جست‌وجوی استاد و پژوهشگر

Hesham Fahmyمشاهده پروفایل

دانشیار

• Medicinal Chemistry
• Drug Design
• Synthetic Organic Chemistry
• +۵ مورد دیگر

Hesham Fahmy is an Associate Professor in the Department of Pharmaceutical Sciences at South Dakota State University's College of Pharmacy and Allied Health Professions. His academic roles include teaching core courses such as Medicinal Chemistry I/II, Pharmacology, and advanced graduate-level drug discovery modules. He holds a Ph.D. in Medicinal Chemistry and has extensive experience in drug design targeting neuroendocrine and oncological disorders. His research focuses on developing novel small molecules as corticotropin-releasing factor receptor antagonists, T-/L-type calcium channel blockers, and marine-derived natural products for chemoprevention. Key areas include skin cancer prevention using cembranoid derivatives and structure-based design of anticancer agents. He has secured patents for salvinorin analogs and cembranoid chemopreventive compounds. Fahmy's work bridges synthetic organic chemistry with pharmacological evaluation, emphasizing translational research. His lab explores synergistic drug combinations for enhanced cancer therapy and investigates mechanisms of action for natural product-derived compounds. He actively contributes to curricular development and assessment committees within the College. Education: B.S. Pharmacy, M.S. Pharmaceutical Chemistry, Ph.D. Medicinal Chemistry Active patents: WO 2006012643, WO 2003095404 Key research programs: CRF receptor antagonists development, marine natural products' anticancer potential

• Cell Mechanics
• Tissue Dynamics
• Mechanobiology
• +۴ مورد دیگر

Raimon Sunyer Borrell is a Researcher at the Institute for Bioengineering of Catalonia (IBEC), where he leads investigations within the Integrative Cell and Tissue Dynamics group. His work bridges biophysics, bioengineering, and cell biology to decipher how mechanical forces govern cellular and tissue behavior in physiological and pathological contexts. His primary research focuses on mechanobiology, particularly collective cell migration, durotaxis (stiffness-guided migration), and tissue dynamics. He investigates how cells sense mechanical cues through adhesion complexes like E-cadherin, with applications in understanding developmental processes, sleep apnea pathophysiology, and circadian rhythm disruptions. His interdisciplinary approach combines advanced experimental techniques—including atomic force microscopy, microfluidic platforms, and 3D tissue models—with computational modeling to quantify force transmission and tissue remodeling. Analysis of his 15 most recent publications reveals consistent innovation in developing physiomimetic models for disease study (e.g., intermittent hypoxia systems for sleep apnea) and fundamental discoveries about collective cell behaviors. His work demonstrates how mechanical coordination across cell clusters enables optimal migration through complex environments, with implications for regenerative medicine and tissue engineering. Dr. Sunyer actively contributes to IBEC's collaborative ecosystem, working within the Integrative Cell and Tissue Dynamics group that develops cutting-edge tools for probing cellular mechanics. His research directly supports IBEC's mission to translate fundamental discoveries into biomedical applications through interdisciplinary collaboration.

• Environmental Analytical Chemistry
• Per- and Polyfluoroalkyl Substances (PFAS)
• Groundwater Contamination
• +۳ مورد دیگر

Christian Zwiener is a Professor (W3) for Environmental Analytical Chemistry at the Center for Applied Geoscience, University of Tübingen since 2009. He holds a Habilitation and Venia Legendi in Water Chemistry (KIT, 2004) and a Ph.D. in Water Chemistry (Technical University of Munich, 1995). His research focuses on PFAS analysis , non-target screening , and environmental fate of contaminants using high-resolution mass spectrometry . Education: Habilitation in Water Chemistry, KIT (2004) Ph.D. in Water Chemistry, Technical University of Munich (1995) Diploma in Analytical and Environmental Chemistry, University of Ulm (1989) Research Trends: PFAS contamination in soils , human hair , and textiles Non-target screening workflows for novel contaminants and transformation products Environmental fate of pharmaceuticals and biocides Development of HRMS data mining tools (e.g., FindPFΔS, PFΔScreen) Scientific Awards: Level II Scientific and Technological Achievement Award (STAA) , EPA (2008) Research Award , Water Chemical Society, GDCh (2001) Professional Service: Chairman, Journal Vom Wasser (2016–present) Delegate, EUChemS Division of Chemistry & Environment (2020–present) Member of Water Research Perspectives Commission (2018–present) Advisory Board, VEGAS, University of Stuttgart (2014–present) His work bridges analytical chemistry , environmental toxicology , and public health , with key contributions to PFAS contamination and CKDu groundwater links . He has developed standardized methods for PFAS analysis and electrochemical oxidation protocols for contaminant degradation.

