جستجوی استاد راهنمای دانشگاهی

Barbara L. Hempsteadمشاهده پروفایل

استاد

• Neuroscience
• Neurotrophin Signaling
• Neurodegenerative Diseases
• +۵ مورد دیگر

Dr. Barbara L. Hempstead is a Professor of Neuroscience and Medicine at Weill Cornell Medical College, where she has held positions since 2001 and 2002 respectively. Her research focuses on neurotrophin signaling mechanisms, particularly the roles of BDNF and its receptors in neuroinflammation, synaptic plasticity, and neurodegenerative diseases. She has made significant contributions to understanding proBDNF/proNGF signaling pathways in neuronal apoptosis and vascular biology. Education: M.D., Ph.D., Washington University School of Medicine (1982) B.A., Tufts University (1976) Dr. Hempstead's work bridges molecular neuroscience and cardiovascular biology, with a particular interest in receptor stoichiometry (p75NTR, TrkB), neurotrophin-induced synaptic remodeling, and therapeutic applications of neurotrophin modulators in Huntington's disease and post-seizure neuronal injury. Her lab investigates how genetic variants like BDNF Val66Met influence anxiety-related behaviors, social memory, and neurodegenerative disease progression through altered neurotrophin trafficking and signaling. Her recent publications highlight neuroinflammatory mechanisms (2023), immune-neurotrophin interactions (2022), and molecular pathways involving BDNF prodomain structure (2020) and SorCS2-mediated receptor trafficking (2017-2020). While no scientific awards are explicitly mentioned in the scraped text, her funded research (National Institute on Aging, NIMH) demonstrates sustained recognition of her work in neurotrophin biology. Dr. Hempstead's lab develops in vitro and in vivo models to study neurotrophin-receptor dynamics, including 3D culture systems for angiogenesis research and transgenic mouse models for Huntington's disease. Her interdisciplinary approach combines molecular neurobiology with vascular physiology to uncover novel therapeutic targets for neurological and cardiovascular conditions.

• Systems Biology
• Cancer Research
• Drug Resistance
• +۷ مورد دیگر

Sampsa Hautaniemi is a Professor at the Department of Biochemistry and Developmental Biology within the Faculty of Medicine at the University of Helsinki. He serves as Principal Investigator of the Systems Biology of Drug Resistance in Cancer research group and holds docentship in the Faculty of Medicine. Professor Hautaniemi actively supervises doctoral students across multiple programs including the Doctoral Programme in Biomedicine, Doctoral Programme in Clinical Research, and Doctoral Programme in Integrative Life Science. His research focuses on systems biology approaches to understand drug resistance mechanisms in cancer, particularly ovarian cancer. His work integrates computational biology, genomics, epigenetics, and bioinformatics to develop precision medicine approaches for cancer treatment. His laboratory develops innovative computational methods and experimental models including patient-derived organoids to study tumor evolution, identify therapeutic targets, and predict treatment responses. Analysis of his recent publications reveals a strong emphasis on understanding tumor heterogeneity, clonal evolution during therapy, and the development of computational tools for cancer genomics. His work spans multiple disciplines including cancer biology, computational biology, immunology, and precision medicine, with a particular focus on high-grade serous ovarian cancer as a model system. Scientific Awards: The Anders Jahre Medical Prize to young medical scientists (2014) for outstanding research on systems biology and cancer The Finnish Medical Foundation 50-years jubileum award (2010) Professor Hautaniemi has supervised numerous doctoral students and early-career researchers, contributing significantly to cancer research education. His research is supported by multiple active projects including the DECIDER project (Clinical Decision via Integrating Multiple Data Levels to Overcome Chemotherapy Resistance in High-Grade Serous Ovarian Cancer) funded until 2026, as well as projects from the Academy of Finland, Cancer Foundation, and industry partners like Orion Corporation. His laboratory maintains a patient-derived organoid biobank for high-grade serous ovarian cancer and develops computational tools like Jellyfish for visualizing tumor evolution.

