جست‌وجوی استاد و پژوهشگر

Satyanarayana Andeمشاهده پروفایل

دانشیار

• Liver Cancer
• Cancer Metabolism
• Obesity-associated Liver Disease
• +۳ مورد دیگر

Satyanarayana Ande is an Associate Professor in the Department of Biochemistry and Molecular Biology at the Medical College of Georgia, Augusta University. He is a member of the Molecular Oncology and Biomarkers Program at the Georgia Cancer Center. His research focuses on liver cancer, cancer metabolism, and obesity-associated liver diseases. Dr. Ande earned his Ph.D. in Natural Sciences from Universität Hannover (2004), and holds an MS (Biotechnology, 1998) and BS (Biotechnology, 1996) from Nagarjuna University. Research Interests: His laboratory investigates novel cytokines and transcription factors in liver and adipose tissues, particularly their roles in hepatocellular carcinoma (HCC), metabolic adaptation of cancer cells, and obesity-induced non-alcoholic fatty liver disease (NAFLD). Techniques include RNAseq, Mass-Spec, and mouse models to study metabolic pathways and tumor suppression mechanisms. Recent work highlights NADP(P)H quinone dehydrogenase 1's role in HCC metabolic pathways and ZAG's promotion of adipose tissue browning. Service Contributions: Served on Augusta University's Faculty Rules and Responsibilities committee (2019–present), and contributed to the GCC-RIP Seminar Series (2019–2020). Courses taught include MEDI 6220 (Cardiopulmonary/Heme) and BIOM 8215 (Fundamentals of Oncology I). Laboratory: The Ande Lab is located at the Georgia Cancer Center's M. Bert Storey Research Building. Contact: sande@augusta.edu

Nilay Patelمشاهده پروفایل

دانشیار

• Drug Discovery
• Cell Cycle Regulation
• Signal Transduction
• +۳ مورد دیگر

Dr. Nilay Patel is an Associate Professor in the Department of Biological Science at California State University, Fullerton (CSUF). His research focuses on drug discovery, particularly the anti-proliferative effects of niclosamide and related compounds on cancer cells, with collaborations in chemistry and biochemistry. He investigates signal transduction pathways and gene expression regulation in cell cycle processes. Dr. Patel teaches courses in cellular/molecular biology, stem cell biology, and related advanced topics. Education: PhD, The State University of New York, Stony Brook BS, University of Cincinnati Research Interests: Design and testing of anti-cancer compounds targeting β-catenin reduction Impact of signal transduction pathways on cancer proliferation Collaborative drug development with CSUF Chemistry & Biochemistry Department Publications Trends: His work bridges pharmacology and cell biology, emphasizing stem cell pluripotency, neurodegenerative disease mechanisms, and aging-related biomarkers. Key themes include caloric restriction effects on amyloid accumulation and glial cell functions. Awards/Grants: Bridges to Stem Cell Research (BSCR) Program Advising & Mentorship: Supervised multiple student co-authors in stem cell and cancer biology research projects. Active in training through internships (BIOL 495C) and advanced seminars.

Leah Chase-Wallarمشاهده پروفایل

استاد

• Neuroscience
• Biochemistry
• Neurochemistry
• +۳ مورد دیگر

Dr. Leah Chase-Wallar serves as Professor of Biology & Chemistry at Hope College since 2000, maintaining active research in the A. Paul Schaap Science Center with dual departmental affiliations in Chemistry and Biology. Her work bridges neurochemistry and molecular biology through investigations of oxidative stress mechanisms in neurodegenerative disorders. She earned her B.S. from the University of Michigan – Flint (1993) followed by a Ph.D. from the University of Minnesota (1999), establishing her foundation in biochemical neuroscience. Her research program centers on system x c - regulation, specifically examining how hydrogen peroxide modulates cystine/glutamate exchange to protect dopaminergic neurons in Parkinson's disease models. This involves advanced techniques including mammalian cell culture, immunocytochemical analysis, western blotting, and enzymatic assays for glutathione/peroxide measurement. Her publication trajectory (1994-2007) reveals evolving specialization: early comparative physiology work on reindeer nutrition transitioned into focused neuroscience research on glutamate transport systems, metabotropic receptor pharmacology, and neurotoxin mechanisms. The most recent publications demonstrate increasing emphasis on oxidative stress pathways relevant to Parkinson's disease. Dr. Chase-Wallar has secured substantial research funding including multiple Campbell Foundation grants (2001-2007), a Towsley Research Scholar award (2003-2006), and NSF support (2002-2003) for neuroscience laboratory development. Her Chase-Wallar Research Group actively involves undergraduate students in project design and execution within Hope College's Chemistry Department framework, with facilities in the A. Paul Schaap Science Center enabling cellular and molecular investigations of dopaminergic systems.

