معرفی
Xuebin Qin is Professor of Microbiology and Immunology at Tulane University, based at the Tulane National Primate Research Center in Covington, LA. His research integrates immunology with translational applications for HIV therapy and cardiovascular disease.
Education:
- MD, Wannan Medical College, Wuhu, China (1986)
- MS, Tongji Medical University, Wuhan, China (1991)
- PhD, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China (1996)
Dr. Qin's work centers on innate immunity mechanisms, particularly complement system dysregulation and monocyte activation in HIV pathogenesis and associated cardiovascular complications. His lab pioneered CD59-targeted inhibitors for HIV therapy, established causal links between membrane attack complex (MAC) formation and atherosclerosis, and developed a universal cell ablation platform using intermedilysin for dissecting immune cell functions in tissue regeneration and disease models.
Analysis of his 2008-2024 publications reveals consistent focus on complement-mediated pathologies across virology (HIV, COVID-19) and cardiovascular research, with increasing emphasis on translational tools like the CD59 ablation system. His work bridges molecular immunology with therapeutic development, particularly in exploiting complement vulnerabilities for infectious disease and cancer treatment.
Scientific Awards:
- Spirit of Tulane Award, Tulane University (2023)
- Tulane Convergence Award, Tulane University (2022)
- Poster of Distinction Award, Brigham and Women’s Hospital (2003)
- Junior Investigator Travel Award, American Heart Association (2008)
- Travel Award, Federation of Clinical Immunology Societies (2008)
Dr. Qin leads multiple NIH-funded research programs including therapeutic anti-hCD59 development for HIV/cancer, universal cell ablation models, and HIV-associated cardiovascular disease mechanisms. He maintains extensive collaborations with Tulane National Primate Research Center faculty to identify latent HIV reservoirs in nonhuman primates and studies renal macrophage dynamics using novel ablation techniques.
His laboratory operates within Tulane National Primate Research Center's specialized infrastructure, utilizing transgenic mouse models and nonhuman primate systems to investigate endothelial regeneration, macrophage trafficking, and HIV persistence mechanisms in controlled biosafety environments.