Peter J. Thomasمشاهده پروفایل

استاد

• Systems Neuroscience
• Computational Neuroscience
• Theoretical Biophysics
• +۷ مورد دیگر

Peter J. Thomas is a Professor in the Department of Mathematics, Applied Mathematics, and Statistics at Case Western Reserve University's College of Arts and Sciences, with secondary appointments in Electrical Engineering and Computer Science, Cognitive Science, and Biology. He serves as Co-Editor-in-Chief of Biological Cybernetics and leads the Computational Biomathematics Laboratory. Primary Affiliation: Department of Mathematics, Applied Mathematics, and Statistics Secondary Affiliations: Department of Electrical Engineering and Computer Science, Department of Cognitive Science, Department of Biology Leadership: Co-Editor-in-Chief of Biological Cybernetics Thomas earned his B.A. in Physics and Philosophy from Yale University (1990), M.S. in Mathematics from the University of Chicago (1994), and both M.A. in Conceptual Foundations of Science and Ph.D. in Mathematics from the University of Chicago (2000). His research spans mathematical neuroscience, theoretical biophysics, and information theory applications to biological systems. Thomas specializes in understanding how noise and stochasticity affect neural coding, developing mathematical frameworks for gradient sensing in cells, and applying graph theory to biological networks. His work on stochastic shielding has provided novel approaches to simplifying complex stochastic models while preserving essential dynamics. His research bridges theoretical mathematics with experimental neuroscience through collaborations with the Chiel laboratory and others. Thomas's recent publications demonstrate a strong focus on stochastic oscillators, sensory feedback mechanisms, and information theory applications to biological systems. His work consistently develops novel mathematical frameworks to address specific biological questions, with significant contributions to understanding phase dynamics in neural oscillators and information processing in biochemical signaling. Core Fulbright Scholar Program (2013) Simons Fellow in Mathematics Program (2014) Multiple NSF grants as Principal Investigator Co-Editor-in-Chief of Biological Cybernetics Thomas has mentored numerous students at all levels, from undergraduates to postdoctoral researchers. His laboratory has produced successful scholars who have gone on to faculty positions at institutions like New Jersey Institute of Technology and the University of Nevada, Reno. He has actively organized workshops at the Banff International Research Station and served on editorial boards for leading journals in computational neuroscience. The Computational Biomathematics Laboratory focuses on developing mathematical frameworks to understand neural dynamics, cellular signaling, and pattern formation. The lab maintains strong collaborations with experimental neuroscience groups and has made significant contributions to understanding rhythmic neural systems, respiratory control mechanisms, and information processing in biological systems.

