جست‌وجوی استاد و پژوهشگر

• Breast Cancer
• Clinical Trials
• Oncology
• +۴ مورد دیگر

Associate Professor Nicholas Wilcken is an academic clinician at the University of Sydney's NHMRC Clinical Trials Centre and Central Clinical School. He serves as Director of Medical Oncology at Westmead Hospital and Senior Staff Specialist at Nepean Hospital. His roles include Chair of the SAC for the ANZ Breast Cancer Trials Group and Coordinating Editor of the Cochrane Collaboration Breast Cancer Group. He completed medical studies at UNSW, general medical training at Prince of Wales Hospital, oncology training at Royal Prince Alfred Hospital, and a PhD at the Garvan Institute. His research focuses on breast cancer treatment, clinical trials methodology, and evidence-based guidelines. Wilcken's research interests span breast cancer therapy optimization, systematic reviews, and clinical trial design. His work emphasizes translating evidence into clinical practice, particularly for metastatic and HER2-positive breast cancers. Recent publications include studies on genomic profiling for cancer diagnosis, immunotherapy biomarkers, and treatment decision-making in ER-positive breast cancer. His contributions to oncology include leadership in collaborative breast cancer trials and methodological advancements in systematic reviews. He has authored over 100 peer-reviewed articles across journals like Journal of Clinical Oncology and Cochrane Database of Systematic Reviews . Wilcken actively participates in clinical care and academic leadership, bridging research and practice in oncology.

• Gynecologic Oncology
• Cervical Cancer Prevention
• Ovarian Cancer Treatment
• +۳ مورد دیگر

Dr. Mitchell Clark is an Assistant Professor of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine, affiliated with the Division of Gynecologic Oncology. He holds leadership roles including Assistant Program Director of the Minimally Invasive Gynecological Surgery Program and Associate Director of the Center for Precision Diagnosis of Trophoblastic Disease. Dr. Clark completed residency at Yale New Haven Health and fellowship at Princess Margaret Cancer Center, University of Toronto, where he focused on gynecologic oncology and public health research. Education: MD: AUC School of Medicine (2009) MPH: University of Massachusetts (2023) Fellowship: University of Toronto (2020) Research Interests: Dr. Clark’s research emphasizes cervical cancer prevention via HPV vaccination strategies, improving ovarian cancer surgical outcomes, and addressing health equity in cancer care through population-level data analysis. He investigates disparities in diagnostic timeliness and cancer staging among racial groups, particularly in uterine and cervical cancers. Research Trends: His articles focus on clinical trials of novel therapies (e.g., trastuzumab deruxtecan), minimally invasive surgical techniques (ICG fluorescence-guided lymph node mapping), and leveraging healthcare databases to study systemic disparities in gynecologic cancer care. Awards & Honors: NRG Oncology Early Career Investigator (2021) AAGL Excellence in Minimally Invasive Gynecology (2017) Yale School of Medicine Teaching Award (2017) Grants & Clinical Roles: Leads studies in ovarian cancer treatment and HPV-related cervical disease. Clinically, he directs the Gynecologic Oncology Program at Stamford Hospital and participates in multidisciplinary teams for hyperthermic intraperitoneal chemotherapy (HIPEC) and hepatic arterial infusion (HAI) therapies. Labs & Collaborations: Collaborates with teams including Alessandro Santin, Gloria Huang, and Stefania Bellone on translational research. Active in initiatives like the Connecticut Cancer Partnership and DEI committees within the Society of Gynecologic Oncology.

