جست‌وجوی استاد و پژوهشگر

• Gynecologic Oncology
• Cancer Immunotherapy
• Tumor Immunology
• +۷ مورد دیگر

Dr. Alessandro D. Santin is a Professor at the Yale School of Medicine within the Department of Obstetrics, Gynecology & Reproductive Sciences . He serves as Clinical Research Team Leader for Gynecologic Oncology at the Yale Cancer Center and co-chief of the Section of Gynecologic Oncology. Graduated magna cum laude from the University of Brescia, Italy Completed fellowships at the University of California, Irvine and University of Arkansas for Medical Sciences Dr. Santin's research bridges tumor immunology and translational oncology, focusing on: Immunotherapy for chemotherapy-resistant gynecologic cancers Therapeutic HPV vaccines for genital tumors Monoclonal antibody development Angiogenesis and radiation biology His recent publications highlight advancements in: VEGF/VEGFR2 system targeting for ovarian cancer Personalized medicine approaches with biomarkers Microsatellite instability in endometrial cancer immunotherapy Antibody-drug conjugates for uterine serous carcinoma NAC supplementation in post-COVID gynecologic patients Scientific Awards: American Association young investigator award Italian Society of Gynecologic Oncologists award for translational science Dr. Santin's lab (Laboratory for Surgery, Obstetrics & Gynecology) at Yale collaborates extensively, with 50+ postdoctoral fellows mentored. Current grants include NIH funding for Clostridium Perfringens Enterotoxin as a novel ovarian cancer therapy and leadership in multiple Gynecologic Oncology Group trials.

• Environmental Epidemiology
• Children's Environmental Health
• Molecular Epidemiology
• +۳ مورد دیگر

Margaret Karagas, PhD is the inaugural Department Chair and James W. Squires Professor of Epidemiology at the Geisel School of Medicine at Dartmouth College, with a secondary appointment as Professor of Community and Family Medicine. She also serves as Director of both the Children's Environmental Health and Disease Prevention Research Center and the Center for Molecular Epidemiology at Dartmouth. Her leadership extends to the NIH-funded Environmental Influences on Child Health Outcomes (ECHO) Program, which encompasses over 90,000 participants across the United States. Dr. Karagas earned her PhD from the University of Washington in 1990 and has established herself as a leading researcher in environmental epidemiology. She collaboratively developed an innovative cross-disciplinary postdoctoral and graduate program in Quantitative Biomedical Sciences (QBS) that integrates epidemiology, bioinformatics, and bistatistics. Her research focuses on interdisciplinary studies investigating environmental exposures, host factors, and biological mechanisms affecting health from infancy through adulthood, with particular emphasis on under-studied rural populations. Dr. Karagas employs high-dimensional analytic tools along with biomarkers and sensors to study the exposome, genetic susceptibility, and biological response. Her work has uncovered adverse cardiometabolic, neurodevelopmental, and immune-related health outcomes associated with drinking water contaminants, food-borne toxicants (including in infant first foods), and exposures from woodstoves. Analysis of her recent publications reveals a strong focus on environmental health impacts across the lifespan, with significant contributions to understanding how environmental exposures affect child development, chronic disease risk, and health disparities. Her work frequently employs advanced molecular and analytical techniques to assess environmental exposures and their biological consequences. Dr. Karagas serves on numerous prestigious international consensus panels and committees, including those for the United Nations, World Health Organization, International Agency for Research on Cancer, European Food Safety Authority, US National Institutes of Health, and National Academies of Science, Engineering and Medicine. As an academic leader, she has mentored diverse investigators at all career stages and established innovative training programs. Her research has directly contributed to practice and policy changes regarding environmental health threats. She maintains active collaborations across multiple centers at Dartmouth including the Dartmouth Toxic Metals Superfund Research Program and Dartmouth SYNERGY.

