جست‌وجوی استاد و پژوهشگر

Leonardo Schironeمشاهده پروفایل

پژوهشگر

• Cardiovascular Diseases
• Medical Genetics
• Molecular Mechanisms
• +۵ مورد دیگر

Leonardo Schirone serves as a Tenure-Track Researcher (RTT) in Medical Genetics at the Department of Health and Life Sciences, European University of Rome since 2024, where he teaches Biology and Genetics for the Medicine and Surgery Degree Course. His academic background includes a PhD in Molecular Medicine, followed by postdoctoral research at Sapienza University of Rome and IRCCS Neuromed. At IRCCS Neuromed, he led a PNRR-funded research unit investigating genetic determinants of chemotherapy-induced cardiotoxicity. Dr. Schirone's translational research focuses on: Molecular mechanisms in cardiovascular diseases Nutraceutical applications and autophagy modulation in preclinical models Genetics of cardiovascular pathologies Single-cell sequencing technologies applied to myasthenia gravis With over 35 peer-reviewed publications in international journals, he has received recognition through awards at national and international scientific conferences. He maintains active membership in leading professional societies including the American Heart Association, European Society of Cardiology, Italian Society of Cardiology, and Sigma Xi Honor Society. As an academic contributor, he serves as reviewer and guest editor for high-impact journals, co-authored two scientific volumes, and regularly supervises graduate theses while conducting educational seminars in biotechnology and translational medicine.

Abdel Rahman Abdel Fattahمشاهده پروفایل

پژوهشگر

• Mechanobiology
• Tissue Engineering
• Extracellular Matrix (ECM) Dynamics
• +۷ مورد دیگر

Abdel Rahman Abdel Fattah is a Principal Investigator at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, Austria. He previously held a postdoctoral position at CeMM (2022–2024) and KU Leuven (Belgium) (2018–2022). Education: BSc and PhD in Mechanical Engineering from McMaster University (Canada) Current Role: Lab Head at CeMM since 2024 Research Interests focus on multiscale mechanobiology, specifically how cells use mechanical forces and extracellular matrix (ECM) dynamics to coordinate tissue organization. His group combines bioengineered mechanical stimulation tools with advanced imaging and computational models to study: Dynamic Cellular and ECM Interactions in health and disease Mechano-Transcriptomic Mapping using spatial transcriptomics and atomic force microscopy (AFM) Computational Modeling of tissue organization via reaction-diffusion systems and positional information theory Disease Applications: Traumatic brain/spinal cord injuries and liver fibrosis Publications highlight interdisciplinary work across mechanobiology, bioengineering, and vascular pathology, with a focus on magnetic actuation, organoid modeling, and ECM dynamics. Articles appear in Nature Communications , Cell Reports , and Lab on a Chip . Recent studies (2024–2025) explore force-mediated vascular lesion growth and transcriptional hallmarks of aging using single-cell analysis. Technological Innovations include: Magnetic Microactuators for local organoid stimulation 3D Soft Microfluidic Systems for perfused tissues Diamagnetophoresis-Based Bioprinting Single-Cell Transcriptomic Atlases for mechanical stress responders

• Nanoparticle
• Nanomedicine
• Nitric Oxide
• +۱۴ مورد دیگر

María Navalón y López is a researcher affiliated with the Materials Engineering Group , focusing on nanotechnology applications in biomedical and pharmaceutical sciences. Her work centers on nanoparticle design , nitric oxide delivery , and transfection mechanisms , particularly for treating liver diseases like portal hypertension in cirrhotic models. Recent Research Themes: Nanoparticle engineering for targeted drug delivery Nitric oxide donor systems in hemodynamic regulation Poly(beta-amino ester) (pBAE) polyplexes for rational nanocarrier formulations mRNA-loaded nanoparticles in vaccination and therapeutic contexts Scientific Contributions: Developing liver-targeted nanocarriers to mitigate portal hypertension Innovative polyplex expansion microscopy (PExM) for cell trafficking analysis Investigating structure-function relationships in pBAE/polynucleotide systems

