جست‌وجوی استاد و پژوهشگر

• Mechanotransduction
• Cell Biology
• Nanobiotechnology
• +۴ مورد دیگر

Carsten Schulte is a Lecturer in Biomedical Engineering at the University of Strathclyde, with an active research career spanning over two decades. His work bridges engineering principles with cellular biology, focusing on how physical forces and topographical features influence cellular behavior and function. Dr. Schulte's research interests center on mechanotransduction, the process by which cells convert mechanical stimuli into biochemical signals. His work explores how nanoscale topographical features influence cellular adhesion, differentiation, and signaling pathways across various cell types including neurons, pancreatic beta cells, and cancer cells. He has made significant contributions to understanding the role of the glycocalyx, extracellular matrix, and cytoskeletal elements in mediating mechanotransductive responses. His publication record shows consistent output in high-impact journals including Nanoscale, Frontiers in Cellular Neuroscience, and Journal of Nanobiotechnology, with research trends indicating growing interest in patient-specific applications of mechanobiology principles, particularly in cancer research and regenerative medicine. Two prestigious scientific prizes recognizing contributions to nanobiotechnology and cell mechanics Extensive collaborative network across European institutions Research featured in multiple news outlets and cited in patents Dr. Schulte's work has practical applications in tissue engineering, biosensor development, and understanding disease mechanisms where mechanical forces play a critical role. His research group employs advanced techniques including atomic force microscopy, nanofabrication, and force spectroscopy to investigate cell-microenvironment interactions at the nanoscale level.

Jonas Paulsenمشاهده پروفایل

استاد

• 3D Genome Organization
• Computational Genomics
• Bioinformatics
• +۵ مورد دیگر

Jonas Paulsen is a Professor in the Department of Biosciences at the University of Oslo, Faculty of Mathematics and Natural Sciences. He leads the Paulsen group, established in early 2020, which is affiliated with the Centre for Bioinformatics and the Section for Genetics and Evolutionary Biology. His research focuses on the three-dimensional organization of DNA within the cell nucleus and its relationship to critical cellular functions including epigenetic regulation of gene expression. Paulsen's research interests center on computational 3D genomics, with an emphasis on understanding how nuclear architecture relates to cellular functions. His work involves developing computational tools and bioinformatics software to explore comparative 3D genomics across cell types, tissues, and species. The Paulsen group utilizes the Hi-C technique as a central technology, building computational tools to analyze these and related data to increase understanding of eukaryotic genome organization. Key projects include Chrom3D (a genome 3D modeling platform), statistical models of genome contact frequency maps, and research on genome domains and their functional and evolutionary basis. His publication record shows consistent output in top computational biology and genomics journals, with a clear trend toward increasingly sophisticated modeling of 3D genome organization. His work spans multiple subfields including chromatin architecture, computational modeling, bioinformatics tool development, epigenetics, and the relationship between genome architecture and disease processes like cancer. The research demonstrates strong interdisciplinary collaboration, particularly with Philippe Collas and other computational biologists. Paulsen teaches Bioinformatics (BIOS3010) and Bioinformatics for Molecular Biology (MBV-INF4410), continuing his commitment to training the next generation of computational biologists. His group's work has significant implications for understanding fundamental biological processes and disease mechanisms through the lens of spatial genome organization.

Mohsin Badatمشاهده پروفایل

مدرس ارشد

• Inherited Bone Marrow Failure Syndromes
• Telomere Biology
• Genomics
• +۴ مورد دیگر

Dr. Mohsin Badat is a Senior Clinical Lecturer and Honorary Consultant in Paediatric Haematology at the Blizard Institute , part of Queen Mary University of London. He works within the Centre for Genomics and Child Health , focusing on inherited bone marrow failure syndromes and telomere biology disorders. MB BChir, University of Cambridge DPhil, University of Oxford MRCPCH, FRCPath His research explores the genomic causes and molecular mechanisms of rare haematopoietic disorders, particularly Telomere Biology Disorders, aiming to develop novel therapies for β-thalassemia and related conditions. Recent publications highlight his work in genomics , haematology , and genome engineering , with a focus on base editing, enhancer function, and clinical translation. Royal College of Pathologists Gold Research Medal 2024 He leads the Telomere Biology Disorder Lab and collaborates on clinical referrals for bone marrow failure patients through the NHS.

