جست‌وجوی استاد و پژوهشگر

David John Procterمشاهده پروفایل

استاد

• Organic Synthesis
• Catalysis
• New Synthetic Methods
• +۵ مورد دیگر

David John Procter is a Professor of Organic Chemistry and Head of the Department of Chemistry at the University of Manchester. His career includes academic roles at the University of Glasgow (Lecturer, Senior Lecturer) and a Readership at the University of Manchester, where he became a Professor in 2008. His research focuses on developing new synthetic methods, catalysis, and materials chemistry, with applications in drug discovery, biocatalysis, and organic electronics. Education: BSc Chemistry (University of Leeds, 1992), PhD (1995, supervised by Prof. Christopher Rayner). Postdoctoral work: Florida State University (Prof. Robert Holton, Taxol analog synthesis). Research interests include samarium diiodide-mediated reactions, metal-free coupling processes, and sustainable synthesis methods. He leads projects funded by EPSRC, Industry (30 grants), and international collaborations. Awards include the EPSRC Established Career Fellowship (2015–2020), Bader Prize (2014), and Young Heterocyclic Chemist Award (2015). Key contributions: Total synthesis of natural products (e.g., pleuromutilin), development of copper-catalyzed multicomponent couplings, and innovative methods for organic materials. His work aligns with UN Sustainable Development Goals related to affordable and clean energy and responsible consumption. Collaborations span academic and industrial partnerships in chemistry, physics, and biology. He supervises 60+ students and contributes to the Organic Materials Innovation Centre (OMIC). His group’s research is detailed at proctergroupresearch.com .

Mario P. Wiesenfeldtمشاهده پروفایل

پژوهشگر

• Organic Chemistry
• Photoredox Catalysis
• Radical Chemistry
• +۲ مورد دیگر

Dr. Mario P. Wiesenfeldt is an independent research group leader at Ruhr-Universität Bochum and the Max-Planck-Institut für Kohlenforschung, affiliated with the Cluster of Excellence RESOLV. His laboratory focuses on developing synthetic organic methodologies using photoredox catalysis and radical intermediates to address challenges in medicinal chemistry. Education: PhD in Organic Chemistry (WWU Münster, 2015–2019) M.Sc. Chemistry (Ruprecht-Karls-Universität Heidelberg, California Institute of Technology) B.Sc. Chemistry (Ruprecht-Karls-Universität Heidelberg) Research Interests: Dr. Wiesenfeldt's work integrates physical organic chemistry with synthetic methodology, emphasizing solvent effects, radical stability, and photoredox activation. Key areas include: Development of bioisosteres for drug discovery Stereoselective hydrogenation of (hetero)arenes Mechanistic studies of radical intermediates Sustainable catalysis under mild conditions Publication Trends: His recent work demonstrates a strong focus on photoredox-mediated transformations (2023–2024), expanding into medicinal chemistry applications like cubane bioisosteres. Earlier publications (2017–2020) established expertise in enantioselective hydrogenation and fluoroarene chemistry. Awards and Honors: Thieme Chemistry Journals Award (2022) Liebig Scholarship, Fonds der Chemischen Industrie (2021) GDCH Prize for university innovation (2021) Leopoldina Postdoctoral Scholarship (2019) WWU Dissertation Prize (2018) Evonik Prize (2018) Research Group: Leads the Wiesenfeldt Lab at ZEMOS (Centre for Molecular Spectroscopy), supervising four PhD students. The lab utilizes state-of-the-art facilities for organic synthesis and collaborates with RESOLV for solvation science studies.