Eduardo Maldonadoمشاهده پروفایل

دانشیار

• Mitochondrial Metabolism
• Cancer Bioenergetics
• Voltage-Dependent Anion Channels (VDAC)
• +۵ مورد دیگر

Eduardo Maldonado is an Associate Professor in the Drug Discovery and Biomedical Sciences department at the College of Pharmacy, Medical University of South Carolina (MUSC) . His research focuses on mitochondrial metabolism in cancer cells, T cells, and cancer stem cells, particularly targeting mechanisms regulating Voltage-Dependent Anion Channels (VDAC) to develop therapeutic strategies. Education: DVM from Universidad Nacional del Centro (1986), PhD in Human Pathophysiology from Universidad Nacional del Sur (2001), Postdoctoral training at MUSC (2006, 2010), Predoctoral research at University of the Basque Country (1999). Research Interests: Mitochondrial metabolism regulation in cancer, VDAC-targeted small molecules, T cell immunometabolism, and cancer stem cell biology. His lab (established in 2015) explores how modulating VDAC channels through tubulin interactions or NADH-binding pockets can alter tumor proliferation and survival. Article Trends: Recent publications highlight VDAC's role in cancer bioenergetics, immunometabolic reprogramming (e.g., H2S-Prdx4 axis), and synergistic drug combinations. Earlier works emphasize mitochondrial ROS, lipid metabolism, and Golgi stress in disease contexts. Labs & Teams: Leads a research group at MUSC's College of Pharmacy, affiliated with the Developmental Cancer Therapeutics Program at Hollings Cancer Center. His work bridges mitochondrial physiology, cancer metabolism, and pharmacological intervention.

Kimberly E. Beattyمشاهده پروفایل

استاد

• Chemical Biology
• Medical Research
• Proteomics
• +۳ مورد دیگر

Kimberly E. Beatty is a faculty member at Oregon Health & Science University (OHSU), affiliated with the School of Medicine. Her research focuses on developing innovative chemical tools and technologies to study human diseases, particularly tuberculosis (TB) and breast cancer. The Beatty group employs interdisciplinary and collaborative strategies to investigate molecular mechanisms underlying disease pathology, drug susceptibility, and resistance. Education: B.S. from University of California, Santa Barbara (2002) Ph.D. in Chemistry from California Institute of Technology (2008) under David Tirrell Postdoctoral training at UC Berkeley with Carolyn Bertozzi Her research projects include: chemical tools for Mtb hydrolase detection, drug susceptibility imaging, protein mapping via VIPER technology, breast cancer drug resistance mechanisms, and fluorescent probe synthesis. Publications span proteomics, molecular imaging, and biochemical diagnostics. She has mentored researchers such as Kaylyn L. Devlin and Julia K. Doh.

Rachel K. Roweمشاهده پروفایل

استادیار

• Neurotrauma
• Sleep Architecture
• Neuroinflammation
• +۲ مورد دیگر

Rachel K. Rowe is an Assistant Professor in Integrative Physiology at University of Colorado Boulder. Her research examines bidirectional relationships between sleep disturbances and neuroinflammation after traumatic brain injury (TBI), particularly in pediatric populations. Education includes PhD in Anatomy and Neurobiology from University of Kentucky (2014) and postdoctoral training at Barrow Neurological Institute. Research focuses on how injury timing (age-at-injury) affects long-term outcomes, mechanisms linking TBI to neurodegeneration, and microglial roles in sleep regulation post-injury. Her lab employs rodent models of TBI and advanced neuroimaging techniques. Awards include National Neurotrauma Society Rising Star Award (2022) and World Sleep Society Young Investigator Award (2019). She has received NIH funding for TBI-sleep research.

Max Stallerمشاهده پروفایل

استادیار

• Transcriptional Regulation
• Gene Expression
• Intrinsically Disordered Proteins
• +۳ مورد دیگر

Max Staller is an Assistant Professor in the Department of Molecular and Cell Biology at the University of California, Berkeley, affiliated with the College of Letters & Science and the Center for Computational Biology. His lab focuses on understanding how transcriptional activation domains regulate gene expression through interdisciplinary approaches combining experimental, computational, and theoretical methods. Research Interests: Transcriptional regulation mechanisms in development and stress responses Functional analysis of intrinsically disordered protein domains Machine learning applications in protein sequence-function prediction Evolutionary dynamics of transcription factors Grants & Collaborations: Lead investigator on the NSF-funded PlantSynBio project (2021) for identifying transcriptional activation domains across plant species. Collaborates with the Cohen Lab (Washington University) on mutational scanning studies. Labs & Affiliations: Director of the Staller Lab, which integrates high-throughput experiments with computational modeling. Active in the Berkeley Bioscience community and the Center for Computational Biology.

