جستجوی استاد راهنمای دانشگاهی

Michael Turner is a Professor of Materials Chemistry and Director of the Organic Materials Innovation Centre (OMIC) at the University of Manchester's School of Chemistry. He holds a Chair in Materials Chemistry and leads the Knowledge Centre for Materials Chemistry (KCMC), a virtual interdisciplinary research hub. His research focuses on synthesizing conjugated molecules for applications in organic electronics, including transistors, LEDs, sensors, and solar cells. He coordinates the EPSRC-funded Organic Materials for Electronics Consortium (OME-C), involving collaborations across multiple institutions. Education: Bachelor's and PhD from the University of Bristol (organometallic chemistry with Prof. Selby Knox). Postdoctoral work in the U.S. with Prof. Harry Allcock on polyphosphazenes, followed by research at the University of Sheffield on Fischer-Tropsch reactions under Prof. Peter Maitlis. Research Interests: Synthesis of conjugated liquid crystals and polymers, organic electronics, electro-optical devices, and nanoscale fabrication. His work addresses challenges in energy, environment, and material synthesis through novel polymer architectures and functional nanoparticles. Key Projects: Principal Investigator for KCMC, advancing applied materials chemistry and knowledge transfer. Leading projects on CRISPR-Cas technology integration into organic electronics and roadside breath analysis of narcotics. Contributions to neuromorphic computing via printed electronics and bioelectronics networks. Awards: Royal Society University Research Fellowship (1993). Grants & Collaborations: Coordinates EPSRC consortia and collaborates internationally on polymer synthesis, sensor systems, and bio-inspired materials. His work aligns with UN Sustainable Development Goals, particularly energy and environmental innovation. Labs & Teams: Directs OMIC and KCMC, fostering interdisciplinary research in organic materials, device fabrication, and nanotechnology applications.

• Materials Chemistry
• Organic Electronics
• Conjugated Polymers
• +۵ مورد دیگر

Harrison Steel is an Associate Professor of Engineering Science at the University of Oxford and Tutorial Fellow at Harris Manchester College. He holds a BEng in Mechanical Engineering and BSc in Physics and Mathematics from the University of Sydney, followed by a DPhil at Oxford as a Monash Scholar. His research focuses on synthetic biology, control engineering, and bioprocess optimization, with a particular emphasis on microbial systems and genetic circuit design. Dr. Steel’s work integrates computational modeling, experimental biology, and control theory to engineer robust biological systems. His contributions include advancements in genome editing via SIBR-Cas systems, cybernetic control of microbial co-cultures, and the development of open-source platforms like Chi. Bio for automated biological experimentation. His recent publications highlight innovations in directed evolution strategies, modular biomolecular control architectures, and the application of machine learning to fitness landscape analysis. He has pioneered approaches for stabilizing genetically engineered cell populations and enhancing bioprocess efficiency through adaptive control systems. Dr. Steel’s research is supported by collaborations across engineering, biology, and computational disciplines. He actively contributes to academic leadership through his role at Harris Manchester College and maintains an experimental focus on bridging theoretical models with practical biological implementations.

• Synthetic Biology
• Biomedical Engineering
• Systems Biology
• +۴ مورد دیگر

Dr. Tracey Gloster is a researcher in the School of Biology at the University of St Andrews, focusing on the structure and function of carbohydrate processing enzymes and CRISPR-Cas systems. Her work contributes to understanding biological roles of carbohydrates in cellular processes and their malfunction in diseases like cancer and neurodegenerative disorders. She leads projects such as 'Expanding the structural biology toolkit' funded by The Royal Society and has been a PI on Wellcome Trust grants. Research Interests: Carbohydrate processing enzymes (e.g., heparan sulfate degradation) CRISPR-Cas systems and anti-CRISPR proteins Cyclic nucleotide signaling and protein activation mechanisms Structural biology and enzymology Recent Publications Trends: Her articles emphasize CRISPR defense mechanisms, cyclic nucleotide regulation of nucleases, and bioinformatic tools for CAZyme analysis. Key topics include anti-CRISPR proteins, enzyme inhibition strategies, and structural insights into CRISPR effectors. Awards: 2012 Biochemical Society Early Career Research Award 2016 Election to Young Academy of Scotland 2013 L'Oreal-UNESCO For Women In Science Fellowship Grants & Activities: She has secured funding for structural biology projects and collaborates on advanced mass spectrometry tools. Active in organizing workshops (e.g., Scottish Structural Biology) and hosting academic visitors. Served as an external PhD examiner at the University of York. Labs/Teams: Engaged in interdisciplinary research within the Institute of Engineering Biomedical Sciences Research Complex, focusing on structural biology and enzymology applications.

