Yonglun Luo

Professor Yonglun Luo is a leading academic at Aarhus University, affiliated with DANDRITE and the Department of Biomedicine. His research focuses on genome editing technologies (e.g., CRISPR), regenerative medicine, and translational applications such as xenotransplantation. Key projects include developing safer pig models for organ transplantation and studying extrachromosomal circular DNA (eccDNA) in cancer progression. He leads a multidisciplinary group applying cutting-edge tools like single-cell RNA/ATAC sequencing and machine learning.

Research interests span biomarker discovery, CRISPR tool optimization, and ethical frameworks for gene therapy. He collaborates internationally on initiatives like the FarmGTEx consortium and the EU COST Action on genome editing. Teaching responsibilities include advanced courses in genome engineering for PhD students and personalized medicine for medical trainees.

Current projects include EXOCURE (CRISPR-based muscle stem cell therapy for Duchenne muscular dystrophy) and CIRCULAR VISION (eccDNA dynamics modeling). His lab's innovations include TRAP-seq for CRISPR off-target analysis and pig cell landscape mapping for xenotransplantation compatibility.