معرفی
Zhongyuan Zuo is a Senior Staff Scientist at the Yale School of Medicine, affiliated with the Department of Cell Biology and the Center for Cellular and Molecular Imaging. He holds an MS in Molecular and Cellular Biology (2014) and a BS in Molecular Biology (2012) from the University of Denver. His research focuses on molecular mechanisms underlying neurodegenerative diseases, mitochondrial biology, and lysosomal dysfunction, utilizing Drosophila models and CRISPR-based tools. Collaborations include frequent work with Berrak Ugur, PhD, and other Yale investigators.
Key research areas include mitochondrial dynamics, neuroinflammation, and the effects of environmental toxins like spinosad and neonicotinoid insecticides. His lab contributes to developing therapeutic strategies for disorders like infantile neuronal axonal dystrophy (INAD/PARK14) and advancing CRISPR gene-editing techniques. Zuo’s work bridges cell biology, genetics, and neurology, addressing fundamental questions in cellular homeostasis and disease pathogenesis.
Publications span high-impact journals such as Nature Communications, Cell Metabolism, and Science Advances, highlighting his contributions to understanding Wnt signaling, lipid metabolism, and mitochondrial dysfunction. His lab is part of the Electron Microscopy Facility at Yale CCMI, leveraging advanced imaging techniques for cellular and molecular studies.