Thomas Lectkaمشاهده پروفایل

استاد

• Organic Chemistry
• Synthetic Chemistry
• Physical Organic Chemistry
• +۳ مورد دیگر

Thomas Lectka is the Jean and Norman Scowe Professor in the Department of Chemistry at Johns Hopkins University, where he has been a faculty member since 1994. His research focuses on synthetic and physical organic chemistry, particularly in the area of organofluorine chemistry. PhD, Cornell University Postdoctoral Fellow, Heidelberg (Alexander von Humboldt Fellow) Postdoctoral Fellow, Harvard University (NIH Fellow) Dr. Lectka's research is centered on developing novel synthetic methods, especially for fluorination, and understanding the physical organic principles underlying reactivity. His work spans radical fluorination , catalytic asymmetric synthesis , and the design of fluorinated bioactive molecules . Using a combination of experimental and computational techniques, his lab investigates C-F bond formation , reaction mechanisms , and the biological applications of fluorinated compounds. His recent work, as reflected in publications from 2010 to 2024, shows a consistent trajectory in advancing fluorination methodologies, with increasing emphasis on site-selectivity , enantiocontrol , and biomedical relevance . Themes include the development of new reagents, mechanistic studies, and the synthesis of fluorinated natural product analogs and peptidomimetics. Dr. Lectka has received numerous honors and awards, including: ACS Arthur C. Cope Scholar (2024) ACS Maryland Chemist of the Year (2017) John Simon Guggenheim Memorial Fellowship Dreyfus Teacher-Scholar Award Sloan Fellowship NSF CAREER Award NIH First Award Eli Lilly Grantee Award He actively mentors graduate and undergraduate students in his research group, contributing to education and training in organic chemistry. His lab, The Lectka Group , is supported by grants from the NIH and NSF, enabling cutting-edge research in synthetic methodology and physical organic studies. The group fosters a collaborative environment focused on innovation in fluorine chemistry. The Lectka Group is an active research laboratory at Johns Hopkins University dedicated to pushing the boundaries of synthetic organic chemistry through the exploration of fluorine's unique properties. Current projects include site-selective radical fluorination and the synthesis of unusual fluorinated species, aiming to provide new tools for drug discovery and materials science.

Giacomo Crisenzaمشاهده پروفایل

مدرس

• Catalysis
• Electrochemistry
• Photocatalytic Synthesis
• +۳ مورد دیگر

Dr. Giacomo Crisenza is a Lecturer in Catalysis at the Department of Chemistry, University of Manchester. His research focuses on developing sustainable electrochemical and photocatalytic methods for converting carbon feedstocks into value-added chemicals. He holds a PhD from the University of Bristol and has held academic positions at Manchester since 2020. Education: PhD in Chemical Synthesis, University of Bristol (2013–2017) MSc and BSc, Università degli Studi di Milano (2007–2012) Chemical Synthesis CDT, University of Bristol (2012–2013) Research Interests: Electrochemical synthesis of novel organic compounds Photocatalytic activation of aromatic systems Design of sustainable catalytic protocols Radical-mediated C–C bond formations Development of carbon feedstock valorization strategies Articles Trends: His recent work emphasizes photocatalytic C–H functionalization strategies, asymmetric total syntheses, and metal-free arylation approaches. Key themes include visible-light-driven reactions and transition-metal catalyzed transformations. Advising & Grants: Supervised 2 PhD students (specific names not listed). Actively seeks external funding through schemes like MSCA and NIF for postdoctoral researchers. Labs & Teams: Leads the Crisenza Group within the Organic Chemistry Group at Manchester, focusing on net-zero catalysis and sustainable chemical synthesis.

• Cancer Research
• Pharmacology
• Medical Imaging
• +۴ مورد دیگر

Mark Steven Cohen is the Dean and Senior Vice President & Chief Academic Officer at Carle Illinois College of Medicine. He holds the title of Professor in multiple departments including Biomedical and Translational Sciences, Clinical Sciences, Bioengineering, and affiliated institutes like Beckman Institute for Advanced Science and Technology. His research focuses on cancer pharmacology, drug repurposing (e.g., sulfasalazine for adrenocortical carcinomas), Hsp90 inhibitors for melanoma treatment, and medical imaging technologies integrated with mixed reality for clinical training. Recent work emphasizes overcoming drug resistance in melanoma via C-terminal Hsp90 inhibitors and advancing healthcare innovation through mixed reality applications. Cohen has contributed to over 121 scholarly publications and media engagements, including commentaries on AI’s impact on healthcare and the LCME accreditation of Carle Illinois College of Medicine. His interdisciplinary collaborations span bioengineering, genomic biology, and clinical sciences, reflecting his role as a founder professor in bioengineering and his leadership in translational research initiatives.

