiple model systems including mice, zebrafish, and human iPSC-derived cells, utilizing cutting-edge techniques like single-cell genomics, CRISPR/Cas9 screening, and advanced electron microscopy. National award for the best MD thesis in Germany (1995) EMBO Young Investigator Award (2008) Multiple ERC grants including Starting, Consolidator, and Advanced Grants Ilse & Hans Breuer Award for Alzheimer Disease Research (2014) Election to the German National Academy of Sciences Leopoldina (2023) Prof. Simons leads a substantial research team including multiple postdocs, PhD students, technicians, and clinical researchers. He has secured significant funding through collaborative research centers (TRR 274), the Adelson Medical Research Foundation, and the Chan Zuckerberg Initiative. His laboratory is part of several hubs including the Electron Microscopic Hub and Single-cell Transcriptome Hub, reflecting the interdisciplinary nature of his work. The lab actively investigates how glial cells contribute to brain function and how their dysfunction leads to disease, with particular emphasis on myelin biology and neuroinflammation in neurodegenerative conditions.

• Atherosclerosis
• Cardiovascular Disease
• Macrophage Biology
• +۳ مورد دیگر

Professor Erik Biessen is a cardiovascular research scientist affiliated with the Institute for Molecular Cardiovascular Research (IMCAR). His work focuses on molecular mechanisms underlying atherosclerosis, macrophage biology, lipid metabolism, and inflammation. He leads studies on proteoglycan signaling, chemokine networks, and metabolic reprogramming in cardiovascular pathologies. Key Research Areas Atherosclerosis mechanisms and plaque vulnerability Macrophage heterogeneity in cardiovascular disease Lipidomics and uremic toxin interactions Role of microRNAs and metabolic networks Recent Article Trends Studies on cathepsin D inhibition in liver lipidomics (2025) MicroRNA-26b's protective role in MASH (2025) Investigations into glutamine metabolism's impact on plaque inflammation (2024) Chemokine CCL18's role in T-cell infiltration (2024)

• Psychiatry
• Neuroscience
• Digital Health
• +۲ مورد دیگر

Dr. Markus Reichert serves as a Junior Professor and Visiting Scientist at the Central Institute of Mental Health, Mannheim within the Clinic of Psychiatry and Psychotherapy. His work bridges clinical psychiatry with advanced computational and neuroscience methodologies through two dedicated research groups. His research focuses on real-world mental health dynamics using mobile health (mHealth) technologies and systems neuroscience. Key interests include neural correlates of social interactions, urban environmental impacts on affect, hormonal influences on addictive behaviors, and exercise-cognition relationships in eating disorders. He pioneers ecological momentary assessment techniques to capture real-life behavioral and physiological data outside laboratory settings. Analysis of his 2019-2024 publications reveals a cohesive trajectory examining how everyday experiences—from social contact to green space exposure—modulate neural activity and psychiatric resilience. His work consistently integrates neuroimaging (fMRI), real-world monitoring, and sex-specific analyses to uncover biological mechanisms underlying mental well-being and disorder. Dr. Reichert leads the mHealth methods in psychiatry research group and the Systems Neuroscience Psychiatry (SNiP) group, driving innovation in digital phenotyping and neural circuit analysis for psychiatric applications. His collaborative approach spans multi-center studies across European institutions, emphasizing translational impact for clinical practice.

• Epidemiology
• Biometrics
• Public Health
• +۳ مورد دیگر

Rafael T Mikolajczyk serves as Full Professor of Epidemiology and Biometrics and Director of the Institute for Medical Epidemiology, Biometrics and Informatics at Martin-Luther-University Halle-Wittenberg's Medical School. With over 307 publications spanning decades, he leads major epidemiological initiatives including the German National Cohort and DigiHero studies. His research interests focus on vaccination science (COVID-19, influenza, hepatitis B), chronic disease epidemiology (cancer, diabetes), and health services research . Recent work examines regional healthcare disparities, biomarker validation, and innovative risk communication methods, consistently applying rigorous cohort and mixed-methods approaches. Analysis of his 2022-2024 publications reveals strengthening focus on global vaccine implementation (Indonesia collaborations), real-world emergency care data , and patient-centered risk communication . His work bridges biostatistical methodology with actionable public health interventions across German and international contexts. Scientific contributions include: Leadership in Germany's largest population cohorts Methodological advances in vaccination uptake research Development of evidence-based risk communication tools Identification of early-life diabetes risk factors His institute drives epidemiological training and medical informatics innovation at Halle Medical School, with active grants supporting vaccination studies, cohort analyses, and health services research. Current projects involve international teams across Germany, Indonesia, and European networks, maintaining high publication output in top public health journals. The Institute for Medical Epidemiology, Biometrics and Informatics operates as an interdisciplinary hub connecting clinical departments, public health agencies, and international research consortia under his directorship, focusing on translating epidemiological findings into health policy improvements.