• Statistical Physics
• Soft Matter Physics
• Colloidal Systems
• +۳ مورد دیگر

Giorgio Cinacchi is an Associate Professor at the Autonomous University of Madrid (UAM), holding a Ramón y Cajal research fellowship since 2011. His work focuses on the Statistical Physics of Complex Liquids and Biophysics within the university's research institute, with office location in Module 5, 5th floor. Education: PhD from Scuola Normale Superiore (SNS) di Pisa (2004) Undergraduate and postgraduate scholarships at Scuola Normale Superiore di Pisa His research centers on statistical mechanics of soft matter , employing theoretical and numerical simulation approaches to investigate phase behavior in colloidal systems with non-convex shapes (lens-, bowl-like, and helical particles) and in silico design of semi-conductive discotic liquid crystals . This work bridges fundamental entropy-driven phenomena with materials science applications, particularly in anisotropic fluid systems. Analysis of his 10 publications (2002-2014) reveals consistent focus on phase transitions in anisotropic particle systems , with evolving emphasis from hard-spherocylinder mixtures (2004) to complex nematic phases (2014). Key methodologies include density functional theory and molecular dynamics, targeting applications in liquid crystal technology and biophysical systems. Awards and Honors: Ramon y Cajal research fellowship (2011-present) Marie Curie individual research fellowship at University of Bristol (2008-2010) Vincenzo Caglioti Prize from Accademia dei Lincei, Rome (2008) Dr. Cinacchi's research has been sustained through competitive European and national fellowships. While specific student mentorship isn't documented, his active publication record suggests involvement in graduate training. His work demonstrates strong theoretical foundations with emerging applications in electronic materials design. He operates within UAM's IFIMAC (Institute for Theoretical and Computational Modeling of Condensed Matter), leading research in complex liquid systems through computational modeling and theoretical frameworks that connect molecular structure to macroscopic phase behavior.

Leah A. Gatesمشاهده پروفایل

استادیار

• Metabolism-Chromatin Interactions
• Epigenetic Regulation
• Intestinal Biology
• +۴ مورد دیگر

Leah A. Gates, PhD is an Assistant Professor in the Department of Biochemistry at Case Western Reserve University School of Medicine and a Member of the Cancer Genomics and Epigenomics Program at the Case Comprehensive Cancer Center. Her research program investigates the intersection between metabolism, chromatin, and gene regulation with a particular focus on the intestine as a model system. Dr. Gates earned her PhD in Molecular Biology from Baylor College of Medicine in 2017 and completed her postdoctoral training at The Rockefeller University. Her laboratory employs biochemical techniques, cell culture, organoid systems, and animal models to investigate how metabolite signaling to chromatin impacts cell and tissue function in health and disease. Dr. Gates' research focuses on three primary areas: mechanisms of metabolite signaling to chromatin, the role of chromatin in intestinal cell fate determination, and metabolism-chromatin interactions in disease. Her work particularly examines how environmental cues such as diet and microbiota regulate the chromatin landscape and gene expression programs, with special interest in histone butyrylation. She investigates how chromatin regulates intestinal cell fate across different epithelial cell types that have distinct metabolic profiles depending on their location in the epithelium. Analysis of Dr. Gates' publication record reveals a strong focus on the molecular mechanisms linking cellular metabolism to chromatin modifications and gene regulation. Her recent work demonstrates how microbiota-derived metabolites regulate histone modifications in the intestine, establishing direct connections between environmental factors, epigenetic regulation, and tissue function. Her research bridges basic biochemical mechanisms with physiological relevance in intestinal biology and cancer. Dr. Gates has established herself as a leading researcher in the emerging field of metabolite-chromatin signaling, with publications in high-impact journals including Nature Metabolism, Nature, Cell Metabolism, and Cell Reports. Her work has been particularly influential in demonstrating how short-chain fatty acids from the microbiota regulate histone modifications in the mammalian intestine. As principal investigator of the Gates Lab, she leads research investigating how the chromatin landscape integrates diverse cellular signals to regulate genome structure and biological functions through post-translational modifications on histone proteins. Her laboratory continues to explore how alterations in metabolism change cellular responses to environmental cues and impact tumorigenesis, with particular interest in how cancer-associated mutations in chromatin modifying enzymes alter the intersection between metabolism and chromatin.

