جست‌وجوی استاد و پژوهشگر

Eduard Reznikمشاهده پروفایل

استادیار

• Cancer Metabolism
• Mitochondrial Genetics
• Cancer Genomics
• +۷ مورد دیگر

Eduard Reznik is an Assistant Professor at the Memorial Sloan Kettering Cancer Center , affiliated with the Gerstner Sloan Kettering Graduate School of Biomedical Sciences and the Epidemiology & Biostatistics department. His research focuses on cancer metabolism , mitochondrial genetics , and cancer genomics , with a translational emphasis on kidney cancer. Education : Summa Cum Laude Bachelor’s in Biological Engineering from Cornell University (2008); PhD in Biomedical Engineering from Boston University (2013). Postdoctoral Training : Memorial Sloan Kettering Cancer Center (2013-2017) under Christopher Sander and Niki Schultz. His lab employs machine learning , data science , and bioinformatics to study how genotype and tumor microenvironment interactions shape metabolic phenotypes. Recent projects include mitochondrial genetics , tumor metabolism , and cancer cachexia . Emerging trends from his 15 most recent articles (2020–2025) include metabolite imputation , pan-cancer biomarker discovery , and single-cell mtDNA dynamics . These span computational oncology , genomic instability , and immune-metabolite interactions . Current lab members include graduate students, postdoctoral fellows, and medical researchers working on multi-omics and translational cancer research . His work is supported by grants such as R01 CA258886 and U54 CA274492 .

• Bioinformatics
• Computational Biology
• Machine Learning
• +۳ مورد دیگر

Semih Kurt is a researcher at KTH Royal Institute of Technology, affiliated with the School of Electrical Engineering and Computer Science (EECS) and the Department of Computer Science's Computational Science and Technology (CST) division. He is also associated with Science for Life Laboratory (SciLifeLab), contributing to Sweden's national molecular biosciences infrastructure through computational genomics research. Education: PhD in Computer Science, KTH Royal Institute of Technology, 2024. Dissertation: "Methods for rapid phylogenetic inference and copy number variation detection from transcriptomics data". Research Interests: Kurt specializes in bioinformatics and computational biology , developing machine learning frameworks for genomic data analysis. His work addresses critical challenges in copy number variation (CNV) inference , phylogenetic reconstruction , and intratumoral heterogeneity using single-cell and spatial transcriptomics. By leveraging variational autoencoders and scalable algorithms , he creates tools that decode cancer progression mechanisms and evolutionary relationships with unprecedented resolution. Publication Trends: Kurt's 2022-2024 publications reveal a strategic focus on accelerating genomic analysis through algorithmic innovation. His CopyVAE and decoST frameworks demonstrate deep learning's power in CNV detection without prior biological knowledge, while Sparse Neighbor Joining reduces phylogenetic computation from quadratic to near-linear complexity. This trajectory shows consistent advancement in computational efficiency and biological interpretability , bridging computer science with cancer genomics and evolutionary biology. Scientific Awards: No scientific awards were mentioned in the provided text. Advising and Grants: The available documentation does not specify student supervision or research funding details. His collaborative work with Jens Lagergren (supervisor) and international co-authors suggests active participation in funded research consortia, though specific grants remain unreported. Labs and Teams: Kurt operates within KTH's Computational Science and Technology (CST) division, which develops computational methods for scientific challenges. His SciLifeLab affiliation connects him to Sweden's premier molecular biosciences hub, facilitating access to high-throughput sequencing facilities and cross-institutional cancer genomics initiatives.

Gloria Echeverriaمشاهده پروفایل

استادیار

• Triple Negative Breast Cancer
• Mitochondrial Biology
• Cancer Metabolism
• +۴ مورد دیگر

Gloria Echeverria, Ph.D., serves as an Assistant Professor in the Department of Molecular and Cellular Biology at Baylor College of Medicine. As Principal Investigator of the Echeverria Lab, she leads research focused on understanding the molecular evolution of triple negative breast cancer (TNBC), with particular emphasis on mitochondrial biology, metabolic adaptations, and mechanisms of therapy resistance. Her research program investigates how TNBC evolves and adapts during therapy resistance and metastasis, with a specialized focus on mitochondrial dynamics, metabolic reprogramming, and intra-organellar communication. The lab leverages state-of-the-art technologies in clinically relevant experimental models, particularly human patient-derived xenograft (PDX) models and human tumor cell lines, to discover critical mechanisms underlying resistance to cancer treatments. This work directly informs the development of mitochondria-targeting therapies with the ultimate goal of translating laboratory findings into clinical trials for TNBC patients. Analysis of Dr. Echeverria's recent publication record (2021-2025) reveals a consistent research trajectory centered on TNBC biology, with increasing sophistication in methodology. Her work has evolved from characterizing basic mechanisms of chemotherapy resistance and metastasis to developing advanced computational tools (like Xenomake) for spatial transcriptomic analysis and AI-based approaches for mitochondrial morphology assessment. A notable trend is the growing integration of multi-omics approaches with sophisticated preclinical models to deconvolute complex treatment responses in TNBC. Dr. Echeverria has demonstrated commitment to collaborative science through participation in multi-institutional research efforts and has pioneered frameworks for integrating patient advocates into cancer research. Her laboratory serves as a hub for translational breast cancer research, bridging fundamental biological discoveries with potential clinical applications specifically targeting the mitochondrial vulnerabilities of therapy-resistant TNBC.