Florent Ginhouxمشاهده پروفایل

دانشیار مدعو

• Immunology
• Innate Immunity
• Dendritic Cell Biology
• +۳ مورد دیگر

Florent Ginhoux serves as a Senior Principal Investigator at the Singapore Immunology Network (SIgN), A*STAR, and holds adjunct associate professor positions across Singapore's academic landscape including the Yong Loo Lin School of Medicine at National University of Singapore, Duke-NUS Medical School, Skin Research Institute of Singapore, and Nanyang Technological University's School of Biological Sciences, with additional affiliation at Shanghai Immunology Institute. His academic foundation was established in France: Biochemistry degree from University Pierre et Marie Curie (UPMC), Paris VI Masters in Immunology from Pasteur Institute (2000) PhD from UPMC, Paris VI (2004) Following postdoctoral training at Mount Sinai School of Medicine under Dr. Miriam Merad, he joined SIgN in 2009 after serving as Assistant Professor at Mount Sinai. His laboratory pioneers research on dendritic cell and macrophage ontogeny using high-dimensional platforms including RNA sequencing, single-cell transcriptomics, and mass cytometry (CyTOF) to define cell populations by developmental origin and uncover their specialized immune functions. Recognized as an EMBO Young Investigator, his work bridges fundamental immunology with therapeutic applications for immune pathologies. His mentoring includes PhD student Katharine YANG and postdoctoral researchers Satish Tiwari, Sulvania Susanto, Priya Dhami, and William Ho. The lab actively collaborates on immunomonitoring projects leveraging SIgN's advanced platforms for high-dimensional immune profiling in both human and murine systems.

• Genomic Instability
• DNA Replication and Repair
• Computational Biology
• +۵ مورد دیگر

Dr Michael Boemo is an Assistant Professor at the University of Cambridge, holding dual appointments in the Department of Pathology and Department of Genetics. He leads research at the intersection of computational biology, DNA replication, and cancer genomics, developing machine learning tools to analyze replication stress and genomic instability. Academic Background: BA in Mathematics (Rutgers University), PhD in Physics (University of Oxford) Research Focus: Genomic instability in cancer, DNA replication/repair defects, computational modeling using machine learning and high-performance simulations Teaching: Lectures in Natural Sciences Tripos (mathematical biology, genetics, systems biology), module organizer for cancer biology and biological modeling His research group leverages nanopore sequencing and AI to map replication fork dynamics, revealing how stalled forks generate mutations in cancer cells and pathogens. Recent work examines extrachromosomal DNA replication vulnerabilities and transcription-replication conflicts. Dr Boemo collaborates across computational biology and cancer research domains, with publications spanning journals like Nature Methods, Cell, and PLoS Computational Biology. His lab develops tools such as DNAscent for replication fork analysis and explores therapeutic targeting of replication stress.

• Autism Genetics
• Genetic Architecture
• Copy Number Variants
• +۵ مورد دیگر

Lauren Weiss, PhD is a Professor of Psychiatry at the University of California, San Francisco (UCSF) School of Medicine and a faculty member at the UCSF Weill Institute for Neurosciences. Her research focuses on understanding the genetic architecture of autism spectrum disorder through genome-wide genetic data analysis and human induced pluripotent stem cell (iPSC) models. Dr. Weiss's laboratory investigates the genetic mechanisms by which DNA variants influence autism risk, examining questions about copy number vs. SNP variation, rare vs. common variation, gene-sex interaction, gene-gene interaction, and gene-environment interaction. Her team uses rich genetic datasets to identify susceptibility loci and the physiological pathways these risk loci implicate. Additionally, they employ iPSC models to study known mutations or copy number variants predisposing to autism, first identifying the effects of genetic risk variants and then determining whether these effects can be modified at the cellular level by environmental or pharmacological agents. Analysis of Dr. Weiss's recent publications reveals a strong focus on sex differences in autism genetics, the role of specific copy number variants (particularly 16p11.2 and 22q11.2), maternal environmental factors during pregnancy, and the integration of multi-omics data to understand neurodevelopmental pathways. Her work bridges basic genetic research with potential clinical applications for improving understanding, prevention, diagnosis, and treatment of autism and related traits. Dr. Weiss has secured significant research funding as Principal Investigator on multiple NIH grants, including R01MH114924 (Decoding the Genetics of Sexual Dimorphism in Autism Spectrum Disorders), R01MH107467 (Utilizing eQTL networks to gain biological insight into multigenic CNVs), and DP2OD007449 (Dissecting Epistasis and Pleiotropy in Autism towards Personalized Medicine). Her laboratory offers research opportunities for students interested in analytical genetics projects related to gene-environment effects, gene-sex effects, gene-gene effects, and the relationship between ASD and brain size. Dr. Weiss actively collaborates with numerous researchers across institutions, particularly on large-scale genomic studies of autism and other neurodevelopmental disorders. Her work has contributed significantly to our understanding of the complex genetic architecture underlying autism spectrum disorder and related conditions.

