Yair M. Botbol

Dr. Yair M. Botbol is a Research Assistant Professor in the Department of Pathology at Albert Einstein College of Medicine. His research focuses on autophagy and T cell function, particularly the interplay between cytokine signaling and autophagy regulation in immune responses. His lab investigates how autophagy-deficient T cells behave in non-lymphoid organs and explores novel autophagy regulators. He has contributed to understanding mechanisms linking autophagy to T cell activation, anergy prevention, and metabolic reprogramming.

Key research areas include immunology, cell biology, molecular biology, and autophagy's role in disease. His work spans from fundamental mechanisms of cellular processes to translational insights into HIV pathogenesis and metabolic disorders.

Publications highlight contributions to epigenetic regulation, HIV integration dynamics, and autophagy's role in immune tolerance. While no formal awards are listed, his research has been published in high-impact journals like Nature and Nature Immunology. He collaborates widely, with projects addressing T cell biology, chromatin remodeling, and disease models.