Yanqing Anna Gong

Yanqing Anna Gong is a Researcher in the Department of Medicine at the Perelman School of Medicine, University of Pennsylvania. Her work focuses on vascular-immune interactions in tissue repair and cancer, particularly mechanisms linking endothelial cell plasticity to macrophage polarization and therapeutic resistance.

• M.S. in Medicinal Chemistry, China Pharmaceutical University (2000)
• PhD in Pharmacology, China Pharmaceutical University (2003)

Dr. Gong’s research explores:
Vascular Regulation of Inflammation: How endothelial cells modulate macrophage-driven immune responses in cardiac repair and tumors.
Cardiac Repair Post-Infarction: The role of endothelial plasticity in aberrant vascularization and heart tissue recovery.
Cancer Immunotherapy Resistance: Mechanisms of vascular-mediated immune suppression in glioblastoma and strategies to enhance CAR-T efficacy.

Her recent publications highlight trends in:
• Radiation-induced metabolic reprogramming in cancer
• Vascular control of macrophage immunosuppression
• Targeting endothelial metabolism to overcome tumor resistance
• Ischemia and fracture repair via stromal-immune crosstalk

Dr. Gong’s work bridges vascular biology, immunology, and translational applications, with affiliations at the Smilow Center for Translational Research.