Anthony J. Bauerمشاهده پروفایل

دانشیار

• Immunology
• Gastroenterology
• Physiology
• +۴ مورد دیگر

Anthony J. Bauer is an Associate Professor of Physiology in the College of Osteopathic Medicine. His research focuses on immunological regulation of gastrointestinal function in disease states such as sepsis, postoperative ileus, and inflammatory bowel disease. He has contributed to understanding mechanisms underlying gastrointestinal dysfunction through studies on cytokines, interstitial cells of Cajal networks, and surgical complications. Bauer has published extensively in peer-reviewed journals and co-authored clinical guidelines for thyroid disorders in children. Education: B.S. in Biology and Psychology, St. Norbert College (1978) Ph.D. in Biomedical Sciences, Eastern Virginia Medical School (1985) National Institutes of Health Postdoctoral Fellowship at Mayo Graduate School Research Interests: Dr. Bauer’s lab investigates immune pathways affecting gastrointestinal motility, particularly in sepsis, trauma, and surgical interventions. Key areas include: Interleukin-10’s role in restoring gastric motility in diabetes Pathophysiology of postoperative ileus and sepsis-induced intestinal failure Translational research on intestinal transplantation and inflammatory bowel disease His work bridges basic science and clinical applications, aiming to improve surgical outcomes and disease management. Recent Article Themes: Recent publications address immunological modulation of gut function, postoperative complications, and genetic factors in cancer predisposition. These studies often employ rodent models and clinical data from multinational databases. Awards & Grants: No specific awards listed, though his sustained research output suggests grant-funded work. Notable collaborations include studies on pediatric thyroidectomy outcomes and DICER1-related tumors. Labs/Teams: Active research projects include five ongoing studies in gastrointestinal immunology, conducted within the Center for Research at his institution.

• Bioinformatics
• Molecular Biology
• Genomics
• +۳ مورد دیگر

Paramjeet Bagga is a Professor of Biology at Ramapo College of New Jersey's School of Theoretical and Applied Science, where he has taught since 1999. He serves as Convener of Bioinformatics and teaches courses including Microbiology, Bioinformatics, and Cell & Molecular Biology. Education: Earned B.S., M.S., M.Phil, and Ph.D. degrees from Guru Nanak Dev University in Amritsar, India. Research Focus: Dr. Bagga's laboratory investigates interactions between cellular proteins and conserved G-quadruplex forming regulatory motifs that influence human gene expression. Using bioinformatics tools developed in his lab, he conducts transcriptome-wide studies of G-quadruplex distribution patterns in genes related to cancer, apoptosis, autism, dementia, and Parkinson's disease. His research frequently involves collaborations with Mathematics and Computer Science faculty and actively engages undergraduate students. Publications: His extensive publication record demonstrates consistent focus on computational biology and gene regulation, particularly concerning G-quadruplex motifs. Recent work emphasizes bioinformatics tool development (QGRS Mapper, GRSDB), database creation for regulatory sequences, and applications in neurological disorder research. Student Engagement: Dr. Bagga mentors undergraduate researchers in bioinformatics projects year-round, with students regularly presenting work at national conferences like ISMB and RNA Society meetings. Academic Development: He established Ramapo College's undergraduate Bioinformatics degree program and maintains an active research laboratory investigating RNA regulatory mechanisms.

Yue Huangمشاهده پروفایل

استادیار

• Computational Genomics
• Somatic Mosaicism
• Neurogenetics
• +۷ مورد دیگر

Yue Huang is an Assistant Professor and Principal Investigator in the Division of Genetics and Genomics at Boston Children's Hospital, affiliated with Harvard Medical School. His research focuses on computational genomics and the role of somatic mutations in human development, aging, and neurodegenerative diseases. BS in Biological Science, Peking University PhD in Bioinformatics, Peking University Postdoctoral Training, Boston Children's Hospital and Harvard Medical School Dr. Huang's research centers on computational genomics , particularly somatic mosaicism in non-cancer contexts. He investigates how postzygotic mutations accumulate in tissues like the brain and heart during aging and contribute to diseases such as Alzheimer’s, autism, and epilepsy. His work integrates single-cell sequencing , bioinformatics tool development , and functional genomics to uncover mutation patterns and their biological impacts. His recent publications reveal trends in neurogenetics and aging , with a focus on identifying somatic variants in neurons and cardiomyocytes. These studies utilize advanced sequencing and computational methods to link mosaic mutations to neurodegeneration and cardiovascular aging, highlighting the role of oxidative stress and DNA repair deficiencies. Dr. Huang's scientific contributions include the development of MosaicHunter and MosaicBase , widely used tools in the field. His research is supported by prestigious grants from the NIH/NIA , NIH/NHLBI , Alzheimer's Association , and Boston Children’s Hospital . He mentors a research team focused on genomic instability and its implications for human health. His lab employs cutting-edge technologies including single-cell multi-omics and deep sequencing to explore cell lineage, mutation burden, and disease mechanisms in the brain and other organs.