• Epigenetics
• Chromatin Biology
• Cellular Identity and Differentiation
• +۳ مورد دیگر

M. Andres Blanco is an Assistant Professor at the Department of Biomedical Sciences , University of Pennsylvania School of Veterinary Medicine . He is also affiliated with the Institute for Regenerative Medicine and the Abramson Cancer Center , both at the Perelman School of Medicine. His research focuses on epigenetics, chromatin biology, and cellular identity, particularly in the context of cancer progression and metastasis. Epigenetics Chromatin Biology Cellular Identity and Differentiation Cancer Epigenetics Transcriptional Regulation in Cancer Metastasis Mechanisms Blanco’s recent work explores the interplay between epigenetic regulation and cellular differentiation in cancers such as AML and pancreatic cancer . His research highlights the role of chromatin-state barriers in irreversible cell fate decisions, and the impact of LSD1 and WNT pathway perturbations on AML differentiation . He has also contributed to understanding how epigenetic and metabolic treatments can overcome differentiation blockades in leukemia . His publications span topics like histone modifications , nucleosome mapping , and epigenetic marks such as N6-adenine DNA methylation in C. elegans . He has collaborated with researchers across institutions like Harvard Medical School and Boston Children’s Hospital, and has contributed to studies involving epigenetic inhibitors for cancer treatment. Blanco received his PhD in Molecular Biology from Princeton University (2011) and a BA in Biological Sciences and Philosophy from Cornell University (2004)

• Neuroscience
• Molecular Biology
• Cell Biology
• +۴ مورد دیگر

Italia Di Liegro serves as a Contract Teacher in the Department of Biomedicine, Neuroscience and Advanced Diagnostics at the School of Medicine and Surgery, University of Palermo. She maintains regular office hours at multiple locations including Palermo's Viale delle Scienze campus (Building 16/STEBICEF) and CEFPAS in Caltanissetta, demonstrating her commitment to student accessibility across different sites. Dr. Di Liegro's research spans several decades with a consistent focus on cellular and molecular neuroscience. Her early work centered on thyroid hormones and chromatin structure in brain development, while her more recent research has evolved to investigate extracellular vesicles as critical mediators of cell-to-cell communication in the nervous system. She has made significant contributions to understanding how astrocytes contribute to blood-brain barrier function and how extracellular vesicles facilitate information exchange between brain cells in both physiological and pathological conditions. Analysis of her publication history reveals a clear research trajectory moving from fundamental molecular mechanisms to translational applications. Her recent work (2020-2024) prominently features studies on extracellular vesicles in brain tumor progression, epigenetic regulation of neural function, and development of therapeutic approaches for neurological disorders. She has developed innovative in vitro models using poly-L-lactic acid scaffolds to study astrocyte behavior and glioma development, bridging basic science with potential clinical applications. Dr. Di Liegro has supervised numerous graduate theses and mentored students in neuroscience research, though specific student names are not listed in the available materials. Her multidisciplinary approach connects molecular mechanisms with clinical applications, particularly in developing training programs for Parkinson's disease and multiple sclerosis patients. Her laboratory work primarily focuses on in vitro models of brain cells, with extensive characterization of astrocyte behavior, blood-brain barrier models, and glioma cell lines. She has pioneered methods for studying cell migration and differentiation using specialized 3D culture systems, contributing significantly to our understanding of brain development, neurological disorders, and cancer progression.