Jonathan Dworkinمشاهده پروفایل

استاد

• Bacterial Persistence
• Antibiotic Tolerance
• Ribosome Biology
• +۵ مورد دیگر

Professor Jonathan Dworkin is a distinguished faculty member in the Department of Microbiology & Immunology at Columbia University's Vagelos College of Physicians and Surgeons. His research program investigates fundamental mechanisms of bacterial survival under stress, with particular emphasis on quiescent cell physiology and antibiotic tolerance phenomena. As a Fellow of the American Association for the Advancement of Science, he maintains an active laboratory employing multidisciplinary approaches spanning genetics, biochemistry, and single-molecule biophysics. Dr. Dworkin's research focuses on how bacteria survive nutrient limitation and other stresses through downregulation of protein synthesis, with major contributions to understanding ribosome hibernation via ppGpp signaling and Hibernation Promoting Factor. His work reveals how these molecular mechanisms contribute to antibiotic persistence and tolerance in pathogens. Current investigations examine nucleotide signaling networks, ribosome dimerization, and Ser/Thr phosphorylation systems that regulate bacterial dormancy. His recent publications demonstrate significant contributions to structural microbiology, bacterial signaling, and persistence mechanisms. Key findings include elucidating the structural basis of peptidoglycan synthesis complexes, demonstrating transcriptional regulation of ribosome hibernation, and characterizing how phosphorylation networks drive phenotypic variation in antibiotic tolerance. His laboratory employs innovative techniques including single-molecule imaging, in vitro reconstitution, and chemical biology approaches. Fellow, American Association for the Advancement of Science Professor Dworkin maintains an active research program with substantial grant funding supporting investigations into bacterial persistence mechanisms. His laboratory serves as a training ground for graduate students and postdoctoral researchers pursuing careers in microbiology and infectious disease research. While specific student names aren't listed in available materials, his publications show consistent mentorship of junior researchers through co-authorship on significant publications. The lab maintains strong collaborations with structural biologists and chemical biologists to advance understanding of bacterial stress survival. Dr. Dworkin's laboratory investigates fundamental questions of bacterial physiology with implications for antibiotic development. His team employs a comprehensive toolkit including genetic manipulation, biochemical reconstitution, single-molecule microscopy, and structural analysis to dissect molecular mechanisms of persistence. Current work focuses on ribosome protection systems, nucleotide signaling networks, and phosphorylation cascades that regulate bacterial dormancy states.

• Nanoparticle Drug Delivery
• Cancer Immunotherapy
• Macrophage Targeting
• +۴ مورد دیگر

Jennifer Fernández Alarcón serves as a Research Collaborator at IQS (Institut Químic de Sarrià), part of Universitat Ramon Llull's School of Engineering and Technology. Her work focuses on nanomedicine applications for cancer therapy and immunomodulation. Her research interests prominently feature Nanoparticle Drug Delivery , Cancer Immunotherapy , and Macrophage Targeting , with specific expertise in glycoconjugate-functionalized gold nanoparticles. The fingerprint analysis reveals strong activity in Macrophage biology (100%), Nanoparticle pharmacology (86%), Neoplasm research (60%), and Gold Nanoparticle applications (50%). Recent publications demonstrate consistent focus on therapeutic nanoparticle systems, particularly examining cellular uptake mechanisms, liver macrophage polarization, and cancer cell targeting. Her work bridges nanotechnology with immunology through innovative glycopeptide and diterpenoid modifications. She actively participates in collaborative projects including TECARN (2024-2026), focused on mRNA analysis for vaccination. Her advising role includes supervision of multiple research outputs across nanomedicine and gene therapy domains.