Ashley Mosemanمشاهده پروفایل

استادیار

• CNS immunity
• Olfactory barrier immunology
• Neuroimmunology
• +۵ مورد دیگر

Ashley Moseman serves as an Assistant Professor of Integrative Immunobiology and Assistant Professor of Cell Biology at Duke University School of Medicine. She holds significant affiliations as a Faculty Network Member of the Duke Institute for Brain Sciences and a Member of the Duke Cancer Institute. Her pioneering research examines the delicate balance between neuronal function and immune protection at the olfactory neuroepithelial barrier, where sensory neurons directly interface with the external environment while protecting the central nervous system from pathogens. Dr. Moseman completed her Ph.D. at Harvard University in 2011, establishing the foundation for her interdisciplinary career at the intersection of immunology and neuroscience. Her research program focuses on understanding how immunological surveillance operates at the unique olfactory barrier, where neurons must contact the external environment to perform chemosensory functions while preventing pathogens from entering the CNS. The Moseman Lab employs cutting-edge multiphoton intravital imaging to visualize immune responses in vivo, revealing dynamic cellular interactions during viral infections and responses to pathogens like Naegleria fowleri. Current projects investigate olfactory barrier mechanisms, neuroimmune crosstalk, host-pathogen dynamics, and immune responses to deadly neurotropic pathogens. Analysis of Dr. Moseman's publication record demonstrates a cohesive research trajectory centered on neuroimmunology and mucosal defense mechanisms. Her work spans fundamental immunological processes, host-pathogen interactions at neural interfaces, and translational applications for understanding neurological complications of infections. A significant portion of her recent research addresses SARS-CoV-2-related olfactory dysfunction and the immunological basis of pathogen invasion through the olfactory system into the central nervous system. Dr. Moseman has secured substantial research funding including 'Using tissue-specific Naegleria opportunism to dissect olfactory immunity' (2025-2030), 'Characterizing olfactory plasma cell dynamics and survival niche within the upper airway' (2024-2029), and the 'Advanced Immunobiology Training Program for Surgeons' (2019-2029). She actively contributes to graduate education through the Medical Scientist Training Program (2022-2027) and teaches advanced immunology courses including IMMUNOL 736 and IMMUNOL 494. The Moseman Lab represents a leading center for neuroimmunology research, utilizing in vivo imaging to visualize immune responses within the central nervous system. Their work has significant implications for understanding how pathogens breach neurological barriers and how the immune system protects the brain while preserving essential sensory functions, with potential applications for treating neurological infections and inflammatory conditions.

Virginia W. Cornishمشاهده پروفایل

استاد

• Synthetic Biology
• Protein Engineering
• Chemical Biology
• +۵ مورد دیگر

Virginia W. Cornish is the Helena Rubinstein Professor in the Departments of Chemistry and Systems Biology at Columbia University. She is a pioneer in synthetic biology, focusing on engineering yeast for diagnostic and therapeutic applications. Her research integrates chemical synthesis and genetic tools to expand cellular capabilities, including yeast biosensors and protein engineering. Education: B.A. in Biochemistry, Columbia University (1991) Ph.D. in Chemistry, University of California, Berkeley (1996) Postdoctoral Fellow, MIT (1996–1999) Research Interests: Her work spans synthetic biology, directed evolution, and live-cell imaging. Key areas include: Development of yeast biosensors for pathogen detection Engineering yeast communities for therapeutic applications Expanding the genetic code for noncanonical amino acid incorporation Chemical tagging for protein visualization and manipulation Recent Article Trends: Recent work emphasizes yeast-based biosensors for clinical diagnostics, scalable peptide-GPCR communication systems, and advances in fluorescent tagging for multiplex imaging. Her group also explores genetic code expansion to study protein dynamics and function. Awards: NSF Career Award (2000) Sloan Fellowship (2003) Protein Society Sigal Award (2009) ACS Pfizer Enzyme Chemistry Award (2009) HHMI Gilliam Adviser (2021) Advising & Grants: She advises a dynamic lab of ~20 students/postdocs. Active grants include NIH, NSF, and DARPA funding for synthetic biology and therapeutics. Her team collaborates on projects like vaccine development and metabolic engineering. Labs & Teams: Her lab at Columbia focuses on translational synthetic biology, with facilities for genetic engineering, imaging, and bioassays. Collaborations include projects on yeast-based diagnostics and protein engineering with groups at Harvard, MIT, and Memorial Sloan Kettering.

Rachel Baileyمشاهده پروفایل

پژوهشگر

• Gene Therapy
• Neurodegenerative Diseases
• Tauopathies
• +۷ مورد دیگر

Rachel Bailey is a researcher at UT Southwestern with a focus on developing gene therapies for neurological disorders. She holds dual bachelor's degrees in Biology/Bioinformatics and Molecular Biology from Rensselaer Polytechnic Institute, a Ph.D. in Neuroscience from the University of Florida, and completed postdoctoral research at the University of North Carolina Chapel Hill. Education : Dual B.S. from Rensselaer Polytechnic Institute, Ph.D. in Neuroscience Her research spans gene therapy for monogenic and complex neurodegenerative diseases, including SLC13A5 epileptic encephalopathy , Giant Axonal Neuropathy , and tauopathies like Alzheimer’s disease. She employs AAV vector engineering for gene replacement and silencing, with expertise in preclinical development and IND-enabling studies . Recent publications highlight her work on tau protein phosphorylation in Parkinson’s disease, AAV9 gene therapy for GAN, and autonomic dysfunction in neurodegenerative models. Key collaboration networks include institutions like the NIH and Mayo Clinic.