• Oncology
• Immunotherapy
• Internal Medicine
• +۷ مورد دیگر

Bashar Abuqayas, MD, is a Clinical Assistant Professor in the Department of Internal Medicine – Hospital Medicine at the University of Iowa, Carver College of Medicine. He is actively engaged in clinical practice and research, focusing on oncology, immunotherapy, and end-of-life cancer care. Research Interests: His work spans several key areas including immune-related adverse events in cancer immunotherapy, outcomes of PD-1/PD-L1 inhibitors, palliative and supportive care in oncology, and the management of renal cell carcinoma. He contributes to both clinical databases and translational research initiatives. The recent publications highlight a consistent focus on cancer immunotherapy , particularly in renal cell carcinoma and treatment-related complications. Themes across his work include patient-centered outcomes, safety of targeted therapies, and quality of end-of-life care in diverse healthcare settings. Scientific Contributions: Co-developer of the REFINE database linking clinical and genomic data in renal cell carcinoma. Contributor to multi-institutional studies on cabozantinib for brain metastases. Researcher in cross-cultural validation of quality-of-life instruments in Jordan. Advising and Grants: While no formal advisees or grant funding are mentioned in the current text, Dr. Abuqayas participates in collaborative research projects involving large datasets and international teams. His involvement in clinical trials and database development suggests engagement with research infrastructure and potential grant-supported work. Labs and Teams: Dr. Abuqayas is affiliated with clinical and research teams at the University of Iowa and previously at King Hussein Cancer Center in Jordan. His work on the REFINE database indicates participation in bioinformatics and precision oncology research groups.

Renee Bouleyمشاهده پروفایل

استادیار

• Antibiotic Resistance
• Biochemistry
• Structural Biology
• +۴ مورد دیگر

Dr. Renee Bouley is an Assistant Professor at The Ohio State University Marion Campus, Department of Chemistry and Biochemistry. She holds a Ph.D. in Organic Chemistry from the University of Notre Dame (2016) and completed postdoctoral research at the University of Michigan (2016–2019). Her research focuses on antibiotic resistance mechanisms, particularly studying L,D-transpeptidases in carbapenem-resistant Enterobacteriaceae (CRE). Techniques employed include X-ray crystallography, protein expression/purification, and structure-based drug design. Collaborations include projects on DNA repair proteins and cancer-related mutations with faculty on both the Marion and Columbus campuses. Education: Ph.D., Organic Chemistry, University of Notre Dame (2016) Postdoctoral Fellow, University of Michigan (2016–2019) B.S., Chemistry, Grand Valley State University (2010) Research Interests: Antibiotic resistance mechanisms Structural biology of L,D-transpeptidases Cancer-related DNA repair pathways RhoGAP proteins in liver cancer Structure-based drug design Key Awards: Eli J. and Helen Shaheen Graduate School Award (2017) Robert M. Scarborough Graduate Award (2017) Dow Chemical Outstanding Graduate Student Award (2016) Lab Focus: Biochemistry lab at Marion Science and Engineering Building (MSE 110H) Undergraduate research opportunities in antibiotic resistance, DNA repair, and cancer biology Collaborations on DNA repair proteins (e.g., RAD52, PRMT5) and RhoGAP mutations