Ulrich G. Steidlمشاهده پروفایل

استاد

• hematopoiesis
• stem cell origin of cancer
• leukemia
• +۱۰ مورد دیگر

Ulrich G. Steidl, M.D., Ph.D., is a Professor in the Departments of Cell Biology, Oncology, and Medicine at Albert Einstein College of Medicine. He serves as Chair of the Department of Cell Biology and holds the Edward P. Evans Endowed Professorship for Myelodysplastic Syndromes. He is also Co-Director of the Blood Cancer Institute and Deputy Director/Associate Director for Basic Science at the Montefiore Einstein Comprehensive Cancer Center. His research focuses on understanding the molecular mechanisms driving the transformation of hematopoietic stem cells (HSC) into pre-leukemic and leukemia stem cells (LSC), with a particular emphasis on transcription dynamics, epigenetic regulation, and targeted therapy development. Key areas include investigating how transcriptional plasticity and signaling mediators contribute to leukemia progression, and developing strategies to intercept cancer at the pre-leukemic stage. Selected publications highlight breakthroughs in transcription factor activity modulation, glycan-based cell characterization, and MDMX-driven AML progression. His work advances translational computational biology and drug development for precision therapies targeting stem cell pathways. Steidl’s contributions span the Montefiore Einstein Comprehensive Cancer Center and Blood Cancer Institute, emphasizing collaborative efforts in basic science and clinical translation. His research addresses critical gaps in understanding therapy resistance and disease relapse mechanisms.

Irwin J. Kurlandمشاهده پروفایل

دانشیار

• Metabolic Flexibility
• Diabetes Research
• Stable Isotope Metabolomics
• +۳ مورد دیگر

Dr. Irwin J. Kurland is an Associate Professor in the Department of Medicine (Endocrinology) at Albert Einstein College of Medicine. He directs the Stable Isotope Metabolomics Core within the Diabetes Research Center. His research focuses on understanding metabolic inflexibility in diabetes and its relationship to insulin resistance, leveraging advanced stable isotope-based flux methodologies combined with 'omics approaches. Dr. Kurland’s work integrates GC/MS profiling, metabolomics, and proteomics to dissect tissue-specific metabolic networks and their regulatory mechanisms, particularly involving acetyl CoA signaling and protein acetylation. Research Interests: Dr. Kurland investigates how metabolic dysregulation impacts cellular signaling pathways, emphasizing the role of acetyl CoA as a metabolic sensor. His lab develops tiered frameworks for metabolic analysis, starting with whole-body phenotyping (e.g., HR-dGTT tests) to guide multi-omic studies. Key areas include: Metabolic flexibility and fuel switching Acetylation-driven enzyme regulation Animal models of insulin resistance (e.g., PPAR alpha-null, MKR mice) Systems biology approaches to diabesity Publications Highlight: Dr. Kurland has contributed to seminal studies on Sirt6’s role in glucose homeostasis, lipogenesis regulation via CDK8, and the metabolic acetylome’s role in fuel switching. His work bridges basic research with translational applications, including patented methodologies like the hepatic recycling deuterated glucose tolerance test (HR-dGTT). Labs/Teams: As director of the Stable Isotope Metabolomics Core, he oversees cutting-edge facilities for flux phenotyping and metabolomic analysis. Collaborations with labs such as Accili, Haeusler, and Mostoslavsky expand his research into integrative metabolic networks and epigenetic regulation.