Adam N. Goldfarbمشاهده پروفایل

استاد

• Hematopathology
• Molecular Biology
• Hematopoiesis
• +۸ مورد دیگر

Dr. Adam N. Goldfarb is a Professor of Pathology and Chief of the Division of Experimental Pathology at the University of Virginia School of Medicine . His clinical expertise lies in hematopathology , focusing on morphologic and immunophenotypic classification of bone marrow and lymph node disorders. Education : MD from Tufts University School of Medicine (1986); residency in anatomic and clinical pathology at University of Minnesota Hospital (1986-1993); fellowship in hematopathology at University of Minnesota Hospital (1988-1989). Dr. Goldfarb's research investigates the molecular basis of hematopoiesis and leukemogenesis . His lab analyzes the SCL/tal transcription factor , which governs hematopoietic stem cell development and contributes to T-cell acute lymphoblastic leukemia. He also studies signaling pathways in megakaryocyte development , employing techniques such as site-directed mutagenesis, protein interaction assays, and computational modeling to dissect transcriptional complexes. Recent publications highlight his work on PU.1 regulation in blood lineages (2024), DYRK1A repression in megakaryocytes (2022), and chromatin structure in hematopoietic gene expression (2024). His studies often bridge fundamental molecular mechanisms with translational applications in hematologic malignancies.

• Biochemistry
• Structural Biology
• Structural Immunology
• +۴ مورد دیگر

Massimo Degano is a Lecturer at San Raffaele Vita-Salute University , with a career spanning structural biology, biochemistry, and translational medicine. His work focuses on macromolecular structural characterization using X-ray crystallography and biophysical techniques, particularly in immunology and drug design. Education: Chemistry (1992) Key affiliations: Fondazione San Raffaele, Elettra-Sincrotrone Trieste, The Scripps Research Institute Research interests include: Structural Immunology – Investigating B-cell receptor dynamics in lymphoid malignancies (CLL, splenic marginal zone lymphoma) and antigen recognition mechanisms. Structure-Based Drug Design – Developing therapeutic strategies against cancers and infectious diseases through molecular modeling. Macromolecular Complexes – Analyzing protein interactions in immunoglobulins, proteases, and ribosomal components. Translational Medicine – Bridging structural insights to clinical gene therapy applications (e.g., mucopolysaccharidosis IVB). Recent publications (2025-2020) highlight structural studies on: ERC1/ELKS condensates in cell motility Somatic hypermutation in SARS-CoV-2 immune responses ClpP protease inhibition in multiple myeloma GPR17 receptor for remyelination therapy Scientific engagements include membership in the Società Italiana di Immunologia e Allergologia Clinica (2021-present) and editorial service at Frontiers in Molecular Biosciences (2020-present). His work emphasizes interdisciplinary collaboration and external grant funding for structural biology projects.

Enrique M. Muroمشاهده پروفایل

استاد

• Computational Biology
• Genome and Proteome Evolution
• Genomics
• +۱۱ مورد دیگر

Enrique M. Muro is a tenured Principal Investigator and Professor at the Institute of Organismic and Molecular Evolution (iomE) within the Faculty of Biology at Johannes Gutenberg University of Mainz , Germany. His interdisciplinary work bridges computational biology, bioinformatics, and evolutionary theory with applications in genomics and systems biology. Fields of Interest: Computational Biology, Genome and Proteome Evolution, Genomics, Non-coding Genes, Pseudogenes, Transcriptional Regulation, Mobile DNA, Systems Biology, Three-dimensional Chromatin Structure, Artificial Intelligence, Neural Networks, and Models for Central Visual System Development. Key Research: Quantitative analysis of eukaryogenesis as a phase transition, evolutionary implications of protein coding gene length distributions, and functional studies of pseudogenes and retrotransposons. Teaching: Offers courses in Python programming for biologists, biostatistics, and bioinformatics at undergraduate and graduate levels since 2014. Authored an open-access online book Fundamentals of programming in biomedicine with Python . Supervision: Mentors Master’s students Anna Christina du Plessis (DAAD scholarship, 2024) and Emilia Körner (2025), and supervised Sweta Talyan (PhD, 2018). Outreach: Authored the book Bioinformatics: Entre la carne y la máquina , translated into Italian and Romanian, and actively disseminates computational biology education.