Oliver Bonham-Carterمشاهده پروفایل

دانشیار

• Bioinformatics
• Data Science
• Databases
• +۵ مورد دیگر

Oliver Bonham-Carter is an Associate Professor in the Computer Science Department at Allegheny College. He earned a B.S. in Biology from Creighton University, an M.S. in Mathematics from the University of Nebraska at Omaha, and a Ph.D. in Information Science and Technology with a bioinformatics specialization from the University of Nebraska at Omaha. Education: B.S. (Biology), M.S. (Mathematics), Ph.D. (Information Technology, Bioinformatics) Research: Gene expression analysis, text mining of scientific literature, bioinformatics-driven encryption His research explores bioinformatics through three main facets: (1) statistical pattern detection in biological big data, (2) signal localization in protein regions, and (3) text mining of PubMed literature. He developed tools like GenExSt for gene interaction analysis and BeagleTM for literature connectivity mapping. Recent articles focus on ethical pedagogy in CS education (2024), text mining for disease-related gene correlations (2023-2021), and mitochondrial protein stress responses (2016). These works span computational biology, data analysis, and responsible technology design.

Chen Yiranمشاهده پروفایل

استاد

• Mass Spectrometry
• Proteomics
• Peptidomics
• +۷ مورد دیگر

Chen Yiran is a Researcher at the Agricultural Biotechnology Research Center, Academia Sinica , where he has contributed to mass spectrometry , proteomics , and plant immunity . He serves as Chairman of the Taiwan Mass Spectrometry Society and holds Professor positions at National Chung Hsing University (Center for Biotechnology Development), National Taiwan University (Institute of Biotechnology/Systems Biology Program), and National Taiwan Ocean University (Department of Life Science and Biotechnology). His work spans peptidomics , DNA adductomics , and plant-microbe interactions . Chen's research integrates mass spectrometry with bioinformatics to study environmental health risks, plant immune signaling, and disease mechanisms. His team has developed tools like the FeatureHunter software for adduct detection and UniQua signal processor for proteomics. Current projects include CAPE9 peptide characterization for plant immunity and oxidative stress analysis in metabolic disorders. 2025: Outstanding Talent Development Foundation Leap Lecture 2024: Taiwan Mass Spectrometry Society Outstanding Scholar Award 2016: Academia Sinica Young Scholars Research Book Award 2015: Yang Xiangfa Agricultural Sciences Young Scholar Award Laboratory members include doctoral students Ying Guangting , Anciotti , and Jiefan . The lab operates at Academia Sinica's Agricultural Science Building A523 , with equipment for advanced chromatography-mass spectrometry and proteome analysis . Collaborations span National Taiwan University , Stanford , and UC Davis alumni networks.

• Pain Neurobiology
• Transcriptomics
• Bioinformatics
• +۵ مورد دیگر

Allison Barry (BSc, MSc, DPhil) is a Canadian-British-German pain neurobiologist currently conducting postdoctoral research at the University of Vienna and University of Texas at Dallas . Formerly a DPhil student at University of Oxford under Prof. David Bennett and Prof. Georgios Baskozos, she specializes in multi-omics approaches to pain pathophysiology, focusing on dorsal root ganglia (DRG) proteomics , spatial compartmental profiling , and iPSC-derived nociceptor modeling . Her work is rooted in open science advocacy and chronic migraine patient perspectives. Education: BSc Neuroscience (2015), Dalhousie University MSc Neurosciences (2017), Max Planck Institute/University of Göttingen DPhil Ion Channels & Disease (2022), University of Oxford Research Focus spans neuropathic pain mechanisms , multi-omics data integration , and sex-specific pain pathways . She employs spatial proteomics , proximity labeling , and synaptosome profiling to dissect sensory neuron subtypes in disease contexts. Her lab-generated DRG Directory database hosts processed sequencing datasets for community reuse. Publication Trends reveal interdisciplinary work bridging neuroscience with bioinformatics , emphasizing TNFα signaling , NKG2D ligand discovery , and neuroimmune interactions . Her methodological critiques (e.g., limitations of silhouette scores in single-cell analysis) highlight rigor in computational pain research . Grants & Collaborations: Funded by NIH, Wellcome Trust, and former Medical Research Council/NSERC support, she collaborates with teams across Harvard , King’s College London , and MDC Berlin . Her work intersects with open science movements and chronic migraine advocacy . Labs & Networks: Previously affiliated with Oxford’s Neural Injury Group, she now contributes to Vienna’s Starkl Lab (immunology focus) and Dallas’ WeirLab (chronic pain reversal strategies). She actively engages with global consortia like Bioconductor and PAIN Journal editorial initiatives.

