جستجوی استاد راهنمای دانشگاهی

• Cancer Modeling
• DNA Methylation
• Epigenetics
• +۳ مورد دیگر

Kimberly Siegmund, PhD, is a Professor of Population and Public Health Sciences at the University of Southern California. She serves as Associate Chief of Education in Biostatistics, integrating advanced statistical methodologies with biomedical research. Her work focuses on cancer modeling, DNA methylation, and epigenetic data analysis in human diseases, particularly in prostate cancer, bladder cancer, and pediatric leukemia. Dr. Siegmund’s research combines mathematical and computational approaches to understand tumor growth, metastasis, and the impact of environmental factors on epigenetic profiles. Her research interests include the development of statistical models for high-dimensional data, epigenetic biomarker discovery, and the role of DNA methylation in disease progression. She has contributed significantly to understanding the epigenetic mechanisms underlying cancer heterogeneity and has pioneered methods for analyzing mutational signatures in tumors. Dr. Siegmund’s publications span over three decades, addressing topics such as epigenome-wide association studies, the impact of smoking and air pollution on methylation patterns, and the application of statistical frameworks to cancer epidemiology. Her work often bridges clinical and population-level analyses, with a focus on translational research to improve diagnostic and prognostic tools. Key collaborations include the Southwest Oncology Group (SWOG) and the Colorectal Cancer Family Registry, emphasizing her commitment to interdisciplinary cancer research. She has also developed computational tools like Methcon5 and iMutSig to advance epigenetic and mutational signature analyses.

• Environmental Engineering
• Nanotechnology
• Materials Science
• +۳ مورد دیگر

Xiangyu Chen is a Lecturer at the Department of Civil, Environmental and Geomatic Engineering, ETH Zürich. He is affiliated with the Luftqualität u. Partikeltechnolog (Air Quality and Particle Technology) research group. His contact information includes the email xiangchen@ethz.ch and is located at HIF D 27.1, Laura-Hezner-Weg 7, 8093 Zürich, Switzerland. His research focuses on nanotechnology and materials science applied to environmental engineering, biomedical diagnostics, and energy systems. Key areas include: Development of advanced sensors for air quality and biomedical applications Catalytic material design for energy efficiency Biomedical nanomaterials for targeted drug delivery and imaging Xiangyu Chen’s recent publications (2021–2024) highlight innovations in nanoparticle-based technologies, including 3D metal-organic frameworks for energy systems, deformable organosilica nanoparticles for MRI contrast agents, and real-time in vivo imaging techniques for glioma targeting. His work bridges theoretical material science with practical sensor and medical applications. No scientific awards or grants are explicitly mentioned. He mentors students within his teaching role but no specific advisees are listed. His affiliation with the Air Quality and Particle Technology group aligns with environmental nanotechnology research.

Marianne Bronnerمشاهده پروفایل

استاد

• Cellular and Developmental Biology
• Evolutionary Biology
• Neuroscience
• +۵ مورد دیگر

Marianne Bronner is the Edward B. Lewis Professor of Biology and Director of the Beckman Institute at the California Institute of Technology. She holds a Sc.B. from Brown University (1975) and a Ph.D. from Johns Hopkins University (1979). Her career at Caltech spans roles including Ruddock Professor (2000-21), Distinguished Professor (2021), and Executive Officer (2013-16). Her research focuses on neural crest development, integrating molecular, cellular, and evolutionary approaches. Key areas include neural crest induction, placode formation, and their roles in craniofacial and sensory organ development. She explores evolutionary innovations like the vertebrate head by comparing lamprey, amphioxus, and jawed vertebrates. Her lab investigates mechanisms of cell migration, epigenetic regulation, and oncogenic processes linked to neural crest-derived cancers. Techniques employed include transcriptomics, CRISPR/Cas9, laser speckle imaging, and lineage tracing in chick, zebrafish, and lamprey models. Recent work highlights neural crest contributions to heart regeneration and neurofibromatosis modeling in zebrafish. The lab collaborates with the Caltech Women in STEM initiative and has pioneered tools for in vivo imaging and genetic manipulation. Lab Leadership: Bronner Lab at Caltech Key Projects: Neural crest gene regulatory networks, placode evolution, cancer biology Tools: Laser speckle imaging, CRISPR, lineage tracing Her work bridges developmental, evolutionary, and translational research, with implications for birth defects, cancer, and regenerative medicine.