• Structural Biology
• Enzymology
• CRISPR Mechanisms
• +۳ مورد دیگر

Thomas Mock is Professor of Marine Microbiology at University of East Anglia's School of Environmental Sciences and Adjunct Professor at Ocean University of China. Research investigates phytoplankton adaptation and evolution in polar/oceanic environments through integrative approaches spanning cell biology, genomics, and ecology. Education includes: PhD (University of Bremen) MSc Biological Oceanography (Christian-Albrechts University) Research examines fundamental biological processes governing marine microalgae adaptation, with focus on diatom evolution under climate change. Current projects include: KRILLGUARD: Safeguarding Southern Ocean ecosystems Light-driven proton pumps in oceanic primary production Arctic microbial biodiversity in warming oceans Leads the Mock Research Lab with 14+ members and directs the UEA-OUC Strategic Alliance in Ocean Science. Received CAS President's International Fellowship (2024) and serves as Co-Editor-in-Chief for Journal of Phycology.

• Marine Microbiology
• Phytoplankton Adaptation
• Polar Biology
• +۲ مورد دیگر

Lu Shin Wong is a Senior Lecturer in Chemical Biology and Biological Chemistry at the University of Manchester's School of Chemistry, affiliated with the Manchester Institute of Biotechnology. He holds a PhD from the University of Southampton and has expertise in biocatalysis and nanofabrication. His research focuses on sustainable chemical processes, enzyme-driven reactions, and nanoscale material fabrication. Wong has held postdoctoral roles at Manchester and Northwestern University, and leads projects in biocatalytic applications, nanotechnology, and bioelectronics. Education: PhD in Organic and Analytical Chemistry (University of Southampton, 2005); BPharm (University of Nottingham, 1997); Postgraduate Diploma in Clinical Pharmacy (University of Bradford, 2001). Research Interests: Biocatalysis (enzyme-mediated organosilicon chemistry, sustainable oxidations); Nanofabrication (scanning probe lithography, polymer pen lithography). His work bridges biotechnology and nanotechnology, emphasizing sustainable synthesis and biomedical applications. Recent projects include the Manchester Bioelectronics Network and CRISPR-Cas technology integration into organic electronics. Key Achievements: Developed methods for protein immobilization using phosphopantetheinyl transferase, pioneered biocatalytic approaches to silicone polymer synthesis, and contributed to understanding stem cell behavior on nanostructured substrates. Active in interdisciplinary collaborations, including bioelectronics and mass spectrometry advancements.

• Biocatalysis
• Nanofabrication
• Chemical Biology
• +۳ مورد دیگر

Shirley Graham is a Research Fellow at the University of St Andrews School of Biology, focusing on CRISPR-Cas bacterial immune systems. Her work examines molecular mechanisms of type III CRISPR effectors, antiviral signaling pathways, and nuclease regulation. Key research areas include: Cyclic nucleotide signaling in antiviral defense Structural enzymology of CRISPR-associated nucleases CRISPR system regulation and inactivation mechanisms Bacterial-phage coevolution Recent publications characterize novel CRISPR ancillary effectors, antiviral signaling via ATP-SAM conjugation, and structural foundations of type III CRISPR complexes. Work increasingly explores therapeutic applications for antibacterial strategies and phage resistance engineering. Methodological strengths include structural biology (cryo-EM), bioinformatic discovery of defense systems, and biochemical analysis of enzyme kinetics. Research contributes to the National Center for Smart Growth and integrates computational predictions with experimental validation of immune mechanisms.