Karen Curtinمشاهده پروفایل

دانشیار

• Genetic Epidemiology
• Cancer Epidemiology
• Colorectal Cancer
• +۷ مورد دیگر

Karen Curtin, PhD, MStat is an Associate Professor in the Department of Internal Medicine, Division of Epidemiology at the University of Utah School of Medicine and an adjunct Associate Professor in Ophthalmology and Visual Sciences at the John A. Moran Eye Center. She serves as Interim Director of the Utah Population Database (UPDB) at Huntsman Cancer Institute and is affiliated with the Pedigree and Population Resource. Dr. Curtin is a Huntsman Cancer Institute investigator in the Cancer Control and Population Sciences program and a Co-Investigator with the Steele Center for Translational Medicine at the Moran Eye Center. Dr. Curtin received her PhD in biomedical informatics with an emphasis in genetic epidemiology from the University of Utah, where she was awarded the John D. Morgan Fellowship Award in Biomedical Informatics. She completed post-doctoral training in molecular and risk factor epidemiology at Utah and holds an MStat degree. Before her academic career, she worked as a Master's level biostatistician on large population-based cancer studies. Her research focuses on genetic epidemiology and population-based science, with specific interests in gene-environment interactions, cancer epidemiology (particularly colorectal cancer), environmental pollution, epigenetics in cancer, and age-related macular degeneration with co-segregating diseases. She has developed expertise in using the Utah Population Database for population-based research on gastrointestinal cancers, breast density in relation to interval breast cancer, and genetic underpinnings of myeloid disorders. Her work often involves cross-disciplinary collaborations across University of Utah Health Sciences Center, Huntsman Cancer Institute, and Intermountain Healthcare. Dr. Curtin's recent publications show a strong focus on exfoliation syndrome and its systemic associations, colorectal cancer epidemiology, and genetic susceptibility to various cancers. Her research demonstrates consistent integration of population-based approaches with translational applications, particularly in ophthalmology and cancer prevention. Among her notable honors are the John D. Morgan Fellowship Award in Biomedical Informatics, an invitation to speak at the prestigious Lindberg Society Symposium at the 2018 World Ophthalmology Congress, and an award from the BrightFocus(R) Foundation's National Glaucoma Research Program to study prognostic factors in exfoliation glaucoma. As Interim Director of the Utah Population Database, Dr. Curtin oversees a resource supporting over 290 active research projects. She collaborates extensively with investigators across multiple disciplines, particularly in cancer epidemiology, ophthalmology, and population health. Her research infrastructure expertise has led to productive collaborations with translational and clinical investigators in age-related macular degeneration, exfoliation syndrome/glaucoma, and gastrointestinal cancers. Dr. Curtin maintains active laboratory research through the Curtin Group, which utilizes the Utah Population Database linked to University of Utah and Intermountain Healthcare records, including complex radiology and pharmacy data, to study cancer epigenetics and epidemiology across multiple disease domains.