Margherita Bertuzziمشاهده پروفایل

مدرس

• Molecular Microbiology
• Fungal Pathogenesis
• Host-Pathogen Interactions
• +۳ مورد دیگر

Dr. Margherita Bertuzzi is a Lecturer in Molecular Microbiology at the University of Manchester, affiliated with the Division of Evolution, Infection and Genomics and the Manchester Fungal Infection Group (MFIG). She holds roles as Co-Director of the MSc Infection Biology program and PGT Unit Lead for Host-Pathogen Interaction lectures and Research Project II. Her research focuses on fungal infection biology, particularly the antifungal phagocytic activities of respiratory epithelia in health and disease, with emphasis on pH-mediated signaling and COPD-related dysfunctions. She leads a team employing single-cell technologies and immunological analyses to study fungal-epithelial interactions. Education: BSc (Hons) Molecular Biology, University of Padua, Italy (2002-2005) MRes Human Health Biology, University of Padua, Italy (2005-2007) PhD Molecular Mycology, Imperial College London, UK (2007-2011) Research Interests: Her work explores epithelial encounters with respiratory pathogens, immune response modulation, and translational applications. Key areas include Aspergillus fumigatus pathogenesis, COPD exacerbations, and host-microbe interactions using cutting-edge imaging and single-cell techniques. Awards: MRC Discovery award (2017) MRC New Investigator Research grant (2021) Teaching & Mentoring: She delivers lectures on molecular mycology, mentors PGT students, and oversees research projects. Recent supervisees include PhD candidates (e.g., Patrick Dancer) and MSc/MRes students (e.g., Anna Möslinger, Caitlin Sergienko). Labs & Collaborations: Collaborations with Manchester University NHS Foundation Trust and the National Aspergillosis Centre support clinical translation. Her lab integrates interdisciplinary approaches to address fungal infection challenges aligned with UN SDG 3 (Good Health).

• Histone biology
• Chromatin structure
• Epigenetics
• +۴ مورد دیگر

Dr. Siavash K. Kurdistani is a Professor in Biological Chemistry and Pathology & Laboratory Medicine at the David Geffen School of Medicine, UCLA . With a dual MD (1999) and PhD background, his research spans chromatin biology, histone functions, and their implications in cancer and neurodegenerative diseases. Department Chair, Biological Chemistry Co-Director, UCLA Broad Stem Cell Research Center Member, UCLA Molecular Biology Institute His research focuses on: Histone post-translational modifications Metal ion homeostasis via chromatin Epigenetic-metabolic crosstalk Chromatin structure and disease mechanisms Evolution of chromatin regulatory systems Transcriptional regulation in cancer Key recent publications reveal histones as metabolic regulators with enzymatic activities (copper/zinc reductase) impacting yeast aging (2025), neurodegeneration (2021), and cancer metabolism (2022). His work on MLLT3 (2019) and nuclear deformation (2022) has been widely cited. Honors include: ASCI membership (2019) Kavli Fellow (2011) NIH Director's Innovator Award (2009) HHMI Early Career Award (2006-2009) Beckman Young Investigator (2007) He has secured multiple NIH grants and collaborates across biochemistry, medicine, and systems biology. The Kurdistani Lab (est. 2004) employs yeast, cancer cells, and stem cells to investigate chromatin's role in disease. Current projects explore histone biochemistry in Friedreich's ataxia and epigenetic reprogramming in neuroendocrine cancers.

