جست‌وجوی استاد و پژوهشگر

Robert Williamsمشاهده پروفایل

دانشیار

• Neuroscience
• Alzheimer's Disease
• Neurodegeneration
• +۱۲ مورد دیگر

Robert Williams is a Reader in the Department of Life Sciences at the University of Bath, actively engaged in research on neurodegenerative diseases, particularly Alzheimer's Disease. His work focuses on synaptic dysfunction, cell signaling abnormalities, and the therapeutic potential of dietary polyphenols such as flavonoids. He leads several funded research projects and mentors doctoral students. University: University of Bath Department: Department of Life Sciences Academic Rank: Reader (equivalent to Associate Professor) Education: Doctor of Science, University of Leeds (1990) Bachelor of Science, University of Leeds (1986) Research Interests: Dr. Williams' laboratory investigates the molecular basis of synaptic and neuronal loss in Alzheimer's and related dementias. His team explores early disease mechanisms, including tau and amyloid-β toxicity, microglial responses, and the neuroprotective effects of plant polyphenols. A key innovation is the use of human stem cell models and microelectrode arrays to study neural network dysfunction, aligning with the 3Rs (Replacement, Reduction, Refinement) principles under NC3Rs. Recent Research Trends: His recent publications (2022–2024) show a strong focus on Alzheimer's disease mechanisms, including tau pathology, microglial modulation by flavonoids like EGCG, and protein aggregation in neurodegeneration. The work integrates molecular neuroscience, immunology, and nutritional biochemistry, often using advanced cellular models and omics approaches. Scientific Service and Recognition: Member, European Science Foundation College of Experts (2022–) Member, Alzheimer's Research UK Grant Review Board (2013–2019) Member, MJFF Review Board (2013) Editorial Board, Neurochemistry International (2015–) Editorial Board, Nutrition and Aging (2012–) Former Editorial Board, Journal of Neurochemistry (1998–2010) Editorial Advisory Board, Journal of Alzheimer's Disease (2018–2019) Advising and Grants: Dr. Williams is accepting doctoral students and has supervised multiple research projects. He is Principal Investigator (PI) on grants from NC3Rs and Alzheimer's Research UK, including projects on MEA technology for neural network studies and microglia-targeted Alzheimer’s interventions. He also serves as Co-Investigator on multidisciplinary projects, such as the Functional Roles of Presynaptic Opioid Receptors and the Multi-User High-Content Confocal Microscope initiative. Labs and Research Teams: His lab is part of the University of Bath Healthy Living Longer Network and collaborates extensively within the UK and internationally. The team employs human stem cell models, microelectrode arrays, and molecular techniques to study neurodegeneration, emphasizing translational and ethical research practices.

• Empathy
• Neuroscience
• Facial Expressions
• +۷ مورد دیگر

Augusta Gaspar is an Associate Professor at the Faculty of Human Sciences of the Portuguese Catholic University , with a PhD in Facial Behavior from NOVA University Lisbon . Her research spans evolutionary psychology, neuroscience, and empathy, focusing on facial expressions, prosocial behavior, and nonverbal communication. Education: PhD, Facial Behavior in Pan and Homo (2001), NOVA University Lisbon Her work contributes to the UN Sustainable Development Goals (SDGs), particularly in education and social well-being. Key projects include: ENGAGED (2025–2027): Political engagement in European youth NHNAI (2022–2025): Intersections of neurosciences and AI Colour and Emotion - Phase 2 (2021–2025): Color-emotion associations Her research interests include empathy development across lifespan, virtual reality interventions for mental health, and ethical dilemmas in animal research. She has presented at conferences like the Swiss Psychological Society (2022) and contributed to edited books on human symbolic evolution. She is a member of the National Forum of Psychology (Order of Portuguese Psychologists, 2020–present) and collaborates internationally on topics like environmental psychology and AI ethics. Her scientific production includes 63 publications, with an h-index of 193 (Scopus).

