Yu Shi

Dr. Yu Shi, M.D., M.P.H., is a Physician Scientist at Mayo Clinic College of Medicine specializing in pediatric anesthesiology and outcomes research. Currently affiliated with the Department of Anesthesiology and Perioperative Medicine and Pediatrics, Dr. Shi leads investigations into anesthesia neurotoxicity, health disparities, and tobacco control.

Research interests center on:

• Pediatric anesthesia safety and neurodevelopmental outcomes (MASK Study)
• Racial/ethnic disparities in surgical care and ADHD diagnosis
• Perioperative tobacco cessation interventions
• Epidemiology of anesthesia complications in children

Recent publications span high-impact journals including Circulation, Science, and JAMA Network Open, with 2025 work focusing on vascular biology mechanisms and AI-driven protein modeling.

Scientific recognition includes:

• Full Tuition Scholarship from Johns Hopkins (2007)
• Board Certification in Anesthesiology and Pediatric Anesthesiology (2016)

Dr. Shi directs multiple institutional committees including the Pediatric Research Committee and AI Advisory Committee, with active grants supporting population-based outcomes research and tobacco control program implementation.