• Neuropsychiatric Disorders
• Developmental Neurobiology
• Serotonin Signaling
• +۳ مورد دیگر

Mark Ansorge , PhD, is Associate Professor of Clinical Neurobiology (in Psychiatry) at Columbia University's College of Physicians and Surgeons. His research investigates developmental origins of neuropsychiatric disorders through multi-disciplinary approaches integrating mouse genetics , pharmacogenetics , and optogenetics . Education : MS in Biochemistry (University of Potsdam, Germany), PhD in Neurobiology (Free University of Berlin, Germany), Postdoc (Columbia University, USA) Dr. Ansorge's work focuses on serotonin signaling during critical developmental windows and its long-term impacts on emotional and cognitive behaviors. His lab has demonstrated that early-life perturbations in 5-HT systems lead to persistent changes in raphe nuclei , hippocampus , and medial prefrontal cortex circuitry, linking these alterations to increased adult vulnerability for depression and anxiety disorders . Recent publications highlight his expanding scope into gut-brain axis interactions (2025) and adolescent dopamine transporter manipulation (2023). While primarily using mouse models , his work maintains translational relevance through collaborations with clinical researchers.

• Cognitive Psychology
• Executive Control
• Volition
• +۴ مورد دیگر

Professor Thomas Goschke is a full-time faculty member at Dresden University of Technology, where he holds the Chair of General Psychology within the Faculty of Mathematics and Natural Sciences. His research examines cognitive control mechanisms through interdisciplinary approaches. Research Focus: Goschke's work spans: Volitional dysfunctions in addiction and everyday behavior Neurocomputational modeling of cognitive control Dynamic interactions between executive functions Emotion-cognition interactions Implicit learning systems Grant Leadership: He has directed major DFG-funded initiatives including: Collaborative Research Center 940 (Volition and Cognitive Control) Priority Program on executive control mechanisms Transregio project on cognitive mediators of drinking behavior International Research Training Group on affective disorders His lab employs behavioral paradigms, neuroimaging, and computational modeling to investigate cognitive flexibility, intention shielding, and reward processing.

• Neuroscience
• Neural Stem Cell Research
• Brain Regeneration
• +۵ مورد دیگر

Professor Federico Calegari is a leading neuroscience researcher at Dresden University of Technology's Center for Regenerative Therapies Dresden (CRTD), where he serves as a Professor conducting cutting-edge research in neural stem cells, brain regeneration, and cognitive function. His work bridges fundamental neuroscience with translational applications for neurological disorders. His primary research interests include neural stem cell biology, mechanisms of neurogenesis, cortical development, and therapeutic approaches for neurological conditions including age-related cognitive decline, stroke recovery, and neurodegenerative diseases. Dr. Calegari's work particularly focuses on the inducible expansion of neural stem cells and their therapeutic potential for brain repair. Analysis of his recent publications reveals a strong emphasis on molecular mechanisms controlling neural development, with increasing focus on translational applications. His work spans from basic research on cortical development and neural circuit formation to therapeutic approaches for conditions like ALS, stroke, and cognitive impairment. A significant portion of his recent work involves gene therapy approaches and RNA regulation in neural systems. Dr. Calegari has received substantial research funding from the German Research Foundation (DFG) for multiple projects, including cluster funding for the Center for Regenerative Therapies Dresden. His research program demonstrates a clear trajectory from fundamental mechanisms to potential therapeutic applications. His laboratory appears to focus on both in vitro and in vivo approaches to study neural development and regeneration, with particular expertise in stem cell manipulation, neural circuit analysis, and molecular regulation of neurogenesis. The breadth of his funded projects suggests a highly productive research environment with multiple active research lines.

Tatiana Korotkovaمشاهده پروفایل

استاد

• Neuronal circuits
• Innate behaviors
• Feeding behaviors
• +۱۰ مورد دیگر

Prof. Dr. Tatiana Korotkova serves as Professor, Principal Investigator, Institute Director, and Head of Research Area 3 at the Institute for Systems Physiology & Pathophysiology within the Faculty of Medicine at University of Cologne. She leads the Neuronal Circuits and Behavior research group, which focuses on understanding how neuronal circuits regulate innate behaviors including feeding, social interaction, arousal, and voluntary locomotion. Dr. Korotkova's research program aims to decode functions of hypothalamic neuronal circuits in health, disease, and aging. Her laboratory combines state-of-the-art technologies including multisite high-density neuronal recordings in transgenic behaving mice, optogenetics, chemogenetics, and computational approaches to investigate neuronal mechanisms of neuropsychiatric disorders associated with hypothalamic dysfunctions. Her work has revealed key insights about how lateral hypothalamus regulates feeding behavior, social interactions, and exploration, with specific findings about GABAergic neuronal subpopulations that balance nutritional and social needs even under hunger conditions. Analysis of Dr. Korotkova's publication record shows a strong trajectory of high-impact research in neural circuit mechanisms, with consistent publications in top journals including Nature, Nature Neuroscience, and Cell Metabolism. Her work demonstrates an evolving focus from basic circuit mechanisms to translational applications for obesity, sleep disorders, and memory impairments, with increasing attention to how these circuits change during aging and disease states. Dr. Korotkova directs the CurioNeuro laboratory, which investigates changes in neuronal activity in the lateral hypothalamus during aging and how these changes underlie metabolic and sleep disorders common in elderly populations. Her team is actively researching how cognitive and reward-related information is translated to the hypothalamus during innate behaviors, and how this process changes in disease contexts and during healthy aging.