Denis Jabaudonمشاهده پروفایل

استاد

• Developmental Neurobiology
• Neuronal Circuit Assembly
• Gene Expression in Neurons
• +۷ مورد دیگر

Denis Jabaudon is a Professor and Group Leader in the Department of Basic Neurosciences at the Faculty of Medicine, University of Geneva, where he leads a research laboratory at Campus Biotech. His work focuses on the genetic and molecular mechanisms governing cortical neuron circuit assembly during development. His research interests include developmental neurobiology, neuronal circuit formation, gene expression dynamics in neural progenitors and postmitotic neurons, thalamocortical connectivity, and neural plasticity. He investigates how intrinsic genetic programs and sensory experience interact to determine neuronal identity and circuit function. His lab employs techniques such as in vivo electroporation, transgenic mouse models, single-cell RNA sequencing, and electrophysiology. The most recent publications highlight a strong trend in understanding the temporal patterning of neural progenitors and how this influences the sequential generation of diverse neuronal subtypes. His work demonstrates that molecular birthmarks in progenitors are transmitted to daughter neurons, which then undergo activity-dependent refinement. This research bridges developmental biology, epigenetics, and systems neuroscience, with implications for brain repair and reprogramming. Scientific Awards and Funding: Swiss National Science Foundation Grant (PP00P3-123447) Velux Foundation Funding 3R Foundation Funding Brain and Behavior Research Foundation Funding Joint Leenaards Foundation for Scientific Research Award Denis Jabaudon actively mentors a team of early-career researchers. His lab includes scientific collaborators such as Riccardo Bocchi and Sabine Fièvre, postdoctoral researchers like Awais Javed and Sergi Roig Puiggros, and graduate students including Eline Balavoine, Natalia Baumann, and Moein Sarhadi. His research has been supported by multiple competitive grants, indicating sustained funding and scientific impact. The lab’s work contributes significantly to understanding the fundamental principles of brain development and plasticity. Laboratory and Team: The Jabaudon lab is based at Campus Biotech in Geneva and comprises a multidisciplinary team of scientific collaborators, postdoctoral fellows, graduate students, and technical staff, working collaboratively on projects related to neocortical development and circuit assembly.

Jordi Lopez-Tremoledaمشاهده پروفایل

مدرس ارشد

• Trauma Sciences
• Animal Welfare and Ethics
• Preclinical Imaging
• +۴ مورد دیگر

Jordi Lopez-Tremoleda serves as University Veterinarian and Senior Lecturer in Trauma, Animal Science and Welfare at Queen Mary University of London's Blizard Institute within Barts and The London School of Medicine and Dentistry. He directs the Centre for Trauma Sciences, providing veterinary oversight for research animals and promoting 3Rs principles (Replacement, Reduction, Refinement) in experimental design and regulatory compliance. His educational qualifications include: Doctor of Veterinary Medicine (DVM) PhD Master of Science in Bioethics Lopez-Tremoleda's research develops translational models of trauma, haemorrhage, shock, coagulopathy, and central nervous injury, integrating advanced preclinical imaging to identify biomarkers and enhance clinical applicability. His work bridges veterinary science, trauma medicine, and ethical animal research practices. As a Fellow of the Higher Education Academy (FHEA), he teaches across BSc, iBSc, MSc, and PBL programs in medical education. He serves as Editor-in-Chief of Laboratory Animals and holds council positions in the Laboratory Animals Veterinary Association (LAVA) and Laboratory Animal Science Association (LASA), demonstrating leadership in animal welfare standards. Lopez-Tremoleda actively contributes to Queen Mary's Animal Welfare and Ethical Review Body, ensuring rigorous ethical oversight of animal research while advancing veterinary care protocols and staff training in regulatory compliance.