• Plant Glycobiology
• Optical Microscopy
• Digital Holography
• +۳ مورد دیگر

Samira Ebrahimi is an Academic employee in the Department of Plant and Environmental Sciences at the University of Copenhagen, specifically within the Section for Plant Glycobiology. Her research integrates advanced optical engineering with plant science to develop novel imaging methodologies for studying plant cellular structures and dynamics. Her primary research domains include: Plant Glycobiology: Investigating glycan structures and functions in plant development Optical Microscopy: Pioneering label-free imaging techniques including quantitative phase imaging Digital Holography: Developing computational methods for 3D plant cell visualization Starch Chemistry: Analyzing structural properties of plant starches using NMR spectroscopy AI in Plant Science: Implementing machine learning for subcellular tracking Biophysics: Quantifying mechanical properties of plant cell walls Analysis of her 2022-2025 publications reveals a strong trajectory toward AI-enhanced microscopy systems, with significant focus on portable instrumentation for field applications and computational approaches to replace fluorescent labeling. Her work demonstrates increasing interdisciplinary collaboration between plant biology, optical physics, and computer science. Scientific Awards: No scientific awards mentioned in available documentation Advising and Grants: No information regarding student supervision or research grants provided in source materials Laboratory Affiliations: Core member of the Section for Plant Glycobiology at the University of Copenhagen, focusing on structural and functional analysis of plant carbohydrates

Jane E. Parkerمشاهده پروفایل

استاد

• Plant Immunity
• Plant-Microbe Interactions
• Molecular Plant Pathology
• +۴ مورد دیگر

Jane E. Parker is a Professor and Research Group Leader at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, where she leads the "Resistance pathway dynamics in plant immunity" research group within the Department of Plant-Microbe Interactions. She has been a Principal Investigator in the Cluster of Excellence on Plant Sciences (CEPLAS) since 2012 and maintains extensive national and international collaborations in plant immunity research. Professor Parker's research focuses on plant immunity mechanisms, particularly how plants detect invading pathogens and activate defense pathways. Her laboratory investigates TIR-domain enzymatic activities, NLR immunity, and plant-microbe interactions using approaches ranging from genetics, CRISPR-Cas9 technology, RNA-seq, ChIP-seq, to protein biochemistry and structure-function analyses. Current projects include NLR immunity decision-making, biotic stress network architectures across plant lineages, tracking immune-stimulating nucleotides, and defense metabolites impacting plant interactions with beneficial and pathogenic fungi. Her recent publications demonstrate a strong focus on the biochemical mechanisms of plant immune receptors, particularly TIR-domain proteins and NLR receptors, with applications across plant species from Arabidopsis to crops like rice and barley. This work has revealed conserved working principles while also identifying clade-specific variations in defense signaling modules. Elected as International Member of The US Academy of Sciences (NAS), 2023 Elected as Fellow of The Royal Society (FRS), 2023 Elected to Academy of Europe, 2017 Elected to EMBO, 2016 Elected to Leopoldina German National Academy of Sciences, 2013 Max-Planck Society 'C3' Independent Research Fellowship, 2004-2009 Alexander von Humboldt 'Sofja Kovaleskaja' award, 2001 Professor Parker leads an active research group with multiple postdocs, students, and technicians. She has served on numerous editorial boards including Science, Trends in Plant Science, and Current Opinion in Plant Biology. As a Principal Investigator in CEPLAS, she has coordinated plant-microbe sections and served on various grant review panels for organizations including DFG, ERC, and NSF. The Parker lab maintains state-of-the-art facilities for plant molecular genetics, biochemistry, and imaging. They collaborate extensively with structural biologists, organic chemists, and computational biologists to advance understanding of plant immune mechanisms. The lab is part of the CEPLAS research infrastructure, which includes specialized platforms for plant microbiota studies, synthetic biology, and data science.