Mandi de Mestreمشاهده پروفایل

استاد

• Reproductive Biology
• Placental Development
• Equine Medicine
• +۵ مورد دیگر

Dr. Mandi de Mestre is a Professor in the Department of Biomedical Sciences at Cornell University's College of Veterinary Medicine. As Director of the Baker Institute for Animal Health and holder of the Dorothy Havemeyer McConville Professorship of Equine Medicine, her research focuses on equine pregnancy biology, placental development, and fetal health. Director, Baker Institute for Animal Health Dorothy Havemeyer McConville Professor of Equine Medicine Affiliated with Cornell's College of Veterinary Medicine Her laboratory investigates: Molecular mechanisms of placental development Genetic causes of early pregnancy loss Congenital musculoskeletal disorders in Thoroughbreds Non-invasive diagnostics for fetal health Comparative studies linking equine and human pregnancy pathologies Recent research trends show strong emphasis on genomic stability, immune interactions during implantation, and epidemiological factors affecting equine pregnancies. Collaborations with institutions like the University of Nottingham and Royal Veterinary College UK highlight her interdisciplinary approach. The Equine Pregnancy Laboratory employs molecular biology, immunology, and genetics to address critical gaps in placental biology, with implications for both veterinary and human medicine.

• Neuroscience
• Developmental Biology
• Molecular Biology
• +۳ مورد دیگر

Carina Hanashima is a Professor at the Faculty of Education and Integrated Arts and Sciences , Waseda University, Japan. Her research focuses on neuroscience , developmental biology , and molecular mechanisms underlying cortical development . She has held academic positions at Kobe University (2014.04-2018.03), RIKEN (2008.10-2017.03), Osaka University (2012.04-2015.03), and Nara Women's University (2007.09-2014.11). Research Interests Neuronal specification and cortical circuit formation Role of transcription factors (e.g., Foxg1, Robo1) in brain development Gene regulatory networks in neurogenesis Evolutionary origins of the neocortex Recent Trends in Publications : Her work explores transcriptional repression , axon guidance signaling , and developmental clock mechanisms in mammalian and non-mammalian models (chicks, mice). Key themes include neurodevelopmental disorders (e.g., autism, schizophrenia), angiogenesis , and cell migration . Scientific Awards : Poster Award, Asia-Pacific Developmental Biology Conference APDBC (2012.10) Grants and Projects : Japan Society for the Promotion of Science Grants-in-Aid (2016.06-2021.03, 2021.04-2022.03) RIKEN Joint Retreat Organizer (2011-2017) Labs and Collaborations : She leads the Hanashima Lab at Waseda University, focusing on spatiotemporal control in neuronal identity and neurovascular coupling . Her lab employs genetic lineage tracing , in situ hybridization , and in utero electroporation techniques.

Lin Hanمشاهده پروفایل

استاد

• Nanobiomechanics
• Biomaterials
• Tissue Engineering
• +۳ مورد دیگر

Professor Lin Han is affiliated with the School of Biomedical Engineering, Science and Health Systems at Drexel University . His research focuses on nanoscale structure-property relationships of biomaterials , with applications in disease diagnostics, tissue regeneration, and bio-inspired material design . He leads the Nanobiomechanics Laboratory , integrating nanotechnology, biomechanics, and gene therapy. Education: PhD in Bio- and Polymeric Materials, Massachusetts Institute of Technology (2007) BE in Materials Engineering, Tsinghua University (2002) His research interests include: Nanoscale biomechanics of extracellular matrix (ECM) biomolecules like aggrecan, decorin, and type V collagen . Understanding genetic origins of joint tissue diseases and mechanotransduction in cartilage. Developing stimulus-responsive biomaterials and ECM-inspired tissue engineering strategies. The scientific awards he has received include: 2024 AIMBE College of Fellows 2024 NIH Grant for cartilage PCM mechanotransduction 2022 Drexel Faculty Award 2021 Kappa Delta Young Investigator Award 2016 Commonwealth CURE Program Grant His research on articles demonstrates trends in ECM nanomechanics , collagen structure-function analysis , and osteoarthritis intervention using advanced imaging and molecular engineering. His work bridges biomaterial design and clinical applications for cartilage repair. He has secured significant grants and collaborates on interdisciplinary projects involving MIT, Drexel, and industry partners . His lab develops novel hydrogels and nanoscale testing methods to study tissue degeneration and regeneration.

