جستجوی استاد راهنمای دانشگاهی

Mario A. Svirskyمشاهده پروفایل

استاد

• Auditory Neuroscience
• Cochlear Implants
• Speech Perception
• +۳ مورد دیگر

Mario A. Svirsky is the Noel L. Cohen Professor of Hearing Science and Professor of Neuroscience at NYU Grossman School of Medicine. He leads the Laboratory for Translational Auditory Research, focusing on auditory neural prostheses like cochlear implants and their impact on speech perception and neuroplasticity. His work bridges clinical care and scientific discovery, addressing how the brain adapts to sensory deprivation and degraded auditory input. Education: PhD in Biomedical Engineering from Tulane University (1988). Postdoctoral training at MIT and prior academic appointments at Indiana University and Purdue University before joining NYU in 2005. Research: Explores cochlear implant performance optimization, speech perception in hearing-impaired individuals, and neuroplasticity mechanisms. Collaborates with the Froemke Lab on animal models of cochlear implantation. Active in developing computational models and signal processing techniques to improve implant efficacy. Funding: Principal investigator on multiple NIH grants (e.g., R01 DC016839, R01 DC016834) and industry partnerships. His lab’s work has advanced clinical management strategies for cochlear implant users, including those with contralateral hearing aids. Labs/Teams: Directs the Laboratory for Translational Auditory Research, collaborating with multidisciplinary teams including engineers, neuroscientists, and clinical audiologists. Mentors postdocs, audiologists, and medical students in auditory research.

• Pediatric Otolaryngology
• Stem Cell Therapy
• Regenerative Medicine
• +۸ مورد دیگر

Christian J. Hochstim, MD, PhD, is a Clinical Assistant Professor of Otolaryngology at the University of Southern California. His clinical expertise includes complex airway disorders, pediatric tracheostomy management, and vocal cord paralysis. He completed a pediatric otolaryngology fellowship at Stanford University and earned his PhD in developmental biology at Caltech. His research focuses on regenerative medicine strategies for airway reconstruction and preventing stenosis, leveraging stem cell technology. Dr. Hochstim’s education includes a dual MD/PhD, with postdoctoral training in head and neck cancer at Stanford. His research bridges developmental biology and clinical otolaryngology, addressing challenges in airway reconstruction and pediatric surgical outcomes. His clinical interests span aerodigestive disorders, obstructive sleep apnea, and cochlear implantation. He has published extensively on pediatric tracheostomy quality of life, biofilm-associated stenosis, and disparities in healthcare access. Notable studies include repurposing evolutionary gill gene programs for outer ear development and evaluating opioid-free anesthesia in OSA surgery. Key contributions include analyzing prognostic factors in pediatric fungal rhinosinusitis and investigating respiratory risks in endoscopic procedures. His work emphasizes translational research with clinical impact, particularly in underserved pediatric populations.

Elina Mäki-Torkkoمشاهده پروفایل

استاد

• Audiology
• Hearing Loss
• Cochlear Implants
• +۴ مورد دیگر

Elina Mäki-Torkko is a Professor of Medical Audiology at Örebro University's Department of Medical Sciences, affiliated with the Faculty of Medicine and Health since November 2016. She also leads the Audiology Research Centre at Örebro University Hospital and serves as a Senior Consultant in Audiology there. Additionally, she holds positions as an Associate Professor at the University of Oulu, Finland (since 2007), Visiting Professor at Linköping University (since 2017), and Scientific Advisor in Audiology at Sweden's National Board of Health and Welfare. Her research focuses on auditory epidemiology, particularly age-related hearing loss, and the benefits of cochlear implants in adults. She has led collaborative projects such as the ARHI study investigating genetic and environmental factors in hearing impairment. Her work includes longitudinal studies on cochlear implant outcomes, sensory functioning in aging populations, and the development of clinical tools like the Hearing and Functioning in Everyday Life Questionnaire (HFEQ). She has also contributed to understanding the impact of cardiovascular health on hearing deterioration and noise-induced hearing loss in adolescents. Key collaborations include work with the University of Oulu on epidemiological studies and international projects analyzing tinnitus and hearing aid rehabilitation. Her research emphasizes translational outcomes, aiming to improve clinical practices and patient quality of life through evidence-based interventions.