• Medicinal Chemistry
• Natural Products Synthesis
• Anti-parasitic Drug Development
• +۳ مورد دیگر

Tim O'Sullivan is a Senior Lecturer in Pharmaceutical Chemistry at University College Cork (UCC), holding joint appointments in the School of Pharmacy and School of Chemistry. He specializes in medicinal chemistry, natural products synthesis, and drug development targeting parasitic, bacterial, and viral diseases. His research focuses on Chagas disease, cystic fibrosis-related biofilm inhibition, and anti-HIV therapies. Dr. O'Sullivan holds a BSc in Industrial Chemistry from the University of Limerick and a PhD in natural products synthesis from the Australian National University. His academic career includes postdoctoral roles at Trinity College Dublin and University College Dublin, followed by a research manager position at UCD before joining UCC in 2006. He has secured significant grants from bodies like the Irish Research Council and Horizon 2020, totaling over €1M. Notable recognitions include the SEFS Student-nominated Staff Award (2022) and the Tetrahedron Award (2008). Research interests span synthesizing bioactive compounds, developing novel antiparasitics (e.g., Plakortide P analogs), and disrupting bacterial quorum sensing to combat antibiotic resistance. Collaborations involve institutions like the Universitat Autònoma de Barcelona and the Leibniz Institute in Germany. He mentors multiple PhD students and teaches courses in pharmaceutical chemistry and organic synthesis.

Apurba Duttaمشاهده پروفایل

دانشیار

• Medicinal Chemistry
• Synthetic Organic Chemistry
• Anti-Infectives
• +۳ مورد دیگر

Apurba Dutta is an Associate Professor and Interim Chair in the Department of Medicinal Chemistry at the University of Kansas School of Pharmacy. His research focuses on asymmetric synthesis of bioactive molecules, development of synthetic methodologies, and natural product-based drug discovery. He holds a Ph.D. in Chemistry from North-Eastern Hill University (1989) and completed postdoctoral research at the University of Kansas (1994) and a Humboldt Fellowship at the University of Konstanz (1992). Research Overview : Dr. Dutta’s work includes total synthesis of antifungal peptidyl nucleosides (e.g., polyoxins, nikkomycins), proteasome inhibitors like salinosporamide A, and cytotoxic marine natural products. He also explores combinatorial libraries of biomimetic compounds (nucleosides, azacarbohydrates) for high-throughput screening. Key Projects : His lab investigates antifungal agents targeting chitin synthase, endotoxin sequestration for septic shock, and proteasome inhibition for cancer therapy. Notable contributions include synthetic routes to Jaspine B and structural studies of polyoxamic acid. Publications : Recent work includes stereoselective iminosugar synthesis (2025), SAR analyses of lipopeptides (2010), and neurochemical studies of enantiomers (2016). Over 100 publications span medicinal chemistry, organic synthesis, and drug discovery. Awards & Recognition : While no specific awards are listed, his contributions to antibiotic design and synthetic methodology reflect sustained excellence in the field. Current Activity : Not currently accepting students/postdoctoral fellows, but actively engaged in grant-funded research projects focused on antifungal agents and combinatorial chemistry.

• Medicinal Chemistry
• Synthetic Organic Chemistry
• Chemical Biology
• +۶ مورد دیگر