• CRISPR-Cas Systems
• Antiviral Immunity
• Nuclease Enzymology
• +۲ مورد دیگر

Professor Mark Enright is a Professor of Medical Microbiology at Manchester Metropolitan University's Department of Life Sciences, specializing in genomic epidemiology of antibiotic-resistant pathogens and bacteriophage therapy development. His work bridges clinical microbiology with advanced genomic techniques to combat multidrug-resistant infections. His educational background includes: PhD in Medical Microbiology, University of Aberdeen (1995) MSc in Biochemistry, University of Dundee (1990) BSc (Hons) in Biological Sciences, University of Stirling (1989) Enright's research focuses on antibiotic resistance mechanisms in Gram-positive and Gram-negative pathogens, with groundbreaking work on bacteriophage-based therapeutics targeting Staphylococcus aureus , Pseudomonas aeruginosa , and Klebsiella pneumoniae . His laboratory employs whole-genome sequencing and core-genome MLST to track pathogen evolution, biofilm formation, and horizontal gene transfer. Recent projects include developing phage cocktails against cystic fibrosis-related infections and characterizing depolymerases for capsular polysaccharide degradation. Analysis of his 2015-2025 publications reveals consistent focus on genomic epidemiology of healthcare-associated pathogens, with increasing emphasis on phage therapy applications. His work demonstrates methodological evolution from traditional typing to advanced genomic analyses, particularly in tracking international MRSA transmission and developing phage-based biofilm disruption strategies for wound infections. His major recognitions include: Royal Society University Research Fellowship (2000-2008) European Society for Clinical Microbiology Young Investigator Award (2002) As Editor of the International Journal of Antimicrobial Agents and Section Editor for FEMS Microbiology Letters , Enright shapes antimicrobial research discourse. He serves on editorial boards of Antibiotics and PeerJ , and reviews for Science and Nature . His grant review expertise for Wellcome Trust, MRC, and EU programs informs global research funding priorities. Formerly a Visiting Professor at University of Bath (2011-2014), he maintains strong industry-academia collaborations in antimicrobial development. His Molecular Microbiology teaching integrates cutting-edge research into curriculum, while his John Dalton Building laboratory develops novel approaches to combat antimicrobial resistance through phage genomics and biofilm disruption technologies.

• Medical Microbiology
• Antibiotic Resistance
• Bacteriophage Therapy
• +۲ مورد دیگر

Stineke Van Houte is a Professor at the University of Exeter, Department of Biosciences, and a BBSRC Future Leader Fellow. She leads research on host-parasite interactions, focusing on CRISPR-Cas systems and antimicrobial resistance. Her work integrates microbiology, evolutionary biology, and ecology to understand bacterial defense mechanisms against phages and plasmids. She holds a PhD from Wageningen University (2014) and has held postdoctoral roles at the University of Exeter and University of Bologna. Research Interests: Her lab explores how CRISPR-Cas systems can be harnessed to combat antimicrobial resistance, particularly targeting resistance genes in microbial communities. She investigates phage-bacteria co-evolution, bacterial immune responses, and the dynamics of plasmid-mediated resistance. Key areas include CRISPR-Cas immunity, phage defense evasion strategies, and ecological drivers of resistance spread. Scientific Awards: Recipient of the BBSRC Future Leader Fellowship (2018–2020) and Marie Sklodowska Curie Research Fellowship (2016–2017). Her work is funded by BBSRC grants focusing on CRISPR-based antimicrobial strategies. Labs & Collaborations: Director of the Van Houte Lab (https://vanhoutelab.wordpress.com), collaborating across disciplines to advance microbial ecology and genetic engineering.

• Host-parasite interactions
• CRISPR-Cas systems
• Antimicrobial resistance
• +۳ مورد دیگر

Pedro Estrela is a Professor in the Department of Electronic & Electrical Engineering at the University of Bath, where he directs the Centre for Bioengineering & Biomedical Technologies (CBio). His research focuses on developing label-free electrical biosensors and chemical sensors for applications in medical diagnostics and environmental monitoring. Key areas include electrochemical impedance spectroscopy, nanobiosensors, microfluidics, and organ-on-chip technologies. Prof. Estrela holds a Doctor of Philosophy in Physics from the University of Amsterdam and a Master of Physics in Condensed Matter Physics from the University of Lisbon. His multidisciplinary work involves collaborations with engineers, chemists, biologists, and clinicians. Recent publications demonstrate strong emphasis on nanotechnology-enabled diagnostic platforms, including SARS-CoV-2 detection systems, sepsis biomarkers quantification, and transdermal microneedle devices. Research trends indicate increasing integration of nanomaterials, CRISPR technology, and additive manufacturing for developing point-of-care diagnostics. The work consistently addresses global health challenges through innovations in rapid testing and environmental surveillance. Prof. Estrela leads multiple collaborative projects in water monitoring and nanomedicine, supported by substantial research grants. His laboratory focuses on translating fundamental discoveries into practical biomedical solutions through industry partnerships.