Rüdiger Simonمشاهده پروفایل

استاد پژوهشی

• Plant Developmental Biology
• Meristem Signaling Pathways
• Plant Stem Cell Regulation
• +۵ مورد دیگر

Prof. Dr. Rüdiger Simon serves as Research Professor at the Institute of Developmental Genetics, Heinrich Heine University Düsseldorf, where he leads investigations into intercellular signaling pathways governing plant shoot and root meristem development. His work centers on how meristems—harboring stem cells that determine growth capacity, organ generation, and root architecture—utilize regulatory networks for plant architecture control and plasmodesmata-mediated cytoplasmic communication. Simon's research spans four integrated scientific concepts: RA1 optimizing plant performance through development-metabolism interfaces; RA2 plant-microbiota metabolic networks in soil adaptation; RA3 synthetic and reconstruction biology approaches; and RA4 theoretical plant biology with data science integration. His group employs specialized facilities including the Plant Metabolism and Metabolomics Facility and Imaging Platform, contributing to CEPLAS Data resources and public toolsets for the plant science community. Analysis of his 30-year publication record reveals persistent focus on Arabidopsis thaliana stem cell regulation, with recent expansion into proteomics (2023 plasmodesmata proteome study) and data science. Key recurring themes include CLE peptide signaling pathways, receptor kinase complexes, and calcium-mediated cell fate determination—demonstrating evolution from foundational work on CLV3 feedback loops (Science 2000) to current systems-level investigations of meristem communication networks. As part of CEPLAS (Cluster of Excellence on Plant Sciences), Simon maintains active research programs supported by ongoing funding cycles beyond the archived 2013-2018 period, evidenced by 2023 publications and operational facilities. His work bridges molecular genetics, cell biology, and computational approaches to address fundamental questions in plant development.

• Nanodiamond Quantum Sensing
• Quantum Sensors
• Intracellular Parameter Measurement
• +۳ مورد دیگر

Dr. Yingke Wu serves as Group Leader of the Nanodiamond Group at the Max Planck Institute for Polymer Research (MPIP) in Mainz, Germany, a position he assumed in 2022 after completing his doctorate at the same institution. His academic qualifications include: Bachelor of Science in Polymer Materials and Engineering from Hebei University of Technology (Tianjin, China), 2014 Master of Science in Polymer Science and Engineering from Sichuan University (Sichuan, China), 2017 Doctorate from the Max Planck Institute for Polymer Research under Prof. Tanja Weil, 2021 Dr. Wu's research pioneers the application of nanodiamond quantum sensing technology for in-situ measurement and manipulation of intracellular parameters—including temperature, pH, and radical species—in living biological systems. His work addresses critical limitations of conventional nanoscale measurement techniques by developing sensors operable under physiological conditions, bridging quantum physics, polymer science, and medical diagnostics to solve fundamental challenges in understanding biological complexity. Analysis of his 2021-2022 publications reveals a concentrated research trajectory advancing nanodiamond-based quantum sensing for biomedical applications, with emphasis on hydrogen peroxide detection, intracellular thermometry, and light-controlled theranostic platforms. These works demonstrate cross-disciplinary innovation spanning chemistry, materials engineering, and clinical medicine, particularly in developing real-time intracellular monitoring tools for dynamic biological processes. Dr. Wu actively contributes to Collaborative Research Center SFB1279, which investigates the human peptidome for novel antimicrobial and anti-cancer therapeutic development. The Nanodiamond Group operates at the forefront of quantum biotechnology, developing next-generation sensing platforms that could transform fundamental biological research and clinical diagnostics through precise nanoscale environmental monitoring in living cells.