Jonathan Ellman is the Eugene Higgins Professor of Chemistry and Professor of Pharmacology at Yale University, with joint appointments in the Department of Chemistry and the Department of Pharmacology at the Yale School of Medicine. He is also affiliated with the Yale Cancer Center and the Developmental Therapeutics program. Education: PhD, Chemistry, Harvard University (1989) BS, Chemistry, MIT (1984) NSF Postdoctoral Fellow, University of California at Berkeley (1992) Dr. Ellman's research lies at the intersection of synthetic organic chemistry and biomedical science, focusing on the development of novel synthetic methodologies and their application to drug discovery. His work emphasizes catalysis, particularly in C–H activation and enantioselective synthesis, with a strong interest in sulfur-containing compounds such as sulfoximines and sulfilimines as bioactive motifs. His lab has pioneered methods for constructing complex amine and amide architectures with quaternary centers, which are valuable in medicinal chemistry. A recent focus includes targeting opioid receptors for pain therapeutics with reduced side effects. His research has led to over 350 publications and significant contributions to chemical biology and pharmaceutical sciences. His recent publications reveal a consistent focus on catalytic methodologies, sulfur chemistry, and computational drug design, particularly in targeting opioid receptors. Themes include enantioselective synthesis, C–H functionalization, and the exploration of underutilized heteroatom-containing functional groups in drug discovery. Scientific Awards and Honors: Member, American Academy of Arts and Sciences (2016) Yale Dylan Hixon ’88 Prize for Teaching Excellence in the Natural Sciences (2016) Herbert C. Brown Award for Creative Research in Synthetic Methods (2012) GlaxoSmithKline Chemistry Scholar Award (2010) Pedler Award, Royal Society of Chemistry (2010) Dr. Ellman has trained numerous researchers and maintains a highly collaborative research program, evidenced by frequent co-authorship with colleagues across Yale. His lab, accessible via ellman.chem.yale.edu , is part of Yale’s broader research ecosystem in chemical biology and therapeutics. He has received continuous grant support, particularly in the areas of synthetic methods development and translational chemical biology, although specific grants are not detailed in the text.

Alistair Sterlingمشاهده پروفایل

استادیار

• Physical organic chemistry
• Computational chemistry
• Chemical bonding
• +۳ مورد دیگر

Alistair Sterling is an Assistant Professor in the Department of Chemistry & Biochemistry at the University of Texas at Dallas (UTD), affiliated with the School of Natural Sciences and Mathematics. His research integrates computational modeling, theoretical physical organic chemistry, and electronic structure theory to study chemical reactivity, particularly in catalysis, molecular editing, and polymer upcycling. Sterling leads the Sterling Lab, emphasizing interdisciplinary collaboration with synthetic chemists and fostering skills in reaction mechanism analysis, coding, and scientific communication. He actively engages in outreach to promote public understanding of chemistry. Education includes a DPhil in Organic Chemistry (University of Oxford, 2021), an MChem in Chemistry (University of Oxford, 2017), and postdoctoral fellowships at Lawrence Berkeley National Lab and UC Berkeley. He holds the EPSRC Doctoral Prize Fellowship (2021). Research focuses on understanding chemical bonding and reactivity through computational tools, with applications in drug discovery and sustainable materials. Key themes include delocalization-enabled reactions, node-induced electron confinement, and strain-release mechanisms. The lab develops novel synthetic methods for creating complex molecules with pharmaceutical relevance, such as meta-substituted arene bioisosteres. Notable awards include the Global Young Scientists Summit (2021), Young Modellers' Forum Best Talk Prize (2019), and multiple University of Oxford scholarships. His work bridges theory and experiment, aiming to advance both fundamental understanding and practical innovations in chemistry.

Patrick J. Walshمشاهده پروفایل

استاد

• Catalysis
• Organic Chemistry
• Inorganic Chemistry
• +۷ مورد دیگر

Patrick J. Walsh is the Rhodes-Thompson Professor of Chemistry at the University of Pennsylvania’s College of Arts & Sciences. He leads the Walsh Group, focusing on catalytic methodologies and synthetic chemistry with an emphasis on merging organic/inorganic synthesis and exploring unusual reactivity. His educational background includes a B.A. in Chemistry from UC San Diego (1986), a Ph.D. in Chemistry from UC Berkeley (1991), and a NSF Postdoctoral Fellowship at The Scripps Research Institute (1991–1994). His research interests span catalysis, radical chemistry, and transition metal systems, with key projects involving cation-pi interactions for C-H activation, super electron-donor (SED) 2-azaallyl anions, and photoredox-driven reactions. The group also develops pharmaceutical analogs like bioisosteric BCP compounds and explores transition metal-free syntheses for complex molecules. Recent publications highlight advancements in Ce(III) photoredox systems, Smiles rearrangement applications, and nickel-catalyzed enantioselective reactions. The work demonstrates a focus on sustainable catalytic strategies, mechanistic innovation, and novel compound construction. No scientific awards are explicitly listed in the provided texts. Professor Walsh’s advising spans doctoral, master’s, and undergraduate students, contributing to lab efforts in catalysis and organic synthesis. His team collaborates on diverse projects, including molecular glassformer design and radical relay pathways. Labs/teams: The Walsh Group at Penn actively researches in the areas of synthetic chemistry, catalysis, and radical-mediated reactions. The group emphasizes interdisciplinary approaches and includes visiting scholars alongside traditional academic trainees.

