جست‌وجوی استاد و پژوهشگر

• Autoimmunity
• Systemic Lupus Erythematosus
• Pathology
• +۴ مورد دیگر

Dr. Huu Matthew Nguyen is a medical researcher and academic at the University of New South Wales, School of Medical Sciences. With qualifications including a Distinction in Bachelor of Medical Science, First Class Honors with Medal in Bachelor of Science, Distinction in Doctor of Medicine, and Associate Fellow of the Higher Education Academy, he has established himself as a specialist in autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), pathology, and immunology. His research focuses on the complex interplay between autoimmune conditions, fatigue mechanisms, and quality of life assessment in patients with SLE. Dr. Nguyen has made significant contributions to understanding comorbid conditions like fibromyalgia in SLE patients, vitamin D and iron status in disease activity, and novel manifestations of autoimmune disorders. His work shows a strong emphasis on patient-centered outcomes and the development of clinical tools for better diagnosis and management of autoimmune conditions. Dr. Nguyen's publications reveal an interdisciplinary approach that bridges pathology, biochemistry, molecular biology, immunology, and clinical rheumatology to advance understanding of complex autoimmune conditions. His research spans from genetic neurodevelopmental disorders to clinical applications in rheumatology and patient care. 2020 School of Medical Sciences Student Demonstrator of the Year in Pathology 2018 University Medal for Medical Science 2017 Winifred Dickes Rost School of Medical Sciences Honours Prize 2017 Dean's Honours Year Scholarship Multiple Dean's List recognitions for Academic Excellence (2014-2015) Dr. Nguyen actively contributes to medical education at UNSW, demonstrating excellence in teaching as recognized by his Student Demonstrator of the Year award. His research portfolio includes investigations into rare autoimmune presentations, biomarker research, and developing better clinical assessment tools for complex rheumatic diseases.

Simon T. Schäferمشاهده پروفایل

استاد

• Stem Cell Biology
• Neuroscience
• Mental Health Research
• +۳ مورد دیگر

Prof. Dr. Simon T. Schäfer is a Professor at the Technical University of Munich (TUM) , leading the Advanced Organoid Technologies for Mental Health Research group within the TUM School of Medicine and Health . His research focuses on developing stem cell-based organoid models to study neurodevelopmental and neurodegenerative disorders, with applications in personalized medicine and tissue repair strategies. He holds the Rudolf Mössbauer Professorship and is part of the Center for Organoid Systems (COS). Education: Studied medicine and biomedical sciences in Greifswald (Germany) and San Diego (USA) Doctorate followed by postdoctoral research at the Salk Institute for Biological Studies, La Jolla, CA Research Interests: Stem cell biology and organoid engineering Neurodevelopmental disorders (autism, macrocephaly) Neurodegenerative diseases (Parkinson's, Alzheimer's) Microglia biology and neuroimmune interactions Therapeutic strategies for brain repair Scientific Awards: Early Excellence Academy Member (2023) NARSAD Young Investigator Award (2019 & 2022) DFG Research Fellowship (2016) James S. McDonnell Foundation Fellowship (2015) Advisees/Grants: Leads the COS lab with his research group Oversees translational projects linking organoid models to clinical applications Labs/Teams: Center for Organoid Systems (COS) Collaborations with Salk Institute and international stem cell networks