David Knudsenمشاهده پروفایل

استاد

• Veterinary Pathology
• Infectious Diseases
• Zoonotic Viruses
• +۳ مورد دیگر

David Knudsen is a Professor and Veterinary Pathologist at the Animal Disease Research and Diagnostic Laboratory (ADRD) of South Dakota State University (SDSU), where he also serves as an instructor for courses VET 601 and VET 648 in the Professional Program in Veterinary Medicine. His academic background includes a B.S. (1979) and D.V.M. (1982) from Colorado State University, an M.S. (1985) from the University of Missouri, and residencies in Veterinary Pathology and Laboratory Animal Medicine. He is a Diplomate of the American College of Laboratory Animal Medicine. Knudsen's research focuses on veterinary pathology, infectious diseases, zoonotic viruses, and cancer stem cell biology. His work spans bovine, swine, avian, and wildlife systems, with notable contributions to understanding astrovirus in cattle, influenza in horses and swine, and avian influenza in Egyptian poultry and raptors. He has also explored the therapeutic potential of natural compounds like phenethyl isothiocyanate in targeting cancer stem cells. His publications (2008–2023) highlight interdisciplinary approaches, including vaccine development against enterotoxigenic E. coli, viral pathogenesis studies, and environmental impacts on wildlife health. His lab at ADRDL collaborates on diagnostic and translational research to address emerging diseases in livestock and wildlife, emphasizing One Health principles. Knudsen’s professional service includes teaching, diagnostic pathology, and contributions to laboratory animal medicine standards. His office is located in Room 1122, Animal Disease Research and Diagnostic Laboratory, SDSU.

Huy Dinhمشاهده پروفایل

استادیار

• Cancer Immunology
• Single-Cell and Spatial Omics
• Neutrophil Heterogeneity
• +۵ مورد دیگر

Huy Dinh is an **Assistant Professor** at the University of Wisconsin-Madison, with a joint appointment in the **Department of Biostatistics and Medical Informatics** and the **McArdle Laboratory for Cancer Research** (School of Medicine and Public Health). His research focuses on **computational analysis of single-cell and spatial omics data** to understand cancer immunology, neutrophil heterogeneity, and tumor microenvironment dynamics. He leads the Dinh Lab, which employs interdisciplinary approaches combining experimental and computational methods. **Education & Career**: Ph.D. in Bioinformatics (University of Vienna), postdoctoral training at USC/Cedars Sinai Medical Center and La Jolla Institute for Immunology. Joined UW-Madison as a **Human Precision Medicine Cluster Hire** in 2020. **Research Interests**: Anti-tumoral neutrophil phenotypes and their roles in immunotherapy response Neutrophil activation in burn injury and wound healing High-dimensional data integration (single-cell RNA-Seq, spatial transcriptomics) **Key Achievements**: NIH MIRA R35 Award (2023) Over 30 peer-reviewed publications, including work in Nature Genetics , Immunity , and Clinical Cancer Research Lab has pioneered methods to identify neutrophil subpopulations in cancer and inflammation **Lab Members**: Mentors ~20 trainees across PhD, MD, and undergraduate programs. Notable advisees include Athena Golfinos-Owens (PhD, 2025) and Parth Khatri (PhD candidate). **Grants & Collaborations**: Leads projects on neutrophil heterogeneity in burns (NIH-funded) and collaborates with institutions like Stanford and the NIH.

Ivan Marazziمشاهده پروفایل

دانشیار

• Epigenetics
• Transcriptional Regulation
• NF-kappaB Signaling
• +۲ مورد دیگر

Ivan Marazzi is Associate Professor of Biological Chemistry at UC Irvine School of Medicine, leading the Center for Epigenetics & Metabolism. Research explores transcriptional regulation dynamics, NF-kappaB signaling, and chromatin organization in inflammation and host-virus interactions. Recent investigations focus on circadian control of immunity, DNA damage responses, and therapeutic targeting of inflammatory pathways. The lab employs molecular biology and genomics approaches to study transcriptional mechanisms in viral infections, cancer, and immune disorders.