• Tuberculosis Pathogenesis
• Mycobacterium tuberculosis
• Cell Wall Physiology
• +۳ مورد دیگر

Christopher M. Sassetti is a Professor in the Department of Microbiology at the University of Massachusetts Chan Medical School (UMass Chan Medical School) and T.H. Chan School of Medicine. His research focuses on the pathogenesis of Mycobacterium tuberculosis, specifically understanding how the bacterium adapts to host environments, acquires nutrients, regulates its cell wall physiology, and survives antibiotic treatment. He completed his BS in Biology at Santa Clara University and his PhD in Immunology at the University of California, San Francisco. Dr. Sassetti leads the Sassetti Lab, which employs genetic, biochemical, and systems biology approaches to study tuberculosis. His work has identified critical metabolic pathways and survival mechanisms in M. tuberculosis, including cholesterol utilization and cell wall synthesis regulation. He holds additional academic roles in the Morningside Graduate School of Biomedical Sciences, including the Immunology and Microbiology Program, MD/PhD Program, and Postbaccalaureate Research Education Program. Recent research highlights include studies on host immune responses to tuberculosis, antibiotic efficacy under infection conditions, and the role of genetic interactions in pathogen survival. His lab has discovered that host fatty acid metabolism and autophagy pathways play key roles in restricting bacterial growth. Dr. Sassetti has been recognized as a Damon Runyon Foundation Scholar and has contributed to high-impact publications in Immunity , Science , and Cell . Current projects include understanding nutrient acquisition in vivo, phosphosignaling regulation of cell wall synthesis, and metabolic mechanisms driving antibiotic tolerance. Collaborative efforts with institutions like the Morningside Graduate School and global networks drive translational research toward novel tuberculosis therapies and vaccines.

Dagmar Wirthمشاهده پروفایل

استاد پژوهشی

• Virology
• Immunology
• Gene Regulation
• +۴ مورد دیگر

Prof. Dagmar Wirth is a Research Professor and Head of the 'Model Systems for Infection and Immunity' research group at the Helmholtz Centre for Infection Research (HZI). Her work focuses on gene regulation, viral infections, and immune evasion mechanisms, with a particular emphasis on developing genetically modified mouse models for studying infectious diseases and immune responses. She leads the Service Unit 'Transgenic Mice' (TGSM), providing expertise in transgenic model systems to the HZI community. Affiliations: HZI (since 2004), previously at the Medical University of Hannover. Education: Chemistry studies in Braunschweig, PhD at GBF (now HZI), postdoctoral research on viral recombination and gene therapy. Her research interests include viral pathogenesis (e.g., Kaposi's sarcoma-associated herpesvirus), engineered cell-based therapies, and controlled drug delivery systems using macrophages and nanoparticles. She has pioneered models for hepatitis C virus infection in mice and developed biosensors to detect bacterial infections. Publications: Over 150 peer-reviewed articles, focusing on virology, immunology, and genetic engineering. Recent work includes studies on antibacterial coatings for implants, ultrasound-activated drug release, and the role of senescence in herpesvirus infection. Labs/Teams: Leads the MSYS group and collaborates with teams in virology, immunology, and biomedical engineering. Active in developing 3D in vitro models for studying infection and immune responses.

Che Colpittsمشاهده پروفایل

استادیار

• Virology
• Innate immunity
• Cell biology
• +۳ مورد دیگر

Dr. Che Colpitts is an Assistant Professor in the Department of Biomedical and Molecular Sciences at Queen's University, affiliated with the Faculty of Health Sciences and the Translational Institute of Medicine (TIME). She holds a PhD in Virology from the University of Alberta (2014), and completed postdoctoral training at the University of Strasbourg and University College London. Her research focuses on understanding how positive-sense RNA viruses, including hepatitis C virus (HCV), dengue virus, and coronaviruses, manipulate host cell biology to replicate and evade immune responses. Key research areas include: (1) roles of cyclophilin A in HCV immune evasion, (2) membrane rearrangements during viral replication, (3) TLR4 activation by viral glycoproteins, and (4) antiviral strategies targeting viral entry mechanisms. Current teaching includes MICR 451/BMED 851. The Colpitts Lab actively collaborates on projects involving ER stress responses, glycobiology, and broad-spectrum antiviral development. Notable recent publications explore SARS-CoV-2 pathogenesis, cyclophilin-mediated viral cloaking, and pan-coronavirus inhibitors. Her work bridges basic virology with translational medicine, aiming to identify novel antiviral approaches against emerging and untreatable viral threats.