Xiaolong Jiangمشاهده پروفایل

دانشیار

• Neuroscience
• Cortical Microcircuits
• Epilepsy
• +۴ مورد دیگر

Xiaolong Jiang is an Associate Professor at Baylor College of Medicine , jointly affiliated with the Department of Neuroscience and Department of Ophthalmology . His research focuses on cortical microcircuit organization in both healthy and pathological states, with particular emphasis on epilepsy and autism spectrum disorders . Expertise: Multi-cell patch recording (up to 12 simultaneous), single-cell RNA sequencing, optogenetics, machine learning Diseases Studied: Rett syndrome, Tuberous Sclerosis Complex (TSC), absence epilepsy, mesial temporal lobe epilepsy (mTLE) Key Techniques: Patch-seq, in vivo whole-cell recordings, two-photon calcium imaging, CRISPR genetic models Research spans cross-species comparisons (mouse, macaque) to uncover evolutionary principles of circuit organization. His work addresses how genetic lesions impact cortical circuit development and how aberrant circuitry (connectopathies) contributes to neuropsychiatric conditions. Current projects include deciphering primate prefrontal cortex microcircuits (NIMH R01 MH120404), TSC cortical tuber circuit mechanisms (DOD W81XWH-19-1-0079), and absence epilepsy circuit deficits (NINDS R01 NS102609-01A1).

Anita Lerchمشاهده پروفایل

عضو هیئت علمی

• Molecular Diagnostics
• Vector-Borne Diseases
• Genomics
• +۵ مورد دیگر

Anita Lerch is an Assistant Research Professor in the Department of Biological Sciences at the University of Notre Dame, where she has been a faculty member since 2023. She previously served as a Postdoctoral Research Associate in the same department from 2018 to 2023, demonstrating a sustained research trajectory within the institution. Ph.D. in Molecular Epidemiology, University of Basel, Switzerland (2018) M.S. in Computer Science, University of Basel, Switzerland (2008) B.S. in Computer Science, University of Basel, Switzerland (2006) Biological Laboratory Technician, Hoffmann - La Roche, Basel, Switzerland (1997) Her research focuses on the genomic and transcriptomic analysis of vector-borne pathogens, particularly Plasmodium and Trypanosoma . She investigates pathogen development within hosts and studies population dynamics of both pathogens and their vectors. Her work integrates advanced sequencing technologies and bioinformatics to understand infectious disease transmission and improve molecular diagnostics. The recent publications highlight a strong trend in infectious disease genomics, with emphasis on malaria ( Plasmodium falciparum and Plasmodium vivax ), deep sequencing applications, and computational modeling of vaccine impact. Her work bridges molecular biology, epidemiology, and data science, contributing to both method development and public health applications. Scientific Awards: No scientific awards explicitly mentioned in the provided text. Anita Lerch has been actively involved in research mentoring and collaborative projects, particularly in genomic surveillance and vaccine modeling. While no formal students are listed, her role as an Assistant Research Professor and postdoctoral researcher suggests involvement in training junior scientists. She has contributed to significant grants in infectious disease research, particularly in malaria genotyping and elimination strategies, though specific grant names are not detailed. She is affiliated with research teams focused on molecular diagnostics and vector-borne disease genomics at the University of Notre Dame, working within the Galvin Life Science Center. Her lab likely specializes in high-throughput sequencing data analysis, bioinformatics pipeline development, and collaborative infectious disease research.

