جست‌وجوی استاد و پژوهشگر

• Natural Products Research
• Phytomedicine
• Herbal Product Standardization
• +۷ مورد دیگر

Roles & Affiliations: Ikhlas Khan serves as Director of the National Center for Natural Products Research (NCNPR), Distinguished Professor, and Research Professor of Pharmacognosy at the University of Mississippi's School of Pharmacy. He also leads the FDA Program and coordinates natural products research across multiple initiatives, including the Sino-US TCM Research Center and the Center for Research of Indian Systems of Medicine (CRISM). Education: B.Sc. Chemistry (1980) - Aligarh Muslim University, India M.Sc. Organic Chemistry (1982) - Aligarh Muslim University, India Ph.D. Pharmacy (1987) - Ludwig-Maximilians-Universität, Munich Postdoctoral Studies - Swiss Federal Institute of Technology (ETH), Zurich Research Focus: Dr. Khan specializes in natural products research with emphasis on: Phytomedicine: Standardization of herbal products via analytical fingerprinting, pesticide/herbicide residue analysis, and bioanalytical quality control. Drug Discovery: Isolation of bioactive natural products, development of analytical methods for phytochemical characterization, and chiral separation techniques. Metabolism Studies: Role of metabolism in drug/natural product activity, particularly in aminoquinoline antimalarials. His work bridges academia, industry, and regulatory bodies, shaping policies for botanical supplements. Key Contributions: Over 850 peer-reviewed publications and leadership in high-impact projects like the FDA Center of Excellence. His lab pioneered methods to combat herbal product adulteration and safety issues. Awards & Recognition: UM Distinguished Professor Award (2018) Wiley Award (AOAC International, 2018) Qihuang International Prize (2017) Honoris Causa Doctorate (University of Hamdard, 2012) Labs & Collaborations: Directs the NCNPR, a global leader in natural products research, and collaborates with institutions worldwide. His team develops technologies for herbal product authentication and drug metabolism studies.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +۴ مورد دیگر

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

• Genomics
• Malaria Research
• Parasitology
• +۳ مورد دیگر

David Serre is a Professor in the Department of Microbiology and Immunology at the University of Maryland School of Medicine, with an additional appointment at the Institute for Genome Sciences. His research focuses on developing genomic approaches to study eukaryotic pathogens, particularly Plasmodium vivax, the leading cause of malaria outside Africa. His laboratory investigates parasite responses to antimalarial drugs, host immune responses, and mosquito vector biology using genomic and transcriptomic techniques. Education 1997–2000: Engineering degree in Chemistry, École Nationale Supérieure de Chimie, Montpellier, France 2000–2004: PhD in Biology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany 2004–2007: Postdoctoral fellowship, McGill University and Genome Quebec Innovation Centre, Montreal, Canada Research Focus Dr. Serre’s work integrates genomics to study Plasmodium vivax’s drug resistance, relapse mechanisms, and interactions with hosts and vectors. Key areas include: Genomic assays to characterize parasite drug responses Transcriptomic analysis of host immune responses Genomic studies of Anopheles mosquitoes as malaria vectors Recent Trends in Publications Recent work highlights genomic and transcriptomic approaches to dissect Plasmodium vivax biology, including: Single-cell RNA sequencing to resolve transcript isoforms and stage-specific expression Analysis of relapse dynamics and drug resistance mechanisms Microbiome studies in mosquitoes and environmental contexts Grants & Advising No explicit grants or advisee names are listed in the provided text. Collaborators include institutions like the Max Planck Institute, McGill University, and the Institute for Genome Sciences. Labs & Teams His lab is affiliated with the University of Maryland School of Medicine and the Institute for Genome Sciences, focusing on genomic and molecular approaches to infectious diseases.