Robin S. B. Williamsمشاهده پروفایل

استاد

• Molecular Cell Biology
• Neuroscience
• Pharmacology
• +۸ مورد دیگر

Professor Robin S. B. Williams is a Professor of Molecular Cell Biology at Royal Holloway University of London, where he has been based since 2006. He serves as the Head of the Centre for Biomedical Sciences and conducts research in molecular cell biology, neuroscience, pharmacology, and drug development. His work primarily utilizes the social amoeba Dictyostelium discoideum as a model system, contributing to animal replacement, reduction, and refinement (3Rs) research approaches. Williams earned his PhD in molecular cell biology from the University of Melbourne (Australia) in 1994, followed by postdoctoral positions at St Andrews University and University College London (UCL), and an independent Wellcome Trust Career Development fellowship at UCL. His research focuses on understanding cellular mechanisms underlying neurological disorders and developing new therapeutic treatments. Key areas include: Developing better treatments for epilepsy, particularly through studying how medications like valproic acid work at cellular levels Investigating the evolutionary origins of proteins involved in diseases like Alzheimer's Exploring cellular mechanisms underlying bipolar disorder and its treatment Analyzing natural products and their potential medical applications Studying molecular mechanisms of bitter taste perception Analysis of Williams' recent publications reveals a strong focus on epilepsy treatment mechanisms, particularly related to ketogenic diets and medium-chain fatty acids. His work increasingly integrates findings from Dictyostelium research with mammalian models to identify novel therapeutic targets. There's also significant emphasis on understanding how natural compounds like cannabinoids, flavonoids, and curcumin function in health and disease. Williams has received notable recognition including: Medical Advisory Board member (2023 ongoing), Matthew Friends Charity UK Global Executive Board member, International Neurological Ketogenic Society (2017 ongoing) Program Committee Chair for Global Symposium on Medical Ketogenic Dietary Therapies (2021-2023) Microbiology Society UK (Eukaryotic division) committee member (2017-2020) Multiple FACULTY 1000 Selected publications Williams has supervised numerous PhD students and postdoctoral fellows, including current researchers Kateryna Maslova and George Mears. His research has been supported by significant grants including funding from the Medical Research Council and Biotechnology and Biological Sciences Research Council. Notably, he leads a project "Replacing valproate with a safer, broad-spectrum drug for epilepsy treatment" (2024-2026). His laboratory focuses on the Centre for Biomedical Sciences at Royal Holloway, where they utilize Dictyostelium discoideum as a model system to investigate neurological disorders, drug mechanisms, and natural product effects. The lab has established collaborations with institutions worldwide and industry partners including Vitaflo Ltd and GlaxoSmithKline.

• Public Administration
• Sustainability
• Policy Analysis
• +۷ مورد دیگر

Dr. Marie-Jeanne Schiffelers is an Associate Professor and Senior Consultant at Utrecht University's Faculty of Law, Economics and Governance , affiliated with the Department of Public Administration and Organizational Science . She leads the USBO Consultancy unit, focusing on policy innovation, sustainability, and regulatory frameworks. Education: PhD in Veterinary Science (2016), Master in Global Sustainability Sciences (1995) Core Research Areas: Policy Analysis , 3R Models (alternatives to animal testing), and Professional Performance Key Projects: Evaluation of anti-radicalization programs, regulatory acceptance of non-animal toxicology methods, and organizational assessments for police and healthcare sectors Her publications since 2012 emphasize collaborative governance , regulatory innovation , and sustainability policy , with frequent co-authorship in interdisciplinary journals. Recent work includes organizational learning in public sectors and ethical implications of emergency legislation. She serves as vice-chair of the Biodiversity Council at Utrecht University and contributes to executive education programs. Her consultancy spans government agencies, healthcare institutions, and legal bodies, focusing on stakeholder-driven reforms and administrative efficiency.

Diane Leeمشاهده پروفایل

پژوهشگر ارشد

• Epithelial Cell Biology
• Equine Asthma
• Bovine Tuberculosis (BTB)
• +۳ مورد دیگر