Ning Chengمشاهده پروفایل

استادیار

• Neurodevelopmental Disorders
• Autism Spectrum Disorder
• Fragile X Syndrome
• +۵ مورد دیگر

Ning Cheng is an Assistant Professor (Teaching & Research) at the University of Calgary's Faculty of Veterinary Medicine, with affiliations to the Alberta Children's Hospital Research Institute (ACHRI) and Hotchkiss Brain Institute (HBI). Their research focuses on neurodevelopmental disorders, particularly autism and Fragile X Syndrome, using rodent models to investigate mechanisms and develop experimental therapeutics. PhD in neuroscience from Johns Hopkins School of Medicine Postdoctoral work on neurological disorders at NIH Research spans molecular mechanisms, neural circuitry, and translational approaches to address social, communication, and behavioral challenges in autism spectrum disorders. The lab utilizes in vivo recording/modulation of brain activity, biochemical analyses, and multidisciplinary collaborations. Recent publications highlight expertise in EEG biomarker discovery, auditory processing abnormalities, ketogenic diet interventions, and ERK pathway modulation in mouse models of neurodevelopmental conditions. Key technologies developed include wireless cortical hemodynamic monitoring systems (TinyIOMS) and open-source electrophysiology tools (OSERR). As part of ACHRI's Precision Medicine & Disease Mechanisms program and HBI's Neurodevelopment/SCNIP strategic initiatives, Cheng contributes to university-wide efforts in Brain and Mental Health (2015-2021) and Child Health and Wellness (2020-2025).

John Manakمشاهده پروفایل

استاد

• Genetics
• Neurobiology
• Genomics

John Manak serves as Professor and Biomedical Sciences Program Director in the Department of Biology at the University of Iowa, conducting research at the intersection of genomics, genetics, and neurobiology. His work employs model organisms including Drosophila and Xenopus to investigate human genetic disorders and develop translational therapies. His academic background includes: PhD from Columbia University Dr. Manak's research focuses on identifying causative mutations for congenital anomalies such as spina bifida, branchio-oto-renal syndrome, renal agenesis, and cleft lip/palate. His lab discovered ISM1 as a critical craniofacial patterning gene and elucidated PRICKLE's role in epilepsy-ataxia syndromes using fly models. Current work explores glial immune responses and oxidative stress pathways in seizure progression, with potential for repurposing anti-inflammatory drugs as novel anti-epileptic therapies. Analysis of his 2019-2023 publications reveals consistent emphasis on copy-number variation analysis in craniofacial disorders and epilepsy mechanisms. Key trends include identification of novel clefting genes (COBLL1, RIC1, ARHGEF38), chromatin organization studies involving Dm-Myb, and translational approaches targeting neuroinflammation. His work bridges fundamental genetic discovery with clinical applications through integrated genomic and physiological analyses. No scientific awards were specified in the source material. As principal investigator, Dr. Manak mentors graduate students and postdoctoral researchers while securing research funding evidenced by his publication record in high-impact journals including Nature, PNAS, and Cell Reports. His leadership extends to directing the Biomedical Sciences Program and contributing to departmental research initiatives. His laboratory maintains active research programs utilizing Drosophila for epilepsy modeling, Xenopus for craniofacial studies, and mammalian systems for neuroprotection research. The lab collaborates extensively with University of Iowa core facilities including the Carver Center for Genomics and Carver Center for Imaging, employing techniques ranging from CRISPR-based gene editing to electrophysiological analysis of neural circuits.

Alan Dombkowskiمشاهده پروفایل

استاد

• Molecular Neuroscience
• Genomics
• Bioinformatics
• +۴ مورد دیگر

Alan Dombkowski is a Professor of Pediatrics at Wayne State University School of Medicine, specializing in molecular mechanisms of neurological disorders through genomic and bioinformatic approaches. Key research focus: Epileptogenic potential of cortical tubers in Tuberous Sclerosis Complex (TSC) Methods: Next-gen sequencing, microarrays, proteomics, and epigenetic analysis of human brain tissue Current projects funded by federal grants examining microRNA regulation and therapeutic targets in epilepsy Recent publications span: 2024: Cisplatin-induced cochlear synaptic proteomics 2023: Multi-omic biomarkers for prostate cancer aggressiveness 2021: Exosomal miRNA in TSC epilepsy 2018: Neuroinflammatory mechanisms in pediatric epilepsy Collaborations include Harry Chugani (neuroimaging), Diane Chugani (neurochemistry), Eishi Asano (epileptology), and Paul Stemmer (molecular pharmacology).