William John Mossمشاهده پروفایل

استاد

• Infectious diseases
• Vaccine-preventable diseases
• Infectious disease epidemiology
• +۷ مورد دیگر

William John Moss is a Professor in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health, where he also holds joint appointments in International Health and Molecular Microbiology and Immunology. He serves as Executive Director of the International Vaccine Access Center (IVAC) and Deputy Director at the Johns Hopkins Malaria Research Institute. His work spans multiple centers including the Center for Global Health, Center for Humanitarian Health, and Johns Hopkins Vaccine Initiative. Dr. Moss earned his MD from Columbia University in 1984 and his MPH in 1995. As a pediatrician with subspecialty training in infectious diseases, he has conducted extensive field research across multiple countries including Ethiopia, Kenya, South Africa, Zambia, Zimbabwe and India. His research focuses on the epidemiology and control of childhood infections in resource-poor settings, with particular emphasis on measles-HIV interactions, malaria transmission in southern Africa, serosurveillance for immunization programs, and care of HIV-infected children in rural Zambia. His recent work (2024-2025) demonstrates continued focus on measles epidemiology, malaria transmission dynamics, and vaccine implementation research, with numerous publications examining immunity gaps, human mobility patterns, and malaria vector biology in African settings. Scientific Awards: Wyeth-Lederle Vaccines and Pediatrics Young Investigator Award in Vaccine Development (1999-2001) Gustave J. Martin Innovative Research Fund Fellow (2001) Advising, Mentoring and Teaching Recognition Award (2007-2008) Dr. Moss leads multiple research projects including studies on HIV-infected children's immune reconstitution, malaria transmission dynamics in southern Zambia, and strengthening immunization systems through serosurveillance. His work bridges clinical medicine, epidemiology, and public health policy to address critical challenges in global infectious disease control.

Istvan Albertمشاهده پروفایل

استاد پژوهشی

• Bioinformatics
• Genomics
• Computational Biology
• +۵ مورد دیگر

Istvan Albert is a Research Professor of Bioinformatics at Pennsylvania State University , affiliated with the Department of Biochemistry and Molecular Biology . He leads the Bioinformatics Consulting Center and teaches BMMB 852: Applied Bioinformatics . Research Interests: Specializing in bioinformatics, large-scale biological data analysis, microarray and sequence analysis, scientific programming, algorithm development, and database-driven web development. His work spans gene ontology visualization , RNA-Seq analysis , and coronavirus research . Software Development: Created GeneScape for gene function visualization and bio for bioinformatics workflows. Maintains the Biostar Handbook series and the Biostars Q&A Forum , a leading bioinformatics resource.

• Epidemiology of Birth Defects
• Gene-Environment Interactions in Perinatal Health
• Nutrition and Reproductive Outcomes
• +۴ مورد دیگر

Gary M. Shaw is the Rosemarie Hess Professor and Professor (Research) at Stanford University , with courtesy appointments in the Department of Epidemiology and Population Health and Department of Obstetrics & Gynecology - Maternal Fetal Medicine . He serves as Co-PI of the March of Dimes Prematurity Research Center at Stanford and PI of the California Center for Finding Causes and Preventives of Birth Defects . His research focuses on the Epidemiology of birth defects Gene-environment interactions in perinatal outcomes Nutritional factors in reproductive health . He has developed machine learning approaches for precision parenteral nutrition and predictive models for preterm birth, while investigating persistent metabolomic signatures following hypertensive pregnancy disorders. Shaw's recent work explores Climate change impacts on reproductive health Maternal-fetal immune interactions Epigenetic mechanisms in perinatal disease with applications of multiomics to neonatal intensive care units. As a member of Bio-X and the Maternal & Child Health Research Institute , he contributes to translational research networks while serving as Associate Editor for Birth Defects Research and American Journal of Medical Genetics . He supervises Med Scholar Project student Richard Liang Doctoral co-advisor for Saskia Comess and Richard Liang Master's advisor for Lenae Joe while leading the Division of Neonatology as Associate Chair for Clinical Research (2012-2025). His laboratory work integrates Metabolomic profiling Proteomic analysis Computational modeling Machine learning for biomedical data to advance neonatal care through precision medicine approaches.