• Optical Spectroscopy
• Biomedical Imaging
• Chemical Imaging
• +۳ مورد دیگر

Chi (Jesse) Zhang is a Research Professor at Purdue University's Department of Chemistry, leading the Zhang Research Group. His work focuses on developing novel optical spectroscopy, imaging, and opto-control technologies to study chemical processes in living systems. He has pioneered techniques like Real-Time Precision Opto-Control (RPOC) and applies them to biomedical problems, including cancer metabolism and neurodegenerative diseases. His lab collaborates with institutions like Merck and has been recognized with awards such as the Astronaut Scholarship and Alice Watson Kramer Award. Education details are not explicitly provided, but his postdoctoral research at the Beckman Institute (2018–2020) indicates prior training in advanced scientific technology. His research integrates optical engineering with biological systems, emphasizing label-free imaging and real-time manipulation of cellular components. Key achievements include over 50 peer-reviewed publications and the development of the photokinesis technology platform (http://www.photokinesis.tech). His group hosts an active wet lab with projects ranging from lipid metabolism studies to optical device innovation. Recent milestones include successful student defenses, conference presentations, and impactful publications in ACS Photonics , Anal. Chem , and npj Imaging .

Mehdi Kabbageمشاهده پروفایل

استاد

• Necrotrophic fungal pathogenesis
• Programmed cell death in plants
• Plant-microbe interactions
• +۴ مورد دیگر

Mehdi Kabbage is a Professor and Director of Graduate Studies in the Department of Plant Pathology at the University of Wisconsin-Madison . His research focuses on necrotrophic fungal pathogenesis, particularly the role of oxalic acid and programmed cell death (PCD) in plant-pathogen interactions. He teaches courses in fungal biology and plant-microbe interactions. Education : Ph.D. in Plant Pathology (Kansas State University), M.S. in Plant Pathology (Kansas State University), B.S. in Engineering (Ecole d'Ingénieurs de Purpan, France) Dr. Kabbage investigates how Sclerotinia sclerotiorum manipulates plant PCD through oxalic acid secretion and explores strategies to inhibit this process for crop protection. His work spans molecular mechanisms of fungal virulence, plant stress tolerance, and genetic resistance in soybeans. Recent publications highlight his research on fungal effector proteins, host-induced gene silencing, oxalic acid signaling, and autophagy-based resistance strategies. He collaborates extensively on soybean and dry bean pathosystems, with a focus on integrated disease management and climate resilience. His lab develops transgenic approaches for stress tolerance, studies BAG protein family functions in plant defense, and investigates fungal enzymatic virulence factors like alcohol oxidases and laccases. Current projects include chemical genomics for resistance pathway discovery and novel antifungal agents such as poacic acid.

Sabine Emingمشاهده پروفایل

استاد

• Tissue regeneration
• Immunometabolism
• Wound healing
• +۵ مورد دیگر

Professor Sabine Eming is a Principal Investigator at the Department of Dermatology & FMNS at the University of Cologne, affiliated with the CMMC and collaborating with CECAD. Her research focuses on the molecular basis of age-related skin pathologies and regenerative responses. Investigates tissue regeneration, immunometabolism, and TOR signaling Develops therapeutic strategies for injured/aging tissues Uses cross-species models (mice, zebrafish, Drosophila, humans) Her work bridges basic science and clinical expertise to translate findings into therapeutic approaches, particularly examining: Metabolic reprogramming in wound healing Immune system's role in regeneration vs. scarring Lipid synthesis and filaggrin processing in skin barrier formation Scarless repair mechanisms in zebrafish vs. mammals She leads research into molecular control systems including: Cell death regulation (FADD-RIPK3 pathways) Nutrient-sensing TOR pathway in skin aging Glutamine metabolism in stem cell maintenance Her group develops genetically modified mouse models and collaborates on clinical trials for impaired healing conditions.