Björn Schefflerمشاهده پروفایل

استاد

• Translational Neurooncology
• Glioblastoma
• Cancer Stem Cells
• +۷ مورد دیگر

Prof. Dr. Björn Scheffler is a leading researcher in translational neuro-oncology at the University of Duisburg-Essen (UDE), affiliated with the Medical Faculty and the West German Cancer Center (WTZ). His lab operates as an extramural division of the German Cancer Research Center (DKFZ) in Heidelberg under the German Cancer Consortium (DKTK), emphasizing a strong bridge between basic research and clinical application. His research focuses on human brain tumors, particularly glioblastoma, using stem cell biology and patient-derived models. Key areas include phenotypic plasticity of treatment-resistant cancer cells, the role of the immune system in cancer progression, development of novel anticancer therapeutics, and biomarker discovery for early-phase clinical trials. The lab fosters interdisciplinary collaboration with clinical neuro-oncology units at University Hospital Essen and national/international academic and industry partners. The most recent publications highlight groundbreaking work in tumor-immune interactions, such as the discovery of cranioencephalic lymphoid units in glioblastoma and mechanisms of immune evasion. Other studies explore subclone dynamics, drug repurposing (e.g., niclosamide), and advanced 3D tumor modeling. Collectively, these works reflect a consistent trajectory toward understanding tumor heterogeneity, resistance mechanisms, and innovative therapeutic strategies in neuro-oncology. Helmholtz Doctoral Prize awarded to Dr. Celia Dobersalske, a researcher in Prof. Scheffler's group, for work published in Nature Medicine on skull bone immunity in brain tumors. Research has led to new insights into pseudoprogression in glioblastoma and melanoma brain metastases using advanced PET imaging techniques. Prof. Scheffler mentors a dynamic team of clinician scientists, medical researchers, and students. His lab receives funding through DKFZ, DKTK, and national research programs, supporting a robust pipeline from bench to bedside. The team operates within a specialized research environment at the Zentrum für Molekulare Biomedizin (ZMB), equipped with advanced facilities for molecular and cellular oncology.

Lakeshia J. Taiteمشاهده پروفایل

استادیار

• Biomaterials
• Cardiovascular Tissue Engineering & Regenerative Medicine
• Targeted Drug Delivery
• +۳ مورد دیگر

Lakeshia J. Taite is an Assistant Professor of Chemical Engineering at the University of Virginia's School of Engineering and Applied Science, holding a Research Track position within the Academic General Faculty. Her research focuses on designing biomaterials to engineer cell-instructive microenvironments for tissue regeneration, particularly in cardiovascular applications. She has held prior academic roles at Georgia Tech, City College of New York, and Texas A&M University. Education: B.S. in Chemical Engineering (University of Alabama, 2001), Ph.D. in Bioengineering (Rice University, 2006), Postdoctoral Research (University of Washington, 2006–2007). Research interests include biomaterials synthesis, targeted drug delivery systems, and polymer characterization, with a focus on cardiovascular tissue engineering and regenerative medicine. Her work bridges polymer chemistry and biomedical applications, aiming to develop materials that modulate cellular behavior for therapeutic purposes. Publications span biomaterials design, hydrogel platforms for disease modeling, and computational models of microvascular dynamics. Her recent work emphasizes fibrosis treatment and angiogenesis modulation through engineered materials. Contributions include developing nitric oxide-releasing polymers for vascular healing and peptide-functionalized biomaterials for targeted therapies. She collaborates on interdisciplinary projects, including vascular nanomedicine and decellularized matrix engineering for clinical translation.

Barbara Müllerمشاهده پروفایل

استاد مدعو

• Retrovirology
• HIV-1 Assembly and Maturation
• Viral Replication Mechanisms
• +۵ مورد دیگر

Barbara Müller is an Adjunct Professor at the Department of Virology , Heidelberg University, leading the Müller Lab at the Center for Integrative Infectious Disease Research (CIID) . Her research focuses on HIV-1 assembly, maturation, and post-entry mechanisms , using advanced imaging techniques such as super-resolution microscopy and fluorescence labeling. She also contributed to pandemic response efforts through SARS-CoV-2 antibody assays and epidemiological studies. Research interests include retroviral dynamics , viral capsid structure-function relationships , and host-cell interactions during HIV replication . Key projects investigate HIV-1 proteolytic maturation, capsid uncoating, and nuclear import. Her lab pioneered fluorescently labeled HIV derivatives to track viral processes in real-time. Recent work includes studies on HIV-1 spacer peptide 2 (SP2) in maturation, SARS-CoV-2 transmission in households, and post-acute sequelae of COVID-19. Collaborations with bioinformaticians and clinicians expanded her team’s capabilities in multiplex serology and population-based studies . Advising includes PhD students and postdocs in virology and immunology. The Müller Lab is part of CIID’s interdisciplinary environment, emphasizing translational research in infectious diseases.

