Zhongyuan Chen

Zhongyuan Chen, PhD, is an Assistant Professor in the Division of Biostatistics at the Medical College of Wisconsin (MCW). She holds a PhD in Statistics from Rice University and previously served as a Visiting Assistant Professor at Purdue University's Department of Statistics. Her research focuses on integrating statistical methodologies with biosciences, cancer genomics, and computational biology, emphasizing applications in personalized medicine, high-dimensional data analysis, and large-scale scientific computing. Dr. Chen collaborates extensively with cancer researchers at institutions like MCW Cancer Center, MD Anderson Cancer Center, and the IU School of Medicine.

Her key research interests include statistical machine learning for treatment recommendation, causal inference, and cancer genomic data analysis. She has developed novel strategies for analyzing somatic mutations and germline variations, as well as improving eigenvalue solution algorithms for numerical computations. Dr. Chen's work bridges statistical theory with practical biomedical applications, particularly in oncology and precision medicine.

Notable publications highlight her contributions to understanding mitochondrial genomic variants in transplantation outcomes, Hippo-YAP pathway regulation in bone metastasis, and metabolic subtypes in cancers. She actively seeks motivated students and postdocs for collaborative research projects, emphasizing interdisciplinary approaches to biomedical challenges. Teaching responsibilities include courses in biostatistical computing and statistical quality control.