Diane Lee is a Research Fellow B in Pathology and Infectious Diseases at the University of Surrey's School of Veterinary Medicine. She holds a PhD, MSc, and BSc (Hons) and specializes in ex vivo/in vitro cell biology with a focus on drug discovery and pre-clinical research. Her roles include managing the Impact Acceleration Account and KE (MRC & PhD/ECR) and serving on the NASPA Sub-committee. Education: PhD in Pharmacy and Biomolecular Sciences from the University of Brighton (2015), MSc and BSc from unspecified institutions. Research Interests : Equine Asthma: Developing nasal brush models to study mechanisms of asthma and Notch signaling in goblet cell hyperplasia. Bovine Tuberculosis (BTB): Created a bovine alveolus model using co-culture of alveolar and endothelial cells to study host-pathogen interactions, reducing animal use. 3Rs Principles: Championing replacement/refinement/reduction of animal experiments through in vitro models. Publications : Over 15 peer-reviewed articles, including work on bovine lung-on-chip models, equine asthma nasal models, and HSP70 inhibitors. Collaborations : Works with NIBSC, Pirbright Institute, and APHA. Active in developing organ-on-chip technologies and validating cell culture models for respiratory diseases. Labs/Teams : Leads projects on equine respiratory models and bovine tuberculosis at the University of Surrey, with a focus on translational veterinary medicine.

• Economics
• Circular Economy
• Sustainability
• +۵ مورد دیگر

Lopez Luciano serves as an Assistant Professor at EHL Hospitality Business School, part of the University of Applied Sciences and Arts Western Switzerland (HES-SO) in Lausanne, Switzerland. His primary academic focus spans economics with specialized expertise in circular economy, sustainability, and hospitality management. He teaches core courses in Microeconomics and Macroeconomics to hospitality business students. Dr. Lopez holds a BSc HES-SO in Hospitality and Hospitality Professions from EHL Hospitality Business School. His educational background provides him with both theoretical and practical knowledge in the hospitality sector, which informs his research approach. His research interests center on the intersection of economic principles and sustainable business practices within the hospitality industry. Lopez investigates how circular economy principles can be effectively implemented in hotels beyond basic '3Rs' (Reduce, Reuse, Recycle) practices. His work demonstrates that guests respond more positively to 'Rethink' and 'Redesign' approaches that fundamentally transform hotel processes and infrastructure. Additionally, he has made significant contributions to development economics, particularly examining the relationship between official development assistance (ODA) and tourism demand, as well as the economic returns on bilateral aid for donor countries like Switzerland. His econometric expertise is evident in his work on Granger causality in panel datasets and its application to economic growth and environmental impact analysis. Lopez's publication record shows consistent scholarly output with a focus on high-impact topics in hospitality economics. His recent work demonstrates a clear trajectory connecting economic theory with practical applications in sustainability and international development. The integration of econometric methods with hospitality management issues represents a distinctive feature of his research approach. Regarding academic mentorship, while specific students are not listed in available documentation, Lopez appears to be actively engaged in guiding research within his areas of expertise. His work with colleagues like Florent Girardin on circular economy in hospitality suggests collaborative supervision of research projects. Though specific grant information isn't provided, his research on Swiss ODA and tourism demand likely involved funded projects given the extensive data collection requirements. While no specific laboratories or research centers are explicitly mentioned, Lopez appears to be part of research teams focused on sustainable hospitality practices and economic development. His collaborations with researchers across different institutions suggest participation in broader research networks examining the economic dimensions of sustainability in the hospitality sector.

• Cell Biology
• Toxicology
• Tissue Engineering
• +۳ مورد دیگر

Dr. Carine Gaiser is a Researcher at the School of Life Sciences, FHNW University of Applied Sciences and Arts Northwestern Switzerland. She is affiliated with the Institute for Chemistry and Bioanalytics, focusing on cell biology and in vitro toxicology. Her research employs cell cultures and tissue engineering to investigate disease mechanisms and substance efficacy/toxicity. Key collaborations include work on blood-brain barrier models, neuroregenerative scaffolds, and liver toxicity pathways. Her research interests span regenerative medicine, drug toxicity assessment, and biomarker discovery for fibrosis. She contributes to 'New Approach Methodology' (NAM) initiatives promoting non-animal testing strategies. Dr. Gaiser has published on topics ranging from miRNA roles in liver fibrosis to 3D cell culture platforms for high-throughput screening. Her work emphasizes translational applications, including in vitro models for drug development and tissue engineering innovations. She has presented findings at conferences like the ASHP Midyear Meeting and collaborates with interdisciplinary teams to advance alternative toxicology methods.