Trine Ballestad Roungeمشاهده پروفایل

استاد

• Bioinformatics
• Genomics
• Epigenomics
• +۵ مورد دیگر

Trine Ballestad Rounge is a Professor at the Section for Pharmacology and Pharmaceutical Biosciences at the University of Oslo. Her research focuses on genomics, epigenomics, transcriptomics, and microbiome-related research with the primary goal of identifying biomarkers in tissues, biofluids, or associated microbes that reveal early-stage cancer progression. Her research interests include: Bioinformatics and molecular biology Development of sequencing protocols and advanced bioinformatics analyses Identification of cancer biomarkers through genomic, epigenomic, and microbiome approaches Development of bioinformatics tools including GENOMICON-Seq, VirMake, HoCoRT, and TAME-seq Dr. Rounge leads several major research projects including CRCbiome (funded by the Norwegian Cancer Society and HSØ), which aims to identify biomarkers in the gut microbiome for colorectal cancer screening. She is the Norwegian PI for the Genome of Europe project, part of the 1+MG initiative, collaborating with Helsedirektoratet and Elixir. She also leads the JanusRNA project funded by the Norwegian Research Council, which aims to identify circulating RNAs as cancer biomarkers using serum samples. In this project, her team has analyzed more than 4000 samples from pre-diagnostic samples across seven different cancer sites. Her scientific work shows a strong focus on cancer biomarker discovery, particularly using multi-omics approaches. Her recent publications demonstrate expertise in microbiome analysis, circulating RNA profiling, and bioinformatics tool development. Her research spans colorectal cancer, ovarian cancer, endometrial cancer, testicular germ cell tumors, and HPV-related cancers. Dr. Rounge collaborates extensively with researchers across Europe and leads cross-institutional groups working on genomic events in persistent HPV infection. Her work bridges computational biology with clinical applications, aiming to translate genomic findings into practical cancer screening tools.

Jörg Gsponerمشاهده پروفایل

استاد

• Computational Biochemistry
• Protein Interactions
• Intrinsically Disordered Proteins
• +۵ مورد دیگر

Dr. Jörg Gsponer is Professor and Head of the Department of Biochemistry & Molecular Biology at the University of British Columbia's Faculty of Medicine, with a joint appointment at the Michael Smith Laboratories in the Faculty of Science. Appointed as Department Head in November 2024 after serving as interim Head since February 2024, he has been at UBC since 2009 and was promoted to Professor in 2021. Dr. Gsponer holds a dual degree in medicine and theoretical biophysics through the Swiss MD-PhD program. His educational background includes an MD from the University of Lausanne (1997), a PhD in Biochemistry from the University of Zurich (2002), post-doctoral training at the University of Cambridge Chemistry Department (2003), and MRC Research Fellow at the Laboratory of Molecular Biology in Cambridge (2006). His research focuses on intrinsically disordered proteins (IDPs) and their connections to cancer and neurodegeneration. Using advanced computational methods, molecular modeling, simulations, and bioinformatics approaches, his lab explores how protein structure and interactions contribute to cellular phenotypes. Recent work has incorporated generative AI tools like AlphaFold to advance protein biochemistry research. The lab has developed several computational tools including MoRFchibi, GraPES, and LIST for predicting protein features and interactions. Dr. Gsponer's research has resulted in numerous high-impact publications, particularly in areas of protein-protein interactions, intrinsically disordered regions, and computational approaches to understanding disease mechanisms. His work shows strong trends toward integrating AI with traditional biochemical approaches to solve complex problems in protein science. Michael Smith Foundation for Health Research Career Investigator Distinguished Achievement Award for Overall Excellence from UBC Faculty of Medicine As Department Head, Dr. Gsponer emphasizes team leadership and delegation, working with an executive team to advance scientific knowledge and innovate in training the next generation of scientists. He has spearheaded initiatives in data science teaching and recruitment in generative AI and nanomedicine. His lab continues to secure research funding for projects exploring protein interactions in disease contexts, with particular focus on cancer and neurodegenerative disorders. The Gsponer Lab maintains strong collaborations across multiple disciplines and institutions, operating within the Centre for High-Throughput Biology (CHiBi) at the Michael Smith Laboratories. The lab environment fosters interdisciplinary research combining computational approaches with experimental validation to address fundamental questions in protein science.