Angel P. Tabancay Jr.مشاهده پروفایل

استادیار

• Pharmacy Education
• Signal Transduction Pathways
• Cancer Research
• +۸ مورد دیگر

Angel P. Tabancay Jr. is an Assistant Professor (Teaching Track) in the Department of Pharmacology and Pharmaceutical Sciences at the University of Southern California (USC) School of Pharmacy. He joined the USC Mann faculty in July 2015 with primary teaching responsibilities in the PharmD program across multiple years of the curriculum. Dr. Tabancay also contributes to the MS program in Pharmaceutical Sciences, teaching about drug mechanisms and research methodology. Dr. Tabancay received his educational training at the University of California, Los Angeles, where he earned his BS in Molecular, Cell, and Developmental Biology in 1998, followed by a PhD in Microbiology, Immunology, and Molecular Genetics in 2004. His doctoral research focused on 'Genetic approaches to the study of Rheb GTPase' using model organisms Saccharomyces cerevisiae and Schizosaccharomyces pombe. He subsequently completed postdoctoral training at the University of Southern California in the lab of Susan L. Forsburg, continuing his work with Schizosaccharomyces pombe to investigate DNA replication. Dr. Tabancay's research spans multiple interconnected domains at the intersection of basic science and pharmaceutical education. His primary research interests include pharmacy education methodologies, signal transduction pathways involved in cancer development, DNA replication mechanisms, and the application of model organisms to understand human diseases. His expertise encompasses molecular genetics, microbiology, cellular biology, molecular biology, immunology, and yeast genetics, providing a strong foundation for his interdisciplinary approach to both research and teaching. Analysis of Dr. Tabancay's publication record reveals a consistent focus on molecular mechanisms of cell growth and regulation, particularly centered around the Rheb GTPase protein family and DNA replication processes. His early work established foundational knowledge about Rheb's role in nutrient sensing, arginine uptake, and cell cycle progression using yeast models. Later publications expanded this research to examine chromatin context in DNA replication, demonstrating how epigenetic factors influence fundamental cellular processes. This trajectory shows a researcher who successfully bridges basic molecular biology with potential therapeutic applications. Dr. Tabancay has made significant contributions to pharmaceutical education through his teaching and course coordination responsibilities. In the PharmD program, he coordinates and teaches Biological Systems I and II for first-year students, co-coordinates General Medicine Therapeutics for second-year students, and teaches Pharmacy Education courses for students interested in academic careers. He also coordinates the Scholarly Project course for third-year students. Within the MS program, he teaches about Drug Transporters, Anticancer Agents, and Principles of Research Methodology, demonstrating his commitment to developing the next generation of pharmaceutical scientists.

Olle Tereniusمشاهده پروفایل

پژوهشگر

• Insect Microbiota
• Vector Biology
• Silkmoth Virology
• +۴ مورد دیگر

Olle Terenius is a Researcher at the Department of Cell and Molecular Biology at Uppsala University, with additional roles as Project Coordinator at the International Science Programme (ISP) and the University Library's Scholarly Communications Division. His work bridges microbiology, entomology, and vector control research with significant international collaborations across China, India, Thailand, and the Amazon Basin. Dr. Terenius's research primarily focuses on insect microbiota as a proxy for tracking insect movement in natural environments . He has developed innovative methods to determine which environments insects have visited, enabling identification of individuals from similar locations. His work also extends to virus research in silkmoths through collaborations with researchers in Asia, examining diseases affecting tasar silkworms and traditional sericulture practices. Analysis of Terenius's recent publications (2021-2025) reveals three dominant research trajectories: intensive investigation of mosquito microbiology (particularly Anopheles species in malaria-endemic regions), comprehensive studies on probiotic applications for silkworm health (focusing on Lactobacillus species against pathogens like Nosema bombycis and BmNPV), and exploration of Amazonian microbial communities for vector control applications. His work spans from fundamental microbial ecology to practical disease control solutions. While no specific scientific awards are explicitly documented in the available information, Terenius's research demonstrates significant impact through citations across multiple platforms including social media, Wikipedia pages, policy documents, and patent references. His publications consistently feature international co-authorship, particularly with researchers from malaria-endemic regions of Brazil, Thailand, and India. Dr. Terenius maintains active research in both laboratory and field settings, with recent work emphasizing the environmental determinants of mosquito microbiota and the development of microbial-based interventions for silkworm disease management. His dual focus on fundamental insect-microbe interactions and practical applications for disease control and sericulture represents a comprehensive approach to entomological research with tangible real-world implications.

