Xiaoyang Zhu

Xiaoyang Zhu is a Researcher in the Department of Veterinary and Biomedical Sciences at Pennsylvania State University. Their work focuses on molecular mechanisms of peroxisome proliferator-activated receptor (PPAR) signaling in hepatocarcinogenesis and fatty acid metabolism.

• University: Pennsylvania State University
• Department: Veterinary and Biomedical Sciences
• Email: xzz145@psu.edu

Research Interests: Zhu investigates PPAR receptor activation, species differences in drug toxicity, and age-dependent metabolic pathways in liver cancer development. Key areas include:

• PPAR-α and PPARβ/δ receptor signaling
• Perinatal exposure effects on carcinogenesis
• Species-specific responses in humanized and transgenic mouse models
• Linoleic acid and fatty acid metabolic dysregulation
• Agonist-receptor interactions in toxicology

Publication Trends: Recent work (2021-2025) examines PPAR agonists in toxicology, focusing on perfluorinated compounds, keratinocyte signaling, and metabolic profiling in transgenic models.

Labs and Collaborations: Zhu collaborates with teams led by Dr. Jeffrey M. Peters (Penn State) on receptor signaling studies and environmental toxicology research.