Andreas Trumppمشاهده پروفایل

استاد

• Hematology
• Stem Cell Biology
• Cancer Progression
• +۳ مورد دیگر

Prof. Dr. Andreas Trumpp is a leading stem cell and cancer researcher at the German Cancer Research Center (DKFZ) and serves as the Managing Director of HI-STEM (Heidelberg Institute for Stem Cell Technology and Experimental Medicine). Since 2008, he has headed the Division of Stem Cells and Cancer, focusing on understanding the molecular mechanisms governing normal and malignant stem cells. His research spans Hematopoietic stem cell dormancy and activation Leukemia stem cell biology Metastasis mechanisms Ferroptosis and cancer metabolism Stem cell niche interactions Single-cell multi-omics in cancer progression Trumpp’s group has made significant contributions to understanding therapy resistance in acute myeloid leukemia (AML) and identified novel mechanisms for targeting cancer stem cells. His lab’s work on the SHATTER-AML project, funded by an ERC Advanced Grant (2022) , aims to develop precision therapies for cancers with structural genetic defects. Scientific accolades include being invited to deliver the Ham-Wasserman Lecture (2022) at the American Society of Hematology (ASH) meeting, a prestigious honor recognizing his global impact in hematology. His alumni include numerous successful researchers transitioning to positions at institutions like Max Planck Institute , TRON-Translational Oncology , and Novartis , reflecting his mentorship role in shaping the next generation of stem cell scientists.

• Genomics
• Structural Variation
• Cancer Biology
• +۳ مورد دیگر

Dr. Jan Korbel is a Senior Scientist and Group Leader at the European Molecular Biology Laboratory (EMBL) Heidelberg , with a joint appointment at EMBL-EBI . He serves as Interim Head of EMBL Heidelberg since April 2025 and leads the Data Science Centre since 2020. A faculty member of the ELLI Unit and an ERC Investigator since 2014, his research focuses on genomic structural variation , single-cell sequencing , and their roles in cancer and human evolution . PhD (2005): EMBL Heidelberg/Humboldt University Berlin Postdoctoral research: Yale University His work bridges computational biology and experimental genomics , with key contributions to long-read sequencing , haplotype-resolved assemblies , and pan-genome references . Recent articles demonstrate expertise in oncogenic structural variants , chromatin architecture , and global data-sharing frameworks like the Federated European Genome-Phenome Archive . Scientific awards : ERC Investigator status (2014) and leadership roles in major consortia (PCAWG, Human Genome Structural Variation Consortium). He developed tools such as MosaiCatcher , VISOR , and Alfred for structural variant analysis and alignment statistics.

• Leukemia Metabolism
• T-cell Acute Lymphoblastic Leukemia (T-ALL)
• Immunology
• +۳ مورد دیگر

Marissa Rashkovan is an Assistant Professor and Researcher at the University of Montreal's Faculty of Medicine, Department of Pathology and Cell Biology. Her work focuses on dissecting metabolic circuits in T-cell acute lymphoblastic leukemia (T-ALL), particularly the high-risk early T-cell precursor (ETP-ALL) subtype. Education: BSc in Biochemistry (2010) from McGill University, PhD in Experimental Medicine (2016) from IRCM/McGill University. Her research explores how leukemia cell metabolism differs from normal cells, identifying therapeutic targets through innovative tools and models. Key interests include cholesterol's role in leukemogenesis, oncogenic signaling, and epigenetic regulation. Recent studies highlight her team's work on inflammatory states in high-risk T-lineage ALL, metabolic dependencies in ETP-ALL, and enhancer hijacking mechanisms in stem cell leukemia. Her publications span top journals like Cancer Discovery and Science Translational Medicine . Scientific Awards: Damon Runyon Fellowships, ISEH New Investigator Award, AACR Women in Cancer Research Scholar Award, and multiple travel/graduate excellence awards. She leads the Rashkovan Lab at CHU Sainte-Justine Azrieli Research Center, using primary patient samples, xenografts, and mouse models to advance leukemia therapy development.

Michael Montgomeryمشاهده پروفایل

مدرس

• Media and Technology Convergence
• Corporate Finance
• Entrepreneurship
• +۲ مورد دیگر

Michael Montgomery is a Lecturer at the Anderson School of Business at UCLA, focusing on media-technology convergence and executive strategy. His career spans finance, media, and technology sectors, with expertise in M&A, equity financing, and corporate restructuring. Co-Founder & President of Montgomery & Co., LLC (1999-2013) Former CEO of Sega GameWorks and Senior Executive at DreamWorks SKG Leadership roles at Walt Disney Company and Arco Solar Board Director at DreamWorks Animation, Synacor, Open Methods, and M3Bio Education : MBA, Amos Tuck School at Dartmouth College (1977) BA (magna cum laude), Rufus Choate Scholar Research Focus : While his academic role emphasizes business strategy, recent Google Scholar publications indicate interdisciplinary engagement with: Genomic analysis of rare variants and structural variation Transcriptomic profiling in aging and disease Exercise physiology and multi-omic adaptation Advanced DNA/RNA sequencing technologies and diagnostics Scientific Awards : No explicit awards mentioned in the text. Advising & Boards : Served as board member/director for multiple public and private companies, with leadership roles in audit committees and strategic initiatives.