Alanna (Leni) Greenمشاهده پروفایل

پژوهشگر ارشد

• Bone-Immune-Cancer Interactions
• Cancer Dormancy
• Retinoic Acid Receptor Signaling
• +۳ مورد دیگر

Dr. Alanna (Leni) Green is a Senior Research Fellow at the School of Medicine and Population Health, University of Sheffield. She leads the Cancer and Bone (CAB) Lab, focusing on eradicating chemotherapy-resistant dormant cancer cells in bone. Her academic journey includes a BBiomedSci at Monash University, a PhD at the University of Melbourne, and postdoctoral roles in the Sheffield Myeloma Research Team and Helleday’s lab. Education: BBiomedSci (Hons), Monash University PhD, University of Melbourne Her research explores bone-immune-cancer interactions, particularly how bone microenvironment cells protect tumors from therapy. Key areas include retinoic acid receptor signaling, vitamin A regulation of hematopoiesis, and novel drug development for myeloma and bone-metastatic cancers. Recent publications highlight her work in cancer metabolism (MTHFD2 inhibition), bone repair mechanisms, and microenvironmental regulation of lymphopoiesis. She has received over 20 awards, including Young Investigator Prizes from ECTS and ASBMR. Scientific Awards: Wellcome Trust Career Development Award (2024) Yorkshire Cancer Research Pioneer Advanced Fellowship (2024) Blood Cancer UK Project Grant (2023) Faculty MDH Early Career Researcher Prize (2020) Dr. Green supervises the Cancer and Bone Lab, which includes postdoctoral researchers and PhD students. She lectures on translational oncology and molecular medicine courses and actively contributes to professional societies like the Bone Research Society and ECTS.

• RNA Biology
• Genomics
• Transcriptomics
• +۵ مورد دیگر

Dr. Athma A Pai is an Associate Professor at UMass Chan Medical School, holding primary appointments in the RNA Therapeutics Institute and the T.H. Chan School of Medicine. She maintains extensive secondary appointments across multiple departments including Genomics and Computational Biology, Systems Biology, and several graduate programs at the Morningside Graduate School of Biomedical Sciences, reflecting the highly interdisciplinary nature of her work. Education: BS in Biochemistry/Anthropology from University of Pennsylvania PhD in Human Genetics from University of Chicago Postdoctoral training in RNA Genomics from MIT Dr. Pai's research program centers on RNA biology with particular emphasis on RNA processing, splicing mechanisms, and the regulation of gene expression. Her work investigates how environmental factors influence RNA processing through biochemical, molecular, and genetic mechanisms. She employs cutting-edge genomic and transcriptomic approaches to study alternative polyadenylation, mRNA transcript initiation and termination, and the spatial organization of RNA processing events within cells. Her research has significant implications for understanding fundamental gene regulation mechanisms and their roles in disease processes. Analysis of Dr. Pai's recent publications reveals a strong focus on developing high-resolution profiling methods for understanding transcriptional and translational regulation. Her work increasingly integrates computational approaches with experimental biology to investigate how RNA processing events are coordinated across the transcriptome. A notable trend is her exploration of how RNA processing contributes to inflammatory responses and cellular defense mechanisms, with implications for therapeutic development. Dr. Pai actively mentors students through multiple graduate programs at UMass Chan Medical School, including Biochemistry and Molecular Biotechnology, Biophysical Chemical and Computational Biology, Interdisciplinary Graduate Program, MD/PhD Program, RNA Therapeutics and Biology Program, and Systems Computational and Quantitative Biology. She maintains an active laboratory (Pai Lab) that welcomes postdoctoral researchers interested in RNA biology. Her laboratory website provides additional information about ongoing research projects and opportunities for collaboration and training, and she maintains a professional presence through her Twitter account (@athmapai).