• Immunology
• Tuberculosis Research
• Vaccine Development
• +۴ مورد دیگر

Rachel Tanner is an Associate Professor at the University of Oxford, holding dual appointments as a Research Fellow at Wolfson College and a Lecturer in Human Sciences at Wadham College. She also serves as the Access and Outreach Officer for the Institute of Human Sciences, driving initiatives to broaden participation in higher education. Her academic foundation includes an MA in Biological Sciences and DPhil in Clinical Medicine, both earned at the University of Oxford. These qualifications underpin her expertise in clinical immunology and vaccine research. Dr. Tanner's research program centers on tuberculosis vaccine development, with a dual focus on identifying immune correlates of protection and characterizing humoral responses to BCG vaccination. She pioneers in vitro functional assays like the mycobacterial growth inhibition assay (MGIA) to evaluate vaccine efficacy while rigorously applying 3Rs principles (replacement, reduction, refinement) to minimize animal use. Her work extends to controlled human infection models for TB, investigations into non-specific effects of BCG vaccination, and bovine TB vaccine development, addressing critical gaps in global tuberculosis control strategies. Her scientific leadership is recognized through prestigious awards including the TB Vaccine Initiative (TBVI) Young Scientist Award (2017), Collaboration for TB Vaccine Discovery (CTVD) Early Career Scientist Award (2018), and Women of the Future Award for Science (2019). Dr. Tanner secures competitive funding from UKRI-GCRF network VALIDATE, NC3Rs, UFAW, and RSTMH. She leads high-impact projects including the non-human primate MGIA initiative and assay harmonization efforts within the European Research Infrastructures for Poverty Related Diseases (EURIPRED). Her mentorship extends to training researchers in advanced immunological techniques and ethical research practices. She actively shapes her field through service on the Scientific Reports Editorial Board, the British Society for Immunology Vaccine Affinity Group, the Acid Fast Club, and Oxford University's Animal Care and Ethical Review 3Rs subcommittee. Her collaborative networks span international consortia focused on poverty-related diseases and tuberculosis elimination.

Nicolas Védrenneمشاهده پروفایل

دانشیار

• Toxicology
• Environmental Health
• Personalized Medicine
• +۵ مورد دیگر

Nicolas Védrenne serves as an Associate Professor in Toxicology and Environmental Health at the Faculty of Pharmacy, University of Limoges, and is affiliated with Inserm UMR 1248 (Pharmacology and Transplantation). His research office is located in the CBRS building (2nd floor, university side, office 235) at the Limoges campus. His educational background includes: PhD in Neuroscience (2013), University of Limoges, focusing on astrocyte populations in CNS injury repair Master’s in Cellular/Molecular Biology & Genetics (2010), University of Poitiers, specializing in stem cells Bachelor’s in Cellular Biology & Genetics (2008), University of Poitiers University Diploma in Animal Experimentation Level 1 (2012), University of Paris Descartes Dr. Védrenne pioneers microphysiological systems research, developing innovative Organ-on-a-Chip platforms to model human organ functions and drug interactions. His work integrates microfluidics to simulate physiological flows (blood/urine), advancing personalized medicine through pharmacokinetic modeling while adhering to the 3Rs principle (Replacement, Reduction, Refinement) for animal testing alternatives. Key innovations include proximal tubule-on-a-chip systems for studying drug membrane transporters and xenobiotic toxicity. His research drives interdisciplinary collaborations across microfabrication, biomaterials, and cell biology to create human-relevant models that overcome limitations of animal studies. Current work focuses on multi-organ signaling (liver-kidney interactions) using microphysiological systems, with applications in drug toxicity screening and therapeutic development. As an educator, he teaches toxicology across pharmacy programs (Years 3-5), Health Sciences, and Pharmacy Technician preparation courses, covering toxicovigilance, regulatory toxicology, addictionology, and environmental health. His laboratory work within the CBRS facility emphasizes translational research bridging fundamental toxicology with clinical applications.

