معرفی
Yumei Wu, PhD, is a Research Scientist in the Department of Neuroscience at the Yale School of Medicine, Yale University. She holds a PhD from Okayama University (2007). Her research focuses on synaptic vesicle biogenesis, endocytic pathways, and mechanisms underlying neurodegenerative diseases like Parkinson’s. Key contributions include elucidating roles of proteins such as synaptophysin, ATG9A, and VPS13B in synaptic and cellular processes.
Collaborations include work with Pietro De Camilli, Hanieh Falahati, and Berrak Ugur on topics such as spine apparatus formation and Golgi cisternal dynamics. Her studies employ advanced techniques like FIB-SEM 3D imaging and proximity proteomics to explore membrane structures and protein interactions. Recent publications highlight synergistic effects of Parkinsonism-linked mutations on dopaminergic axons and the role of synapsin condensates in vesicle organization.
Research spans cellular mechanisms in neurons, lipid transport, and autophagy, with implications for understanding neurodegenerative disorders.