Lois Mulliganمشاهده پروفایل

استاد

• Cancer
• Biochemistry
• Proteomics
• +۹ مورد دیگر

Lois Mulligan is a Professor in the Department of Pathology and Molecular Medicine at Queen's University. She holds cross-appointments in Pediatrics, Biomedical and Molecular Sciences, and is a Principal Investigator at the Queen's Cancer Research Institute. Her research focuses on the molecular mechanisms of the RET receptor tyrosine kinase in cancer, particularly thyroid, adrenal, and pancreatic tumors. She has expertise in molecular and cellular biology, protein manipulation, and confocal microscopy. Education includes a PhD in Medical Genetics from Queen's University (1993), post-doctoral training in cancer genetics at the Ludwig Institute (1990), and a Doctorate in Human Genetics (1986). She teaches courses in experimental cancer therapeutics and cancer biology. Mulligan's research investigates how RET dysregulation contributes to oncogenesis, with a focus on isoform-specific signaling, membrane dynamics, and therapeutic targets. Recent work includes studies on TMEM127 tumor suppression and GFRα ligand interactions. Her lab uses models like 3D spheroids and CRISPR screens to dissect RET pathways. Affiliations include the Queen's Cancer Research Institute and Endocrine-Related Cancer journal. Her work bridges basic science and translational oncology, emphasizing personalized medicine approaches.

Cranos Williamsمشاهده پروفایل

استاد

• Agricultural Analytics
• Machine Learning
• Artificial Intelligence
• +۳ مورد دیگر

Dr. Cranos Williams is the Goodnight Distinguished Professor of Agricultural Analytics at North Carolina State University, holding primary and secondary appointments in the Department of Electrical and Computer Engineering and the Department of Plant and Microbial Biology, respectively. He serves as Platform Director of the NC Plant Sciences Initiative and leads the EnBiSys Research Laboratory. His research integrates electrical engineering methodologies with plant biology to address challenges in biofuel production, environmental adaptability, and stress resilience in plants. Dr. Williams holds a Ph.D. in Electrical Engineering from NC State (2008), an M.S. from the same institution (2002), and a B.S. from NC A&T State University (2001). His work focuses on applying machine learning, signal processing, and systems analysis to quantify genetic and environmental impacts on plant responses. His research highlights include advancing sweetpotato quality assessment via AI, studying gene expression dynamics in Drosophila, and developing high-throughput phenotyping tools. His articles span topics like plant microbiome analysis, freezing tolerance mechanisms, and diversity in STEM education. Dr. Williams has received notable awards, including the University Faculty Scholar (2023), Alumni Association Outstanding Research Award (2021), and Alcoa Foundation Engineering Research Achievement Award (2019). He advocates for broadening participation in STEM and leads initiatives like the GRAD-AID for Ag program to train AI-driven plant science researchers. As head of EnBiSys Lab, Dr. Williams fosters interdisciplinary innovation at the intersection of engineering, data science, and agriculture. His contributions bridge computational tools and biological systems to address global agricultural challenges.

Arnaud Augertمشاهده پروفایل

استادیار

• Small Cell Lung Cancer (SCLC)
• Transcriptional and Epigenetic Mechanisms
• Cancer Biology
• +۴ مورد دیگر

Dr. Arnaud Augert is an Assistant Professor in the Department of Pathology at Yale School of Medicine, with a primary affiliation in the Genomics program. He leads the Augert Lab, focusing on dissecting transcriptional and epigenetic mechanisms in cancer, particularly small cell lung cancer (SCLC). His research integrates cell biology, genetics, and molecular biology to identify novel therapeutic strategies. Education: Dr. Augert holds a PhD in Molecular & Cellular Biology from the Pasteur Institute/Université de Sciences et Techniques de Lille (USTL), an MPhil in Cellular Biology & Physiology from USTL, and a BS in Cellular Biology from the University of Valencia. Research Interests: Dr. Augert’s work centers on understanding tumor suppressor networks, SCLC pathogenesis, and therapeutic targets such as MAX, NOTCH, and epigenetic regulators. His lab explores mechanisms of transcriptional addiction, metabolic rewiring, and cellular senescence in cancer progression. Publications: His research has been featured in top journals like Cancer Cell , Cancer Discovery , and Science Signaling , highlighting breakthroughs in SCLC biology and therapeutic approaches. Recent work includes studies on MAX inactivation, NOTCH inhibition, and epigenetic drivers of cancer. Scientific Awards: ATIP-AVENIR program UALC/LCRF grant Yale Cancer Center K12 Calabresi Immuno-Oncology Training Program Advising & Mentorship: Dr. Augert has mentored numerous trainees, including undergraduates, graduate students, and postdoctoral fellows. Current lab members include Yale BBS graduate students (Danny Gallant, Mileena Nguyen) and postdoctoral researchers (Bomiao Hu, Aoqun Song). Lab Activities: The Augert Lab is part of Yale Cancer Center and collaborates with interdisciplinary teams in Computational Biology, Molecular Medicine, and Pharmacology. They aim to bridge basic science discoveries with translational oncology.