Nicole Schuppمشاهده پروفایل

دانشیار

• Toxicology
• Nephrology
• Kidney Disease
• +۴ مورد دیگر

Nicole Schupp serves as Associate Professor at the Institute of Toxicology, Heinrich Heine University of Düsseldorf, where she leads the Workgroup Kidney Damage and Nephroprotection. Her research addresses critical gaps in understanding toxin-induced kidney injury mechanisms and developing protective interventions for chronic kidney diseases. Her primary research focuses on nephrotoxicology, specifically investigating how genotoxic/non-genotoxic substances cause acute and chronic kidney damage through oxidative stress and DNA injury. Key areas include uremic toxin-mediated DNA damage, Nrf2 transcription factor regulation in renal protection, and regeneration mechanisms in proximal tubules. She pioneers 3R-compliant toxicity testing using precision-cut kidney slices and induced pluripotent stem cell-derived kidney models to reduce animal experimentation. Analysis of her 2020-2023 publications reveals strong thematic continuity in aldosterone-induced renal damage pathways, oxidative stress biomarkers, and Nrf2 signaling dysregulation. Her work consistently bridges molecular mechanisms (DNA damage, oxidative stress) with clinical applications (biomarker development, nephroprotective agents), particularly in hypertension-related kidney pathology. Dr. Schupp actively mentors two doctoral students (Isaac Musong Mboni Johnston and Sören Hartmann) within Research Training Group 2578 (RTG 2578), which focuses on stem cell models for kidney damage research. Her group collaborates with technical staff including Kerstin de Mezzo to maintain advanced experimental platforms. The Workgroup Kidney Damage and Nephroprotection operates state-of-the-art facilities for precision-cut kidney slice culture, stem cell differentiation, and in vivo modeling, enabling comprehensive investigation of nephrotoxic mechanisms and protective strategies against environmental and metabolic toxins.

Margot Michelمشاهده پروفایل

استاد

• Family Law
• Family Procedural Law
• Medical Law
• +۷ مورد دیگر

Prof. Dr. iur. Margot Michel is a Professor at the University of Zurich's Faculty of Law, where she holds the Chair of Private Law, Comparative Law, Animal Welfare Law and Legal Philosophy. She is actively engaged in research and teaching across multiple legal domains including family law, medical law, and animal law. Her research interests span Family Law and Family Procedural Law, Medical Law, Personal Law, Disability Law, and particularly Animal Law where she has made significant contributions. Michel is pioneering work in the legal recognition of animals, exploring how legal frameworks can move beyond treating animals as mere property. Her habilitation thesis "Legal Community with Animals. A Search for Clues" (2024) represents a major contribution to this field. Michel's publication record shows a clear evolution from traditional family and medical law toward increasingly innovative work at the intersection of law and animal studies. Her recent publications demonstrate a sophisticated integration of legal theory, practical application, and ethical considerations, particularly in how legal systems can better accommodate non-human entities. She has been instrumental in establishing animal law as a legitimate academic discipline in Switzerland. She serves as co-editor of the Journal of Animal Law, Ethics and One Health (LEOH) since 2023 and is a member of the editorial board of FamPra.ch - Praxis des Familienrechts since 2022. Michel has organized and participated in numerous conferences including the "Animals in Switzerland, Japan and Beyond" symposium at the University of Zurich in March 2024. Co-editor, Journal of Animal Law, Ethics and One Health (LEOH) since 2023 Member of editorial board, FamPra.ch - Praxis des Familienrechts since 2022 Co-founder and leader, Center for Animal Law and Ethics (CALE) Participant in NRP 79 – Animals, Research and Society Michel leads the Center for Animal Law and Ethics (CALE) at the University of Zurich, which serves as a hub for interdisciplinary research connecting legal scholars with veterinarians, philosophers, and scientists. Through CALE, she has organized numerous workshops on the 3Rs principle (Replacement, Reduction, Refinement) in animal research and has been instrumental in developing university policies to accelerate animal replacement in research settings.