Erez Razمشاهده پروفایل

استاد

• Cell Migration
• Germ Cell Development
• Embryonic Development
• +۴ مورد دیگر

Professor Erez Raz serves as Director of the Institute of Cell Biology at the University of Münster and is affiliated with the Center for Molecular Biology of Inflammation (ZMBE). He is a prominent member of the Cluster of Excellence "Cells in Motion" and serves on the board of the CiM-IMPRS graduate program. His research group "AG Raz: Cell biology in vivo - Germ-cell development" investigates fundamental mechanisms of cell migration in living organisms. Professor Raz's research focuses on cell migration, cell-fate maintenance, and organogenesis within live vertebrate embryos. His laboratory primarily employs zebrafish as a model organism due to its transparent embryos that develop externally, enabling high-resolution live imaging of cellular processes. His work has revealed critical mechanisms of how cells navigate within developing organisms, with significant implications for understanding pathological conditions like cancer metastasis and inflammatory processes where cell migration becomes dysregulated. His recent publications demonstrate a sustained focus on molecular mechanisms controlling germ cell migration, including the roles of RNA-binding proteins like Dnd1, bleb formation dynamics, mitochondrial regulation of germ cell fitness, and tissue microenvironment influences on cell protrusion types. His research uniquely integrates approaches from cell biology, biophysics, genetics, and mathematical modeling to gain comprehensive insights into cellular migration dynamics. Over 100 publications spanning two decades Extensive collaborations across disciplines Methodological innovations in cell imaging and manipulation Professor Raz has successfully mentored numerous doctoral students and postdoctoral researchers, fostering interdisciplinary collaborations between biologists, physicists, mathematicians, and clinicians. His laboratory has developed innovative techniques for cell ablation, mRNA labeling, and in vivo manipulations using optical tweezers, contributing significantly to methodological advances in the field. His laboratory participates in the Multiscale Imaging Centre and the "Cells in Motion" research network, providing access to state-of-the-art imaging capabilities for studying cellular dynamics at multiple scales, from molecular interactions to whole-organism development.

Alvaro Köhn-Luqueمشاهده پروفایل

دانشیار

• Mathematical Oncology
• Computational Biology
• Biostatistics
• +۷ مورد دیگر

Alvaro Köhn-Luque is an Associate Professor at the Oslo Center for Biostatistics and Epidemiology, University of Oslo, and Group Leader at the Department of Medical Genetics, Oslo University Hospital. His work bridges mathematical modeling with clinical applications, particularly in cancer research. His academic background includes a PhD in Mathematical and Computational Biology from Complutense University of Madrid (2012), preceded by multiple Master's degrees in Mathematics and Physics from Spanish universities. Dr. Köhn-Luque's research focuses on mathematical oncology , developing computational models to understand cancer dynamics and improve treatment strategies. His work spans multiscale modeling of tumor growth, personalized cancer medicine through computer simulations, and biomarker discovery using machine learning approaches. He has made significant contributions to modeling breast cancer progression and treatment response, particularly in the context of endocrine therapy and CDK4/6 inhibition. His recent publications demonstrate a strong trend toward integrating mechanistic learning approaches that combine mathematical models with machine learning techniques. This hybrid methodology allows for more accurate prediction of treatment outcomes while maintaining biological interpretability. His work frequently involves collaboration with clinical researchers to ensure models are grounded in real patient data and have direct translational potential. Computational modeling of tumor heterogeneity and drug response Development of methods for phenotypic deconvolution in cancer cell populations Integration of multi-omics data for personalized treatment prediction Application of birth-death processes to model tumor evolution Creation of user-friendly computational tools for biomedical researchers Dr. Köhn-Luque has supervised multiple PhD students including Even M Myklebust, Salim Ghannoum, and Xiaoran Lai, and has secured funding for projects including RESCUE, BigInsight, and Integreat. His research demonstrates a consistent trajectory from theoretical mathematical biology toward increasingly clinically relevant applications in personalized cancer medicine.

