Yan Cui

Professor Yan Cui is a tumor immunologist affiliated with Augusta University's Medical College of Georgia, where they hold appointments in the Department of Biochemistry and Molecular Biology, Georgia Cancer Center, and Department of Neuroscience and Regenerative Medicine. Their research focuses on tumor microenvironment dynamics, immunosuppressive mechanisms, and novel cancer immunotherapy strategies.

• Specialized in CD73-adenosinergic signaling as immune checkpoint
• Investigated p53 dysfunction in tumor-immune interactions
• Characterized cancer-associated fibroblasts' role in immunosuppression

Research spans Head and Neck Squamous Cell Carcinoma and Colorectal Cancer, utilizing preclinical mouse models and clinical specimens with AI-assisted spatial analysis. Publications reveal expertise in immune checkpoint blockade, tumor progression mechanisms, and COX2-PGE2 axis regulation of T cell responses.

Scientific awards include:

• AAI Laboratory Travel Grant (2011)
• Cancer Research Institute Fellowship (2000)
• Alberta Cancer Board Fellowship (1996)

Active in NIH grant reviews and institutional committees including Georgia Cancer Center Flow Cytometry Core (2017–present) and AU Institutional Biosafety Committee (2020–2024).