Mahesh Lakshmanمشاهده پروفایل

استاد

• Organic Chemistry
• Nucleoside Chemistry
• Catalysis
• +۳ مورد دیگر

Mahesh Lakshman is a Professor in the Department of Chemistry and Biochemistry at the City College of New York (CUNY). His research focuses on nucleoside chemistry, catalytic methodologies, and the synthesis of novel organic compounds with applications in medicinal chemistry and drug development. He has contributed extensively to the development of new synthetic routes for modifying nucleosides, including approaches for functionalizing purine and pyrimidine bases through C-N and C-C bond formation. His expertise includes metal-catalyzed cross-coupling reactions, directed arylation, and the use of hypervalent iodine reagents. He has explored catalytic systems for reducing organic compounds without external hydrogen gas, advancing green chemistry practices. His work spans nucleoside analogs for antiviral therapies (e.g., molnupiravir) and peptidomimetics based on saturated azaheterocycles. Publications highlight his focus on mechanistic studies, with recent work addressing aroylation of purine nucleosides and the synthesis of carbazolones via nitrene insertion. Despite over 50 publications since 1994, no specific awards or grants are explicitly listed in the provided text. His research often involves collaborations leveraging advanced spectroscopic techniques like NMR for product characterization.

Derek S Tanمشاهده پروفایل

استاد

• Chemical Biology
• Medicinal Chemistry
• Biochemistry
• +۳ مورد دیگر

Derek S. Tan is a Professor in the Department of Biochemistry and Biophysics at Weill Cornell Medical College, holding a Tri-Institutional Professor position effective from 2025. His research integrates chemical synthesis with biological applications, focusing on drug discovery, enzyme mechanisms, and therapeutic engineering. He maintains an active research program with continuous NIH funding. Education: Ph.D., Harvard University (2000) B.S., Stanford University (1995) Research Focus: Professor Tan's work spans chemical biology, medicinal chemistry, and microbiology. He designs bioactive molecules targeting bacterial permeability, enzyme inhibition, and cellular therapeutics. Key areas include ubiquitin pathway biochemistry, antibiotic development against Mycobacterium tuberculosis and Plasmodium falciparum , and engineered T-cell therapies for cancer. His interdisciplinary approach bridges synthetic chemistry with translational applications. Publication Trends: Recent articles (2021-2024) demonstrate three primary themes: 1) Development of mechanistic probes for enzyme systems (ubiquitin pathway, aminoacyl-tRNA synthetases), 2) Antibacterial/antiparasitic agent design leveraging bacterial permeability studies, and 3) Cellular engineering strategies including CAR-T micropharmacies for targeted drug activation. The work consistently combines synthetic chemistry innovation with biological validation. Grants: As Principal Investigator of the Tri-institutional PhD Program in Chemical Biology (NIH/NIGMS funded), he leads initiatives spanning 2020-2025 and 2025-2030. This underscores sustained commitment to interdisciplinary training at the chemistry-biology interface.