• homologous recombination
• DNA repair
• genome instability
• +۵ مورد دیگر

Yi Yin is an Assistant Professor in the Department of Human Genetics at the University of California, Los Angeles (UCLA) School of Medicine. Her research focuses on understanding homologous recombination (HR), a major pathway for repairing double-strand breaks in DNA, which has critical implications in cancer biology, development, and genome stability. Dr. Yin received her PhD and MS in Genetics and Genomics and Statistical Science, respectively, from Duke University in 2015. Her educational background has equipped her with a strong foundation in both biological mechanisms and quantitative analysis. Her research interests center on building a probabilistic understanding of homologous recombination through the development of high-throughput single-cell sequencing technologies. The central vision of her lab is to develop tools that can predict genome fragility, identify epigenetic contexts regulating DNA breakage, determine how DNA repair gene variants affect repair processes, and understand the consequences of HR from single cells to individuals. She has developed the sci-L3 suite of single-cell sequencing technologies, which enables linear amplification of single-cell genomes at scale (up to 1 million cells) and supports multi-omics applications including whole-genome sequencing, targeted sequencing, and DNA/RNA co-assays. Analysis of Dr. Yin's publication record reveals a consistent research trajectory focused on DNA repair mechanisms, particularly using yeast as a model organism to study homologous recombination. More recently, her work has expanded to include SARS-CoV-2 genomic epidemiology, demonstrating the versatility of her genomic technologies. Her publications show increasing impact, with several highly cited papers in top journals like Nature Biomedical Engineering, Molecular Cell, and Nature Biotechnology. Damon Runyon-Dale F. Frey Award for Breakthrough Scientists, Damon Runyon Cancer Research Foundation (2020-2022) Damon Runyon Fellowship Award, Damon Runyon Cancer Research Foundation (2016-2019) Dr. Yin serves as Principal Investigator on NIH R35GM142511 "Understanding spontaneous mitotic crossover by single-cell multi-omics" (2021-2026), which supports her development of a full-fledged HR mapping platform. Her lab is working to characterize genome, tissue, and evolutionary variation in mitotic HR rates and machinery, with broader interests in genome-wide characterization of HR partner choice, cell-type variation in DNA repair pathway usage, construction of dense linkage maps in non-model organisms, and discovery of new DNA repair genes in unculturable microbes. The Yin Lab @ UCLA continues to push the boundaries of genomic technology development and its application to fundamental biological questions.

• Tectonics
• Geophysics
• Seismic Analysis
• +۳ مورد دیگر

Dr. Rebecca Bell is a Lecturer in Geology and Geophysics at Imperial College London, part of the Faculty of Engineering. She holds a PhD in Marine Geophysics from the University of Southampton and a Master's in Earth Science from the University of Oxford. Her research focuses on tectonic evolution, utilizing seismic and drilling data to study subduction zone fault mechanics and rift development. Key affiliations include the Basins Research Group, the Grantham Institute, and the Imperial Centre for Geohazards. Her work addresses critical questions such as controls on subduction zone fault behavior and the dynamics of continental rifting. Recent projects include deploying seismometers in New Zealand to study slow slip events and leveraging machine learning for earthquake hazard assessment. She has held prestigious roles like the Imperial College Research Fellowship (2012–2017) and editorial positions in journals like Basin Research . Teaching accolades include winning the Best Feedback Award in 2013 and being shortlisted in 2016. Her research has been widely featured in media outlets like Nature World News and Aljazeera America . Her publications span seismic imaging, CO2 migration, and fault mechanics, reflecting her interdisciplinary approach. Ongoing initiatives include fully funded PhD and postdoctoral positions investigating subduction zone seismic behavior, emphasizing fault zone properties and their societal implications.

