معرفی
Yuval Ebenstein is an Associate Professor in the Department of Chemical Physics at Tel Aviv University's School of Chemistry. He founded and directs the university's Entrepreneurship and Innovation Center (2018–Present). His research integrates optical imaging, nanotechnology, and genomics to develop novel tools for epigenetic analysis and single-molecule diagnostics.
Education
- Ph.D. in Physical Chemistry, Hebrew University (2007)
- M.S. in Physical Chemistry, Hebrew University (2001)
- B.S. in Physics and Chemistry, Hebrew University (2000)
Research Focus
Ebenstein's lab pioneers optical barcoding and nanofluidic systems for genomic/epigenetic mapping. Key areas include: single-molecule genomics using super-resolution imaging, epigenetic biomarker detection for cancer diagnostics, and high-throughput biosensors for clinical applications. The team also develops CRISPR-assisted nanopore sequencing and DNA nanostructure engineering techniques.
His publications emphasize translational epigenetics, with innovations in detecting 5-hydroxymethylcytosine (5hmC) as a cancer biomarker and multiplexed DNA damage profiling. Recent work advances nanochannel-based genome mapping and enzyme-driven DNA functionalization.
Awards & Grants
- Raymond and Beverly Sackler Career Development Chair (2013–2014)
- ERC Consolidator Grant: €2.75M for 'MultiplexGenomics' (2019–2024)
- EU Consortium Grant: €1.1M for 'Genomic Diagnostics Beyond the Sequence' (2015–2019)
- ERC Starter Grant: €1.7M for 'Beads on String Genomics' (2013–2019)
Leadership
Ebenstein leads a dynamic team of 20+ PhD/Master's students and postdocs, focusing on interdisciplinary projects bridging chemistry, physics, and biomedicine. The lab collaborates globally with institutions like UCLA and develops clinically applicable technologies through Tel Aviv University's innovation ecosystem.