• Neuronal dendrite and synapse development
• Cytoskeletal structure and dynamics
• Cell shape and movement
• +۵ مورد دیگر

Anthony J. Koleske is the Ensign Professor of Molecular Biophysics and Biochemistry and of Neuroscience at Yale University School of Medicine, where he also serves as Deputy Dean for Research (Basic Science). He has held joint appointments in the Department of Molecular Biophysics and Biochemistry (primary) and the Department of Neuroscience (secondary) since joining Yale in 1998. Previously, he served as Director of the combined PhD programs in the Biological and Biomedical Sciences at Yale (2014-2019) and Director of the China Scholarship Council-Yale World Scholars Program (2014-2019). Dr. Koleske's research focuses on understanding the biochemical mechanisms that regulate neuronal dendrite and synapse development, with particular emphasis on cytoskeletal structure and dynamics. His lab investigates how growth factor and adhesion receptors control cell shape, structural stability, and movement, applying these principles to understand cancer cell invasion and neuronal circuit stability in the adolescent brain. Current research initiatives explore how stress and psychostimulant abuse disrupt neuronal structure and connectivity, with translational goals for treating breast cancer, neurodevelopmental disorders, and neurodegenerative diseases. His recent publications reveal significant findings in several key areas: TRIO protein variants linked to autism and schizophrenia spectrum disorders Mechanisms of synapse maturation involving laminin α5 stabilization Abl2 kinase regulation of microtubules and actin dynamics NMDA receptor dysfunction in cognitive impairment Dr. Koleske has received numerous prestigious awards including: Jane Coffin Childs Postdoctoral Fellowship Special Fellowship and Scholar Awards from the Leukemia and Lymphoma Society Young Investigator and Established Investigator Awards from NARSAD Established Investigator Award from the American Heart Association With extensive experience in graduate education, Dr. Koleske has served on numerous review panels including as Chair of the Basic Science Study Section for the American Heart Association and the Neurodifferentiation, Plasticity, Repair, and Rhythmicity Study Section of the NIH. His lab maintains active collaborations across Yale and beyond, with a strong record of mentoring students who go on to distinguished careers. The Koleske Lab is currently recruiting postdoctoral fellows with expertise in protein biochemistry, single molecule biophysics, animal behavior, and electrophysiology to advance research on cytoskeletal mechanisms in neurodevelopmental disorders.

• Breast Cancer
• Medical Oncology
• Cancer Treatment Adherence
• +۵ مورد دیگر

Sarah Elizabeth Schellhorn, MD, is an Associate Professor of Medicine (Medical Oncology) at Yale School of Medicine and serves as Chief Ambulatory Officer of Smilow Cancer Hospital. She is also the Regional Service Line Medical Director for the Central Shoreline Region at Smilow Cancer Hospital. Her clinical practice focuses on breast cancer treatment, and she is actively involved in education of students, residents, and fellows at Yale. Dr. Schellhorn's research interests span breast cancer treatment adherence, healthcare policy, women's health, and elderly cancer care. She leads the Breast Cancer Endocrine Therapy Adherence (BETA) study, which uses digital interventions to improve treatment compliance. Her recent publications (2020-2024) demonstrate a strong focus on breast cancer outcomes research, treatment patterns, and healthcare delivery. Her work often examines age-related biases in treatment decisions, medication adherence strategies, and the real-world effectiveness of breast cancer therapies. Dr. Schellhorn has received multiple teaching awards including the David S. Fischer MD Annual Teaching Award (2016, 2019) and has been recognized for clinical excellence with the Clifton Howe Award (2011). She actively mentors postdoctoral fellows and serves on numerous hospital committees including the Smilow Access Committee and Central Shoreline Planning Committee. Her current research portfolio includes several clinical trials as Principal or Sub-Investigator, with a particular emphasis on optimizing breast cancer treatment through biomarker-guided approaches and improving patient monitoring strategies. She is deeply involved with the COPPER Center (Cancer Outcomes, Public Policy, and Effectiveness Research) at Yale School of Medicine, where she contributes to health policy research in oncology.