Karolin Frykholm

Karolin Frykholm is a Researcher at Chalmers University of Technology's Chemical Biology division. She works in Professor Fredrik Westerlund's research group, utilizing nanochannels and fluorescence microscopy to study single DNA molecules and DNA-protein interactions. Her work enables DNA sequence mapping, bacterial typing, plasmid identification, and antibiotic resistance gene detection.

• Doctoral Thesis (2009): Aspects of DNA Strand Exchange: Recombination Proteins and Model System Studies
• Licentiate Thesis (2006): Shining polarized light on recombination proteins

Her research spans molecular biology, biophysics, and nanotechnology, with a focus on DNA conformational changes, protein binding dynamics, and antibiotic resistance detection. Publications highlight collaborations with interdisciplinary teams across biomicrofluidics, genomics, and medical genetics.

Key technological applications include optical DNA mapping, Nanofluidic systems, and CRISPR/Cas9 integration for molecular diagnostics. Her work contributes to single-molecule analysis, plasmid characterization, and DNA repair mechanism studies.