• Sleep Medicine
• Circadian Rhythms
• Sleep Deprivation
• +۹ مورد دیگر

Charles Andrew Czeisler is the Frank Baldino, Jr., Ph.D. Professor of Sleep Medicine at Harvard Medical School, with clinical appointments at Brigham and Women's Hospital Division of Sleep and Circadian Disorders. He directs significant research initiatives including the Sleep Matters Initiative at Brigham Health and co-founded the Harvard Work Hours Health and Safety Group. His work bridges basic circadian science with clinical applications and public health policy. Dr. Czeisler completed his A.B. magna cum laude in Biochemistry and Molecular Biology at Harvard College (1974), followed by a Ph.D. in Neuro- and Biobehavioral Sciences at Stanford University (1978) under William C. Dement, an M.D. from Stanford University School of Medicine (1981), and a Senior Fellowship in Health Policy at Harvard's Kennedy School of Government (1983). His laboratory research focuses on the neurobiology of the human circadian pacemaker in the suprachiasmatic nucleus and its interaction with the sleep homeostat. Current investigations examine melatonin's role in sleep organization, photic resetting mechanisms through intrinsically photosensitive retinal ganglion cells containing melanopsin, and how circadian/homeostatic processes regulate sleep and neurobehavioral function. His team studies novel wake-promoting countermeasures, exercise effects on circadian rhythms, fMRI of sleep-deprived brains, aging influences on sleep, chronic sleep restriction impacts, and space flight effects on circadian rhythms. Analysis of Dr. Czeisler's recent publications reveals a strong emphasis on translational research connecting basic circadian science with clinical applications. His work increasingly examines sleep's relationship with long COVID, mental health, occupational safety (particularly for medical residents and transportation workers), and technological approaches to sleep assessment. The research demonstrates growing interdisciplinary collaboration across sleep medicine, public health, digital health technology, and policy development. Aschoff's Rule International Award in Circadian Biology (2001) Lifetime Achievement Award, National Sleep Foundation (2008) Lord Adrian Gold Medal, Royal Society of Medicine (2008) Election to National Academy of Medicine (2010) NASA Johnson Space Center Director's Innovation Award (2014) Peter C. Farrell Prize in Sleep Medicine (2019) Establishment of Annual Charles A. Czeisler Lectureship, Monash University (2023) Sleep Hero Award (2024) Dr. Czeisler has mentored numerous researchers who have become leaders in sleep medicine, including Robbins, Weaver, Barger, Quan, and Duffy. His research is supported by multiple active grants including a $5.8 million Department of Defense project developing a blood test to measure sleep deprivation, an international task force on sleep/circadian rhythms and youth depression funded by Wellcome Trust, and clinical trials investigating treatments for shift work disorder. His work has directly influenced policies on medical resident work hours, airline crew scheduling, and daylight saving time. Dr. Czeisler leads the Division of Sleep and Circadian Disorders at Brigham and Women's Hospital and the Harvard Medical School Division of Sleep Medicine. Through the Sleep Matters Initiative, his team applies circadian research to night workers including medical residents and police. His laboratory collaborates with NASA on space flight circadian research and with the International Association of Circadian Health Clinics on global implementation of circadian medicine principles.