• Biosensors
• Chemical Sensors
• Nanobiosensors
• +۵ مورد دیگر

Professor Tim Blower is an Honorary Professor in the Department of Biosciences at Durham University and a member of the Biophysical Sciences Institute Executive Board. His research focuses on toxin-antitoxin systems and bacteriophage interactions, exploring molecular mechanisms of bacterial defense against phages and their implications for antimicrobial resistance. He employs structural biology, biochemistry, and genetic approaches to study these systems. Key research interests include: Antimicrobial resistance mechanisms Phage-host interactions and defense systems Structural analysis of bacterial toxins and enzymes Molecular basis of phage immunity Toxin-antitoxin system regulation His work has led to significant contributions, including studies on the BREX defense system, nucleotidyltransferase toxins, and Mycobacterium tuberculosis pathogenesis. He has been awarded the Lister Institute Prize Fellowship (2019) and the Springboard Award (2017). Prof. Blower supervises a team of PhD students, including Aditi Biswas, Beth Hardman, and Tom Arrowsmith, among others. His research group investigates topics such as phage defense modularity, tRNA modification by toxins, and structural engineering of bacterial defense proteins.

• Antimicrobial Resistance
• Bacteriophage biology
• Biochemistry
• +۴ مورد دیگر

Tiffany Taylor is Professor and Royal Society Dorothy Hodgkin Senior Research Fellow at University of Bath, investigating evolutionary drivers of gene regulatory networks through microbial experimental evolution. Education includes PhD in Evolutionary Biology from University of Oxford (2011) and BSc (Hons) from University of Edinburgh (2008). Fellow of Higher Education Academy. Research combines molecular biology and bioinformatics to study how environmental change shapes regulatory networks in bacteria and cancer evolution. Current projects examine bacterial genome defense systems and transcription factor rewiring. Funded by BBSRC and Royal Society, including fellowship renewal for genetic/environmental drivers of novel regulation (2023-2026). Awards include Royal Society Senior Research Fellowship. Service includes Rosalind Franklin Award Committee (2018-2021). Science communicator with children's books on evolutionary biology.

• Experimental Evolution
• Gene Regulatory Networks
• Microbial Evolution
• +۳ مورد دیگر

Professor Alexander Yakunin is a faculty member at Bangor University's School of Environmental and Natural Sciences, specializing in enzyme discovery, enzymology, and biocatalysis applications. He holds a PhD in Microbiology from the Winogradsky Institute of Microbiology (1987) and an MSc in Molecular Biology from Moscow State University (1978). His research focuses on extremophilic enzymes, bioremediation of plastics/microplastics, and CRISPR-associated enzymes. Key projects include enzyme applications in biocatalysis and scaling-up engineering biology for environmental solutions. Research interests include enzyme stability under extreme conditions, lignin degradation, and microbial detoxification of fluorinated compounds. His work aligns with UN SDG goals for sustainable development and environmental protection. Recent projects include a £42k grant for microbial bioaugmentation in anaerobic digestion and collaborations on synthetic biology pathways for biofuel production. Publications highlight enzyme engineering, CRISPR-Cas systems, and applications in plastic recycling. His lab explores novel enzymes from metagenomic libraries and archaeal extremophiles, contributing to industrial biotechnology and environmental sustainability.