Samira Sadat Hosseini Alghaderiمشاهده پروفایل

پژوهشگر ارشد

• Developmental Biology
• Molecular Biology
• Cell Biology
• +۳ مورد دیگر

Samira Sadat Hosseini Alghaderi is a Research Fellow and Research Associate in the Division of Evolution, Infection and Genomics at The University of Manchester. She holds a PhD in Medicine (2021) from The University of Manchester, an MRes in Tissue Engineering and Regenerative Medicine (The University of Manchester), and a BSc in Biomedical Science from Mashhad University of Medical Sciences. Her research focuses on Notch signaling pathways, endocytosis mechanisms, and their roles in development and disease. Key areas include the regulation of Notch receptors via ubiquitin ligases and endosomal trafficking, with applications to cancer and regenerative medicine. Collaborations span molecular biology and genetics, leveraging both Drosophila models and human systems. Notable achievements include organizing the Postgraduate Summer Research Showcase (2017–2019) and serving as Postdoctoral Research Associates (PDRA) Representative (2021–2024). Awards include the T4E Award (2024), Manchester Doctoral College Award (2020), and President’s Doctoral Scholar Award (2016).

Richard D. Pressمشاهده پروفایل

استاد بالینی

• Molecular Diagnostics
• Oncology
• Hematology
• +۳ مورد دیگر

Richard D. Press is a Clinical Professor and Medical Director of Molecular Pathology and the Molecular Diagnostics Center at the OHSU Knight Cancer Institute. He also serves as Program Director for the Molecular Genetic Pathology Fellowship. His research focuses on molecular diagnostic biomarkers in cancer and infectious diseases, as well as genetic alterations in common diseases. Dr. Press holds an M.D. and Ph.D. from Case Western Reserve University (1988), with residency training in Pathology and a fellowship in Molecular Pathology at the University of Pennsylvania. He is board-certified in Clinical Pathology and Molecular Genetic Pathology. Education: B.A., 1981, Northwestern University M.D./Ph.D., 1988, Case Western Reserve University Residency: Pathology, University of Pennsylvania Fellowship: Molecular Pathology, University of Pennsylvania Research Interests: Molecular diagnostics in oncology and infectious diseases Genetic biomarkers in acute myeloid leukemia (AML) and other hematologic malignancies Clonal evolution and measurable residual disease (MRD) in leukemia Publications Overview: His work spans molecular characterization of leukemia subtypes, validation of diagnostic assays, and clinical applications of next-generation sequencing (NGS). Recent studies investigate NUP98-rearranged AML, T-lineage childhood leukemia, and resistance mechanisms in chronic myeloid leukemia. Labs/Teams: Director of the Molecular Diagnostics Center at OHSU, leading cutting-edge diagnostic research and training programs for pathologists.

Jennifer Hooperمشاهده پروفایل

دانشیار

• Maternal-Newborn Nursing
• Nursing Education Strategies
• Computer-Based Testing in Nursing
• +۳ مورد دیگر

Jennifer Hooper is an Associate Professor at Mount Royal University's School of Nursing & Midwifery in Calgary, Canada. She holds dual licensure in Canada and the U.S., maintaining active clinical practice in maternal-newborn nursing. Her roles include curriculum development, leadership, and teaching in the Bachelor of Nursing and Bridge to Canadian Nursing programs. Education: MN from University of Calgary; BScN from Saint Francis Xavier University. Research focuses on innovative teaching strategies for nursing students, particularly computer-based testing preparation, and maternal-newborn health issues like postpartum depression and NICU experiences. Active with the Mokakiiks Centre for Scholarship of Teaching and Learning. Publications emphasize health assessment techniques and nursing education innovations. Community involvement includes hospice care and postpartum service improvements. Grants and lab affiliations not explicitly detailed but implied through research activities.

• Nanoporous metals
• Electrochemical biosensors
• Multifunctional neural interfaces
• +۶ مورد دیگر