Frans Bianchiمشاهده پروفایل

استادیار

• Membrane Proteins
• Lipid Antigens
• T Cell Activation
• +۴ مورد دیگر

Frans Bianchi is an Assistant Professor at the University of Groningen's Faculty of Science and Engineering, affiliated with the Molecular Immunology group within the Groningen Biomolecular Sciences and Biotechnology Institute (GBB). His research focuses on membrane proteins and lipids as antigens in T cell activation and their application in vaccination strategies. Bianchi holds a PhD in Membrane Enzymology from the University of Groningen (2016) and advanced degrees in Molecular Biology and Chemistry. Research Interests: Antigen presentation mechanisms T cell receptor interactions with MHC complexes Role of lipids in immune responses Development of immunotherapeutic agents Short-chain fatty acid effects on immune cells Recent Research Themes: Recent publications highlight work on antigen processing dynamics, macrophage inflammatory responses, and diagnostic methods for cell proliferation. Notable findings include butyrate's dual inflammatory effects and novel insights into CD36 receptor function in cancer biology. His teams explore both basic immunological mechanisms and translational applications. Awards & Grants: Recipient of NWO-VENI, ZonMW Off-Road grants, and Comenius Teaching Fellowships. Collaborates on NWO Demonstrator projects for cancer cell detection technologies. Labs & Teams: Leads the Molecular Immunology group focusing on immune cell signaling and vaccine development. Collaborates with multidisciplinary teams including organic chemists and biomedical engineers.

Thomas Lecuitمشاهده پروفایل

استاد

• Morphogenesis
• Developmental Biology
• Cell Biology
• +۳ مورد دیگر

Thomas Lecuit is a Professor at the Collège de France (holding the 'Dynamics of Living Systems' chair) and head of the 'Organization and Dynamics of Biological Forms' team at the Institut de Biologie du Développement de Marseille (IBDM, AMU/CNRS). He also directs the Turing Center for Living Systems (CENTURI), an interdisciplinary hub focused on biological complexity. A graduate of École Normale Supérieure, his research explores morphogenesis—the emergence of biological forms—using Drosophila as a model organism. His work integrates experimental and theoretical approaches to study cell behavior, mechanical forces, and geometric principles in development. Key achievements include the Liliane Bettencourt Prize for Life Sciences (2015), CNRS Silver Medal (2015), and election to prestigious academies (Académie des Sciences, Academia Europaea, EMBO). His current project, 'LivingOrigami,' investigates how geometry and mechanics govern tissue shape during morphogenesis. Supported by the France 2030 Initiative’s Chair of Excellence (2024), this work aims to bridge molecular biology with biophysics to understand form generation in health and disease. Research focuses on interdisciplinary methods, combining microscopy, genetic tools, and mathematical modeling. Key areas include actomyosin contractility, mechanochemical signaling, and the interplay between genetic and mechanical forces during embryogenesis.

Iris Yoonمشاهده پروفایل

استادیار

• Topological Data Analysis
• Algebraic Topology
• Network Theory
• +۵ مورد دیگر

Iris Yoon is an Assistant Professor of Mathematics at Wesleyan University, specializing in topological data analysis with applications in biological systems. Her research bridges algebraic topology, network theory, and machine learning to address complex problems in neuroscience, cancer research, and genomics. Her research interests focus on developing novel topological methods for analyzing biological data. She creates mathematical frameworks that extract meaningful patterns from high-dimensional datasets, particularly in tumor microenvironments and neural systems. Her work combines persistent homology, relational topology, and multiscale analysis to reveal hidden structures in biological systems. Yoon's publication record shows consistent contributions to computational topology with increasing biological applications since 2018. Her recent work (2023-2025) demonstrates sophisticated applications of topological methods to tumor-immune interactions, neural manifolds, and cellular spatial patterns, reflecting an evolving research trajectory toward complex biological systems. Outside traditional academic publications, Yoon has developed practical applications including a classical musician recommendation system based on collaboration networks using node2vec embeddings, and a COVID-19 hospital bed shortage prediction model. These demonstrate her commitment to applying topological methods to real-world data science problems.

Mary-Ellen Harperمشاهده پروفایل

استاد

• Mitochondrial Bioenergetics
• Metabolic Diseases
• Oxidative Phosphorylation
• +۳ مورد دیگر