Adrian Baez-Ortegaمشاهده پروفایل

پژوهشگر ارشد

• Transmissible cancer
• Somatic evolution
• Cancer genome evolution
• +۳ مورد دیگر

Dr. Adrian Baez-Ortega is a computational biologist and Royal Society University Research Fellow based in the Departments of Zoology and Genetics at the University of Cambridge. His research focuses on transmissible cancers in animals, particularly marine bivalves, and he leads the Bivalve Transmissible Neoplasia Group with funding from the Royal Society and the European Research Council. Education: Undergraduate and postgraduate degrees in Computer Science, University of La Laguna (Spain) PhD in Biological Sciences, University of Cambridge Adrian’s research spans transmissible cancer , somatic evolution , and comparative genomics , with significant contributions to understanding cancer dynamics in bivalves and Tasmanian devils. His work has been featured in Nature Cancer and major media outlets like The New York Times . His recent genomic studies on transmissible cancers in marine cockles involved international collaborations and fieldwork across 11 countries. Adrian also develops computational tools, including the sigfit Bayesian mutational signature model, and contributes to scientific outreach through workshops and public engagement. Scientific Awards: Harold M Weintraub Graduate Student Award Science & SciLifeLab Prize for Young Scientists Adrian holds a Senior Research Fellowship at Magdalene College, Cambridge, and his interdisciplinary approach bridges bioinformatics, cancer biology, and evolutionary genetics. He actively mentors early-career researchers and supervises PhD students.

Fritz Sedlazeckمشاهده پروفایل

دانشیار

• Genomics
• Structural Variation Analysis
• Long-Read Sequencing
• +۳ مورد دیگر

Fritz Sedlazeck is an Associate Professor at the Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX. His research focuses on structural variation analysis, long-read sequencing, and bioinformatics, with applications in cancer genomics, neurogenetics, and pathogen characterization. He has developed computational tools like VACmap and DRAGEN for variant detection and alignment, and his work addresses challenges in tandem repeats, methylation patterns, and reference genome gaps. Research Interests: Structural variation in pediatric brain tumors and neurodevelopmental disorders Multiomics approaches to MECP2 Duplication Syndrome Technical innovations in long-read sequencing and variant calling Epigenetic regulation via DNA methylation Pathogen genomic characterization Recent Trends: His 2025 publications emphasize long-read sequencing for resolving complex genomic regions, benchmarking structural variants, and uncovering disease-relevant mutations. Key subfields include cancer genomics, neurogenetics, and computational methods for tandem repeats and methylation analysis. Affiliations: Baylor College of Medicine, Human Genome Sequencing Center.

Roslyn Tedjaمشاهده پروفایل

استادیار

• Ovarian Cancer
• Epithelial-Mesenchymal Transition (EMT)
• Intra-tumoral Heterogeneity
• +۳ مورد دیگر

Roslyn Tedja is an Assistant Professor in the Department of Obstetrics and Gynecology. Her research focuses on molecular mechanisms driving ovarian cancer progression, particularly epithelial-mesenchymal transition (EMT), intra-tumoral heterogeneity, and nanoparticle-based therapeutic strategies. Education: Ph.D. in Chemical Engineering, University of New South Wales, Sydney, Australia Research Interests Tedja's work spans: Molecular regulation of EMT in ovarian cancer Intra-tumoral heterogeneity in disease relapse Nanoparticle platform design for chemotherapy delivery Adipose microenvironment-cancer cell interactions Exosomal miRNA-mediated metastasis Recent Publications Her 2023–2024 studies highlight: Adipose microenvironment's role in hypersialylation (Front Oncol) MNRR1's impact on tumor progression (Transl Oncol) Exosomal miR-421 targeting CBX7 (J Ovarian Res) EMT hybrid cell generation (Cancers) Earlier work (2011–2012) addressed nanoparticle-cell interactions in non-cancerous contexts.