Erkin Şeker, Ph.D. , is a Professor in the Department of Electrical and Computer Engineering at the University of California, Davis, where he also serves as Co-Director of the Center for Neuroengineering and Medicine and Chair of the Designated Emphasis in Neuroengineering . His research integrates micro- and nanofabrication, electrochemical biosensors, multifunctional neural interfaces, and microfluidic tissue chips to address challenges in healthcare and life-science miniaturization. Education: Ph.D. in Electrical Engineering, University of Virginia (2007) Research Interests Prof. Şeker’s group operates at the intersection of nanoporous metals , microfluidics , and device engineering . Current thrusts include: Nanostructured electrochemical biosensors for nucleic-acid detection in food safety, water quality, and medical diagnostics. Multifunctional biomedical device coatings that combine neural recording with on-demand drug delivery to combat epilepsy and other neurological disorders. Nanoporous metal morphology libraries for high-throughput investigation of structure–property relationships. Microphysiological models of neuroinflammation and gut–brain-axis interactions using tri-culture tissue chips. Publication Trends Over the past decade the group has produced >80 peer-reviewed articles spanning Analytical Chemistry , ACS Applied Materials & Interfaces , Advanced Functional Materials , Lab on a Chip , and Journal of Neuroinflammation . The work reveals a clear trajectory from fundamental studies of nanoporous gold mechanics and surface chemistry to translational applications in closed-loop neural control, nucleic-acid diagnostics, and tissue-level disease models. Scientific Awards & Honors NSF CAREER Award NIH NIBIB Trailblazer Award UC Davis Academic Senate Distinguished Graduate and Professional Teaching Award UC Davis Graduate Studies Distinguished Graduate and Postdoctoral Mentorship Award BMES Cellular & Molecular Bioengineering Young Innovator Next Level Research Award (College of Engineering) Fund for Medical Discovery Award (Massachusetts General Hospital) Elevation to IEEE Senior Member Advising & Funding Prof. Şeker has mentored >25 Ph.D. and M.S. students and numerous undergraduates. Active funding includes NSF, NIH (NIBIB, NINDS, NIA, NCCIH), USDA-NIFA, UC Lab Fees, and industry partnerships totaling several million dollars. He is PI or Co-PI on grants such as: "NeuralStorm: Taking Neuroengineering by Storm" (NSF NRT) "Closed-Loop Electro-Fermentation…" (USDA-NIFA) "Next-Generation Neural Interfaces Based on Axonal Confinement…" (NIH NIBIB Trailblazer) "A Scalable Primary Cortical Tri-Culture Model…" (NIH R03) Labs & Teams He directs the Şeker Research Group , a multidisciplinary team of graduate students, post-docs, and undergraduates housed in the UC Davis College of Engineering. Shared resources include College clean-room facilities, the Center for Neuroengineering and Medicine, and collaborative ties with the UC Davis Alzheimer’s Disease Research Center, Comprehensive Cancer Center, and Environmental Health Sciences Center.

Frank Schubertمشاهده پروفایل

استاد

• Developmental Biology
• Evolutionary Biology
• Genetics
• +۶ مورد دیگر

Dr. Frank Schubert is an academic at the University of Portsmouth, serving as Associate Head (Research and Innovation) and PhD Supervisor in the School of Biological Sciences under the Faculty of Science and Health. He holds affiliations with the Institute of Life Sciences and Healthcare , Institute of the Earth and Environment , and Centre of Excellence for Heritage Innovation . Education: Dr. Schubert studied Biology at the Universities of Kiel and Heidelberg, graduating in 1989. He earned his PhD at the Max-Planck Institute of Biophysical Chemistry (1989–1994) under Prof. Peter Gruss, focusing on Hox cluster evolution. Research Interests: His primary research explores gene regulatory networks controlling neurogenesis and cell fate in early brain development, axon guidance of pioneer tracts, and brain vascularization. He also investigates evolutionary mechanisms through phylogenetic reconstruction and ancient DNA analysis of museum samples. His chicken embryo model aids in studying pediatric brain tumors. Publication Trends: His work spans developmental neurobiology, evolutionary genetics, and biomedical applications, with recent studies on axon scaffold conservation (2025), avian models (2024), and skeletal muscle dynamics (2023). Keywords like Developmental Biology Neurobiology Evolutionary Genetics Biomedical Research dominate his contributions. Teaching: He lectures on modules such as Biodiversity and Evolution, Genetics, Cell Biology, and Bioinformatics, emphasizing developmental and evolutionary themes. Collaborations: Dr. Schubert partners with Dr. Susanne Dietrich, Dr. Garry Scarlett, and Dr. Sam Robson on projects involving axon guidance, ancient DNA, and biomedical models.