• Hematology-Oncology
• Acute Myeloid Leukemia
• Acute Lymphoblastic Leukemia
• +۵ مورد دیگر

Dr. Ayman Qasrawi is an Assistant Professor of Internal Medicine at the University of Kentucky. A board-certified hematologist-oncologist, he completed medical school at Hashemite University (2012), residency at the University of Missouri-Kansas City (2018), and a post-doctoral fellowship at the University of Kentucky (2021). His work directly supports UN Sustainable Development Goals in health and well-being, with a focus on equitable cancer care. Dr. Qasrawi’s research portfolio centers on acute leukemias , myelodysplastic syndromes , stem-cell transplantation , and the genomic epidemiology of obesity-associated malignancies . He employs molecular diagnostics, real-world data, and AI-driven analytics to refine risk stratification and personalize therapy. His investigations explore: Molecular mechanisms underlying therapy resistance in AML and ALL. Impact of obesity on mutational landscapes and clinical outcomes. Optimization of allogeneic and autologous transplant regimens. Novel FLT3, CD123, and BCL-2 targeted therapies. Across 2024–2025, his peer-reviewed output demonstrates a clear trend toward translational studies integrating genomics , clinical trial data , and population-based outcomes to advance leukemia therapeutics. Notable themes include comparative effectiveness of targeted agents (gilteritinib vs midostaurin), timing of transplant interventions, and safety evaluation of CAR-T and hypomethylating agents. Scientific Awards & Honors: While specific named awards are not detailed in the provided text, Dr. Qasrawi’s role as Principal Investigator on multiple phase-2/3 industry-sponsored trials and his substantial citation record (h-index 7, 113 citations) underscore recognition within the hematology-oncology community. Research Funding & Leadership: He currently leads or co-leads 11 active or recently funded projects totaling multi-million-dollar support from Daiichi-Sankyo, Novartis, Kura Oncology, Sanofi, and OncoVerity. These studies span randomized placebo-controlled trials of quizartinib, venetoclax combinations, CAR-T strategies in SLE, and novel FLT3 inhibitors. Laboratory & Clinical Teams: Dr. Qasrawi directs clinical research efforts embedded within the University of Kentucky’s Markey Cancer Center, collaborating with interdisciplinary teams in pathology, bioinformatics, and translational therapeutics to accelerate discovery-to-bedside pipelines.

Andrew Kossenkovمشاهده پروفایل

استادیار

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۷ مورد دیگر

Andrew Kossenkov, Ph.D. serves as an Assistant Professor at The Wistar Institute, specifically within the Vaccine & Immunotherapy Center and the Genome Regulation and Cell Signaling Program of the Ellen and Ronald Caplan Cancer Center. His career trajectory began with bachelor's and master's degrees in computer science and bioinformatics from Moscow Engineering Physics Institute in Russia, followed by a Ph.D. in biomedical science from Drexel University in Philadelphia. He joined The Wistar Institute in 2007 as a postdoctoral fellow in the Showe lab and subsequently became managing director of the Bioinformatics Facility before his 2019 appointment as Assistant Professor. Dr. Kossenkov's research focuses on applying computational approaches to analyze various kinds of biomedical high-throughput data, with particular expertise in interpreting results and visualizing complex datasets. His laboratory collaborates extensively with other Wistar labs on research projects spanning cancer, infectious diseases, and fundamental biological questions including regeneration, stem cell biology, mitochondrial proteins, transcriptional regulation, synapse biology, blood development, and global epigenetic gene silencing. The Kossenkov Laboratory relies heavily on bioinformatics analysis of drug screen results, next-generation sequencing data, and proteomics. His publication record reveals a strong focus on cancer immunology, particularly ovarian cancer, melanoma, and breast cancer, with significant contributions to understanding how metabolic reprogramming, mitochondrial dynamics, and immune microenvironment interactions influence tumor progression and treatment response. His work often bridges computational biology with experimental validation through extensive collaborations across multiple institutions including Fox Chase Cancer Center, The Children's Hospital of Philadelphia, the University of Pennsylvania, Drexel University, New York University, Weill Cornell, and Harvard. Through his leadership of the Bioinformatics Facility, Dr. Kossenkov provides critical expertise for high-throughput data support, analysis, and annotation, developing database-oriented gene annotation pipelines and algorithms to visualize highly specific and intricate results. His laboratory offers flexible and customizable support for a wide range of experiments across multiple research domains, making significant contributions to both computational methodology development and biological discovery.