• Hearing Science
• Neuroscience
• Otolaryngology
• +۳ مورد دیگر

Liman Liu is an Associate Research Scientist at the Yale School of Medicine, affiliated with the Department of Internal Medicine at Yale University. Their research focuses on auditory system physiology, neurodegenerative diseases, and inner ear biology. Key projects include investigating hearing sensitivity mechanisms, Alzheimer’s disease biomarkers, and the impact of genetic mutations on cochlear function. Research interests span hearing protection mechanisms, genetic influences on auditory disorders, and the intersection of neuroscience with otolaryngology. Notable contributions include studies on Cx26 mutations and hyperacusis, efferent neuron roles in hearing protection, and early Alzheimer’s detection via auditory deficits. Liu’s work integrates molecular biology, electrophysiology, and animal models to address hearing loss and neurodegenerative challenges. Collaborative efforts aim to advance therapies for ototoxicity and neurosensory disorders.

• Biomedical Engineering
• Neuroprosthetics
• Sensory Bionics
• +۳ مورد دیگر

Professor Gregg Suaning is a leading academic in Biomedical Engineering at the University of Sydney, affiliated with the School of Biomedical Engineering, The University of Sydney Nano Institute, and the Brain and Mind Centre. He holds a PhD from UNSW and has over 25 years of experience in implantable neuroprosthetics, focusing on restoring sensory functions for the blind and deaf. His work spans academic and industry roles, including contributions to Cochlear's cochlear implant innovations and pioneering visual prosthetic research. Education: PhD (UNSW, 2003), MSc and BSc (California State University, 1986-1988). Research interests center on developing implantable bionics to restore vision and hearing. Notable projects include the Phoenix 99 suprachoroidal visual prosthesis and facial nerve paralysis interventions. He has authored over 150 peer-reviewed papers and secured $60M+ in research funding. Awards include the Bartimaeus Award for contributions to the blind community and multiple innovation awards. He leads IEEE's Engineering in Medicine and Biology Society committees and holds senior IEEE membership. Current projects focus on facial nerve paralysis treatments, high-density micro-electrode arrays, and improving cochlear implant efficacy. His lab collaborates with clinical partners to advance biocompatible neural interfaces and prosthetic systems.

Charles Burantمشاهده پروفایل

استاد

• Obesity
• Type 2 Diabetes
• Insulin Resistance
• +۵ مورد دیگر

Charles Burant is Professor of Nutritional Sciences at the University of Michigan School of Public Health and holds a professorship in the Section of Metabolism, Endocrinology, and Diabetes within the Medical School's Department of Internal Medicine. He holds the endowed Dr. Robert C. and Veronica Atkins Professor of Metabolism chair. His clinical practice focuses on obesity, type 2 diabetes, and related metabolic disorders at the WK Kellogg Eye Center, Brehm Tower in Ann Arbor. Dr. Burant's research integrates multi-omic approaches (genomics, transcriptomics, proteomics, metabolomics) with clinical and behavioral phenotypes to unravel mechanisms of obesity, insulin resistance, and diabetes. His laboratory investigates pancreatic beta-cell metabolism, insulin secretion dynamics, and adult pancreatic progenitor cells for beta-cell regeneration. As director of the Michigan Metabolomics and Obesity Center (MMOC), he oversees the NIH-funded Nutrition Obesity Research Center and Michigan Regional Comprehensive Metabolomics Resource Core, providing critical infrastructure for metabolic disease research. The MMOC also coordinates the Investigational Weight Management Clinic, which combines clinical care with phenotypic tracking to study diabetes prevention and weight regain mechanisms in formerly obese patients. Analysis of his recent publications reveals dominant themes in multi-omic exercise physiology, causal metabolite-disease relationships, and tissue-specific metabolic adaptations. His work consistently emphasizes sexual dimorphism, temporal dynamics, and molecular mechanisms in metabolic disorders, particularly through large-scale consortia like MoTrPAC. Key focus areas include lipid metabolism in disease contexts, adipose tissue remodeling, and mitochondrial function across tissues. While no specific scientific awards beyond his endowed chair are listed, his leadership of major NIH-funded centers demonstrates significant recognition. His grant portfolio includes infrastructure support through the MMOC, NORC, and Metabolomics Resource Core, enabling extensive human and animal studies in metabolic diseases. Dr. Burant directs the MMOC's integration of research and clinical care through the Investigational Weight Management Clinic. His laboratory maintains active programs in insulin resistance mechanisms using animal models and explores pancreatic progenitor cell applications for diabetes therapy, representing forward-looking approaches to metabolic disease treatment.