Albert M. Berghuisمشاهده پروفایل

استاد

• Antibiotic Resistance
• Structural Biology
• X-ray Crystallography
• +۳ مورد دیگر

Albert M. Berghuis is a Professor in the Department of Biochemistry at McGill University's Faculty of Medicine. His research focuses on structural mechanisms of antibiotic resistance and fungal pathogenesis using advanced techniques including X-ray crystallography, electron microscopy, and computational chemistry. His primary research interests include: Structural basis of antibiotic resistance mechanisms, particularly against aminoglycosides Development of novel antimicrobials through structure-based drug design Structural studies of fungal-specific metabolic pathways for antifungal drug discovery Enzyme mechanisms involving protein-small molecule interactions Analysis of his recent publications reveals a consistent focus on structural elucidation of resistance mechanisms, with particular emphasis on aminoglycoside-modifying enzymes and fungal targets. His work bridges structural biology with therapeutic development, showing strong translational potential in combating antimicrobial resistance. Professor Berghuis maintains the Berghuis Lab with facilities in both the McIntyre Medical Sciences Building and the Francesco Bellini Life Sciences Building. His laboratory employs integrated structural biology approaches to tackle pressing problems in infectious disease treatment.

Shutao Maمشاهده پروفایل

استاد

• Medicinal Chemistry
• Antibacterial Drug Discovery
• Antibiotic Resistance
• +۳ مورد دیگر

Shutao Ma is a Professor and Doctoral Supervisor at Shandong University's School of Pharmaceutical Sciences, serving as Director of the Department of Medicinal Chemistry since 2009. He has received the Special Government Allowance from China's State Council since 2002 and the seventh youth award of Shandong province for his contributions to medicinal chemistry. His academic credentials include: Ph.D. in Pharmaceutical Sciences, Shandong University (2004-2007) M.Sc. in Pharmaceutical Sciences, Shandong Medical University (1988-1991) B.Sc. in Pharmaceutical Sciences, Shandong Medical University (1981-1986) Professor Ma's research pioneers innovative strategies against antibiotic-resistant bacteria through three interconnected pillars: 1) Designing FtsZ/AcrB-targeted small molecules to disrupt bacterial cell division and efflux mechanisms; 2) Structural optimization of macrolides, glycopeptides, and lipopeptides to overcome resistance; 3) Total synthesis and mechanistic studies of marine-derived antibacterial natural products. His work bridges synthetic chemistry with microbiological validation to develop next-generation antimicrobials. Analysis of his 15 most recent publications (2014-2016) reveals a dominant focus on antibacterial drug discovery (87% of works), particularly FtsZ inhibitors (33%) and macrolide derivatives (27%). Emerging themes include quorum sensing modulation (7%) and antiviral/anticancer applications (13%), demonstrating strategic expansion while maintaining core expertise in resistance mechanisms. His scientific recognition includes: First prize of Shandong science and technology progress award (2000) Special government allowance from the State Council (2002) The seventh youth awards of Shandong province (2002) As a Doctoral Supervisor, Professor Ma mentors the next generation of medicinal chemists while directing a robust research program funded by 12 major grants. His National Natural Science Foundation portfolio (2004-2020) spans antibacterial discovery, while Shandong Provincial grants (2006-2017) and China-Australia collaborations (2014-2017) support translational development of resistance-breaking agents. Leading the Department of Medicinal Chemistry, he oversees a multidisciplinary team integrating synthetic chemistry, microbiology, and computational modeling to advance antibacterial drug candidates from concept to preclinical validation, with particular emphasis on FtsZ-targeted therapeutics and macrolide engineering.