Simone Maderمشاهده پروفایل

استادیار

• Neuroimmunology
• Autoantibodies
• CNS Demyelinating Diseases
• +۷ مورد دیگر

PD Dr. Simone Mader is a Junior Group Leader and neuroimmunologist at the Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, Ludwig-Maximilians University Munich. She is also an Instructor at the same institute and a full member of the Graduate School of Systemic Neuroscience (GSN). Her research is centered on CNS-reactive autoantibodies in autoimmune neurological disorders such as Neuromyelitis Optica Spectrum Disorder (NMOSD), multiple sclerosis, and cerebellar ataxia. Education: Bachelor in Biology, Leopold-Franzens University, Innsbruck (2001–2005) Master in Molecular Biology, Leopold-Franzens University (2005–2007) PhD in Neurology, Medical University of Innsbruck (2008–2011) Venia Legendi (Habilitation) awarded in 2022 Her research focuses on identifying novel CNS-reactive autoantibodies and understanding their role in neuronal and glial dysfunction. She employs advanced techniques like single-cell sorting, immunoprecipitation, and live neuronal cultures. Her work bridges mechanistic insights with clinical applications, aiming at biomarker discovery and therapeutic interventions. Analysis of her recent publications reveals a strong emphasis on autoantibody pathogenesis in demyelinating diseases, B cell biology, maternal antibody transfer, and novel antigen discovery. Her work frequently involves collaborations with clinical teams and international research groups. Scientific Awards: Early Career Investigator Award, National Ataxia Foundation (2023) Eureka Grant, The Guthy-Jackson Charitable Foundation (2022) Young Investigator Fund, Schering Stiftung (2019) Autism Society Award for best manuscript (2017) Ursula & Fritz Melchers PhD Award (2012) Dr. Mader has successfully secured funding from diverse sources including Novartis, Else Kröner Fresenius Stiftung, and the Guthy-Jackson Foundation. She mentors several PhD and master’s students and leads an active research team. Her lab collaborates closely with AG Meinl and clinical neuroimmunology groups, contributing significantly to the understanding of antibody-mediated CNS diseases.

Jim Bodfishمشاهده پروفایل

استاد

• Autism Spectrum Disorders
• Behavioral Neuroscience
• Developmental Disabilities
• +۷ مورد دیگر

Jim Bodfish is a Professor and holds the Thomas L. and Jane Wilkerson Yount Endowed Chair at Vanderbilt University School of Medicine. He is affiliated with the Department of Hearing and Speech Sciences and conducts research on autism spectrum disorders, particularly severe and treatment-resistant forms. His work integrates clinical practice with translational research to understand the neuro-behavioral underpinnings of poor developmental outcomes in autism. Education: B.S., 1983, University of New Haven, CT M.S., 1985, University of Alabama, AL Ph.D., 1986, University of Alabama, AL Post-Doctoral Fellowship, 1987, Eunice Kennedy-Shriver Center for Developmental Disabilities; Harvard Medical School & Massachusetts General Hospital, MA Dr. Bodfish's research focuses on the pathogenesis and treatment of autism, especially complex presentations involving behavior and mood problems, cognitive deficits, sensory and motor disorders, and genetic conditions. His lab employs behavioral neuroscience approaches such as naturalistic behavioral observation, eye-tracking, sensory psychophysics, kinematics, pupilometry, facial action coding, electrophysiology, and functional neuroimaging. The goal is to identify measurable markers of adverse developmental trajectories and develop novel interventions. Although no publications are listed in the provided text, his methodological diversity suggests strong interdisciplinary research spanning neuroscience, psychology, and clinical intervention development. Dr. Bodfish is actively involved in both research and clinical service delivery for autism. His lab fosters collaboration between clinicians, basic scientists, and applied researchers. He is engaged in translational projects including outcome measure development, behavioral treatment design, and preclinical behavioral assays for drug discovery. While specific grants and advisees are not mentioned, his work appears to be supported by his endowed chair and institutional affiliations. He leads a multidisciplinary research team focused on autism pathogenesis and intervention. The Bodfish Lab emphasizes an equal partnership among clinicians and researchers, utilizing dense observational methods and advanced psychophysiological tools to study autism across multiple levels of analysis—from behavior to brain function.

Jin Heمشاهده پروفایل

دانشیار

• Epigenetics
• Gene Regulation
• Cancer Biology
• +۳ مورد دیگر

Jin He is an Associate Professor in the Department of Biochemistry and Molecular Biology at Michigan State University. His research focuses on epigenetic mechanisms in gene regulation, particularly during development and in diseases like cancer and neurodevelopmental disorders. The He lab investigates dynamic epigenetic modifications at gene regulatory elements and their roles in lineage specification, cell fate determination, and tumorigenesis. Key research areas include the functional roles of histone methyltransferases (e.g., ASH1L, SMYD5) and demethylases (e.g., KDM2B, KDM6B) in neural development, autism spectrum disorder (ASD)/intellectual disability (ID), and leukemia. His studies employ mouse models, drug interventions (e.g., vorinostat), and systems biology approaches to dissect epigenetic pathways. Publications highlight interdisciplinary work in neuroscience, stem cell biology, and oncology, with a focus on translating epigenetic insights into therapeutic strategies. Collaborative projects include longitudinal omics studies and drug efficacy testing in disease models.