Hidde Ploeghمشاهده پروفایل

استاد

• Immunology
• Biochemistry
• Antigen processing and presentation
• +۶ مورد دیگر

Hidde Ploegh is a Professor in the Department of Immunology at Harvard Medical School, where he leads a research laboratory at Boston Children's Hospital. His work bridges biochemistry and immunology, with a focus on understanding immune recognition mechanisms and pathogen evasion strategies. Harvard Medical School, Department of Immunology Boston Children's Hospital research lab Extensive research in molecular immunology and protein engineering Dr. Ploegh's research focuses on the biochemistry of immune recognition, particularly antigen processing and presentation through MHC molecules. His lab pioneered the use of 'sortagging' techniques and alpaca-derived nanobodies for both fundamental research and therapeutic applications. Current work emphasizes using nanobodies for non-invasive imaging of immune responses, particularly through positron emission tomography (PET), and developing novel approaches to modulate immune responses for cancer and autoimmune diseases. The Ploegh lab's publication record demonstrates consistent contributions to understanding immune recognition, with recent work highlighting applications of nanobody technology across immunology, cancer research, and protein engineering. Their research shows a clear trajectory from fundamental biochemical studies toward translational applications. Extensive work on nanobody technology and applications Innovative approaches to protein modification using enzymatic methods Development of imaging techniques for immune responses Applications in cancer immunotherapy and autoimmune disease Dr. Ploegh's laboratory has secured significant research funding to support their work on immune recognition mechanisms and nanobody applications. The lab actively trains graduate students and postdoctoral fellows, contributing to the next generation of immunologists and protein engineers. Recent collaborations demonstrate strong connections with clinical researchers working on cancer immunotherapy and autoimmune diseases. The Ploegh lab utilizes advanced techniques including sortase-mediated protein labeling, nanobody engineering, and mouse models of immune response. They maintain strong collaborations with chemistry and imaging specialists to advance their research goals, particularly in developing new approaches for visualizing and modulating immune responses.

Anne Claire Conibearمشاهده پروفایل

استادیار

• Protein chemistry
• Peptide chemistry
• Chemical biology
• +۴ مورد دیگر

Anne Claire Conibear is an Assistant Professor (Tenure Track) in Protein Chemistry at the Faculty of Technical Chemistry, TU Wien (Vienna University of Technology), Austria. She also holds an Honorary Research Fellow position at the School of Biomedical Sciences, The University of Queensland. Her research focuses on using protein and peptide chemistry tools to create site-specifically modified proteins to study post-translational modifications in biological processes. Dr. Conibear's research interests include: Protein and peptide chemistry Chemical biology Post-translational modifications Protein synthesis and semi-synthesis Structural biology NMR spectroscopy Her current research projects focus on understanding how posttranslational modifications of HMGN1 regulate DNA packaging and how phosphorylation regulates β-catenin in oncogenic signaling. She develops chemical tools to create specifically modified proteins that allow precise investigation of how these modifications affect protein structure and function. Dr. Conibear has received several prestigious awards including the Boulder Peptide Foundation Danho Young Investigator Award (2025) and multiple Career Track Awards from the University of Queensland. She supervises multiple PhD students and has successfully mentored several graduate students through their theses. Her teaching includes courses on biomolecule synthesis, bachelor seminars, and foundational chemistry laboratories at TU Wien.

• Hematology
• Oncology
• Liquid Biopsy Development
• +۳ مورد دیگر

Nicholas Bingham serves as an Adjunct Research Fellow at the Australian Centre for Blood Diseases, Monash University, focusing on hematological malignancies and diagnostic innovation. His work integrates proteomics, liquid biopsy development, and molecular diagnostics to address challenges in multiple myeloma detection and monitoring. Dr. Bingham's research spans hematology , oncology , and proteomics , with emphasis on: Liquid biopsy optimization for early cancer detection Extracellular vesicle characterization in tumor microenvironments Mass spectrometry-based minimal residual disease assessment Molecular stratification of high-risk myeloma subtypes His publications demonstrate consistent advancement in translating proteomic findings into clinical diagnostics, particularly through blood-based biomarker discovery. Current research trends emphasize non-invasive monitoring techniques, with recent work establishing DNA copy number variations and clonotypic assays as critical tools for identifying smouldering myeloma progression. Collaborative projects integrate flow cytometry, mass spectrometry, and genomic analysis to refine risk stratification models. Dr. Bingham leads the 2024-2025 project Establishing blood-based liquid biopsies for early detection of high-risk multiple myeloma as Primary Chief Investigator, collaborating with Spencer, Reynolds, and Mithraprabhu. This NHMRC-funded initiative builds on his team's prior work in extracellular vesicle proteomics and MYC DNA analysis. His laboratory work centers on the Australian Centre for Blood Diseases' myeloma research program, utilizing: Plasma extracellular vesicle isolation protocols Mass spectrometry clonotypic assays (EasyM) EuroFlow-based minimal residual disease tracking Stromal cell interaction models Future directions include validating liquid biopsy markers for clinical implementation and expanding high-risk myeloma detection to pre-symptomatic stages.