Michael Willisمشاهده پروفایل

استاد

• Organic Synthesis
• Catalysis
• Sulfur Functional Groups
• +۴ مورد دیگر

Michael Willis is Professor of Chemistry at the University of Oxford and Fellow of Lincoln College, leading the Willis Research Group with expertise in catalytic organic synthesis. His work bridges academic innovation and industrial pharmaceutical applications through novel sulfur chemistry methodologies. His educational trajectory includes: Undergraduate studies at Imperial College London PhD at University of Cambridge under Professor Steve Ley Postdoctoral research at Harvard University with Professor David Evans Research centers on catalytic sulfur functionalization, particularly using DABSO as a sulfur dioxide surrogate to develop sulfonamide/sulfonimidamide synthesis routes. His group pioneers enantioselective desymmetrization methods and heterocyclic cross-coupling techniques, emphasizing industrial applicability in drug discovery. Key themes include energy-efficient catalysis and sustainable chemistry approaches to complex molecule synthesis. Analysis of recent publications (2021-2023) reveals sustained innovation in sulfur reagent development, with increasing focus on photocatalysis and radical-based transformations for sulfonamide diversification. The work demonstrates strategic progression from fundamental reagent discovery (DABSO) to complex target synthesis with pharmaceutical relevance. Award recognition includes: 2015 Pfizer, AstraZeneca, Syngenta Process Chemistry Research Award 2014 Royal Society of Chemistry Catalysis in Organic Chemistry Award 2008 AstraZeneca Award in Synthetic Organic Chemistry The Willis Group maintains active pharmaceutical industry collaborations while developing next-generation catalytic methods. Current projects focus on expanding sulfur pharmacophore applications and improving synthetic efficiency for agrochemical targets through novel catalytic manifolds.

• Medicinal Chemistry
• Chemical Biology
• Organic Synthesis
• +۳ مورد دیگر

Wei Shi is an Associate Professor of Chemistry (Organic) at Ball State University’s College of Sciences and Humanities, Department of Chemistry. He joined the institution in 2019, specializing in teaching Organic Chemistry and conducting research in Medicinal Chemistry, Chemical Biology, and Organic Synthesis. His research focuses on designing chemical probes derived from natural products to understand small molecule regulation of macro-biomolecules for disease treatment. Education: B.Sc. in Electrochemistry from Shanghai Jiao Tong University (China), M.Sc. in Bioorganic Chemistry from East China University of Science & Technology (China), Ph.D. in Chemistry from the University of Alberta (Canada), and postdoctoral training at Johns Hopkins School of Medicine (USA). Research Interests: Explores the pharmaceutical potential of bioactive natural products, particularly glycoconjugates, aiming to design novel drug candidates with enhanced therapeutic profiles. Key projects include studying ipomoeassin F’s mechanism of action as an ER translocon inhibitor and developing itraconazole analogs for antiangiogenic and anticancer applications. Selected Publications: Over 20 peer-reviewed articles, including landmark studies on ipomoeassin F’s Sec61α binding, itraconazole’s dual targeting of NPC1/VDAC1, and structural analog design. Recent work highlights Sec61 translocon inhibition mechanisms in Mycobacterium ulcerans pathogenesis and ER stress response modulation in cancer cells. Labs/Teams: Director of the Shi Research Group , focusing on natural product-inspired drug discovery and chemical biology.

Helen Sneddonمشاهده پروفایل

استاد

• Sustainable Chemistry
• Green Chemistry
• Renewable Chemicals
• +۳ مورد دیگر

Professor Helen Sneddon is a Professor of Sustainable Chemistry and Director of the Green Chemistry Centre of Excellence (GCCE) at the University of York. She co-directs two Centres for Doctoral Training: Process Industries: Net Zero (PINZ CDT) with Newcastle University and Chemical Synthesis for a Healthy Planet (CSHP CDT) with the University of Oxford. Her research focuses on four core themes: renewable feedstocks, green synthesis, sustainable technologies, and design for sustainable reuse/degradation/recovery. Her group explores biobased monomer production, solvent optimization via Design of Experiments, greener peptide synthesis methods, and halogen bond alternatives in pharmaceuticals. Collaborations include industry partners Syngenta and Synthomer. Key publications include advancements in reaction optimization (2024) and sustainable peptide synthesis (2017). Research training involves supervising PhD students in areas like trifluoromethyl bioisosteres, bio-based polymers, and solvent safety alternatives. Technical support is provided by team members like Emma Dux. Professional experience includes leadership in green chemistry education and industrial partnerships.