معرفی
Yang Yang, PhD is an Assistant Professor in the Department of Neuroscience and Experimental Therapeutics at Penn State University, with research focused on neural mechanisms of cognition using behavioral, electrophysiological, and pharmacological approaches. His work primarily investigates neurological and neurodegenerative disorders, addiction, and cognitive impairment related to aging.
His educational background includes:
- PhD in Biophysics, Chinese Academy of Sciences (2008)
- BA in Biomedical Engineering, Capital Medical University (2003)
Dr. Yang's research focuses on understanding neural mechanisms of cognition via behavior, electrophysiology, and pharmacology. His primary diseases of interest include neurological and neurodegenerative disorders and addiction. His key disciplines span neuroscience, electrophysiology, behavior and addiction, physiology, pharmacology, drug development and discovery, and translational medicine. A significant portion of his work centers on dopamine receptor function, particularly D1 receptors, and their role in cognitive processes like working memory.
Analysis of Dr. Yang's recent publications reveals a strong emphasis on dopamine D1 receptor agonists and their therapeutic potential for cognitive disorders. His research spans from basic neuroscience investigations of prefrontal cortex physiology to translational applications for age-related cognitive decline and Parkinson's disease. The work demonstrates an interdisciplinary approach combining molecular pharmacology, electrophysiology, and behavioral testing in both rodent and primate models.
Dr. Yang has an h-index of 13 with 1,523 citations, indicating significant scholarly impact in his field. His research has been supported by multiple grants from prestigious organizations including the National Institute on Aging, Brain and Behavior Research Foundation, and American Federation for Aging Research.
Dr. Yang has secured multiple research grants totaling significant funding, with four major projects documented. His current active project (2024-2026) focuses on "Discovery of functionally selective dopamine ligands for age-related cognitive decline" funded by the National Institute on Aging. Previous projects include research on dopamine D1-KCNQ Channel Influences on Dorsolateral Prefrontal Cortical Network Physiology in Primates and Nicotinic Restoration of Prefrontal Cortex Physiology in Aged Monkeys. His research demonstrates a consistent focus on the neural basis of cognitive function and potential therapeutic interventions for cognitive disorders.
While specific lab information isn't detailed in the available text, Dr. Yang's research appears to involve collaborations with experts in computational neuroscience, pharmacology, and aging research, suggesting a multidisciplinary team approach to investigating cognitive neuroscience questions.