• Membrane Biology
• Cellular Biophysics
• Synaptic Vesicle Fusion
• +۳ مورد دیگر

Frederic Pincet, PhD is an Associate Research Scientist in the Department of Cell Biology at Yale School of Medicine. He leads research in membrane dynamics, synaptic vesicle fusion, and protein-lipid interactions within the Rothman Lab . His work combines biophysical techniques with cell biology to study fundamental mechanisms of membrane remodeling and fusion processes. Education : Received his PhD from École Normale Supérieure de Paris (1994). Research Interests : SNARE protein complexes and their role in exocytosis Membrane curvature and tubulation mechanisms Collagen secretion pathways via intercompartmental continuities α-synuclein-induced membrane dysfunction in neurodegenerative diseases Development of photosensitive nanoprobes for vesicle isolation Recent Trends in Publications : His 2024 work focuses on synaptotagmin oligomerization dynamics and novel extracellular vesicle isolation techniques. Recent studies highlight dual-ring SNAREpin machinery regulation and membrane protein interactions in reduced dimensions. Ongoing research explores collagen secretion mechanisms and mitochondrial membrane control via apolipoproteins. Labs/Teams : Active contributor to the Rothman Lab , collaborating closely with James E. Rothman (Nobel Laureate in Physiology/Medicine).

Victor Hatiniمشاهده پروفایل

دانشیار

• Developmental Biology
• Cell Biology
• Molecular Biology
• +۳ مورد دیگر

Victor Hatini is an Associate Professor in the Department of Developmental, Molecular and Chemical Biology at Tufts University School of Medicine. His research focuses on understanding the mechanisms controlling epithelial morphogenesis, particularly using the Drosophila retina as a model system. He investigates the roles of adhesion molecules like Sidekick (Sdk) in coordinating contractile and protrusive forces during tissue organization. His work has revealed critical insights into tricellular adherens junction dynamics and their role in developmental processes. Education: PhD, Cornell University, 1996 MSc, Weizmann Institute of Science, 1991 BSc, Hebrew University, 1989 Research Interests: Dr. Hatini studies how adhesion molecules and cytoskeletal networks regulate epithelial tissue organization. His lab explores pulsatile mechanical cycles in epithelial cells, focusing on Sidekick’s dual roles in modulating actomyosin contraction and actin branching. Current work emphasizes the formation and function of tricellular junctions, with implications for understanding diseases involving tissue disorganization. Teaching & Mentoring: Dr. Hatini contributes extensively to graduate education at Tufts, directing core courses such as Cell Behavior and Molecular Cell Biology of Development. He has mentored 18 graduate students, 5 postdoctoral fellows, and 5 technicians, many of whom have pursued successful careers in academia, industry, and medicine. He also serves on NIH study sections supporting early-career researchers. Awards: Tufts Collaborates Award (2014) Grants: Active funding includes NIH grants investigating the WAVE regulatory complex in epithelial morphogenesis (2018–2023) and prior support for cellular interactions in patterning (2004–2009). Labs & Teams: His laboratory at Tufts focuses on integrative approaches combining genetics, live imaging, and computational modeling to study epithelial dynamics. Collaborations emphasize bridging basic research with clinical relevance in tissue repair and disease.