WeiXing Shi

WeiXing Shi is a Professor in both the School of Pharmacy (Pharmaceutical and Administrative Sciences) and the School of Medicine (Physiology Division). His research focuses on the neurobiology and pharmacology of brain disorders including schizophrenia, Parkinson’s disease, ADHD, and drug addiction. He employs techniques such as in vivo/in vitro electrophysiology, optogenetics, and fiber photometry. Key findings include the role of adrenergic α1 receptors in psychostimulant effects on dopamine neurons, and the functional coupling between prefrontal cortex activity and midbrain dopamine neurons. His work also explores cortical Up states induced by amphetamines and their implications for attention and arousal.

His articles span neuropharmacology, neurophysiology, and behavioral neuroscience, with recent focus on dopamine pathways, cortical-dopaminergic interactions, and drug mechanisms in brain disorders. Notable studies include investigations into VMAT2 inhibitors for movement disorders and BOD1’s role in cerebellar circuitry. No scientific awards are explicitly mentioned in the provided text.