Jing Wangمشاهده پروفایل

عضو هیئت علمی

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۳ مورد دیگر

Jing Wang is a Research Assistant Professor at the Department of Biostatistics , Vanderbilt University , with a focus on integrating bioinformatics and biostatistical methods to study cancer genomics, RNA biology, and chromatin dynamics. Education: PhD in Bioinformatics from Shanghai Jiao Tong University Research interests center on: Transcriptional regulation in oncogenic pathways Non-coding RNA interactions in cancer metastasis Epigenetic mechanisms in tumor development Computational modeling of gene expression programs RNA sequencing data analysis Chromatin remodeling in SMARCB1-deficient cancers Recent work emphasizes: WDR5 inhibition strategies for hematologic malignancies MYC-driven gene regulatory networks Super-enhancer dynamics in rhabdoid tumors miRNA and lncRNA roles in colorectal cancer progression Adapter detection tools for small RNA sequencing Evolution of transcriptional programs under epigenetic regulation

Anaïs Noblancمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Cell Biology
• Reproductive Biology
• +۳ مورد دیگر

Anaïs Noblanc is a Researcher at the University of Poitiers, affiliated with the PRODICET Laboratory within the Biology and Health Center. Her work focuses on molecular and cell biology, particularly investigating oxidative stress mechanisms in male reproductive systems. She specializes in sperm chromatin integrity, antioxidant systems, and the physiological processes governing fertility. Her research interests include understanding how aging and oxidative damage affect sperm nuclear structure, as well as identifying protective roles of tissues like the epididymis and meibomian glands. She utilizes mouse models and in vitro systems to explore these mechanisms, contributing to advancements in male infertility treatments and antioxidant formulations. Key research trends in her publications emphasize the interplay between oxidative stress, DNA damage, and reproductive outcomes. Her work highlights compensatory mechanisms in post-testicular environments and the critical role of enzymes such as glutathione peroxidases. Collaborations with clinical partners are implied through her affiliations with university hospitals. Her current projects are centered on translational research linking basic biology to clinical applications, particularly in developing antioxidant therapies for male infertility. No specific grants or awards are listed, though her active publication record suggests sustained research engagement.

Charles Chenمشاهده پروفایل

استادیار

• Genomics
• Bioinformatics
• Plant Genetics
• +۳ مورد دیگر

Charles Chen is an Assistant Professor of Bioinformatics at Oklahoma State University (OSU), holding a dual affiliation with the Department of Biochemistry and Molecular Biology and the Institute for Biosecurity & Microbial Forensics (IBMF). His research office is located in Room 348G of the Noble Research Center in Stillwater, OK, where he conducts interdisciplinary work at the intersection of genomics, bioinformatics, and agricultural security. Dr. Chen's research program focuses on deciphering the genetic, environmental, and evolutionary mechanisms driving biological diversity, with particular emphasis on plant systems. His work spans: Genomic analysis of climate adaptation in conifers, wheat, and peanut Microbiome dynamics in agricultural biosecurity contexts Drought stress response mechanisms and breeding for climate resilience Development of computational frameworks for genomic prediction and breeding optimization Integration of UAV-based phenotyping with genomic data His recent publications (2023-2025) reveal a cohesive research trajectory centered on applying advanced genomic tools to solve pressing agricultural challenges. Key thematic areas include drought adaptation in forest trees and crops, genomic selection methodologies, and the fusion of computational biology with field-based phenomics. His work consistently bridges theoretical genomics with practical breeding applications, particularly in climate-vulnerable systems. Dr. Chen actively collaborates with the Oklahoma Wheat Commission and Oklahoma Wheat Research Foundation, as evidenced by his involvement in wheat microbiome projects. While specific advisees aren't listed in available materials, his research scope suggests mentorship of students in computational genomics and plant breeding. His work receives support from agricultural research initiatives focused on climate-resilient crop development. As a core member of OSU's Institute for Biosecurity & Microbial Forensics, he contributes bioinformatic expertise to agricultural security projects. His laboratory likely integrates high-performance computing with molecular biology approaches, maintaining collaborations across plant science, forestry, and computational disciplines to address food security challenges through genomic innovation.