Anne Berit C. Samuelsenمشاهده پروفایل

دانشیار

• Polysaccharide Chemistry
• Pharmacognosy
• Carbohydrate Polymers
• +۴ مورد دیگر

Anne Berit C. Samuelsen serves as Associate Professor at the Department of Pharmacy, University of Oslo, where she also holds the position of Head of Education. Her academic foundation includes a Cand.pharm. degree and Dr.scient. doctorate, establishing her expertise in pharmaceutical sciences. Her research centers on polysaccharides from natural sources—particularly higher plants, cereals, and fungi (Basidiomycota)—with specialized focus on β-glucans. Key interests include carbohydrate chemistry, pharmacognosy, and the development of biopolymer-based pharmaceutical applications. Her work bridges fundamental structural characterization with practical drug delivery solutions, notably through liposome coating technologies and immunomodulatory compound development. Recent publications reveal a strong trajectory in fungal polysaccharide research, particularly with Pleurotus eryngii and Albatrellus ovinus species. Her team employs advanced techniques like diffusion-ordered NMR spectroscopy to analyze polysaccharide structures while investigating biological activities related to immune receptor binding (Dectin-1, Toll-like receptors) and therapeutic applications. This work demonstrates consistent output in high-impact journals including Carbohydrate Polymers and ACS Applied Bio Materials . She actively contributes to academic instruction through courses such as FARM1150 (Pharmaceutically Oriented Biochemistry), FARM3100 (Pharmacognosy), and FARM5200 (Use of Biopolymers in Pharmaceuticals). Her leadership extends to the Bioactive Natural Substances and Health Effects (BioNatH) research group and the Glyconor Consortium, where she investigates natural product applications for health improvement.

Ananias A. Escalanteمشاهده پروفایل

استاد

• Evolutionary Genomics
• Malaria Research
• Population Genetics
• +۳ مورد دیگر

Ananias A. Escalante is a Professor in the Department of Biology at Temple University's College of Science and Technology, and a core faculty member of the Institute for Genomics and Evolutionary Medicine (iGEM). He holds a PhD in Biology from the University of California, Irvine (1995), and has held roles at the CDC (1995–2005) and Arizona State University (2005–2015). His research integrates population genetics with epidemiology, focusing on malaria parasites' evolution, drug resistance mechanisms, and biodiversity. Key areas include Plasmodium falciparum resistance mutations, primate malaria origins, and molecular tools for surveillance. Education: PhD in Biology, University of California, Irvine (1995) MSc in Ecology, Universidad Simón Bolívar, Venezuela Bachelor's Degree in Biology, Universidad Simón Bolívar, Venezuela Research interests span evolutionary genomics, malaria parasite diversity, and the application of genomic tools to epidemiology. He investigates how genetic diversity in parasites influences drug resistance and transmission dynamics, with a focus on nonhuman primate malaria as a model for human malaria origins. His work includes phylogenetic studies of Plasmodium species and the development of mitochondrial genome protocols for pathogen analysis. Notable contributions include studies on Plasmodium vivax population genetics in the Americas, the impact of drug resistance mutations (e.g., pfhrp2/pfhrp3 deletions), and the molecular characterization of novel malaria parasites in reptiles and birds. He collaborates on initiatives like the Amazonian International Center of Excellence for Malaria Research. Advising and grants: While specific student names aren’t listed, his research team likely includes graduate students focused on evolutionary parasitology. Grants support projects on malaria genomics and vector ecology. He leads Temple’s iGEM lab, advancing interdisciplinary research in genomics and evolutionary medicine. Labs/Teams: Core faculty at Temple’s Institute for Genomics and Evolutionary Medicine (iGEM), collaborating on projects integrating genomics, epidemiology, and evolutionary biology.