Kristine Beate Walhovdمشاهده پروفایل

استاد

• Cognitive Neuroscience
• Neuropsychology
• Brain Aging
• +۵ مورد دیگر

Kristine Beate Walhovd is a Professor at the Department of Psychology , University of Oslo, and co-leader of the Center for Lifespan Changes in Brain and Cognition (LCBC) . She is affiliated with the UiO:Life Science initiative and has led major projects like Lifebrain (€2.5M) and Neurocognitive Plasticity (ERC Starting Grant, €1.5M). Current roles: Professor (since 2016), Co-leader of LCBC Key affiliations: University of Oslo, Lifebrain Consortium, UiO:Life Science Her research focuses on lifespan brain and cognitive changes , examining both positive/negative developmental trajectories from age 4 to 90. She studies interactions between biomedical risks (e.g., Alzheimer's, fetal drug exposure) and cognitive outcomes, employing MRI , DTI , and ERP methodologies. Recent publications highlight work on Alzheimer's biomarkers , sleep-brain interactions , memory consolidation , and fetal brain influences . Her 2025 papers in Scientific Reports and Neurobiology of Aging examine hippocampal stability and brain network segregation. Awards include: 2015 University of Oslo Research Prize (shared with Anders Fjell) 2011 Member, Norwegian Academy of Sciences and Letters 2006 His Majesty the King's Gold Medal for best doctoral thesis She supervises doctoral candidates and teaches cognitive neuroscience , experimental methods , and thesis writing .

Maureen Sartorمشاهده پروفایل

استاد

• Epigenetics
• Bioinformatics
• Cancer Research
• +۷ مورد دیگر

Maureen Sartor is a Professor in the Department of Computational Medicine and Bioinformatics at the University of Michigan Medical School. Her work bridges computational biology, epigenetics, and cancer research, with recent contributions to understanding environmental toxicant impacts on DNA methylation, HPV-associated head and neck cancers, and neurodegenerative disease mechanisms. Key research themes: Epigenetic regulation, bioinformatics modeling, environmental health Active clinical trial collaborations in immunotherapy rechallenge and neoadjuvant treatment strategies Leadership in cross-species toxicoepigenetic studies and microbiome-immune crosstalk in oral cancer Recent publications highlight her expertise in: Epigenetic age acceleration in ALS and its environmental correlates HPV integration mechanisms in oropharyngeal cancer Chemical oxidation techniques for piRNA discovery Sex-specific epigenetic responses to lead and phthalate exposure Her interdisciplinary approach connects computational methods with experimental validation across multiple disease models.

Ellen Rothenbergمشاهده پروفایل

استاد

• Cellular and Developmental Biology
• Molecular Biology
• Immunology
• +۳ مورد دیگر

Ellen Rothenberg is the Edward B. Lewis Professor of Biology at the California Institute of Technology (Caltech). She earned her A.B. in Biochemical Sciences from Harvard University (1972) and a Ph.D. in Molecular Biology from MIT (1977). Her academic career at Caltech spans roles from Assistant Professor (1982–88) to her current position. She holds the Ruddock Professorship (2007–21), Distinguished Professor (2021–), and Lewis Professor (2021–). Her research focuses on transcriptional networks governing T-cell development and signaling, particularly how hematopoietic stem cells commit to T-lymphocyte lineages. Using in vitro systems, molecular genetics, and genomic approaches, her lab explores transcription factor interactions, chromatin dynamics, and signaling pathways that drive T-cell identity. Key interests include understanding stem-cell multipotentiality loss, irreversible commitment mechanisms, and links to autoimmune predisposition. Rothenberg is an Andrew D. White Professor-at-Large at Cornell University (2021–2027), collaborating with immunology and molecular biology departments. She has organized international conferences, served on NIH review panels, and advises biotech firms like Century Therapeutics. Her honors include membership in the National Academy of Sciences, AAAS and American Academy of Arts and Sciences fellowships, and the Feynman Teaching Prize (2016). Education: A.B., Harvard University, Biochemical Sciences, 1972 Ph.D., Massachusetts Institute of Technology, Molecular Biology, 1977 Awards: AAAS Fellow, American Academy of Arts and Sciences Fellow Member, National Academy of Sciences American Association of Immunologists Distinguished Fellow Richard P. Feynman Prize for Excellence in Teaching (2016) External Roles: Cornell’s ADW-PAL (2021–2027), collaborating with faculty hosts Brian Rudd and Andrew Grimson Scientific Advisor, Century Therapeutics, A2 Biotherapeutics, Kite Pharma Her work bridges basic research and clinical applications, including immunogenomics symposia and public lectures on T-cell programming. Ongoing projects explore evolutionary origins of lymphocyte development through comparative analysis of basal vertebrates.

