معرفی
Yilin Yang is an Associate Research Scientist in the Iwakiri Lab within the Department of Internal Medicine at the Yale School of Medicine. Her research focuses on liver sinusoidal endothelial cells, lymphatic biology, and alcohol-induced liver disease. She investigates mechanisms underlying liver dysfunction, cirrhosis, and fibrosis, with particular attention to the role of molecular pathways like Hsp90 acetylation and interleukin signaling.
Yang holds a PhD and has contributed to seminal studies on liver lymphatic endothelial cells, including their structural features and therapeutic implications in conditions like primary sclerosing cholangitis (PSC). She received the 2023 Gupta Family Pilot Award for her innovative work exploring liver lymphatic systems in PSC treatment.
Her lab employs advanced techniques such as single-cell transcriptomics, quantitative imaging protocols, and molecular biology to dissect disease mechanisms. Collaborations with experts like Yasuko Iwakiri and Matthew McConnell highlight her interdisciplinary approach to translational hepatology research.
Yang’s work bridges basic science and clinical applications, aiming to identify novel therapeutic targets for liver diseases. Her research spans topics including platelet signaling in cirrhosis, mitochondrial dysfunction in ischemic injury, and the role of succinate in cardiac metabolism, showcasing a broad expertise in biomedical research.
