معرفی
Jain Jeong is an Associate Research Scientist at Yale School of Medicine with primary appointments in the Department of Internal Medicine and Digestive Diseases. They lead significant research efforts within the Iwakiri Lab, focusing on liver pathophysiology with particular emphasis on lymphatic systems and metabolic disorders.
Dr. Jeong earned their PhD from Kyungpook National University in 2018, establishing a strong foundation in biomedical research that has led to significant contributions in hepatology. Their educational background provided the necessary expertise to investigate complex liver diseases using advanced molecular and imaging techniques.
Dr. Jeong's research program centers on liver lymphatic systems and their critical role in various liver pathologies. Their work spans several interconnected areas including liver fibrosis mechanisms, lymphatic vessel architecture, metabolic liver diseases, and neural regulation of hepatic lymphangiogenesis. They have pioneered advanced visualization techniques for studying lymphatic structures and applied single-cell transcriptomics to understand zone-specific alterations in liver sinusoidal endothelial cells. Their research bridges multiple disciplines including hepatology, vascular biology, neuroscience, and metabolic medicine, with particular focus on the brain-liver axis in conditions like hepatic encephalopathy.
Dr. Jeong's publication record demonstrates a clear progression in understanding liver lymphatic systems, with recent work focusing on interleukin-7-based identification of liver lymphatic endothelial cells, sympathetic nervous system regulation of hepatic lymphangiogenesis, and lymphatic dysfunction as a therapeutic target in nonalcoholic steatohepatitis. Their research consistently addresses fundamental questions about liver pathophysiology while maintaining strong translational potential for developing novel therapeutic approaches.
- Early Career Investigator Award in Basic Science from the American Association for the Study of Liver Diseases (AASLD, 2023)
Dr. Jeong collaborates extensively with Dr. Yasuko Iwakiri (lab director), Dr. Matthew McConnell, Dr. Yilin Yang, and Dr. Xuchen Zhang. Their research is supported by grants focused on liver diseases, lymphatic system functions, and metabolic disorders, contributing significantly to Yale's leadership in digestive diseases research. They participate in multidisciplinary research initiatives that bridge basic science and clinical applications through the Yale Liver Center.
As a key member of the Iwakiri Lab, Dr. Jeong contributes to Yale's Digestive Diseases Research Core, working with a multidisciplinary team to advance understanding of liver pathophysiology. Their work is integral to developing novel therapeutic approaches for liver diseases and has positioned Yale as a leader in lymphatic system research related to liver pathology. Current research directions include further exploration of lymphatic system roles in metabolic liver diseases and development of biomarkers for early detection of liver fibrosis progression.