George Miasمشاهده پروفایل

دانشیار

• Precision Medicine
• Omics Technologies
• Systems Biology
• +۵ مورد دیگر

George Mias is an Associate Professor in the Department of Biochemistry and Molecular Biology at Michigan State University (MSU). He also serves as Chief of the Systems Biology Division within the Institute for Quantitative Health Science and Engineering. His research integrates omics technologies to advance precision medicine, focusing on transitioning physiological states from health to diseases such as leukemia and immune disorders. Dr. Mias holds a Ph.D. in Physics from Yale University and completed postdoctoral training in Genetics at Stanford University. His work emphasizes interdisciplinary approaches combining experimental and computational methods, utilizing software like MathIOmica for omics analysis. Key research areas include space health monitoring, AI-driven labs, and longitudinal molecular signatures for disease prediction. His studies bridge fields like systems biology, epigenetics, and computational modeling to address challenges in personalized healthcare and deep space exploration. Notable achievements include developing methodologies for multi-omics data integration and uncovering mechanisms in leukemogenesis and neural stem cell dysfunction. His recent work explores astronaut health dynamics and AI applications in biomedical research, reflecting a commitment to advancing both clinical and exploratory science.

Carmen Marsitمشاهده پروفایل

استاد

• Maternal and Child Health Epidemiology
• Epigenetics
• Genomics
• +۶ مورد دیگر

Dr. Carmen Marsit is the Rollins Distinguished Professor of Research and Executive Associate Dean for Faculty Affairs and Research Strategy at Emory University's Rollins School of Public Health. He leads the NIEHS-funded HERCULES Exposome Research Center and the T32 Training Program in Environmental Health Sciences. His work focuses on molecular mechanisms linking environmental exposures to human diseases, particularly cancer, adverse pregnancy outcomes, and childhood disorders, using interdisciplinary approaches including epigenomics and '-omics' technologies. Marsit earned his Ph.D. in Biological Sciences in Public Health from Harvard University and held prior faculty positions at Brown University and Dartmouth Geisel School of Medicine. Education: B.S., Lafayette College; Ph.D., Harvard University. Research Interests: Environmental epigenetics, placental biology, and the exposome's role in health disparities. Current projects include the Rhode Island Child Health Study (RICHS), examining placental impacts on child health. Grants & Awards: Multiple NIH R01 grants, leadership in NIEHS/EPA Children's Environmental Health Centers, and international advisory roles. His publications emphasize environmental exposures' molecular pathways, with recent work on pyrethroid pesticide effects, PM2.5 metabolism, and epigenetic aging in child health outcomes. Marsit collaborates globally on exposome research and trains future environmental health scientists through NIH-funded programs.