Giel van Doorenمشاهده پروفایل

دانشیار

• Cell Biology
• Parasitology
• Molecular Biology
• +۳ مورد دیگر

Giel van Dooren is an Associate Professor at the Research School of Biology , Australian National University. His research focuses on the cell biology and metabolism of apicomplexan parasites , particularly Toxoplasma gondii and Plasmodium falciparum , aiming to develop novel therapeutic strategies against these pathogens. Education: Bachelor of Arts/Bachelor of Science (University of Melbourne, 2000), PhD (University of Melbourne, 2005) His work explores three core areas: Nutrient acquisition (plasma membrane transporters), Mitochondrial biology (electron transport chain inhibitors, apicoplast-mitochondrion metabolic integration), and Toxoplasma life cycle (felid host genetics). Collaborations include Kiaran Kirk , Adele Lehane , Alex Maier , and Kevin Saliba . Recent publications highlight advancements in understanding mitochondrial transporter functions , divergent respiratory complexes , and nutrient pathway drug targets . His lab actively seeks innovative tools for combating parasitic diseases through molecular physiology and metabolomics. Scientific Awards: College of Science Dean’s Commendation for Excellence in Education - Teaching Excellence (2024) College of Science Dean’s Commendation for Excellence in Education - Outstanding Contribution to Student Learning (2023) Bancroft-Mackerras Medal of the Australian Society for Parasitology (2021) College of Science Dean’s Commendation for Excellence in Education (2020, 2020) Grants & Projects: Na+-dysregulating antimalarials: PfATP4 physiology (2024-2027) Metal transporters in Toxoplasma gondii (2023-2026) Amino acid acquisition in Apicomplexans (2023-2025) Targeting mitochondrial ETC in parasites (2020-2023) Regulating nutrient uptake in intracellular parasites (2020-2022)

• Bioorganic Chemistry
• Chemical Biology
• Organic Chemistry
• +۵ مورد دیگر

Prof. Dr. Norbert Sewald, Chair of Organic and Bioorganic Chemistry at Bielefeld University, is a leading figure in Bioorganic Chemistry , Chemical Biology , and Enzymatic Halogenation . As head of the Organic and Bioorganic Chemistry Group at the Center for Biotechnology (CeBiTec), he drives research on natural products and drug conjugates. Full Professor, Bielefeld University (since 1999) Founding Coordinator, International Graduate School of Chemistry and Biochemistry (2001-2003) Chairman, Institute of Biochemistry and Bioengineering at CeBiTec (2006-2008) Dean, Department of Chemistry (2008-2011) Chairman, Max-Bergmann-Kreis e.V. (since 2010) Coordinator, Marie Skłodowska-Curie Training Networks (MAGICBULLET, 2015-2018; Magicbullet::reloaded, 2020-2023) His research focuses on halogenases for mild peptide bromination, cryptophycin-based tumor targeting , and bioactive natural products from African flora. Collaborative projects span antiplasmodial agents , antibacterial compounds , and neurodegenerative disease inhibitors . Recent work highlights include: Enzymatic halogenation cascades Click-to-release drug conjugates Fluorescent probes for amyloid detection Key affiliations: Faculty of Chemistry Center for Biotechnology (CeBiTec) European Peptide Society (Scientific Affairs Officer, 2016-) Leibniz Institute of Plant Biochemistry (Scientific Advisory Board, 2010-2017)

Scott Lovellمشاهده پروفایل

مدرس ارشد

• Chemical Biology
• Drug Discovery
• Chemical Proteomics
• +۵ مورد دیگر

Dr. Scott Lovell is a Senior Lecturer in Chemical Biology at the University of Bath's Department of Life Sciences. He leads the Lovell Group researching covalent drug discovery at the chemistry-biology-medicine interface, focusing on cancer and antibiotic-resistant infections. His team specializes in peptide synthesis, chemical proteomics, and phage display technologies. Dr. Lovell's research interests include: Covalent phage display for undruggable proteins Targeted covalent macrocycles (TCMs) Protease-activated imaging agents Covalent fragment libraries for cancer treatment His recent publications demonstrate a focus on developing covalent inhibitors through innovative screening platforms, with applications spanning transcription factor inhibition, antimicrobial strategies, and peptide-based drug discovery. Research strongly emphasizes translational approaches combining synthetic chemistry with molecular biology. Dr. Lovell is currently PI on multiple funded projects including: Tackling the Undruggable Cancer Proteome with Covalent Macrocycles (EPSRC) Synthesis of Targeted Covalent Macrocycle Libraries (Royal Society) A Phage Display Approach for Undruggable Proteins (Academy of Medical Sciences) He welcomes doctoral students to his interdisciplinary research team investigating novel chemical modalities for disease treatment.