Tobias Moserمشاهده پروفایل

استاد

• Auditory Neuroscience
• Synaptic Physiology
• Audiology
• +۳ مورد دیگر

Prof. Dr. Tobias Moser is a Professor of Auditory Neuroscience and Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen. He leads the InnerEarLab and holds roles as spokesperson for the Multiscale BioImaging Cluster of Excellence (MBExC) and the Else Kröner Fresenius Center for Optogenetic Therapies. His work integrates molecular, physiological, and clinical approaches to auditory research. Education: MD from the University of Jena (1995), followed by postdoctoral work at the Max Planck Institute for Biophysical Chemistry. He has held leadership positions at multiple Max Planck Institutes and the German Primate Center (DPZ). Research Interests: Molecular anatomy and physiology of auditory synapses, synaptic pathophysiology, optogenetic therapies for hearing restoration, and gene replacement therapy. His group combines patch-clamp electrophysiology, super-resolution microscopy (e.g., 3D-MINFLUX), and biophysical modeling to study sound encoding and synaptic dysfunction. Recent Work Trends: Focus on hair cell ribbon synapse mechanisms, optogenetic cochlear implants, and the molecular basis of auditory synaptopathy. Collaborations include the Stefan Hell lab for nanoscale imaging and Fred Wolf’s theoretical neurophysics group. Grants & Labs: Funded by DFG (SFB 889/1690), Max Planck Society, and EU initiatives. Affiliated with labs at DPZ and the MPI for Multidisciplinary Sciences. Active in training through IMPRS programs in Neurosciences and Molecular Medicine.

• Brain Plasticity
• Neuronal Excitability
• Alzheimer's Disease
• +۷ مورد دیگر

Claudio Grassi is a Full Professor of Physiology at the Catholic University of the Sacred Heart, Faculty of Medicine and Surgery "A. Gemelli", Rome. He serves as Director of the Department of Neuroscience since 2019 and contributes to university governance as a member of the Quality Committee and Advisory Board. Graduate in Medicine and Surgery Specialist in Neurology PhD in Neuroscience His research focuses on: Mechanisms of brain plasticity and neuronal excitability Neurodegenerative disease biomarkers (Alzheimer's) Role of viral infections in neurodegeneration Noninvasive brain stimulation effects Metabolic influences on synaptic plasticity Cochlear damage and auditory cortex plasticity Recent publications analyze HSV-1 infection, tau propagation, and metabolic impacts on hippocampal function. Grassi mentors 10 PhD students and a Master's tutor. Contact: claudio.grassi@unicatt.it

Maoli Duanمشاهده پروفایل

دانشیار

• Otolaryngology
• Gene Therapy
• Stem Cell Therapy
• +۳ مورد دیگر

Maoli Duan is an Associate Professor and Senior Consultant at the Karolinska Institutet , affiliated with the Department of Clinical Science, Intervention and Technology under the Ear, Nose and Throat Diseases division. With over 150 peer-reviewed publications, his translational research bridges animal models and clinical applications in otolaryngology. Academic Rank: Associate Professor (Karolinska Institutet, 2006) Doctoral Degree: Department of Physiology and Pharmacology, Karolinska Institutet (1999) Research Focus Dr. Duan's work centers on gene therapy and stem cell treatments for sensorineural hearing loss , with recent breakthroughs in AAV vector delivery for congenital deafness. His 2025 Nature Medicine study demonstrated hearing restoration in patients with OTOF gene mutations through viral gene replacement. Publication Trends His 15 most recent articles (2023-2025) span biomedical engineering , clinical otology , and translational neuroscience . Key subfields include inner ear drug delivery , cochlear implants , gene therapy protocols , and viral vector optimization . Notably, his team has pioneered non-invasive approaches to treating Meniere's disease and noise-induced hearing loss . Collaborative Networks Dr. Duan collaborates with institutions across Europe , Asia , and North America , with recurring co-authors from Karolinska Institutet , University of Gothenburg , and Shanghai Jiao Tong University . His work appears in Nature Medicine , PNAS , and Advanced Science . Scientific Context Dr. Duan's research aligns with global efforts to address genetic hearing disorders through molecular interventions. His team's clinical trials demonstrate that gene therapy can restore near-normal hearing in OTOF mutation carriers without major adverse events, opening new pathways for non-invasive auditory restoration in both pediatric and adult populations.