Nikhil Paiمشاهده پروفایل

دانشیار بالینی

• Pediatric Gastroenterology
• Microbiome
• Nutritional Science
• +۷ مورد دیگر

Dr. Nikhil Pai is an Associate Clinical Professor of Pediatrics at McMaster University and a Staff Physician in the Division of Pediatric Gastroenterology at McMaster Children’s Hospital. He serves as Medical Lead of the Complex Pediatric Nutrition Service and Pediatric Intestinal Failure program. From July 2024, he will join the Perelman School of Medicine at the University of Pennsylvania as an Associate Professor of Pediatrics and Staff Physician at the Children’s Hospital of Philadelphia while maintaining a part-time Assistant Professor appointment at McMaster. Education: B.Sc, University of Western Ontario (2001–2004) M.D, McMaster University (2004–2007) Pediatrics Residency, Hospital for Sick Children/University of Toronto (2007–2011) Pediatric Gastroenterology Fellowship, Boston Children's Hospital/Harvard Medical School (2011–2014) Postdoctoral Research: Intestinal Microbiome, Massachusetts General Hospital/Harvard University (2012–2014) Research Focus: Dr. Pai specializes in pediatric gastroenterology with emphasis on nutritional science, microbial therapeutics, and host-microbiome interactions. His work includes pioneering clinical trials on fecal microbiota transplantation (FMT) for pediatric inflammatory bowel disease (IBD), and leadership of multicenter studies (PediFeTCh, PediCRaFT, FIND trials) examining microbial/nutritional interventions in ulcerative colitis, Crohn's disease, and fatty liver disease. His research bridges basic science and clinical applications in gut microbiome modulation. Publication Trends: His 15 most recent articles (2021–2025) focus on FMT clinical outcomes, urine metabolomics for IBD diagnosis, therapeutic nutrition, gut-brain axis disorders, and pediatric liver disease management, reflecting translational research bridging microbiome science and clinical gastroenterology. Awards: 2023 ASPEN Stanley J. Dudrick Research Award 2024 Canadian Nutrition Society Young Investigator Award Ontario Innovation Award Academic Activities: Dr. Pai mentors medical students, residents, and fellows, and has secured >$3.98M in research funding (CIHR/non-profit grants). He leads the Pai Lab and is Associate Member of McMaster's Farncombe Institute and MODR Centre. Administrative roles include co-chairing hospital nutrition committees and advising Health Canada on FMT therapeutics.

• Pediatric Genetics
• Adult and Prenatal Genetics
• Congenital Anomaly Syndromes
• +۳ مورد دیگر

Jacob Hogue, M.D., is a Colonel in the U.S. Army and currently serves as Chief of the Department of Clinical Investigation and Chief of Genetics at Madigan Army Medical Center in Tacoma, WA. He also chairs the Bioethics Board and Performance Improvement Committee. Education: Uniformed Services University of the Health Sciences (M.D., 2001-2005), University of California, San Francisco (Medical Genetics Residency, 2008-2011), and Valparaiso University (B.S. in Chemistry and Biology, 1997-2001). His research focuses on the etiology and management of genetic disorders such as multiple congenital anomaly syndromes, autism, and intellectual disability, particularly those with military relevance. He is the sole Medical Geneticist on the U.S. West Coast, providing clinical care for genetic conditions across all age groups. The most recent 10 publications span topics including battlefield medicine, RASopathies, chromosomal mosaicism, and craniofacial genetic syndromes. Notable themes include pandemic response strategies, protein N-terminal acetylation mechanisms, and the clinical implications of GLIS3 mutations. Throughout his career, Dr. Hogue has led key institutional bodies such as the Madigan Army Medical Center Institutional Review Board (2016-2022) and served as Associate Program Director for Pediatrics Residency (2015-2021). He has participated in military operations including Operation Border Security (2018) and Operation Enduring Freedom (2012). Dr. Hogue oversees the Madigan Department of Clinical Investigation, managing laboratory facilities, research personnel, and scholarly activities. His role includes promoting external funding acquisition and research education for military medical personnel.

Łukasz J Sznajderمشاهده پروفایل

استادیار

• RNA Biology
• Genetic Disorders
• Alternative Splicing
• +۳ مورد دیگر

Łukasz J Sznajder is an Assistant Professor in the Department of Chemistry and Biochemistry at the University of Nevada, Las Vegas , focusing on RNA biology and its role in genetic disorders. His research primarily investigates the molecular mechanisms behind alternative splicing dysregulation in diseases such as myotonic dystrophy. CURRENT ROLE: Assistant Professor AFFILIATION: UNLV Department of Chemistry and Biochemistry CONTACT: lukasz.sznajder@unlv.edu Research Interests revolve around: MBNL protein function in RNA splicing Toxic RNA accumulation in repeat expansion diseases Neurodevelopmental consequences of RNA misprocessing Therapeutic strategies using CRISPR/Cas9 systems Cell-type-specific splicing defects RNA metabolism dynamics in neuromuscular disorders Scientific Trends from Publications (2018-2025) reveal: Central role of MBNL sequestration in RNA mis-splicing Systemic effects of repeat expansions on multiple organs Emerging therapeutic approaches targeting RNA toxicity Intersection of developmental gene regulation and disease Structural context dependency of splicing factors Translational relevance of mouse models in human disease