• Diabetic Nephropathy
• Chronic Kidney Disease
• Maternal and Fetal Health
• +۳ مورد دیگر

Carol Pollock is a Professor at the University of Sydney's Northern Clinical School , affiliated with the Kolling Institute of Medical Research . Her research focuses on diabetic kidney disease, chronic kidney disease (CKD) management, and maternal-fetal programming of renal health. Thematic areas: Obesity, Diabetes, Cardiovascular Disease , Healthy Ageing , and Lifespan Methodological approaches: Animal models , Cellular/molecular studies , and Translational research Clinical specialty: Nephrology Her work explores epigenetic mechanisms in maternal obesity-related kidney disease, SGLT2 inhibitors for cardiorenal protection, and novel biomarkers like urinary exosomes and volatile organic compounds. Recent studies emphasize intergenerational metabolic programming and renoprotective drug development . Key publication trends (2023-2025) include: Diabetic nephropathy (2025: SGLT2 inhibitors, YAP1 pathways) CKD progression (2024: DISCOVER cohort, hyperkalemia management) Maternal environmental impacts (2025: PM2.5 exposure, fetal kidney health) Renal fibrosis (2023: i-body AD-214, CXCR4 blockade) Translational nephrology (2024: urinary cell imaging, exosome therapy) Global CKD guidelines (2024: Asia-specific management frameworks) Her team mentors PhD students Daisy Chen, Wenyang Shi, and Chi Tran, investigating stem cell therapies and renal regeneration in diabetic and acute kidney injury models.

David Weisblatمشاهده پروفایل

استاد

• Developmental Biology
• Evolutionary Developmental Biology (Evo-Devo)
• Molecular Phylogenetics
• +۴ مورد دیگر

David Weisblat is a Professor in the Department of Molecular and Cell Biology at UC Berkeley's College of Letters & Science. His research focuses on developmental and evolutionary processes in glossiphoniid leeches (e.g., Helobdella ), particularly their segmentation mechanisms and molecular phylogeny within Lophotrochozoa. He leads studies integrating embryological, genomic, and genetic approaches to understand how developmental pathways evolved across bilaterian animals. Research Interests: Weisblat’s work addresses how cell fates and signaling pathways (WNT, NOTCH, TGFβ) shape leech development, with emphasis on the evolutionary origins of segmentation. His lab combines microinjection techniques, transcriptome analysis, and CRISPR mutagenesis to explore stem cell dynamics and conserved developmental programs. Key Projects: Current efforts investigate grandparental stem cell divisions in segmentation and intercellular signaling during early embryogenesis. The lab’s genomic resources—including BAC libraries and EST databases—facilitate comparative studies across Lophotrochozoan taxa. Lab Contributions: The Weisblat lab pioneered Helobdella as a model organism, enabling breakthroughs in Evo-Devo. Their findings bridge developmental plasticity and evolutionary innovation, particularly in annelids versus arthropods/deuterostomes.