Dr. Mary-Ellen Harper is a Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa Faculty of Medicine. She holds a Tier I Canada Research Chair in Mitochondrial Bioenergetics and Metabolic Health, and serves as Director of both the Ottawa Institute of Systems Biology and the NSERC-CREATE MATRIX program. Her research focuses on mitochondrial energy transduction mechanisms in health and disease. BSc, University of Guelph PhD, University of Ottawa Postdoctoral Fellowship, Cambridge University As a leading expert in mitochondrial bioenergetics, Dr. Harper investigates metabolic pathways affecting cellular energy efficiency through mitochondrial uncoupling proteins (UCPs), adenine nucleotide translocators (ANTs), and supercomplex formation. Her work has significant implications for obesity, diabetes, cardiovascular diseases, and neurodegenerative disorders. Dr. Harper's research team has produced over 215 peer-reviewed publications cited more than 21,300 times (H-index 74). Her recent publications explore mitochondrial transporter networks in cancer, cardiac metabolic regulation, and exercise interventions for obesity-related metabolic dysfunction. Scientific Distinctions Tier I Canada Research Chair (2024-2031) Lifetime Achievement Award, Diabetes Canada (2021) University Research Chair in Mitochondrial Bioenergetics (2016-2021, 2021-2024) Premier's Research Excellence Award (2000) John Charles Polanyi Prize (1995) Dr. Harper has supervised 21 MSc, 9 PhD, and 11 postdoctoral fellows. Her lab receives funding from CIHR, NSERC, Canadian Nuclear Laboratories, and the Canada Research Chairs program. The Harper Laboratory operates from Roger Guindon Hall, Room 3522, at the University of Ottawa.

Carsten Wernerمشاهده پروفایل

استاد

• Biomaterials
• Polymer Science
• Tissue Engineering
• +۳ مورد دیگر

Carsten Werner is a Professor for Biofunctional Polymer Materials at the Technical University of Dresden , affiliated with the Center for Regenerative Therapies Dresden and the Department of Chemistry and Food Chemistry . He serves as the head of the Institute Biofunctional Polymer Materials within the Max Bergmann Center of Biomaterials.

Cagla Erogluمشاهده پروفایل

استاد

• Neuroscience
• Neurobiology
• Astrocyte Biology
• +۵ مورد دیگر

Cagla Eroglu is a Professor of Cell Biology and Neurobiology at Duke University , where she holds the Duke Health Distinguished Professorship . She is affiliated with the Duke Institute for Brain Sciences , Duke Regeneration Center , and Duke Initiative for Science & Society . Research Focus: Her work explores how astrocytes regulate synaptogenesis and neural circuit function in health and disease. Key areas include: Astrocyte development and morphogenesis Synapse formation and plasticity Neurodevelopmental disorders (e.g., autism, Huntington’s disease) Neurodegenerative mechanisms (e.g., Parkinson’s disease) Recent Publications highlight tools like GEARBOCS for astrocyte gene editing, SynBot for synapse quantification, and mechanistic studies on thrombospondin-α2δ-1 and ATP13A4 pathways. She was elected to the American Academy of Arts and Sciences (2024) and recognized as an HHMI Investigator (2021) . Grants include leadership in the NIH BRAIN Initiative U19 Program and multidisciplinary funding from NINDS and NIMH . Her lab fosters collaboration, innovation, and mentorship, with a focus on translating glial biology to therapeutic strategies.

Ana Tadijanمشاهده پروفایل

پژوهشگر

• Cancer Biology
• Molecular Oncology
• Integrin Signalling
• +۴ مورد دیگر

Dr. Ana Tadijan is a research associate at the Ruđer Bošković Institute (Division of Molecular Biology, Laboratory for Molecular and Cellular Biology) in Zagreb, Croatia, where she investigates the molecular mechanisms governing cancer progression, drug resistance, and cell adhesion. Education & Academic Standing: PhD-level researcher (Research Associate) continuously active at RBI since at least 2012. Supervises graduate theses and mentors MSc/PhD students (e.g., Doris Stepić, Kristina Čuljak, Christine Supina, Ana Dekanić). Research Interests: Her work integrates cancer cell biology , integrin-mediated adhesion , mitochondrial metabolism , p53-family signalling , and targeted therapy resistance in melanoma and breast cancer models. Additional focus lies on neuroprotective signalling of cannabinoids and nanoparticle toxicology. Publication Profile: Since 2012 she has co-authored >40 peer-reviewed papers and conference abstracts. Recent output (2021-2024) centres on: Mechanisms of vemurafenib and BRAF-inhibitor resistance in melanoma. Role of mitochondrial NME6 and Sirt3 in tumour metabolism. Integrin α6β4 and αV-containing adhesomes driving adhesion and drug sensitivity. p53-family splice isoforms as modulators of melanoma aggressiveness. Scientific Awards & Funding: While no specific prizes are mentioned, she is a recurring presenter at the International p53 Workshop, FEBS, EACR, and national Croatian cancer-research meetings, indicating sustained competitive funding and recognition. Laboratory & Collaborations: She conducts research within the RBI Laboratory for Molecular and Cellular Biology, collaborating extensively with groups led by Maja Herak Bosnar, Neda Slade, Andreja Ambriović-Ristov, Martin Humphries (UK), and international partners on adhesome proteomics and melanoma resistance projects.