• Microbiology
• Immunology
• Neuroimmune Disease
• +۳ مورد دیگر

Vincent Lombardi, Ph.D. , is a Research Associate Professor in the Department of Microbiology and Immunology at the University of Nevada, Reno. He has previously held adjunct professorships in Pathology and Biochemistry at the same institution and served as Director of Research at the Nevada Center for Biomedical Research. Education: Ph.D. in Biochemistry, University of Nevada, Reno (2001–2007) B.A. in Science, Sierra Nevada College, Incline Village, NV (1990–1995) Research Interests: Dr. Lombardi's research focuses on understanding the role of innate immunity in the gut-brain axis, particularly in neuroimmune diseases such as Alzheimer's disease and myalgic encephalomyelitis. His lab investigates secretory IgA's impact on gut microbiota, JAK activation in lymphocytes, Aryl hydrocarbon receptor agonists, and plasmacytoid dendritic cells in neuroimmune pathology. Publications: His recent work spans microbiology, immunology, and neuroimmune disease, with a strong emphasis on translational applications. Key themes include cytokine profiling, genomic associations in chronic illnesses, and therapeutic modulation of the gut-brain axis. Lab Members: Current: Vincent C. Lombardi, Katherine Gabrie Past: Shanti Rawat, Sarah Saxe, Peter Asimenios, Griffen Kutler-Dodd, Krishnamurthy Subramanian

• Autism Research
• Neurodevelopmental Disorders
• Brain Development
• +۵ مورد دیگر

Bruce K. Krueger serves as Professor of Pharmacology & Physiology with a secondary appointment in Psychiatry at the University of Maryland School of Medicine. He holds the administrative role of Research Ombudsperson at UMB and maintains an active laboratory funded by the National Institute of Environmental Health Sciences (NIH). His educational background includes: Ph.D. in Molecular Biophysics and Biochemistry from Yale University (1975) Postdoctoral Fellowship in Pharmacology at Yale University (1975-76) Postdoctoral Fellowship in Physiology at Washington University School of Medicine (1976-79) Dr. Krueger's research centers on cellular and molecular mechanisms of brain development underlying autism and neurodevelopmental disorders. His laboratory investigates how prenatal environmental exposures like valproic acid (VPA) interact with genetic predispositions to cause autistic behaviors, utilizing transcriptomic and epigenetic approaches. Current work focuses on gene-environment interactions in Down syndrome, leveraging RNAseq, snRNAseq, and recombinant DNA technology to map developmental disruptions in neurogenesis, axon growth, and synaptogenesis. His publication record demonstrates consistent focus on autism pathogenesis, with recent work analyzing VPA-induced transcriptome alterations and BDNF dysregulation. Key methodologies include quantitative PCR, in situ hybridization, confocal microscopy, and behavioral assays in murine models. Scientific recognition includes: Alfred P. Sloan Foundation Fellowship (1979) Guggenheim Fellowship (1991) Fogarty International Fellowship (1991) Dr. Krueger has mentored five doctoral students to completion, with advisees now holding prominent positions at NIH, Children's National Medical Center, and EMBL's European Bioinformatics Institute. His laboratory actively recruits GPILS graduate students in Neuroscience and Molecular Medicine programs, emphasizing translational research connecting environmental toxicology to neurodevelopmental outcomes.