Maja Adamskaمشاهده پروفایل

دانشیار

• Evolutionary Biology
• Developmental Biology
• Comparative Genomics
• +۷ مورد دیگر

Maja Adamska is an Associate Professor and ARC Future Fellow at the Australian National University (ANU) in the Research School of Biology. She serves as Associate Director of Education and Head of the Biology Teaching and Learning Centre. Her primary research affiliation is with the Division of Biomedical Science and Biochemistry, where she leads the Adamska Group focused on the genomic and evolutionary basis of animal development. She is based in Room 2.022, Level 2, Linnaeus Building at ANU. Dr. Adamska studied biology with a focus on embryology and evolutionary biology at Jagiellonian University in Krakow, Poland. She completed her PhD in Germany working with Eva Bober and Thomas Braun on homeobox genes in inner ear development using vertebrate models from medaka fish to mice. Her postdoctoral work included research at the University of Michigan in Miriam Meisler's laboratory studying mouse mutants for limb patterning, followed by work at the University of Queensland with Bernie Degnan analyzing developmental signaling pathways in the sponge Amphimedon queenslandica. She was a group leader at the Sars International Centre for Marine Molecular Biology in Bergen, Norway from 2007-2015 before joining ANU in 2015. Her research addresses fundamental biological questions about how complex animals develop from single cells and how the first multicellular animals evolved from single-cell ancestors. She uses calcareous sponges to investigate the evolutionary origins of key developmental processes including germ layer segregation and axial patterning. Her work spans multiple areas including evolutionary developmental biology, comparative genomics, and the study of major transitions in animal evolution such as the emergence of multicellularity and morphological complexity. Her research has revealed surprising similarities between sponge and higher animal embryonic development, challenging traditional views of animal evolution. Analysis of Dr. Adamska's recent publications shows a strong focus on sponge and coral biology, with increasing attention to conservation and sustainability issues related to marine ecosystems. Her work combines molecular, genomic, and evolutionary approaches to understand fundamental biological processes, with particular emphasis on gene regulatory networks, developmental signaling pathways, and the genomic basis of morphological complexity in early-branching animals. ARC Future Fellow (since 2017) h-index of 32 with 3,990 citations according to Scopus Multiple research grants including ARC Centre of Excellence for Integrated Coral Reef Studies (2014-2021) Dr. Adamska supervises research on multiple projects including coral regeneration, molecular mechanisms of developmental signaling pathways in sponges, identification of target genes for developmental transcription factors, skeleton formation in corals and sponges, and sponge and coral microbiomes. She also serves as Convenor for BIOL2174 and has developed innovative educational approaches including the Digital Marine platform for blended learning in marine biology. Her research group, the Adamska Group, focuses on the genomic and evolutionary basis of animal development, using calcareous sponges as model organisms to gain insights into the evolutionary origins of complex developmental processes. The group collaborates with international researchers across multiple institutions to advance understanding of early animal evolution and development.

Torsten Nielsenمشاهده پروفایل

استاد

• Sarcoma
• Breast Cancer
• Molecular Diagnostics
• +۷ مورد دیگر

Professor Torsten Nielsen is a clinician-scientist at the University of British Columbia 's Department of Pathology & Laboratory Medicine (Faculty of Medicine), based at Vancouver General Hospital and BC Cancer . He directs UBC's MD/PhD Program , contributes to cancer clinical trials with the Canadian Cancer Trials Group , and chairs the international Connective Tissue Oncology Society 's Research Committee. Key affiliations: UBC, Vancouver General Hospital, BC Cancer, Molecular and Advanced Pathology Core Academic focus: Translational research in sarcomas and breast cancer His research prioritizes translating genomic discoveries into clinical diagnostics and treatments, particularly for synovial sarcoma , breast cancer subtypes , and tenosynovial giant cell tumors . He develops FDA-cleared molecular assays like the PAM50 (Prosigna) test and leads pan-Canadian precision oncology initiatives . Collaborative efforts include work with Stanford, Leiden, and DKFZ Heidelberg. Recent publications highlight advancements in epigenetic therapies , immune biomarker validation , and synovial sarcoma pathogenesis . His lab's work on CSF1/CSF1R signaling inspired new treatment strategies for joint-destructive tumors. Scientific Awards: Fellow, Canadian Academy of Health Sciences Fellow, Royal Society of Canada As director of UBC's MD/PhD Program, he trains future clinician-scientists. His lab team includes experts in epigenomics , proteomics , and mouse modeling . Current projects focus on precision oncology for sarcomas and Ki67 standardization in breast cancer.