Guillermo Adolfo Repetto Kuhnمشاهده پروفایل

استاد

• Toxicology
• Forensic Sciences
• Criminalistics
• +۳ مورد دیگر

Guillermo Adolfo Repetto Kuhn is a Professor at Pablo de Olavide University in Seville, Spain, where he works in the Department of Molecular Biology and Biochemical Engineering within the Health Science and Techniques domain. His primary research area is Toxicology, with specific focus on Forensic Sciences and Toxicology through the FORYTOXICOL Research Group. Dr. Repetto Kuhn holds significant leadership positions in the toxicology community: President of REMA (Spanish Network of Alternative Methods) Moderator of TOXICOL - Toxicology Forum Moderator of 3ERRES - Forum on Alternative Methods to Animal Experimentation Member of AETOX (Spanish Toxicology Society) Member of GTEMA (Group on Alternative Methods) His research spans multiple domains of toxicology, with particular emphasis on developing and promoting alternative testing methods to animal experimentation. Dr. Repetto Kuhn has created important resources like the Inventory of Spanish Institutions and Scientists Interested in Alternative Methods and co-authored "FUNDAMENTAL TOXICOLOGY, 4th Ed" (2009) with Manuel Repetto Jiménez. His work bridges forensic toxicology, environmental toxicology, and regulatory science, with significant contributions to understanding chemical risks and developing safer testing methodologies. Analysis of Dr. Repetto Kuhn's publication record reveals a strong focus on environmental toxicology (particularly regarding endocrine disruptors like BPA), alternative testing methods using biological models, and applications of toxicology to medical genetics and pharmacology. His work demonstrates consistent commitment to advancing toxicological science while promoting ethical research practices that reduce reliance on animal testing. Dr. Repetto Kuhn actively contributes to academic programs including the International Master in Toxicology (Academic Committee), Master's Degree in Criminology and Forensic Sciences, Bachelor's Degree in Criminology, and doctoral programs in Biotechnology, Biomedicine and Health Sciences at Pablo de Olavide University.

• Cancer Biology
• Preclinical Cancer Pharmacology
• Drug Resistance in Colorectal Cancer
• +۵ مورد دیگر

Dr. Steven Shnyder is a Senior Lecturer in Cancer Biology at the University of Bradford's School of Pharmacy & Medical Sciences within the Faculty of Life Sciences. With over 35 years of experience as a research scientist, including 30 years post-doctoral work and 24 years specifically in preclinical cancer pharmacology at Bradford, he has established himself as a leading expert in cancer drug development and testing. His research interests span several critical areas in oncology, with a particular focus on identifying mechanisms of drug resistance in colorectal cancer. Dr. Shnyder has developed expertise in characterizing reticuloplasmins as anticancer drug targets, pharmacology of vascular disrupting agents, development of 3Rs methodologies, exploitation of fluorescent properties of anti-cancer therapeutics, and evaluation of the drugability of the tumour cell glycocalyx. His work bridges the gap between basic science and clinical application, with several compounds his team has screened progressing to clinical trials. Analysis of Dr. Shnyder's publication record reveals a consistent focus on improving preclinical cancer models, understanding drug resistance mechanisms, and implementing ethical research practices through the 3Rs principle. His most recent work shows increasing emphasis on translational research approaches that connect laboratory findings with potential clinical applications, particularly in colorectal cancer treatment. 80+ peer-reviewed journal articles 4 book chapters on in vivo methodology Multiple conference publications Dr. Shnyder serves as a Home Office Project and Personal Licence holder, managing both in vivo and in vitro studies at the Institute of Cancer Therapeutics (ICT). He line-manages a Research Associate focused on in vivo studies and a Research Technician specializing in in vitro screening. His leadership extends to co-investigating project grants and studentships focused on improving preclinical cancer pharmacology methodology from a 3Rs standpoint. His research team includes Patricia Cooper (Experimental Officer), Gary Lawson (Research Technician), and Marcella Sini (YCR Programme Grant Postdoctoral Researcher), working collaboratively with colleagues including L Patterson, P Loadman, R Falconer, and K Pors.