• Medical Biology
• Oncology
• Epigenetics
• +۳ مورد دیگر

Dr. Orkun Gürbüz serves as Assistant Professor in the Department of Medical Services and Techniques at Istinye University's Vocational School of Health Care Services. A graduate of Istanbul University Oncology Institute (Department of Basic Oncology) for both master's and doctorate degrees following undergraduate completion in 2007, he maintains active research in medical biology with translational oncology focus. His academic trajectory includes: Undergraduate completion: 2007 Graduate studies: Department of Basic Oncology, Istanbul University Oncology Institute Current position: Assistant Professor, Medical Services and Techniques Department Research centers on molecular oncology mechanisms with dual emphases: cancer epigenetics (RB1 methylation in retinoblastoma, FOXO3a dysregulation in leukemias) and emerging neurodevelopmental toxicology (mRNA vaccine impacts). His work integrates human tissue analysis, animal models, and molecular techniques to investigate tumorigenesis pathways and environmental exposures. Recent publications (2021-2024) reveal increasing diversification from pure oncology into neurodevelopmental fields while maintaining strong epigenetic focus. The 2024 autism-vaccine study represents significant methodological expansion beyond traditional cancer research, indicating growing interdisciplinary approach. Scientific recognition includes: No major awards specified in available materials Consistent publication output in specialized oncology journals Advising and research activities show active mentorship potential through recent publications, though specific student counts aren't documented. His dual expertise in cancer genetics and neurotoxicology creates unique training opportunities in molecular medicine. Lab infrastructure likely includes epigenetic analysis tools and animal facilities supporting his published methodologies.

• Autistic Disorder
• Brain Diseases
• Cardiovascular Diseases
• +۱۲ مورد دیگر

Gianfilippo Coppola, PhD, is an Assistant Professor in the Department of Pathology at Yale School of Medicine. His research integrates computational and systems biology with neuroscience and genetics, focusing on neurodevelopmental disorders and cortical astroglial dynamics. Undergraduate: Chemical Engineering, Universita' di Napoli 'Federico II' PhD: Mechanical Engineering, Yale University His work explores autism spectrum disorders , Tourette syndrome , and stress-induced neuroplasticity using advanced models like 3D organoids and translatomic sequencing . Key publications examine HMGB1 regulation in astrocyte development and ENPP1 deficiency pathways in bone diseases. Recent studies highlight sex differences in cortical astroglia and optogenetic neuroprotection in degenerative models. His interdisciplinary approach bridges computational biology with clinical neuroscience , emphasizing applications in psychiatric and neurodegenerative diseases.

Peter Celecمشاهده پروفایل

استاد

• Extracellular DNA Pathophysiology
• Chronobiology
• Metabolism
• +۴ مورد دیگر

Peter Celec is a Professor at the Institute of Molecular Biomedicine within the Faculty of Medicine at Comenius University in Bratislava, with dual affiliation at the Slovak Academy of Sciences. His research bridges molecular biomedicine and clinical pathology, focusing on mechanistic studies of disease biomarkers and therapeutic targets. His academic credentials include: MD (2003) Dipl. Ing. (2004) PhD (2005) MSc (2006) MPH (2009) Dr. Rer. Nat. (2009) Associate Professor (2013) DSc (2015) Professor (2024) Celec's research centers on extracellular DNA pathophysiology, particularly its role in neutrophil extracellular traps (NETs) formation and clearance across inflammatory conditions including sepsis, rheumatoid arthritis, and chronic kidney disease. His chronobiology work examines testosterone dynamics and hormonal effects on behavior, while metabolic studies investigate cola beverages' physiological impacts using animal models. This multi-system approach integrates molecular techniques with clinical observations to elucidate disease mechanisms. Analysis of his 2020-2025 publications reveals dominant themes in extracellular DNA as both diagnostic biomarker and therapeutic target, with significant contributions to NETs biology across immunology, nephrology, and neuroscience. His work demonstrates translational potential through DNase-based interventions and gut-brain axis investigations, particularly in autism spectrum disorder models. No scientific awards were documented in the source material. Prof. Celec leads an active research group at the Institute of Molecular Biomedicine (contact: +421-2-90119-274, +421-2-90119-350), directing studies on extracellular DNA dynamics in biofluids and disease models. His extensive publication record across high-impact journals indicates sustained research funding, though specific grants were not detailed in the provided information. The laboratory operates across dual locations: the 5th floor of the Pavilion of Medical Sciences at Sasinkova 4 (Comenius University) and the 6th floor of Slovak Academy of Sciences' B block, facilitating collaborative work between academic and national research institutions.