Emma Morrisonمشاهده پروفایل

استادیار

• Chromatin Regulation
• Histone Dynamics
• Biophysical Techniques
• +۳ مورد دیگر

Dr. Emma Morrison is an Assistant Professor in the Department of Biochemistry at the Medical College of Wisconsin. She holds a PhD in Molecular Biophysics from Washington University in St. Louis and a BA in Chemistry from Johns Hopkins University. Her postdoctoral training at the University of Iowa focused on chromatin regulation, where she studied nucleosome structure and dynamics. Dr. Morrison’s research explores molecular mechanisms of chromatin regulation, particularly the role of histone tails in nucleosome function. She uses biophysical techniques like NMR spectroscopy to investigate histone tail conformation, accessibility, and interactions with regulatory machinery. Her work highlights how histone post-translational modifications (PTMs) and variants modulate nucleosome dynamics, impacting gene regulation and human health. Key findings include the reduced accessibility of histone tails within nucleosomes and the influence of histone tails on phase separation. Dr. Morrison has been awarded a Beckman Foundation fellowship for her postdoctoral research. Her lab develops protocols for nucleosome reconstitution and employs interdisciplinary approaches to advance chromatin biology. Major interests: Nucleosome structure, histone PTMs, chromatin accessibility, biophysical methods Techniques: NMR spectroscopy, molecular dynamics simulations Awards: Arnold and Mabel Beckman Foundation Fellowship (2014-2019) Lab focus: Quantitative analysis of histone tail dynamics in chromatin contexts. Collaborates on projects involving histone variants, epigenetic modifiers, and disease mechanisms.

Danica Galonić Fujimoriمشاهده پروفایل

استاد

• Chemical Biology
• Epigenetics
• RNA Methylation Mechanisms
• +۳ مورد دیگر

Dr. Danica Galonić Fujimori is a Professor in the Department of Cellular and Molecular Pharmacology at the University of California, San Francisco (UCSF). Her primary affiliation is with the UCSF School of Pharmacy, with joint appointments in the Department of Pharmaceutical Chemistry. She leads the Fujimori Lab, which focuses on developing chemical tools to study biological processes, particularly epigenetic regulation and antibiotic resistance mechanisms. Dr. Fujimori holds a PhD in Chemistry from the University of Illinois at Urbana-Champaign (2005) and a BSc in Chemistry from the University of Belgrade, Serbia (2000). Her research expertise includes nucleic acid synthesis, bioconjugation, tissue engineering, and cell-cell interactions. She investigates the molecular mechanisms of protein and RNA methylation, with a focus on histone demethylases (Jumonji family) and bacterial ribosomal RNA modifications. Her work aims to develop small molecule inhibitors for therapeutic applications in cancer and infectious diseases. Notable achievements include identifying ligands for histone demethylase domains and elucidating antibiotic resistance mechanisms in bacteria. Dr. Fujimori has received prestigious awards such as the WM Keck Medical Research Award (2020), Searle Scholar Award (2011), and NSF Career Award (2011). She is affiliated with the UCSF Helen Diller Family Comprehensive Cancer Center and the Quantitative Biosciences Institute (QBI). Her research integrates chemical biology, biochemistry, and structural biology to address fundamental biological questions and translational challenges.