معرفی
Peng Xu is an Associate Research Scientist in Neuroscience at Yale School of Medicine, part of Yale University. Their research focuses on lipid transport proteins, neurodegenerative diseases, and cellular membrane dynamics. Key collaborations include work with Pietro De Camilli and Shawn Ferguson, investigating proteins like VPS13C/PARK23 and GSAP in Alzheimer’s and Parkinson’s disease contexts. Xu’s studies span ER-lysosome interactions, mitochondrial signaling, and the role of lipid metabolism in neurological disorders.
Publications highlight advancements in understanding VPS13 proteins’ roles in membrane contact sites and STING signaling, as well as GSAP’s impact on γ-secretase activity. Research also explores erythroid differentiation and iPSC-derived dopaminergic neuron models for Parkinsonism studies. Xu’s work bridges molecular biology, cell signaling, and translational neuroscience, with implications for developing therapies targeting neurodegenerative pathways.