Frederick R Haseltonمشاهده پروفایل

استاد

• Global Health Technologies
• Molecular Diagnostics
• Nano Science and Technology
• +۳ مورد دیگر

Frederick R. Haselton is a Professor of Biomedical Engineering, Chemistry, and Ophthalmology and Visual Sciences at Vanderbilt University’s School of Engineering. His research focuses on developing low-cost, accessible diagnostic technologies for global health challenges, particularly in resource-constrained settings. He leads the Haselton Lab, a multidisciplinary team advancing innovations like Adaptive PCR, coffee ring-based diagnostics, and quantum dot imaging systems. Education : Ph.D. in Bioengineering from the University of Pennsylvania; B.A. in Mathematics from Haverford College. Research Interests : Dr. Haselton’s work spans molecular diagnostics, nanotechnology, and global health. Key projects include: Adaptive PCR: A revolutionary PCR method using synthetic L-DNA for temperature-independent cycling, enabling point-of-care diagnostics. Coffee Ring Diagnostics: Leveraging evaporation phenomena to create simple malaria and tuberculosis tests requiring no electricity. Quantum Dot Imaging: Developing multispectral tools for retinal and cardiovascular disease monitoring. Global Health Collaborations: Leading LIGHT (Laboratories for Innovation in Global Health Technologies), a cross-disciplinary initiative addressing diagnostic needs in low-resource environments. Grants & Funding : Haselton has secured major grants from NIH, Bill & Melinda Gates Foundation, and others for projects like tuberculosis detection via magnetic bead systems and mobile-connected diagnostic tests. Labs & Teams : The Haselton Lab collaborates with faculty across engineering, medicine, and chemistry. Current personnel include postdocs, graduate students, and undergraduates working on projects ranging from HIV viral load monitoring to SARS-CoV-2 diagnostics.

Shannon Takala Harrisonمشاهده پروفایل

استاد

• Malaria Genomics
• Molecular Epidemiology
• Antimalarial Drug Resistance
• +۲ مورد دیگر

Dr. Shannon Takala Harrison is Professor of Medicine and Epidemiology & Public Health at the University of Maryland School of Medicine, where she serves as Associate Director for CARTI Training Tracks and heads the Genomic Epidemiology Unit within the Malaria Research Program. Her research deciphers molecular mechanisms of malaria parasite evolution and transmission. Education: Ph.D. in Molecular Epidemiology, University of Maryland School of Medicine (2006) B.S. in Zoology, Brigham Young University (1999) Her NIH-supported program investigates genetic determinants of antimalarial drug resistance, parasite population genomics, and molecular epidemiology of malaria. Seminal work identified artemisinin resistance mutations in Southeast Asia and established frameworks for tracking resistance spread. Current projects analyze parasite migration patterns and identify novel resistance markers to partner drugs. Recent publications characterize genomic diversity in Plasmodium populations and identify transporter mutations affecting piperaquine sensitivity. Her research combines field studies in malaria-endemic regions with advanced genomic analyses to inform elimination strategies. Awards and Honors: Outstanding Graduate Mentor Award (2014) Director of Central Intelligence's Exceptional Intelligence Analyst Program (1992, 2004) ACM Recognition of Service Award (2003) UNO Faculty Service Learning Award (2011) She leads population genomic studies across Southeast Asia and Africa through collaborations with the Institute for Genome Sciences. As Track Leader for the Molecular Epidemiology graduate program, she mentors doctoral students investigating genetic epidemiology approaches to global health challenges.