• Hematopathology
• Hematology
• Anatomic Pathology
• +۳ مورد دیگر

Diana Treaba is a Professor of Pathology and Laboratory Medicine at the Warren Alpert School of Medicine, Brown University. She serves as Director of Hematopathology and Hematology Laboratories for Lifespan Academic Medical Center, as well as Director of Brown's Pathology Residency Program. Her expertise spans Hematopathology, Hematology, Anatomic Pathology, and Clinical Pathology, with research focused on leukemia and lymphoma classification and pathobiology. MD: University of Medicine and Pharmacy, Targu-Mures (1993) Pathology Residency: Targu-Mures, Rush Presbyterian St. Luke's (Chicago) Fellowships: Hematopathology (Northwestern University), Immunohistochemistry (PhenoPath Labs, Seattle) Her research examines the molecular classification and pathobiology of hematologic malignancies, particularly leukemias and lymphomas. Key publications include studies on mutation analysis in mevalonate kinase deficiency, diagnostic challenges in plasma cell myeloma, and immunophenotypic heterogeneity in lymphomas. She has collaborated extensively with teams across hematology and oncology disciplines. Diana Treaba has received multiple teaching accolades at Brown University, including: Ronald A. De Lellis Teaching Award (2010) Excellence in Teaching Award (2013) Judith S. Heelan Teaching Award (2014)

Patricia T. Greippمشاهده پروفایل

پزشک-پژوهشگر

• Cytogenetics
• Multiple Myeloma
• Cancer Genomics
• +۳ مورد دیگر

Dr. Patricia T. Greipp is a physician scientist at the Mayo Clinic within the Department of Laboratory Medicine and Pathology and Mayo Clinic College of Medicine . With a career spanning over two decades, she specializes in clinical cytogenetics and genomic sequencing for hematologic malignancies. Doctor of Osteopathic Medicine (1997), Philadelphia College of Osteopathic Medicine Postdoctoral Fellowship in B12-targeted imaging/therapy (2008), Mayo Clinic Residency and Fellowship in Hematology/Oncology (2005), Mayo Clinic Her research focuses on multiple myeloma genomics , cancer cytogenetics , and molecular diagnostics for hematologic diseases. Recent publications highlight her contributions to therapeutic vulnerability screening and minimal residual disease (MRD) validation in myeloma. Dr. Greipp's work intersects genetic mutations (e.g., BCOR, ETNK1) and clinical outcomes in myeloid neoplasms. She leads the Cytogenetics Core Facility at Mayo Clinic and contributes to Cancer Genomics Consortium initiatives. 2025: Third Place Poster Award (Cancer Genomics Consortium) 2013: Best Poster Award (Association of Genetic Technologists) 2007 & 2006: Michael A. O'Connor Award for Young Investigators As a mentor and committee member, she guides hematopathology fellowship programs and participates in allogeneic transplant outcome analyses . Her leadership in CLIA-certified diagnostics ensures compliance with the College of American Pathologists.

Ann M. Moyerمشاهده پروفایل

دانشیار

• Pharmacogenomics
• Molecular Genetics
• Pathology
• +۵ مورد دیگر

Dr. Ann M. Moyer is an Associate Professor of Laboratory Medicine and Pathology and Assistant Professor of Pharmacology at Mayo Clinic College of Medicine and Science in Rochester, Minnesota. Board certified in molecular genetic pathology, anatomic pathology, and clinical pathology, she has established herself as a leading expert in pharmacogenomics and molecular diagnostics. Dr. Moyer earned her bachelor's degrees in Biology and Chemistry summa cum laude from the University of Wisconsin-Platteville before completing her MD/PhD through the Mayo Clinic Medical Scientist Training Program, where her thesis focused on pharmacogenomics of phase II drug metabolizing enzymes. She completed residency training in Anatomic and Clinical Pathology followed by a fellowship in Molecular Genetic Pathology at Mayo Clinic. Her research interests span pharmacogenomics, complement/immune system genetics, renal genetics, genetic testing for inborn errors of immunity, inherited renal disorders, and the genetics of Complement-Mediated Thrombotic Microangiopathy. Her publication record demonstrates significant contributions to clinical guidelines and implementation of pharmacogenomic testing. Dr. Moyer has received numerous awards including the 2024 Lifetime Achievement Award from the College of American Pathologists, 2024 Innovation & Leadership in Education Award from the Department of Laboratory Medicine and Pathology, and the 2022 Teacher of the Year in Clinical Pathology from the Mayo Clinic Fellows Association. She actively contributes to professional organizations serving on the College of American Pathologists Economic Affairs Committee, Council on Scientific Affairs, and as Co-Chair of the Department of Laboratory Medicine and Pathology Grand Rounds Planning Committee. Dr. Moyer also serves as Associate Director of the Pathology Residency Program and is involved with multiple pharmacogenomics implementation initiatives at Mayo Clinic.