Anand Krishnanمشاهده پروفایل

استادیار

• Nerve-tumor interface
• Nerve regeneration
• Cancer biology
• +۵ مورد دیگر

Dr. Anand Krishnan serves as Assistant Professor in the Department of Anatomy, Physiology and Pharmacology at the University of Saskatchewan's College of Medicine, where he leads research on nerve-tumor interfaces and neural macrophage biology. His work bridges neuroscience and oncology to identify therapeutic targets for cancer and neurodegenerative disorders. Education: Postdoctoral Fellow, Division of Neurology, University of Alberta, Canada Postdoctoral Fellow, Clinical Neurosciences, University of Calgary, Canada PhD in Biotechnology (Cancer Biology), Rajiv Gandhi Centre for Biotechnology, India Master of Pharmacy (Pharmacology), Manipal University, India Pharma R&D Experience: Orchid Chemicals and Pharmaceuticals Limited; Alembic Pharmaceuticals Limited Dr. Krishnan's research program investigates two core areas: molecular mapping of tumor-nerve interfaces to uncover novel therapeutic targets, and defining the roles of self-renewing resident macrophages in nervous system homeostasis and disease. His lab employs proteomics, murine models, and in vitro neuronal cultures to explore how tumors and nerves mutually support growth through neural invasion and autonomic signaling. Analysis of his 2020-2024 publications reveals consistent focus on neuro-oncology mechanisms, particularly peripheral nerve regeneration pathways (Myc interactome, growth-primed DRG), tumor-nerve crosstalk (sympathetic signaling in prostate cancer), and neurodegenerative targets (MANF). Key methodologies include comparative proteomics, molecular mapping, and drug repurposing screens. Research Funding: Natural Sciences and Engineering Research Council (NSERC) Cancer Research Society (CRS) CIHR Institute of Cancer Research Breast Cancer Society of Canada (BCSC) Prostate Cancer Fight Foundation (PCFF) & Ride for Dad Saskatchewan Health Research Foundation (SHRF) College of Medicine Research Award (CoMRAD) CoMBRIDGE Fund Start-up Research Fund Based at Saskatoon City Hospital within the Cameco MS Neuroscience Research Centre, the Krishnan Lab trains students supported by NSERC USRA, Dean's project fellowships, OVDR Biomedical research fellowships, and Mitacs awards. The lab's strategic location adjacent to the Meewasin Valley provides collaborative opportunities for translational neuroscience research focused on nerve regeneration and cancer therapeutics.

• Computational Biology
• Molecular Biology
• Cell Biology
• +۵ مورد دیگر

Roy Wollman is a Professor at the University of California, Los Angeles (UCLA) in both the Department of Integrative Biology and Physiology and the Department of Chemistry and Biochemistry within the College of Letters and Science. His work bridges experimental and computational approaches to study dynamic signaling networks and their impact on cellular decisions. Research Focus: Computational and systems biology of signaling pathways Key Techniques: Single-cell analysis, spatial transcriptomics, quantitative modeling Major Themes: Information transmission in biochemical networks, cellular decision-making, epigenetic regulation Recent work has emphasized spatial transcriptomics mapping of brain regions, wound response signaling, and multi-scale analysis from cell biology to physiology. His lab has developed computational tools like scPNMF for gene selection and JSTA for cell segmentation and annotation. Key findings include mechanisms of TNF-induced cell death tradeoffs and laminin scarring effects in stem cell function. Roy Wollman has received continuous NIH funding since 2009, including grants for studying NFκB dynamics (R01GM117134), corneal wound signaling (R01EY024960), and single-cell technologies for traumatic brain injury (R01NS117148). His research combines high-throughput microscopy with computational modeling to understand how cells process dynamic signals.