John V. Brigandeمشاهده پروفایل

دانشیار

• Neuroscience
• Developmental Biology
• Auditory Development
• +۴ مورد دیگر

John V. Brigande is an Associate Professor at the Oregon Hearing Research Center, Oregon Health & Science University. He began his academic career at Boston College where he earned his B.S. (1987), M.S. (1991), and Ph.D. (1997) in neuroscience and developmental neurobiology. His postdoctoral training included developmental genetics at the University of Texas at Austin (1998) and auditory development at Purdue University (2003). He joined the Oregon Hearing Research Center as an Assistant Professor in 2003 and was promoted to Associate Professor in 2009. Since 2011, he has been a key contributor to the Hearing Health Foundation's Hearing Restoration Project. Education: B.S., Boston College, 1987 M.S., Boston College, 1991 Ph.D., Boston College, 1997 Postdoctoral Fellowship, University of Texas at Austin, 1998 Postdoctoral Fellowship, Purdue University, 2003 Brigande's research focuses on mammalian inner ear development , employing experimental embryology, surgical techniques, and gene transfer methods to study developmental processes in vivo. His lab investigates cell fate decisions in otic progenitors using retroviral lineage analysis and develops fetal gene/drug therapies for congenital deafness. A major focus is translating developmental mechanisms into gene and cell therapies for hearing loss and balance disorders, with particular emphasis on hair cell regeneration strategies. His publications demonstrate a strong focus on translational approaches to hearing restoration , including gene therapy (CRISPR/Cas9, AAV vectors), antisense oligonucleotides for congenital disorders, and optimization of diagnostic techniques. Recent work explores primate models of Usher syndrome, fetal pharmacotherapy, and mitochondrial genetics, reflecting interdisciplinary collaboration across genetics, audiology, and developmental biology. Brigande leads a research laboratory within the Hearing Health Foundation's Hearing Restoration Project consortium, focused on developing mouse model systems to validate hair cell regeneration candidates. The lab utilizes techniques including transuterine microinjection, in vivo electroporation, and single-cell transcriptomics to advance therapeutic strategies for inner ear disorders.

• Biomedical Engineering
• Cardiac Electrophysiology
• Neural Interfaces
• +۵ مورد دیگر

Overview Amr Al Abed is a Senior Lecturer at the Graduate School of Biomedical Engineering, University of New South Wales . He specializes in computational modeling, biomedical instrumentation, and electrophysiology with a focus on cardiac and neural systems. His work bridges biocomputational simulations with experimental validation, emphasizing translational applications like gene therapy delivery, medical devices, and brain-machine interfaces. Education PhD in Biomedical Engineering (UNSW, 2012) Masters in Biomedical Engineering (UNSW, 2006) Bachelor of Medical Sciences (1st Class Honours, UNSW, 2004) Research Interests His research spans: Optrode Technology: Development of liquid crystal-based optrodes for neural and cardiac sensing. Gene Electrotransfer: Novel methods for targeted DNA/RNA delivery using conductivity-clamped electric fields. Computational Cardiology: Multi-physics models of heart mechanics and fluid dynamics for surgical planning and device design. Neural Interfaces: Bidirectional stimulation/detection systems for retinal and neural prosthetics. Publications His 2023-2025 work highlights advancements in flexible electrode arrays , motorless robotic systems , and deep tissue gene delivery . Key themes include biomedical device innovation, computational modeling of cardiovascular systems, and neurotechnology. Grants & Labs Leads projects on liquid crystal optrodes and electrotransfer systems. Collaborates with labs focused on neural interfaces and cardiac electrophysiology. Active in IEEE and SPIE conferences with over 70 peer-reviewed publications.

• Otogenetic Research
• Gene and Regenerative Hearing Solutions
• Otology and Neurotology
• +۴ مورد دیگر

Nicolas Verhaert is a Professor at the Faculty of Medicine, KU Leuven, and head of the Experimental Otorhinolaryngology Research Group. He is actively affiliated with the KU Leuven Brain Institute (LBI) and Cancer Institute (LKI), and participates in the Faculty Council of Medicine and Departmental Council of Neurosciences. His research focuses on otogenetic studies, regenerative hearing solutions, and advanced hearing implants. His research interests span otology , neurotology , and hearing mechanics , with a specific emphasis on cochlear implants , bone conduction devices , and vestibular function . Recent publications highlight innovations in intraoperative trauma detection , vestibular implant stability , and genetic hearing loss . His work integrates biomedical engineering , neuroscience , and clinical otorhinolaryngology . Key trends in his publications include Development of in vivo biosensors for real-time inflammation monitoring Advancements in robot-assisted cochlear implantation Optimization of bone conduction electrode placement Longitudinal analysis of genetic speech perception deficits Systematic reviews on inner ear pharmacotherapy He supervises research projects involving students such as J. Wellens and E. Loos, and his team collaborates with institutions like the KU Leuven Brain Institute . The Experimental Otorhinolaryngology Research Group focuses on translational insights into cochlear mechanics, imaging, and biosensors.