• Enzyme Discovery
• Enzymology
• Biocatalysis
• +۴ مورد دیگر

Professor Garry Blakely serves as Chair of Microbial Genetics and Biotechnology at the University of Edinburgh, where he has maintained an active research program since 1999. His work bridges fundamental bacterial genetics with translational applications in biomedicine and industrial biotechnology, focusing on pathogenic bacteria including Bacteroides , Clostridium , Staphylococcus , and Streptococcus . His academic foundation includes: Ph.D. from Queens University of Belfast (1990) MRC postdoctoral research at University of Glasgow (1990-1994) MRC postdoctoral research at University of Oxford (1994-1998) Wellcome Trust RCD Fellowship (1998-2002) Blakely's research centers on four interconnected themes: bacterial chromosome dynamics, restriction-modification systems, polysaccharide biosynthesis, and host-microbiome crosstalk. His laboratory pioneered genetic tools for manipulating anaerobic pathogens like B. fragilis and C. difficile , revealing mechanisms of DNA damage response critical to antibiotic efficacy. The landmark discovery of BfUbb—a bacterial ubiquitin homologue with antimicrobial properties—established a novel molecular link between gut microbiota and autoimmune disorders such as lupus and rheumatoid arthritis through antigenic mimicry. Analysis of his 2013-2019 publications reveals consistent thematic evolution: early work focused on restriction-modification systems and chromosome biology, while later research expanded into microbiome-autoimmunity connections and biotechnological applications like antimicrobial coatings. His studies integrate genomic, biochemical, and clinical approaches across fundamental microbiology, immunology, and materials science. Scientific recognition includes: Wellcome Trust RCD Fellowship Blakely actively supervises PhD students and secures collaborative funding from medical research councils and industry partners. His projects translate basic discoveries into novel biotechnological solutions, including engineered bacterial strains for compound production and medical device coatings that prevent bacterial adhesion. Current grants support investigations into BfUbb's role in autoimmune pathogenesis and development of next-generation antimicrobials targeting anaerobic pathogens. He leads a multidisciplinary research group within the University of Edinburgh's Roger Land Building, maintaining active collaborations with Queen's University Belfast and industrial partners to advance bacterial genetics research toward clinical and industrial applications.

• Bacterial Genetics
• Genomics
• Biochemistry
• +۴ مورد دیگر

Laura Spagnolo is Professor of Biophysical Chemistry in the Molecular Biosciences department at the University of Glasgow and Group Leader at the Research Complex at Harwell. She co-founded the Scottish Centre for Macromolecular Imaging and leads research on genome editing mechanisms using integrated structural biology approaches. She holds an MSc in Pharmacy from the University of Trieste and a PhD from the University of Padova/EMBL Heidelberg. Her research focuses on: Structural mechanisms of CRISPR systems and DNA repair complexes Macromolecular assemblies in genome editing and RNA metabolism Multi-scale structural analysis from atomic to cellular resolution Her publications demonstrate consistent focus on structural biology of DNA/RNA-processing complexes, with recent work emphasizing CRISPR machinery, DNA repair systems, and archaeal biology using cryo-EM and biochemical approaches. Active grants include: BBSRC funding for Staufen protein microscopy (2024-2027) MRC support for electron microscopy modernization (2022-2023) BBSRC project on DNA recombinases (2022-2025) Scottish Funding Council grants for macromolecular imaging (2018-2021) She directs the Spagnolo research group studying genome engineering complexes and collaborates with the Scottish Macromolecular Imaging Centre.

• Structural Biology
• Genome Editing
• DNA Repair
• +۳ مورد دیگر

Dr. Ahmed Salman is a Senior Immunologist-Vaccinologist and Research Group Leader at the Jenner Institute, University of Oxford, affiliated with Kellogg College. He specializes in developing vaccines against infectious and cancerous diseases, focusing on malaria, COVID-19, and veterinary pathogens. His work employs advanced technologies like viral vectors, viral-like particles (VLPs), and CRISPR-based approaches. He holds a DPhil in Clinical Medicine from the University of Oxford, following degrees from Ain Shams University and collaborations with institutions like the Statens Serum Institut. Research Interests: Dr. Salman’s research centers on identifying vaccine antigens, optimizing vaccine platforms, and advancing gene therapy for retinal diseases. His contributions include patents for malaria vaccines and pivotal roles in the Oxford-AstraZeneca COVID-19 vaccine development. He leads projects funded by the Bill & Melinda Gates Foundation and MRC, focusing on antigen selection for clinical trials. Grants & Awards: His work has been supported by major funders, and he holds patents for malaria vaccine candidates. He is a member of the British Society for Immunology and American Society of Tropical Medicine and Hygiene. Publications: His recent work spans malaria vaccine mechanisms, retinal immunology, and cybersecurity applications of AI. Contributions include studies on CRISPR delivery to the retina and AI frameworks for cybersecurity education.

• Immunology
• Vaccinology
• Molecular Biology
• +۴ مورد دیگر